PDB: 10140 件ウェブページステータス検索Chemie searchBIRD

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1BBD	THREE DIMENSIONAL STRUCTURE OF THE FAB FRAGMENT OF A NEUTRALIZING ANTIBODY TO HUMAN RHINOVIRUS SEROTYPE 2 分子名称: IGG2A-KAPPA 8F5 FAB (HEAVY CHAIN), IGG2A-KAPPA 8F5 FAB (LIGHT CHAIN), SULFATE ION 著者 Tormo, J, Blaas, D, Fita, I. 登録日 1992-05-05 公開日 1994-01-31 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Three-dimensional structure of the Fab fragment of a neutralizing antibody to human rhinovirus serotype 2. Protein Sci., 1, 1992
4LF3	Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor 分子名称: Fab heavy chain, Fab light chain, Glucagon receptor 著者 Murray, J.M, Mukund, S. 登録日 2013-06-26 公開日 2013-11-13 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.735 Å) 主引用文献 Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor. J.Biol.Chem., 288, 2013
4LRN	Ontogeny of recognition specificity and functionality for the anti-HIV antibody 4E10 分子名称: GEP 1 heavy chain, GEP 1 light chain 著者 Finton, K.A.K. 登録日 2013-07-20 公開日 2014-10-08 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10. Plos Pathog., 10, 2014
3X3G	Fab fragment from anti TRAIL-R2 Human Agonist Antibody KMTR2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Heavy chain of KMTR2, ... 著者 Tamada, T. 登録日 2015-01-20 公開日 2015-12-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 TRAIL-R2 Superoligomerization Induced by Human Monoclonal Agonistic Antibody KMTR2 Sci Rep, 5, 2015
3X3F	TRAIL-R2 Extracellular Region Complexed to a Fab fragment from Human Agonist Antibody KMTR2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... 著者 Tamada, T. 登録日 2015-01-20 公開日 2015-12-23 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 TRAIL-R2 Superoligomerization Induced by Human Monoclonal Agonistic Antibody KMTR2 Sci Rep, 5, 2015
4G6A	Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody AP33 分子名称: AP33 Heavy Chain, AP33 Light chain, E2 peptide 著者 Kong, L, Wilson, I.A, Law, M. 登録日 2012-07-18 公開日 2012-09-26 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33. J.Virol., 86, 2012
8JOW	Crystal structure of rabbit antibody with phosphorylated peptide bound 分子名称: ARG-PRO-HIS-PHE-PRO-GLN-PHE-SEP-TYR-SER-ALA-SER, Antibody (scFv), CHLORIDE ION 著者 Caaveiro, J.M.M, Kawade, R, Tsumoto, K. 登録日 2023-06-08 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Origin of high binding affinity and selectivity of phosphorylated epitope-specific rabbit antibodies To Be Published
8HGM	Structure of SARS-CoV-2 spike RBD in complex with neutralizing antibody NIV-11 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NIV-11 Fab heavy chain, NIV-11 Fab light chain, ... 著者 Moriyama, S, Anraku, Y, Muranishi, S, Adachi, Y, Kuroda, D, Higuchi, Y, Kotaki, R, Tonouchi, K, Yumoto, K, Suzuki, T, Kita, S, Someya, T, Fukuhara, H, Kuroda, Y, Yamamoto, T, Onodera, T, Fukushi, S, Maeda, K, Nakamura-Uchiyama, F, Hashiguchi, T, Hoshino, A, Maenaka, K, Takahashi, Y. 登録日 2022-11-15 公開日 2023-10-25 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants. Nat Commun, 14, 2023
6J9O	Crystal structure of a free scFv molecule from a group 2 influenza A viruses HA binding antibody AF4H1K1 分子名称: Heavy chain of AF4H1K1 scFv, Light chain of AF4H1K1 scFv 著者 Xiao, H.X, Qi, J.X, Gao, F.G. 登録日 2019-01-23 公開日 2020-01-29 最終更新日 2021-02-10 実験手法 X-RAY DIFFRACTION (1.397 Å) 主引用文献 Light chain modulates heavy chain conformation to change protection profile of monoclonal antibodies against influenza A viruses. Cell Discov, 5, 2019
7K90	Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C144 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C144 Fab Heavy Chain, C144 Fab Light Chain, ... 著者 Barnes, C.O, Esswein, S.R, Bjorkman, P.J. 登録日 2020-09-27 公開日 2020-10-21 最終更新日 2021-01-13 実験手法 ELECTRON MICROSCOPY (3.24 Å) 主引用文献 SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
3UJJ	Crystal structure of anti-HIV-1 V3 Fab 4025 in complex with Con A peptide 分子名称: ACETATE ION, Fab region of the heavy chain of anti-HIV-1 V3 monoclonal antibody 4025, GLYCEROL, ... 著者 Kong, X.P, Sampson, J. 登録日 2011-11-07 公開日 2011-12-28 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure. Plos One, 6, 2011
