PDB: 2596 件ウェブページステータス検索Chemie searchBIRD

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7RV2	Crystal structure of the BCL6 BTB domain in complex with OICR-8828 分子名称: B-cell lymphoma 6 protein, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Kuntz, D.A, Prive, G.G. 登録日 2021-08-18 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Crystal structure of the BCL6 BTB domain in complex with OICR-8828 To Be Published
7RUX	Crystal structure of the BCL6 BTB domain in complex with OICR-8311 分子名称: B-cell lymphoma 6 protein, FORMIC ACID, N-(3-chloropyridin-4-yl)-2-(3-(cyclopropylmethyl)-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)acetamide 著者 Kuntz, D.A, Prive, G.G. 登録日 2021-08-18 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of the BCL6 BTB domain in complex with OICR-8311 To Be Published
7RUW	Crystal structure of the BCL6 BTB domain in complex with OICR-7859 分子名称: 2-(2-amino-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-N-(3-chloropyridin-4-yl)acetamide, B-cell lymphoma 6 protein, CHLORIDE ION, ... 著者 Kuntz, D.A, Prive, G.G. 登録日 2021-08-18 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of the BCL6 BTB domain in complex with OICR-7859 To Be Published
7RUZ	Crystal structure of the BCL6 BTB domain in complex with OICR-8445 分子名称: 2-[2-(benzylamino)-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-N-(3-chloropyridin-4-yl)acetamide, B-cell lymphoma 6 protein, CHLORIDE ION, ... 著者 Kuntz, D.A, Prive, G.G. 登録日 2021-08-18 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Crystal structure of the BCL6 BTB domain in complex with OICR-8445 To Be Published
7RV1	Crystal structure of the BCL6 BTB domain in complex with OICR-8826 分子名称: (E)-3-(7-(2-((3-chloropyridin-4-yl)amino)-2-oxoethyl)-3-(3-(1-methyl-1H-pyrazol-4-yl)prop-2-yn-1-yl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)acrylamide, B-cell lymphoma 6 protein, DIMETHYL SULFOXIDE, ... 著者 Kuntz, D.A, Prive, G.G. 登録日 2021-08-18 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Crystal structure of the BCL6 BTB domain in complex with OICR-8826 To Be Published
7RUY	Crystal structure of the BCL6 BTB domain in complex with OICR-8388 分子名称: B-cell lymphoma 6 protein, FORMIC ACID, N-(3-chloropyridin-4-yl)-2-(2-{[(2,4-dimethoxyphenyl)methyl]amino}-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)acetamide 著者 Kuntz, D.A, Prive, G.G. 登録日 2021-08-18 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Crystal structure of the BCL6 BTB domain in complex with OICR-8388 To Be Published
3HUU	Crystal structure of transcription regulator like protein from Staphylococcus haemolyticus 分子名称: Transcription regulator like protein 著者 Agarwal, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-06-15 公開日 2009-07-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of transcription regulator like protein from Staphylococcus haemolyticus To be Published
7LZR	Crystal structure of the BCL6 BTB domain in complex with OICR-10256 分子名称: B-cell lymphoma 6 protein, CHLORIDE ION, GLYCEROL, ... 著者 Kuntz, D.A, Prive, G.G. 登録日 2021-03-10 公開日 2022-03-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Crystal structure of the BCL6 BTB domain in complex with OICR-10256 To Be Published
7M4T	Menin bound to M-1121 分子名称: Menin, methyl {(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-{1-[(3-methoxy-1-{4-[(1S,4S)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptane-2-sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}ethyl]cyclopentyl}carbamate, praseodymium triacetate 著者 Stuckey, J. 登録日 2021-03-22 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression. J.Med.Chem., 64, 2021
7N40	Crystal structure of LIN9-RbAp48-LIN37, a MuvB subcomplex 分子名称: Histone-binding protein RBBP4, Isoform 2 of Protein lin-9 homolog, Protein lin-37 homolog 著者 Asthana, A, Ramanan, P, Tripathi, S.M, Rubin, S.M. 登録日 2021-06-02 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes. Nat Commun, 13, 2022
7AX1	Crystal structure of the human CCR4-CAF1 complex 分子名称: CCR4-NOT transcription complex subunit 6, CCR4-NOT transcription complex subunit 7, MAGNESIUM ION 著者 Chen, Y, Khazina, E, Weichenrieder, O. 登録日 2020-11-09 公開日 2021-05-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex. Nucleic Acids Res., 49, 2021
7M3X	Crystal Structure of the Apo Form of Human RBBP7 分子名称: Histone-binding protein RBBP7, UNKNOWN ATOM OR ION 著者 Righetto, G.L, Dong, A, Li, Y, Hutchinson, A, Seitova, A, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) 登録日 2021-03-19 公開日 2021-05-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Crystal Structure of the Apo Form of Human RBBP7 To Be Published
