PDB: 5470 件ウェブページステータス検索Chemie searchBIRD

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3R27	Crystal structure of the first RRM domain of heterogeneous nuclear ribonucleoprotein L (HnRNP L) 分子名称: GLYCEROL, Heterogeneous nuclear ribonucleoprotein L 著者 Zhang, W, Liu, Y, Zeng, F, Niu, L, Teng, M, Li, X. 登録日 2011-03-14 公開日 2011-09-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Crystal structure of the first RRM domain of heterogeneous nuclear ribonucleoprotein L (HnRNP L) To be Published
3RQE	Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD1 分子名称: Paxillin LD1 peptide, Programmed cell death protein 10 著者 Li, X, Zhang, R, Boggon, T.J. 登録日 2011-04-28 公開日 2011-06-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Molecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3). J.Biol.Chem., 286, 2011
1SVC	NFKB P50 HOMODIMER BOUND TO DNA 分子名称: DNA (5'-D(*AP*GP*AP*TP*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*CP*TP*A P*GP*A)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B (NF-KB)) 著者 Mueller, C.W, Harrison, S.C. 登録日 1995-11-27 公開日 1996-06-10 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the NF-kappa B p50 homodimer bound to DNA. Nature, 373, 1995
3RSE	Structural and biochemical characterization of two binding sites for nucleation promoting factor WASp-VCA on Arp2/3 complex 分子名称: Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, Actin-related protein 2/3 complex subunit 2, ... 著者 Pollard, T.D, Jurgenson, C.T, Ti, S, Nolen, B.J. 登録日 2011-05-02 公開日 2011-06-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex. Proc.Natl.Acad.Sci.USA, 108, 2011
3RAN	CANINE GDP-RAN Q69L MUTANT 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (GTP-BINDING NUCLEAR PROTEIN RAN) 著者 Stewart, M, Kent, H.M, Mccoy, A.J. 登録日 1998-10-19 公開日 1998-12-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2). J.Mol.Biol., 284, 1998
1UK1	Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor 分子名称: 5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE, Poly [ADP-ribose] polymerase-1 著者 Kinoshita, T. 登録日 2003-08-14 公開日 2004-09-14 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase J.Med.Chem., 47, 2004
3RDD	Human Cyclophilin A Complexed with an Inhibitor 分子名称: Peptidyl-prolyl cis-trans isomerase A, ethyl N-[(4-aminobenzyl)carbamoyl]glycinate 著者 Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. 登録日 2011-04-01 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
1UK0	Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase with a novel inhibitor 分子名称: 2-{3-[4-(4-FLUOROPHENYL)-3,6-DIHYDRO-1(2H)-PYRIDINYL]PROPYL}-8-METHYL-4(3H)-QUINAZOLINONE, Poly [ADP-ribose] polymerase-1 著者 Kinoshita, T. 登録日 2003-08-13 公開日 2004-01-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Inhibitor-induced structural change of the active site of human poly(ADP-ribose) polymerase. Febs Lett., 556, 2004
1SSF	Solution structure of the mouse 53BP1 fragment (residues 1463-1617) 分子名称: Transformation related protein 53 binding protein 1 著者 Charier, G, Couprie, J, Alpha-Bazin, B, Meyer, V, Quemeneur, E, Guerois, R, Callebaut, I, Gilquin, B, Zinn-Justin, S. 登録日 2004-03-24 公開日 2004-09-14 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The Tudor Tandem of 53BP1; A New Structural Motif Involved in DNA and RG-Rich Peptide Binding Structure, 12, 2004
1T6N	Crystal structure of the N-terminal domain of human UAP56 分子名称: CITRATE ANION, Probable ATP-dependent RNA helicase 著者 Zhao, R. 登録日 2004-05-06 公開日 2004-08-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Crystal Structure of UAP56, a DExD/H-Box Protein Involved in Pre-mRNA Splicing and mRNA Export Structure, 12, 2004
3RLN	Structural Basis of Cytosolic DNA Recognition by Innate Immune Receptors 分子名称: Gamma-interferon-inducible protein 16 著者 Jin, T.C, Xiao, T. 登録日 2011-04-19 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.251 Å) 主引用文献 Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor. Immunity, 36, 2012
1UK5	Solution structure of the Murine BAG domain of Bcl2-associated athanogene 3 分子名称: BAG-family molecular chaperone regulator-3 著者 Hatta, R, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-08-19 公開日 2004-02-19 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange Structure, 18, 2010
3R21	Design, synthesis, and biological evaluation of pyrazolopyridine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (Part I) 分子名称: MAGNESIUM ION, N-(2-aminoethyl)-N-{5-[(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide, Serine/threonine-protein kinase 6 著者 Zhang, L, Fan, J, Chong, J.-H, Cesena, A, Tam, B, Gilson, C, Boykin, C, Wang, D, Marcotte, D, Le Brazidec, J.-Y, Aivazian, D, Piao, J, Lundgren, K, Hong, K, Vu, K, Nguyen, K. 登録日 2011-03-11 公開日 2011-08-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I). Bioorg.Med.Chem.Lett., 21, 2011
