5KKW
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4O5F
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8I8J
| Crystal structure of the ternary complex of Phosphopantetheine adenylyltransferase (PPAT) from Enterobacter sp. with Coenzyme-A and Phosphonoacetic acid at 2.07 A resolution. | 分子名称: | 1,2-ETHANEDIOL, COENZYME A, GLYCEROL, ... | 著者 | Ahmad, N, Sharma, P, Sharma, S, Singh, T.P. | 登録日 | 2023-02-04 | 公開日 | 2023-03-01 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Crystal structure of the ternary complex of Phosphopantetheine adenylyltransferase (PPAT) from Enterobacter sp. with Coenzyme-A and Phosphonoacetic acid at 2.07 A resolution. To Be Published
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2RM6
| Glutathione peroxidase-type tryparedoxin peroxidase, reduced form | 分子名称: | Glutathione peroxidase-like protein | 著者 | Melchers, J, Feher, K, Diechtierow, M, Krauth-Siegel, L, Muhle-Goll, C. | 登録日 | 2007-10-09 | 公開日 | 2008-07-29 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for a distinct catalytic mechanism in Trypanosoma brucei tryparedoxin peroxidase J.Biol.Chem., 283, 2008
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6GVN
| Tubulin:TM-3 DARPin complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Gigant, B, Cantos Fernandes, S, Campanacci, V. | 登録日 | 2018-06-21 | 公開日 | 2019-04-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Insight into microtubule nucleation from tubulin-capping proteins. Proc.Natl.Acad.Sci.USA, 116, 2019
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6SNL
| (R)-selective amine transaminase from Exophiala sideris | 分子名称: | CHLORIDE ION, GLYCEROL, HEXAETHYLENE GLYCOL, ... | 著者 | Telzerow, A, Hakansson, M, Steiner, K. | 登録日 | 2019-08-26 | 公開日 | 2020-12-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.129 Å) | 主引用文献 | Expanding the Toolbox of R-Selective Amine Transaminases by Identification and Characterization of New Members. Chembiochem, 22, 2021
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5AK6
| ligand complex structure of soluble epoxide hydrolase | 分子名称: | 2-[(5-CHLORO-2-PYRIDYL)SULFANYL]ETHANOL, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DI(HYDROXYETHYL)ETHER, ... | 著者 | Oster, L, Tapani, S, Xue, Y, Kack, H. | 登録日 | 2015-03-02 | 公開日 | 2015-05-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
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6RX6
| Trypanosoma brucei PTR1 (TbPTR1) in complex with inhibitor 4 (NMT-C0026) | 分子名称: | ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pteridine reductase, ... | 著者 | Landi, G, Pozzi, C, Mangani, S. | 登録日 | 2019-06-07 | 公開日 | 2020-07-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.11 Å) | 主引用文献 | Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1. J.Med.Chem., 65, 2022
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5YNX
| Structure of house dust mite allergen Der f 21 in PEG400 | 分子名称: | Allergen Der f 21, BETA-MERCAPTOETHANOL, GLYCEROL, ... | 著者 | Ng, C.L, Chew, F.T, Pang, S.L, Ho, K.L, Teh, A.H, Waterman, J, Rambo, R, Mathavan, I, Beis, K, Say, Y.H. | 登録日 | 2017-10-25 | 公開日 | 2019-03-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Crystal structure and epitope analysis of house dust mite allergen Der f 21. Sci Rep, 9, 2019
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6SOZ
| Glycosylated Trypanosoma brucei transferrin receptor in complex with human transferrin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, ... | 著者 | Trevor, C, Carrington, M, Higgins, M.K. | 登録日 | 2019-08-30 | 公開日 | 2019-11-06 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion. Nat Microbiol, 4, 2019
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1RP1
| DOG PANCREATIC LIPASE RELATED PROTEIN 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PANCREATIC LIPASE RELATED PROTEIN 1 | 著者 | Roussel, A, Cambillau, C. | 登録日 | 1998-04-02 | 公開日 | 1998-06-17 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Reactivation of the totally inactive pancreatic lipase RP1 by structure-predicted point mutations. Proteins, 32, 1998
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5FTO
| Crystal structure of the ALK kinase domain in complex with Entrectinib | 分子名称: | ALK TYROSINE KINASE RECEPTOR, Entrectinib | 著者 | Bossi, R, Canevari, G, Fasolini, M, Menichincheri, M, Ardini, E, Magnaghi, P, Avanzi, N, Banfi, P, Buffa, L, Ceriani, L, Colombo, M, Corti, L, Donati, D, Felder, E, Fiorelli, C, Fiorentini, F, Galvani, A, Isacchi, A, Lombardi Borgia, A, Marchionni, C, Nesi, M, Orrenius, C, Panzeri, A, Perrone, E, Pesenti, E, Rusconi, L, Saccardo, M.B, Vanotti, E, Orsini, P. | 登録日 | 2016-01-14 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Discovery of Entrectinib: A New 3-Aminoindazole as a Potent Anaplastic Lymphoma Kinase (Alk), C-Ros Oncogene 1 Kinase (Ros1), and Pan-Tropomyosin Receptor Kinases (Pan-Trks) Inhibitor. J.Med.Chem., 59, 2016
