PDB: 2005 件ウェブページステータス検索Chemie searchBIRD

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3D23	Main protease of HCoV-HKU1 分子名称: 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE 著者 Zhao, Q, Chen, C, Li, S, Zou, Y. 登録日 2008-05-07 公開日 2008-09-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the main protease from a global infectious human coronavirus, HCoV-HKU1. J.Virol., 82, 2008
1R09	HUMAN RHINOVIRUS 14 COMPLEXED WITH ANTIVIRAL COMPOUND R 61837 分子名称: 3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE, DIMETHYL SULFOXIDE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), ... 著者 Chapman, M.S, Minor, I, Rossmann, M.G, Diana, G.D, Andries, K. 登録日 1990-05-04 公開日 1991-10-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Human rhinovirus 14 complexed with antiviral compound R 61837. J.Mol.Biol., 217, 1991
3C6D	The pseudo-atomic structure of dengue immature virus 分子名称: Polyprotein, prM 著者 Li, L. 登録日 2008-02-04 公開日 2008-04-08 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (12.5 Å) 主引用文献 The flavivirus precursor membrane-envelope protein complex: structure and maturation Science, 319, 2008
1COV	COXSACKIEVIRUS B3 COAT PROTEIN 分子名称: COXSACKIEVIRUS COAT PROTEIN, MYRISTIC ACID, PALMITIC ACID 著者 Muckelbauer, J.K, Rossmann, M.G. 登録日 1994-10-19 公開日 1996-03-08 最終更新日 2023-04-19 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structure determination of coxsackievirus B3 to 3.5 A resolution. Acta Crystallogr.,Sect.D, 51, 1995
2LVG	NMR structure of HCV Non-structural protein AB, NS4B(1-40) 分子名称: Non-structural protein 4B 著者 Montserret, R, Penin, F. 登録日 2012-07-05 公開日 2013-06-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Aminoterminal Amphipathic alpha-Helix AH1 of Hepatitis C Virus Nonstructural Protein 4B Possesses a Dual Role in RNA Replication and Virus Production. Plos Pathog., 10, 2014
2ZJO	Crystal structure of hepatitis C virus NS3 helicase with a novel inhibitor 分子名称: Genome polyprotein, N-[4-(BIS{4-[(3-SULFOPHENYL)AMINO]PHENYL}METHYLENE)CYCLOHEXA-2,5-DIEN-1-YLIDENE]-4-SULFOBENZENAMINIUM 著者 Liaw, S.H, Chen, S.J, Hu, C.Y, Chi, W.K, Chu, I.D, Hwang, L.H, Chern, J.W, Chen, D.S. 登録日 2008-03-07 公開日 2009-03-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-Based Discovery of Triphenylmethane Derivatives as Novel Inhibitors of Hepatitis C Virus Helicase To be Published
1POV	ROLE AND MECHANISM OF THE MATURATION CLEAVAGE OF VP0 IN POLIOVIRUS ASSEMBLY: STRUCTURE OF THE EMPTY CAPSID ASSEMBLY INTERMEDIATE AT 2.9 ANGSTROMS RESOLUTION 分子名称: MYRISTIC ACID, POLIOVIRUS NATIVE EMPTY CAPSID (TYPE 1), SPHINGOSINE 著者 Basavappa, R, Filman, D.J, Hogle, J.M. 登録日 1995-08-10 公開日 1995-12-07 最終更新日 2023-04-19 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty capsid assembly intermediate at 2.9 A resolution. Protein Sci., 3, 1994
7FEJ	Complex of FMDV A/AF/72 and bovine neutralizing scFv antibody R55 分子名称: A/AF/72 VP1, A/AF/72 VP2, A/AF/72 VP3, ... 著者 He, Y, Li, K, Lou, Z. 登録日 2021-07-20 公開日 2021-09-29 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization. J.Virol., 95, 2021
3D62	Development of Broad-Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CLpro 分子名称: 3C-like proteinase, benzyl (2-oxopropyl)carbamate 著者 Bacha, U, Barrila, J, Gabelli, S.B, Kiso, Y, Amzel, L.M, Freire, E. 登録日 2008-05-18 公開日 2008-07-01 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Development of broad-spectrum halomethyl ketone inhibitors against coronavirus main protease 3CL(pro). Chem.Biol.Drug Des., 72, 2008
1RMU	THREE-DIMENSIONAL STRUCTURES OF DRUG-RESISTANT MUTANTS OF HUMAN RHINOVIRUS 14 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ... 著者 Badger, J, Krishnaswamy, S, Kremer, M.J, Oliveira, M.A, Rossmann, M.G, Heinz, B.A, Rueckert, R.R, Dutko, F.J, Mckinlay, M.A. 登録日 1988-10-03 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Three-dimensional structures of drug-resistant mutants of human rhinovirus 14. J.Mol.Biol., 207, 1989
2WV9	Crystal Structure of the NS3 protease-helicase from Murray Valley encephalitis virus 分子名称: FLAVIVIRIN PROTEASE NS2B REGULATORY SUBUNIT, FLAVIVIRIN PROTEASE NS3 CATALYTIC SUBUNIT 著者 Assenberg, R, Mastrangelo, E, Walter, T.S, Verma, A, Milani, M, Owens, R.J, Stuart, D.I, Grimes, J.M, Mancini, E.J. 登録日 2009-10-15 公開日 2009-12-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal Structure of a Novel Conformational State of the Flavivirus Ns3 Protein: Implications for Polyprotein Processing and Viral Replication. J.Virol., 83, 2009
2LZQ	Structure of NS2(32-57) GBVB protein 分子名称: NS2 peptide 著者 Montserret, R, Penin, F, Martin, A. 登録日 2012-10-08 公開日 2014-04-09 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NS2 Proteins of GB Virus B and Hepatitis C Virus Share Common Protease Activities and Membrane Topologies. J.Virol., 88, 2014
