8P96
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![BU of 8p96 by Molmil](/molmil-images/mine/8p96) | TARGET COMPLEX 3 | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, 1,2-Distearoyl-sn-glycerophosphoethanolamine, N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, ... | 著者 | Garau, G. | 登録日 | 2023-06-05 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | TARGET COMPLEX 2 To Be Published
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6YBL
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![BU of 6ybl by Molmil](/molmil-images/mine/6ybl) | Structure of MBP-Mcl-1 in complex with compound 9m | 分子名称: | (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-[2-[[2-(2-methoxyphenyl)pyrimidin-4-yl]methoxy]phenyl]propanoic acid, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Dokurno, P, Surgenor, A.E, Murray, J.B. | 登録日 | 2020-03-17 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor. J.Med.Chem., 63, 2020
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4WJL
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![BU of 4wjl by Molmil](/molmil-images/mine/4wjl) | Structure of human dipeptidyl peptidase 10 (DPPY): a modulator of neuronal Kv4 channels | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Inactive dipeptidyl peptidase 10, ... | 著者 | Bezerra, G.A, Dobrovetsky, E, Seitova, A, Fedosyuk, S, Dhe-Paganon, S, Gruber, K. | 登録日 | 2014-09-30 | 公開日 | 2015-03-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure of human dipeptidyl peptidase 10 (DPPY): a modulator of neuronal Kv4 channels. Sci Rep, 5, 2015
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8P90
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![BU of 8p90 by Molmil](/molmil-images/mine/8p90) | TARGET COMPLEX 2 | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, 1,2-Distearoyl-sn-glycerophosphoethanolamine, N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, ... | 著者 | Garau, G. | 登録日 | 2023-06-05 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | TARGET COMPLEX 2 To Be Published
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8P6B
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![BU of 8p6b by Molmil](/molmil-images/mine/8p6b) | |
8OLS
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![BU of 8ols by Molmil](/molmil-images/mine/8ols) | |
4WMS
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![BU of 4wms by Molmil](/molmil-images/mine/4wms) | STRUCTURE OF APO MBP-MCL1 AT 1.9A | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, MAGNESIUM ION, ... | 著者 | Clifton, M.C, Dranow, D.M. | 登録日 | 2014-10-09 | 公開日 | 2015-05-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1. Plos One, 10, 2015
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8P9X
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![BU of 8p9x by Molmil](/molmil-images/mine/8p9x) | Vitamin D receptor complex with Xe4Me agonist ligand | 分子名称: | (1~{R},3~{S},5~{Z})-5-[(2~{E})-2-[(1~{S},3~{a}~{S},7~{a}~{S})-1,7~{a}-dimethyl-1-(5-methyl-5-oxidanyl-hexa-1,3-diynyl)-2,3,3~{a},5,6,7-hexahydroinden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, ACETATE ION, Nuclear receptor coactivator 2, ... | 著者 | Rochel, N. | 登録日 | 2023-06-06 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | A vitamin D-based strategy overcomes chemoresistance in prostate cancer. Br.J.Pharmacol., 2024
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8OM0
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![BU of 8om0 by Molmil](/molmil-images/mine/8om0) | Structure of Oceanobacillus iheyensis group II intron in the presence of Na+, Mg2+ and intronistat B | 分子名称: | 3,4,5-trihydroxybenzoic acid, Domains 1-5, MAGNESIUM ION, ... | 著者 | Silvestri, I, Marcia, M. | 登録日 | 2023-03-31 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (3.61 Å) | 主引用文献 | Targeting the conserved active site of splicing machines with specific and selective small molecule modulators. Nat Commun, 15, 2024
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8OLY
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![BU of 8oly by Molmil](/molmil-images/mine/8oly) | |
6GPA
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![BU of 6gpa by Molmil](/molmil-images/mine/6gpa) | Beta-1,4-galactanase from Bacteroides thetaiotaomicron with galactose | 分子名称: | Arabinogalactan endo-beta-1,4-galactanase, beta-D-galactopyranose | 著者 | Hekelaar, J, Boger, M, Leeuwen van, S.S, Lammerts van Bueren, A, Dijkhuizen, L. | 登録日 | 2018-06-05 | 公開日 | 2018-12-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structural and functional characterization of a family GH53 beta-1,4-galactanase from Bacteroides thetaiotaomicron that facilitates degradation of prebiotic galactooligosaccharides. J. Struct. Biol., 205, 2019
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8OLZ