6FTO	Crystal structure of the Chp2 chromoshadow domain in complex with N-terminal domain of chromatin remodeler Mit1 分子名称: Chromatin remodeling factor mit1, Chromo domain-containing protein 2, HEXANE-1,6-DIOL 著者 Leopold, K, Schalch, T. 登録日 2018-02-22 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Transcriptional gene silencing requires dedicated interaction between HP1 protein Chp2 and chromatin remodeler Mit1. Genes Dev., 33, 2019
6GKO	Mouse thymidylate synthase cocrystallized with dUMP and soaked in phenolphthalein 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one, DIMETHYL SULFOXIDE, ... 著者 Maj, P, Wilk, P, Jarmula, A, Weiss, M.S, Rode, W. 登録日 2018-05-21 公開日 2019-06-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.839 Å) 主引用文献 Thymidylate synthase fragment screening To Be Published
6H1C	Structure of Ferric uptake regulator from Pseudomonas aeruginosa with manganese. 分子名称: Ferric uptake regulation protein, MANGANESE (II) ION, ZINC ION 著者 Nader, S, Perard, J, Carpentier, P, Michaud-Soret, I, Crouzy, S. 登録日 2018-07-11 公開日 2019-07-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Ferric uptake regulator with Mn and Zn form Pseudomonas aeruginosa To Be Published
6GYJ	Mouse thymidylate synthase crystal soaked in phenolphthalein 分子名称: 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one, DIMETHYL SULFOXIDE, SULFATE ION, ... 著者 Maj, P, Jarmula, A, Wilk, P, Weiss, M.S, Rode, W. 登録日 2018-06-30 公開日 2019-08-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Thymidylate synthase fragment screening To be published
3ZHO	X-ray structure of E.coli Wrba in complex with FMN at 1.2 A resolution 分子名称: FLAVIN MONONUCLEOTIDE, FLAVOPROTEIN WRBA 著者 Kishko, I, Lapkouski, M, Brynda, J, Kuty, M, Carey, J, Smatanova, I.K, Ettrich, R. 登録日 2012-12-23 公開日 2013-08-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 1.2 A Resolution Crystal Structure of Escherichia Coli Wrba Holoprotein Acta Crystallogr.,Sect.D, 69, 2013
3DVP	Pak1 peptide bound LC8 分子名称: Dynein light chain 1, cytoplasmic, P21 activated Kinase peptide 著者 Lightcap, C.M, Williams, J.C. 登録日 2008-07-18 公開日 2009-01-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Biochemical and structural characterization of the Pak1-LC8 interaction. J.Biol.Chem., 283, 2008
5X5A	Human thymidylate synthase bound with phosphate ion 分子名称: PHOSPHATE ION, Thymidylate synthase 著者 Chen, D, Jansson, A, Larsson, A, Nordlund, P. 登録日 2017-02-15 公開日 2017-06-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
5X66	Human thymidylate synthase in complex with dUMP and methotrexate 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, METHOTREXATE, Thymidylate synthase 著者 Chen, D, Jansson, A, Larsson, A, Nordlund, P. 登録日 2017-02-21 公開日 2017-06-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
5X4Y	Mutant human thymidylate synthase M190K crystallized in a sulfate-containing condition 分子名称: SULFATE ION, Thymidylate synthase 著者 Chen, D, Jansson, A, Larsson, A, Nordlund, P. 登録日 2017-02-14 公開日 2017-06-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
5X5Q	Human thymidylate synthase complexed with dUMP and raltitrexed 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, TOMUDEX, Thymidylate synthase 著者 Chen, D, Jansson, A, Larsson, A, Nordlund, P. 登録日 2017-02-17 公開日 2017-06-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
3CFS	Structural basis of the interaction of RbAp46/RbAp48 with histone H4 分子名称: ARSENIC, Histone H4, Histone-binding protein RBBP7 著者 Murzina, N.V, Pei, X.-Y, Pratap, J.V, Sparkes, M, Vicente-Garcia, J, Ben-Shahar, T.R, Verreault, A, Luisi, B.F, Laue, E.D. 登録日 2008-03-04 公開日 2008-06-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46. Structure, 16, 2008
5X67	Human thymidylate synthase in complex with dUMP and nolatrexed 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-azanyl-6-methyl-5-pyridin-4-ylsulfanyl-3H-quinazolin-4-one, Thymidylate synthase 著者 Chen, D, Jansson, A, Larsson, A, Nordlund, P. 登録日 2017-02-21 公開日 2017-06-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states. J. Biol. Chem., 292, 2017
5X4X	Mutant human thymidylate synthase A191K crystallized in a sulfate-containing condition 分子名称: SULFATE ION, Thymidylate synthase 著者 Chen, D, Jansson, A, Larsson, A, Nordlund, P. 登録日 2017-02-14 公開日 2017-06-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017

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