7K8X	Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ... 著者 Abernathy, M.E, Barnes, C.O, Bjorkman, P.J. 登録日 2020-09-27 公開日 2020-10-21 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
7K8Y	Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ... 著者 Abernathy, M.E, Barnes, C.O, Bjorkman, P.J. 登録日 2020-09-27 公開日 2020-10-21 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
7K8S	Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C002 (state 1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ... 著者 Barnes, C.O, Malyutin, A.G, Bjorkman, P.J. 登録日 2020-09-27 公開日 2020-10-21 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
1L7I	Crystal Structure of the anti-ErbB2 Fab2C4 分子名称: SULFATE ION, chimera of Fab2C4: "humanized" murine monoclonal antibody 著者 Vajdos, F.F, Adams, C.W, Breece, T.N, Presta, L.G, de Vos, A.M, Sidhu, S.S. 登録日 2002-03-15 公開日 2002-07-10 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis. J.Mol.Biol., 320, 2002
7K8V	Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C110 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C110 Fab Heavy Chain, ... 著者 Dam, K.A, Barnes, C.O, Bjorkman, P.J. 登録日 2020-09-27 公開日 2020-10-21 最終更新日 2021-01-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
7K8U	Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C104 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C104 Fab Heavy Chain, ... 著者 Barnes, C.O, Malyutin, A.G, Bjorkman, P.J. 登録日 2020-09-27 公開日 2020-10-21 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
7K8W	Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C119 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C119 Fab Heavy Chain, ... 著者 Sharaf, N.G, Barnes, C.O, Bjorkman, P.J. 登録日 2020-09-27 公開日 2020-10-21 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
3J93	Fitting of Fab into the cryoEM density map of EV71 procapsid in complex with Fab22A12 分子名称: neutralizing antibody 22A12, heavy chain, light chain 著者 Shingler, K.L, Cifuente, J.O, Ashley, R.E, Makhov, A.M, Conway, J.F, Hafenstein, S. 登録日 2014-12-02 公開日 2014-12-24 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (8.8 Å) 主引用文献 The enterovirus 71 procapsid binds neutralizing antibodies and rescues virus infection in vitro. J.Virol., 89, 2015
8ITU	SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 IgG. 分子名称: 1H1 heavy chain, 1H1 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. 登録日 2023-03-23 公開日 2023-04-12 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants. Commun Biol, 6, 2023
1IGF	CRYSTAL STRUCTURES OF AN ANTIBODY TO A PEPTIDE AND ITS COMPLEX WITH PEPTIDE ANTIGEN AT 2.8 ANGSTROMS 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IGG1-KAPPA B13I2 FAB (HEAVY CHAIN), IGG1-KAPPA B13I2 FAB (LIGHT CHAIN) 著者 Stanfield, R.L, Wilson, I.A. 登録日 1991-03-21 公開日 1992-04-15 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A. Science, 248, 1990
3J30	Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab CHK152 分子名称: CHK152 heavy chain, CHK152 light chain 著者 Sun, S, Xiang, Y, Rossmann, M.G. 登録日 2013-01-28 公開日 2013-04-24 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (16 Å) 主引用文献 Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization. Elife, 2, 2013
6XCM	Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2020-06-08 公開日 2020-07-01 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies. Cell, 182, 2020
6XCN	Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2020-06-08 公開日 2020-07-01 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.66 Å) 主引用文献 Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies. Cell, 182, 2020
7K8T	Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C002 (State 2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ... 著者 Malyutin, A.G, Barnes, C.O, Bjorkman, P.J. 登録日 2020-09-27 公開日 2020-10-21 最終更新日 2021-01-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020

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