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![BU of 8olz by Molmil](/molmil-images/mine/8olz) | Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+, 5'-exon, and intronistat B after 2h30 soaking | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-exon, DOMAINS 1-5, ... | 著者 | Silvestri, I, Marcia, M. | 登録日 | 2023-03-30 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Targeting the conserved active site of splicing machines with specific and selective small molecule modulators. Nat Commun, 15, 2024
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8PC4
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![BU of 8pc4 by Molmil](/molmil-images/mine/8pc4) | MEMBRANE TARGET COMPLEX 1 | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, ... | 著者 | Garau, G. | 登録日 | 2023-06-09 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | MEMBRANE TARGET COMPLEX 1 To Be Published
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1BDM
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![BU of 1bdm by Molmil](/molmil-images/mine/1bdm) | |
8OVC
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![BU of 8ovc by Molmil](/molmil-images/mine/8ovc) | Respiratory supercomplex (III2-IV2) from Mycobacterium smegmatis | 分子名称: | (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | 著者 | Kovalova, T, Krol, S, Sjostrand, D, Riepl, D, Gamiz-Hernandez, A, Brzezinski, P, Kaila, V, Hogbom, M. | 登録日 | 2023-04-25 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Long-range charge transfer mechanism of the III 2 IV 2 mycobacterial supercomplex. Nat Commun, 15, 2024
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8OL8
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6Y62
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![BU of 6y62 by Molmil](/molmil-images/mine/6y62) | Crystal structure of the envelope glycoprotein complex of Maporal virus in a prefusion conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein,Envelope polyprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Serris, A, Rey, F.A, Guardado-Calvo, P. | 登録日 | 2020-02-26 | 公開日 | 2020-10-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism. Cell, 183, 2020
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8OKD
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8P6H
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![BU of 8p6h by Molmil](/molmil-images/mine/8p6h) | Bovine naive ultralong antibody AbBLV5B8* collected at 100K | 分子名称: | Antibody BLV5B8* heavy chain, Antibody BLV5B8* light chain | 著者 | Clarke, J.D, Douangamath, A, Mikolajek, H, Stuart, D.I, Owens, R.J. | 登録日 | 2023-05-26 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | The impact of chain-exchange on bovine ultralong immunoglobulins. Acta Crystallographica Section F, 2023
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8P2T
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![BU of 8p2t by Molmil](/molmil-images/mine/8p2t) | Bovine naive ultralong antibody AbD08* collected at 100K | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, Antibody D08* heavy chain, Antibody D08* light chain, ... | 著者 | Clarke, J.D, Douangamath, A, Mikolajek, H, Stuart, D.I, Owens, R.J. | 登録日 | 2023-05-16 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | The impact of chain-exchange on bovine ultralong immunoglobulins. Acta Crystallographica Section F, 2024
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8PZ6
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![BU of 8pz6 by Molmil](/molmil-images/mine/8pz6) | crystal structure of VDR in complex with D-Bishomo-1a,25-dihydroxyvitamin D3 analog 56 | 分子名称: | (1~{R},3~{R})-5-[(2~{E})-2-[(4~{a}~{R},5~{S},9~{a}~{S})-4~{a}-methyl-5-[(2~{R})-6-methyl-6-oxidanyl-heptan-2-yl]-3,4,5,6,7,8,9,9~{a}-octahydro-2~{H}-benzo[7]annulen-1-ylidene]ethylidene]-2-(3-oxidanylpropylidene)cyclohexane-1,3-diol, Nuclear receptor coactivator 2, Vitamin D3 receptor A | 著者 | Rochel, N. | 登録日 | 2023-07-27 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Design, synthesis, and biological activity of D-bishomo-1 alpha ,25-dihydroxyvitamin D 3 analogs and their crystal structures with the vitamin D nuclear receptor. Eur.J.Med.Chem., 271, 2024
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8QAA
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![BU of 8qaa by Molmil](/molmil-images/mine/8qaa) | |
7AV1
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![BU of 7av1 by Molmil](/molmil-images/mine/7av1) | LTA4 hydrolase in complex with fragment2 | 分子名称: | 2-[5-(4-methoxyphenyl)-1,2,3,4-tetrazol-2-yl]ethanamine, ACETATE ION, IMIDAZOLE, ... | 著者 | Srinivas, H. | 登録日 | 2020-11-03 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A 4 Hydrolase. J.Med.Chem., 64, 2021
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8PNQ
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8POH
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![BU of 8poh by Molmil](/molmil-images/mine/8poh) | |