PDB: 7755 件ウェブページステータス検索Chemie searchBIRD

---

2C0Y	THE CRYSTAL STRUCTURE OF A CYS25ALA MUTANT OF HUMAN PROCATHEPSIN S 分子名称: PROCATHEPSIN S 著者 Kaulmann, G, Palm, G.J, Schilling, K, Hilgenfeld, R, Wiederanders, B. 登録日 2005-09-08 公開日 2006-11-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Crystal Structure of a Cys25 -> Ala Mutant of Human Procathepsin S Elucidates Enzyme-Prosequence Interactions. Protein Sci., 15, 2006
5EZP	Human transthyretin (TTR) complexed with 4-hydroxy-chalcone 分子名称: 1,2-ETHANEDIOL, 4-hydroxy-chalcone, Transthyretin 著者 Polsinelli, I, Nencetti, S, Shepard, W.E, Orlandini, E, Stura, E.A. 登録日 2015-11-26 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A new crystal form of human transthyretin obtained with a curcumin derived ligand. J.Struct.Biol., 194, 2016
5FFP	Crystal structure of CdiI from Burkholderia dolosa AUO158 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Immunity 23 family protein 著者 Michalska, K, Stols, L, Eschenfeldt, W, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) 登録日 2015-12-18 公開日 2016-01-20 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CdiI from Burkholderia dolosa AUO158 To Be Published
8B53	Structure of porcine pancreatic elastase bound to a fragment of a 4-azaindole inhibitor 分子名称: 3-methylbenzoic acid, CALCIUM ION, Chymotrypsin-like elastase family member 1, ... 著者 Ferraroni, M, Gerace, A. 登録日 2022-09-21 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 X-ray structural study of human neutrophil elastase inhibition with a series of azaindoles, azaindazoles and isoxazolones J.Mol.Struct., 1274, 2023
5E3E	Crystal structure of CdiA-CT/CdiI complex from Y. kristensenii 33638 分子名称: CdiI immunity protein, Large exoprotein involved in heme utilization or adhesion, SODIUM ION 著者 Michalska, K, Joachimiak, G, Jedrzejczak, R, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) 登録日 2015-10-02 公開日 2015-11-25 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The CDI toxin of Yersinia kristensenii is a novel bacterial member of the RNase A superfamily. Nucleic Acids Res., 45, 2017
5HKQ	Crystal structure of CDI complex from Escherichia coli STEC_O31 分子名称: CdiI immunity protein, Contact-dependent inhibitor A 著者 Michalska, K, Stols, L, Eschenfeldt, W, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) 登録日 2016-01-14 公開日 2017-01-18 最終更新日 2020-03-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Functional plasticity of antibacterial EndoU toxins. Mol.Microbiol., 109, 2018
5T87	Crystal structure of CDI complex from Cupriavidus taiwanensis LMG 19424 分子名称: CdiA toxin, CdiI immunity protein 著者 Michalska, K, Joachimiak, G, Jedrzejczak, R, Hayes, C.S, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) 登録日 2016-09-06 公開日 2017-09-13 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016). Proteins, 86 Suppl 1, 2018
5J3E	Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA 分子名称: 5-methylcytosine containing DNA, Thymocyte nuclear protein 1, UNKNOWN ATOM OR ION 著者 Halabelian, L, Tempel, W, Li, Y, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) 登録日 2016-03-30 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA To be published
3SFM	Novel crystallization conditions for tandem variant R67 DHFR yields wild-type crystal structure 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, Dihydrofolate reductase type 2 著者 Yachnin, B.J, Berghuis, A.M. 登録日 2011-06-13 公開日 2011-11-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure. Acta Crystallogr.,Sect.F, 67, 2011
3TU5	Actin complex with Gelsolin Segment 1 fused to Cobl segment 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... 著者 Kudryashov, D.S, Sawaya, M.R, Durer, Z.A.O. 登録日 2011-09-15 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural States and dynamics of the d-loop in actin. Biophys.J., 103, 2012
1SAZ	Membership in the ASKHA Superfamily: Enzymological Properties and Crystal Structure of Butyrate Kinase 2 from Thermotoga maritima 分子名称: FORMIC ACID, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Probable butyrate kinase 2, ... 著者 Diao, J, Cooper, D.R, Sanders, D.A, Hasson, M.S. 登録日 2004-02-09 公開日 2005-03-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of butyrate kinase 2 from Thermotoga maritima, a member of the ASKHA superfamily of phosphotransferases. J.Bacteriol., 191, 2009
