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7AHO
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RUVBL1-RUVBL2 heterohexameric ring after binding of RNA helicase DHX34
分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
著者Lopez-Perrote, A, Rodriguez, C.F, Llorca, O.
登録日2020-09-25
公開日2020-11-25
実験手法ELECTRON MICROSCOPY (4.18 Å)
主引用文献Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM.
Elife, 9, 2020
7AOA
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Structure of the extended MTA1/HDAC1/MBD2/RBBP4 NURD deacetylase complex
分子名称: Histone deacetylase 1, Histone-binding protein RBBP4, INOSITOL HEXAKISPHOSPHATE, ...
著者Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R.
登録日2020-10-14
公開日2020-11-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (19.4 Å)
主引用文献The topology of chromatin-binding domains in the NuRD deacetylase complex.
Nucleic Acids Res., 48, 2020
7MWW
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Structure of hepatitis C virus envelope full-length glycoprotein 2 (eE2) from J6 genotype
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2A12 Fab Heavy chain, ...
著者Kumar, A, Hossain, R.A, Yost, S.A, Bu, W, Wang, Y, Dearborn, A.D, Grakoui, A, Cohen, J.I, Marcotrigiano, J.
登録日2021-05-17
公開日2021-09-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural insights into hepatitis C virus receptor binding and entry.
Nature, 598, 2021
7NLG
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S. cerevisiae Ty1 p22 restriction factor, Gag CA-CTD, AUG2 variant A273V mutant
分子名称: Ty1 Gag p22
著者Cottee, M.A, Taylor, I.A.
登録日2021-02-22
公開日2021-10-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.528 Å)
主引用文献Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control.
Nat Commun, 12, 2021
7NPF
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Vibrio cholerae ParA2-ATPyS-DNA filament
分子名称: AAA family ATPase, DNA (49-MER), MAGNESIUM ION, ...
著者Parker, A.V, Bergeron, J.R.C.
登録日2021-02-26
公開日2021-10-06
最終更新日2021-10-20
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献The structure of the bacterial DNA segregation ATPase filament reveals the conformational plasticity of ParA upon DNA binding.
Nat Commun, 12, 2021
7NLH
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S. cerevisiae Ty1 p22 restriction factor, Gag CA-CTD, AUG1 variant
分子名称: Ty1 Gag p22
著者Cottee, M.A, Taylor, I.A.
登録日2021-02-22
公開日2021-10-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control.
Nat Commun, 12, 2021
7MKD
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BU of 7mkd by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Saecker, R.M, Darst, S.A, Chen, J.
登録日2021-04-23
公開日2021-09-29
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MJQ
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Vascular KATP channel: Kir6.1 SUR2B quatrefoil-like conformation 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-sensitive inward rectifier potassium channel 8, ...
著者Sung, M.W, Shyng, S.L.
登録日2021-04-20
公開日2021-10-13
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MJO
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Vascular KATP channel: Kir6.1 SUR2B quatrefoil-like conformation 1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ...
著者Sung, M.W, Shyng, S.L.
登録日2021-04-20
公開日2021-10-13
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides.
Proc.Natl.Acad.Sci.USA, 118, 2021
3ZFE
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BU of 3zfe by Molmil
Human enterovirus 71 in complex with capsid binding inhibitor WIN51711
分子名称: CHLORIDE ION, SODIUM ION, SPHINGOSINE, ...
著者Plevka, P, Perera, R, Yap, M.L, Cardosa, J, Kuhn, R.J, Rossmann, M.G.
登録日2012-12-11
公開日2013-03-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of Human Enterovirus 71 in Complex with a Capsid-Binding Inhibitor.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ZVJ
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Crystal structure of high molecular weight (HMW) form of Peroxiredoxin I from Schistosoma mansoni
分子名称: THIOREDOXIN PEROXIDASE
著者Saccoccia, F, Angelucci, F, Bellelli, A, Boumis, G, Brunori, M, Miele, A.E.
登録日2011-07-25
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Moonlighting by Different Stressors: Crystal Structure of the Chaperone Species of a 2-Cys Peroxiredoxin.
Structure, 20, 2012
7LBA
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BU of 7lba by Molmil
E. coli Agmatinase
分子名称: Agmatinase, MANGANESE (II) ION
著者Chitrakar, I, Ahmed, S.F, Torelli, A.T, French, J.B.
登録日2021-01-07
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the E. coli agmatinase, SPEB.
Plos One, 16, 2021
7LT3
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BU of 7lt3 by Molmil
NHEJ Long-range synaptic complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (30-MER), DNA (31-MER), ...
著者He, Y, Chen, S.
登録日2021-02-18
公開日2021-04-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis of long-range to short-range synaptic transition in NHEJ.
Nature, 593, 2021
7LSX
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BU of 7lsx by Molmil
Cryo-EM structure of 13S proteasome core particle assembly intermediate purified from Pre3-1 proteasome mutant (G34D)
分子名称: Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ...
著者Schnell, H.M, Walsh Jr, R.M, Rawson, S, Hanna, J.W.
登録日2021-02-18
公開日2021-04-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis.