4L3B	X-ray structure of the HRV2 A particle uncoating intermediate 分子名称: Protein VP1, Protein VP2, Protein VP3 著者 Vives-Adrian, L, Querol-Audi, J, Garriga, D, Pous, J, Verdaguer, N. 登録日 2013-06-05 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (6.5 Å) 主引用文献 Uncoating of common cold virus is preceded by RNA switching as determined by X-ray and cryo-EM analyses of the subviral A-particle. Proc.Natl.Acad.Sci.USA, 110, 2013
2YOL	West Nile Virus NS2B-NS3 protease in complex with 3,4- dichlorophenylacetyl-Lys-Lys-GCMA 分子名称: (S)-6-amino-N-((S)-6-amino-1-(((1r,4S)-4-guanidinocyclohexyl)methylamino)-1-oxohexan-2-yl)-2-(2-(3,4-dichlorophenyl)acetamido)hexanamide, CHLORIDE ION, NICKEL (II) ION, ... 著者 Hammamy, M.Z, Haase, C, Hammami, M, Hilgenfeld, R, Steinmetzer, T. 登録日 2012-10-25 公開日 2013-03-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Development and Characterization of New Peptidomimetic Inhibitors of the West Nile Virus Ns2B-Ns3 Protease. Chemmedchem, 8, 2013
1AR9	P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT H2142Y 分子名称: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE 著者 Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M. 登録日 1997-08-11 公開日 1997-12-03 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural studies of poliovirus mutants that overcome receptor defects. Nat.Struct.Biol., 4, 1997
7FJT	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAM) 分子名称: CITRIC ACID, Core protein, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
1AR6	P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT V1160I +P1095S 分子名称: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE 著者 Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M. 登録日 1997-08-11 公開日 1997-12-03 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural studies of poliovirus mutants that overcome receptor defects. Nat.Struct.Biol., 4, 1997
1BCV	SYNTHETIC PEPTIDE CORRESPONDING TO THE MAJOR IMMUNOGEN SITE OF FMD VIRUS, NMR, 10 STRUCTURES 分子名称: PEPTIDE CORRESPONDING TO THE MAJOR IMMUNOGEN SITE OF FMD VIRUS 著者 Petit, M.C, Benkirane, N, Guichard, G, Phan Chan Du, A, Cung, M.T, Briand, J.P, Muller, S. 登録日 1998-05-03 公開日 1998-11-25 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of a retro-inverso peptide analogue mimicking the foot-and-mouth disease virus major antigenic site. Structural basis for its antigenic cross-reactivity with the parent peptide. J.Biol.Chem., 274, 1999
2MKB	Structure of NS2(113-137) GBVB protein 分子名称: Protease NS2-3 著者 Montserret, R, Martin, A, Penin, F. 登録日 2014-02-04 公開日 2014-05-07 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NS2 Proteins of GB Virus B and Hepatitis C Virus Share Common Protease Activities and Membrane Topologies. J.Virol., 88, 2014
2KWT	Solution structure of NS2 [27-59] 分子名称: Protease NS2-3 著者 Montserret, R, Bartenschlager, R, Penin, F. 登録日 2010-04-19 公開日 2011-03-02 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly. Plos Pathog., 6, 2010
2KWZ	Solution structure of NS2 [60-99] 分子名称: Protease NS2-3 著者 Montserret, R, Bartenschlager, R, Penin, F. 登録日 2010-04-22 公開日 2011-03-02 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly. Plos Pathog., 6, 2010
1PVC	REFINEMENT OF THE SABIN STRAIN OF TYPE 3 POLIOVIRUS AT 2.4 ANGSTROMS AND THE CRYSTAL STRUCTURES OF ITS VARIANTS AT 2.9 ANGSTROMS RESOLUTION 分子名称: MYRISTIC ACID, POLIOVIRUS TYPE 3, SABIN STRAIN, ... 著者 Syed, R, Filman, D.J, Hogle, J.M. 登録日 1995-03-30 公開日 1995-09-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Refinement of the Sabin Strain of Type 3 Poliovirus at 2.4 Angstroms and the Crystal Structures of its Variants at 2.9 Angstroms Resolution To be Published
2LTO	TDRD3 complex 分子名称: DNA-directed RNA polymerase II subunit RPB1, Tudor domain-containing protein 3 著者 Sikorsky, T. 登録日 2012-05-30 公開日 2013-01-16 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Recognition of asymmetrically dimethylated arginine by TDRD3. Nucleic Acids Res., 40, 2012
6E0Q	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 4,6-dihydroxy-2-methyl-5-oxocyclohepta-1,3,6-triene-1-carboxylic acid 分子名称: 1,2-ETHANEDIOL, 4,6-dihydroxy-2-methyl-5-oxocyclohepta-1,3,6-triene-1-carboxylic acid, MANGANESE (II) ION, ... 著者 Dick, B.L, Morrison, C.N, Cohen, S.M. 登録日 2018-07-06 公開日 2018-11-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease. J. Med. Chem., 61, 2018
6DZQ	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid 分子名称: 1,2-ETHANEDIOL, 3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid, MANGANESE (II) ION, ... 著者 Dick, B.L, Morrison, C.N, Cohen, S.M. 登録日 2018-07-05 公開日 2018-11-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease. J. Med. Chem., 61, 2018

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