6AHS	Mouse Kallikrein 7 in complex with imidazolinylindole derivative 分子名称: 1-[(2-chlorophenyl)sulfonyl]-5-methyl-3-[(4R)-2-methyl-4,5-dihydro-1H-imidazol-4-yl]-1H-indole, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... 著者 Sugawara, H. 登録日 2018-08-20 公開日 2019-01-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors. Bioorg. Med. Chem. Lett., 29, 2019
7NUY	New polymorhp of proteinase K obtained by free interface diffusion technique 分子名称: Proteinase K, SULFATE ION 著者 Gavira, J.A, Artusio, F, Castellvi, A, Pisano, R. 登録日 2021-03-15 公開日 2022-01-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Tuning Transport Phenomena in Agarose Gels for the Control of Protein Nucleation Density and Crystal Form Crystals, 2021
7S83	Crystal structure of SARS CoV-2 Spike Receptor Binding Domain in complex with shark neutralizing VNARs ShAb01 and ShAb02 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ShAb01 VNAR, ... 著者 Chen, W.-H, Hajduczki, A, Dooley, H.M, Joyce, M.G. 登録日 2021-09-17 公開日 2022-11-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity. Nat Commun, 14, 2023
7SIF	Crystal Structure of HLA B*3505 in complex with NPDIVIYQY, an 9-mer epitope from HIV-I 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-2-microglobulin, ... 著者 Gras, S, Lobos, C.A, Chatzileontiadou, D.S.M. 登録日 2021-10-14 公開日 2022-11-23 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Molecular insights into the HLA-B35 molecules' classification associated with HIV control. Immunol.Cell.Biol., 102, 2024
7NS7	Human L-alanine:glyoxylate aminotransferase minor allele variant: AGXT-Mi (P11L-I340M) 分子名称: L-alanine:glyoxylate aminotransferase 著者 Cellini, B, Dindo, M. 登録日 2021-03-05 公開日 2022-03-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase. Protein Sci., 31, 2022
7SJF	Structure of Dehaloperoxidase B in Complex with Thymol 分子名称: 5-METHYL-2-(1-METHYLETHYL)PHENOL, Dehaloperoxidase B, GLYCEROL, ... 著者 Ghiladi, R.A, de Serrano, V.S, Malewschik, T, Yun, D. 登録日 2021-10-17 公開日 2022-11-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 The Multifunctional Globin Dehaloperoxidase as a Biocatalyst in the Oxidation of Monoterpenes To Be Published
5LPR	STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS 分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION 著者 Fujishige, A, Bone, R, Agard, D.A. 登録日 1991-08-05 公開日 1993-01-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991
7Q66	Cryo-em structure of the Nup98 fibril polymorph 3 分子名称: Nuclear pore complex protein Nup98 著者 Ibanez de Opakua, A, Geraets, J.A, Frieg, B, Dienemann, C, Savastano, A, Rankovic, M, Cima-Omori, M.-S, Schroeder, G.F, Zweckstetter, M. 登録日 2021-11-05 公開日 2022-10-12 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.79 Å) 主引用文献 Molecular interactions of FG nucleoporin repeats at high resolution. Nat.Chem., 14, 2022
7XO1	Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient 分子名称: Alpha-synuclein 著者 Fan, Y, Sun, Y.P, Wang, J, Liu, C. 登録日 2022-04-30 公開日 2022-11-30 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease. Structure, 31, 2023
7C4X	Crystal structure of germination protease from the spore-forming bacterium Paenisporosarcina sp. TG-20 in its inactive form 分子名称: germination protease 著者 Lee, J.H, Lee, C.W. 登録日 2020-05-18 公開日 2021-03-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural insights into the psychrophilic germinal protease PaGPR and its autoinhibitory loop. J.Microbiol, 58, 2020
7XO2	Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient 分子名称: Alpha-synuclein 著者 Fan, Y, Sun, Y.P, Wang, J, Liu, C. 登録日 2022-04-30 公開日 2022-11-30 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease. Structure, 31, 2023
7SAS	Cryo-EM structure of TMEM106B fibrils extracted from a FTLD-TDP patient, polymorph 3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B 著者 Cao, Q, Jiang, Y, Sawaya, M.R, Eisenberg, D.S. 登録日 2021-09-23 公開日 2022-03-09 最終更新日 2022-05-25 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43. Nature, 605, 2022
7SAQ	Cryo-EM structure of TMEM106B fibrils extracted from a FTLD-TDP patient, polymorph 1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B 著者 Cao, Q, Jiang, Y, Sawaya, M.R, Eisenberg, D.S. 登録日 2021-09-23 公開日 2022-03-09 最終更新日 2022-05-25 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43. Nature, 605, 2022
7SAR	Cryo-EM structure of TMEM106B fibrils extracted from a FTLD-TDP patient, polymorph 2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B 著者 Cao, Q, Jiang, Y, Sawaya, M.R, Eisenberg, D.S. 登録日 2021-09-23 公開日 2022-03-09 最終更新日 2022-05-25 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43. Nature, 605, 2022

<70717273747576777879808182838485>