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3K80
| Structure of essential protein from Trypanosoma brucei | 分子名称: | Antibody, MP18 RNA editing complex protein | 著者 | Wu, M. | 登録日 | 2009-10-13 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies. J.Struct.Biol., 174, 2011
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3FKZ
| X-ray structure of the non covalent swapped form of the S16G/T17N/A19P/A20S/K31C/S32C mutant of bovine pancreatic ribonuclease | 分子名称: | Ribonuclease pancreatic | 著者 | Merlino, A, Russo Krauss, I, Perillo, M, Mattia, C.A, Ercole, C, Picone, D, Vergara, A, Sica, F. | 登録日 | 2008-12-18 | 公開日 | 2009-03-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants Biopolymers, 91, 2009
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2YIA
| Structure of the RNA polymerase VP1 from Infectious Pancreatic Necrosis Virus | 分子名称: | POTASSIUM ION, RNA-DIRECTED RNA POLYMERASE | 著者 | Graham, S.C, Sarin, L.P, Bahar, M.W, Myers, R.A, Stuart, D.I, Bamford, D.H, Grimes, J.M. | 登録日 | 2011-05-11 | 公開日 | 2011-07-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | The N-Terminus of the RNA Polymerase from Infectious Pancreatic Necrosis Virus is the Determinant of Genome Attachment. Plos Pathog., 7, 2011
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2YI8
| Structure of the RNA polymerase VP1 from Infectious Pancreatic Necrosis Virus | 分子名称: | CHLORIDE ION, POTASSIUM ION, RNA-DIRECTED RNA POLYMERASE | 著者 | Graham, S.C, Sarin, L.P, Bahar, M.W, Myers, R.A, Stuart, D.I, Bamford, D.H, Grimes, J.M. | 登録日 | 2011-05-11 | 公開日 | 2011-07-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The N-Terminus of the RNA Polymerase from Infectious Pancreatic Necrosis Virus is the Determinant of Genome Attachment. Plos Pathog., 7, 2011
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3FL0
| X-ray structure of the non covalent swapped form of the Q28L/K31C/S32C mutant of bovine pancreatic ribonuclease in complex with 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE | 分子名称: | 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE, Ribonuclease pancreatic | 著者 | Merlino, A, Russo Krauss, I, Perillo, M, Mattia, C.A, Ercole, C, Picone, D, Vergara, A, Sica, F. | 登録日 | 2008-12-18 | 公開日 | 2009-03-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants Biopolymers, 91, 2009
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5WHF
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4OYT
| Crystal structure of ternary complex of Plasmodium vivax SHMT with D-serine and folinic acid | 分子名称: | (2R)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-oxidanyl-propanoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... | 著者 | Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U. | 登録日 | 2014-02-13 | 公開日 | 2014-12-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of Plasmodium vivax serine hydroxymethyltransferase: implications for ligand-binding specificity and functional control. Acta Crystallogr.,Sect.D, 70, 2014
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3F8G
| The X-ray structure of a dimeric variant of human pancreatic ribonuclease with high cytotoxic and antitumor activities | 分子名称: | Ribonuclease pancreatic, SULFATE ION | 著者 | Merlino, A, Avella, G, Mazzarella, L, Sica, F. | 登録日 | 2008-11-12 | 公開日 | 2009-02-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant. Protein Sci., 18, 2009
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8TDI
| Structure of P2B11 Glucuronide-3-dehydrogenase | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, P2B11 Glucuronide-3-dehydrogenase, ... | 著者 | Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J. | 登録日 | 2023-07-03 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | An alternative broad-specificity pathway for glycan breakdown in bacteria. Nature, 631, 2024
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6R36
| T. brucei farnesyl pyrophosphate synthase (FPPS) | 分子名称: | DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, Farnesyl pyrophosphate synthase | 著者 | Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W. | 登録日 | 2019-03-19 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Fragment-Based Discovery of Non-bisphosphonate Binders of Trypanosoma brucei Farnesyl Pyrophosphate Synthase. Chembiochem, 21, 2020
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1VAH
| Crystal structure of the pig pancreatic-amylase complexed with r-nitrophenyl-a-D-maltoside | 分子名称: | Alpha-amylase, pancreatic, CALCIUM ION, ... | 著者 | Zhuo, H, Payan, F, Qian, M. | 登録日 | 2004-02-17 | 公開日 | 2005-04-26 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the pig pancreatic alpha-amylase complexed with rho-nitrophenyl-alpha-D-maltoside-flexibility in the active site Protein J., 23, 2004
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8CN5
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8CNE
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