Nat.Struct.Mol.Biol., 28, 2021
3ZL5
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Crystal structure of Schistosoma mansoni Peroxiredoxin I C48S mutant with one decamer in the ASU
分子名称: DI(HYDROXYETHYL)ETHER, PEROXIREDOXIN I, SULFATE ION
著者Saccoccia, F, Angelucci, F, Ardini, M, Boumis, G, Brunori, M, DiLeandro, L, Ippoliti, R, Miele, A.E, Natoli, G, Scotti, S, Bellelli, A.
登録日2013-01-28
公開日2013-09-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.493 Å)
主引用文献Switching between the Alternative Structures and Functions of a 2-Cys Peroxiredoxin, by Site-Directed Mutagenesis
J.Mol.Biol., 425, 2013
7L9Y
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Human PARP14 (ARTD8), catalytic fragment in complex with RBN012042
分子名称: 1,2-ETHANEDIOL, 7-(cyclopentylamino)-5-fluoro-2-{[(piperidin-4-yl)sulfanyl]methyl}quinazolin-4(3H)-one, CHLORIDE ION, ...
著者Dorsey, B.W, Swinger, K.K, Schenkel, L.B, Church, W.D, Perl, N.R, Vasbinder, M.M, Wigle, T.J, Kuntz, K.W.
登録日2021-01-05
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule.
Chembiochem, 22, 2021
7LWC
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BU of 7lwc by Molmil
Goat beta-lactoglobulin mutant Q59A
分子名称: Beta-lactoglobulin
著者Munoz, D.A, Dobson, R.C.J.
登録日2021-02-28
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Engineering food proteins for improved digestibility and lower allergenicity: a case study using caprine beta-lactoglobulin
To Be Published
7LUN
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Human PARP14 (ARTD8), catalytic fragment in complex with RBN011980
分子名称: 7-(cyclopentylamino)-5-fluoro-2-{[(trans-4-hydroxycyclohexyl)sulfanyl]methyl}quinazolin-4(3H)-one, CHLORIDE ION, GLYCEROL, ...
著者Dorsey, B.W, Swinger, K.K, Schenkel, L.B, Church, W.D, Perl, N.R, Vasbinder, M.M, Wigle, T.J, Kuntz, K.W.
登録日2021-02-22
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule.
Chembiochem, 22, 2021
3ZNJ
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BU of 3znj by Molmil
Crystal structure of unliganded ClcF from R.opacus 1CP in crystal form 1.
分子名称: 1,2-ETHANEDIOL, 5-CHLOROMUCONOLACTONE DEHALOGENASE, CHLORIDE ION
著者Roth, C, Groening, J.A.D, Kaschabek, S.R, Schloemann, M, Straeter, N.
登録日2013-02-14
公開日2013-03-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure and Catalytic Mechanism of Chloromuconolactone Dehalogenase Clcf from Rhodococcus Opacus 1Cp.
Mol.Microbiol., 88, 2013
4BXL
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BU of 4bxl by Molmil
Structure of alpha-synuclein in complex with an engineered binding protein
分子名称: ALPHA SYNUCLEIN, AS69
著者Mirecka, E.A, Shaykhalishahi, H, Lecher, J, Stoldt, M, Hoyer, W.
登録日2013-07-12
公開日2014-05-21
実験手法SOLUTION NMR
主引用文献Sequestration of a Beta-Hairpin for Control of Alpha-Synuclein Aggregation.
Angew.Chem.Int.Ed.Engl., 53, 2014
7N4Y
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BU of 7n4y by Molmil
The structure of bovine thyroglobulin with iodinated tyrosines
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kim, K, Clarke, O.B.
登録日2021-06-04
公開日2021-11-10
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献The structure of natively iodinated bovine thyroglobulin.
Acta Crystallogr D Struct Biol, 77, 2021
7KF4
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BU of 7kf4 by Molmil
Crystal structure from SARS-CoV-2 NendoU NSP15
分子名称: CITRIC ACID, Uridylate-specific endoribonuclease
著者Godoy, A.S, Nakamura, A.M, Pereira, H.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliveira, K.I.Z, Oliva, G.
登録日2020-10-13
公開日2020-12-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 2023
7KHB
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Escherichia coli RNA polymerase and rrnBP1 promoter open complex
分子名称: CHAPSO, DNA (60-MER), DNA (64-MER), ...
著者Shin, Y, Qayyum, M.Z, Murakami, K.S.
登録日2020-10-20
公開日2020-10-28
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
4B2C
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Structure of the factor Xa-like trypsin variant triple-Ala (TPA) in complex with eglin C
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ...
著者Menzel, A, Neumann, P, Stubbs, M.T.
登録日2012-07-13
公開日2012-08-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Thermodynamic signatures in macromolecular interactions involving conformational flexibility.
Biol.Chem., 395, 2014
7KQY
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Crystal Structure and Characterization of Human Heavy-Chain only Antibodies reveals a novel, stable dimeric structure similar to Monoclonal Antibodies
分子名称: Heavy-Chain only Human Antibodies
著者Bahmanjah, S, Mieczkowski, C, Yu, Y, Baker, J, Raghunathan, G, Tomazela, D, Hsieh, M, Mccoy, M, Strickland, C, Fayadat-Dilman, L.
登録日2020-11-18
公開日2020-12-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.913 Å)
主引用文献Crystal Structure and Characterization of Human Heavy-Chain Only Antibodies Reveals a Novel, Stable Dimeric Structure Similar to Monoclonal Antibodies.
Antibodies, 9, 2020

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