1UL1	Crystal structure of the human FEN1-PCNA complex 分子名称: Flap endonuclease-1, MAGNESIUM ION, Proliferating cell nuclear antigen 著者 Sakurai, S, Kitano, K, Yamaguchi, H, Hamada, K, Okada, K, Fukuda, K, Uchida, M, Ohtsuka, E, Morioka, H, Hakoshima, T. 登録日 2003-09-05 公開日 2005-03-01 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for recruitment of human flap endonuclease 1 to PCNA EMBO J., 24, 2005
1UPV	Crystal structure of the human Liver X receptor beta ligand binding domain in complex with a synthetic agonist 分子名称: N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, OXYSTEROLS RECEPTOR LXR-BETA 著者 Hoerer, S, Schmid, A, Heckel, A, Budzinski, R.M, Nar, H. 登録日 2003-10-13 公開日 2004-10-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of the Human Liver X Receptor Beta Ligand-Binding Domain in Complex with a Synthetic Agonist J.Mol.Biol., 334, 2003
3RLO	Structural Basis of Cytosolic DNA Recognition by Innate Receptors 分子名称: 1,2-ETHANEDIOL, FORMIC ACID, Gamma-interferon-inducible protein 16 著者 Jin, T.C, Xiao, T. 登録日 2011-04-19 公開日 2012-04-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor. Immunity, 36, 2012
3O2T	Crystal structure of the N-terminal domain of human Symplekin 分子名称: 1,2-ETHANEDIOL, Symplekin 著者 Tong, L, Xiang, K, Xiang, S. 登録日 2010-07-22 公開日 2010-10-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex. Nature, 467, 2010
3NNC	Crystal Structure of CUGBP1 RRM1/2-RNA Complex 分子名称: CUGBP Elav-like family member 1, RNA (5'-R(*UP*GP*UP*GP*UP*GP*UP*UP*GP*UP*GP*UP*G)-3') 著者 Teplova, M, Song, J, Gaw, H, Teplov, A, Patel, D.J. 登録日 2010-06-23 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2005 Å) 主引用文献 Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1. Structure, 18, 2010
3RZX	Mouse importin alpha-Ku70 NLS peptide complex 分子名称: Importin subunit alpha-2, Ku70 NLS peptide 著者 Takeda, A.A.S, Fontes, M.R.M. 登録日 2011-05-12 公開日 2011-08-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structural basis of importin-alpha-mediated nuclear transport for Ku70 and Ku80. J.Mol.Biol., 412, 2011
1UPW	Crystal structure of the human Liver X receptor beta ligand binding domain in complex with a synthetic agonist 分子名称: N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, OXYSTEROLS RECEPTOR LXR-BETA 著者 Hoerer, S, Schmid, A, Heckel, A, Budzinski, R.M, Nar, H. 登録日 2003-10-13 公開日 2004-10-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Human Liver X Receptor Beta Ligand-Binding Domain in Complex with a Synthetic Agonist J.Mol.Biol., 334, 2003
3S01	Crystal structure of a Heterogeneous nuclear ribonucleoprotein L (Hnrpl) from Mus musculus at 2.15 A resolution 分子名称: GLYCEROL, Heterogeneous nuclear ribonucleoprotein L, ISOPROPYL ALCOHOL 著者 Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL), Partnership for T-Cell Biology (TCELL) 登録日 2011-05-12 公開日 2011-06-29 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of a Heterogeneous nuclear ribonucleoprotein L (Hnrpl) from Mus musculuS at 2.15 A resolution To be published
3S7R	Crystal structure of a Heterogeneous nuclear ribonucleoprotein A/B (HNRPAB) from HOMO SAPIENS at 2.15 A resolution 分子名称: Heterogeneous nuclear ribonucleoprotein A/B, UNKNOWN LIGAND 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL), Partnership for Stem Cell Biology (STEMCELL) 登録日 2011-05-26 公開日 2011-08-10 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of a Heterogeneous nuclear ribonucleoprotein A/B (HNRPAB) from Homo sapiens at 2.15 A resolution To be published
3KFC	Complex Structure of LXR with an agonist 分子名称: 4-{3-[3-(methylsulfonyl)phenoxy]phenyl}-8-(trifluoromethyl)quinoline, Oxysterols receptor LXR-beta 著者 Olland, A, Bernotas, R.C, Unwalla, R. 登録日 2009-10-27 公開日 2009-12-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 4-(3-Aryloxyaryl)quinoline sulfones are potent liver X receptor agonists. Bioorg.Med.Chem.Lett., 20, 2010
3KB7	Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor 分子名称: 8-{[2-methoxy-5-(4-methylpiperazin-1-yl)phenyl]amino}-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide, L(+)-TARTARIC ACID, Serine/threonine-protein kinase PLK1, ... 著者 Bossi, R.T, Bertrand, J.A. 登録日 2009-10-20 公開日 2010-05-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors J.Med.Chem., 53, 2010
3KUP	Crystal Structure of the CBX3 Chromo Shadow Domain 分子名称: Chromobox protein homolog 3, UNKNOWN ATOM OR ION 著者 Tempel, W, Li, Z, Li, Y, Kozieradzki, I, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) 登録日 2009-11-27 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Crystal Structure of the CBX3 Chromo Shadow Domain to be published

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