PDB: 1957 件ウェブページステータス検索Chemie searchBIRD

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6FFS	Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors 分子名称: 3C Protease, SULFATE ION, ~{N}-[(2~{S},5~{S},14~{S})-2-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-9-methyl-3,8,15-tris(oxidanylidene)-1,4,9-triazacyclopentadec-14-yl]-5-methyl-1,2-oxazole-3-carboxamide 著者 Wiesmann, C, Farady, C. 登録日 2018-01-09 公開日 2018-02-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors. Bioorg. Med. Chem. Lett., 28, 2018
3RVB	The structure of HCV NS3 helicase (Heli-80) bound with inhibitor ITMN-3479 分子名称: CHLORIDE ION, MAGNESIUM ION, RNA helicase, ... 著者 Mather, O, Cheng, R, Schonfield, D, Barker, J. 登録日 2011-05-06 公開日 2014-09-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The structure of HCV NS3 helicase with inhibitor ITMN-3479 To be Published
1COV	COXSACKIEVIRUS B3 COAT PROTEIN 分子名称: COXSACKIEVIRUS COAT PROTEIN, MYRISTIC ACID, PALMITIC ACID 著者 Muckelbauer, J.K, Rossmann, M.G. 登録日 1994-10-19 公開日 1996-03-08 最終更新日 2023-04-19 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structure determination of coxsackievirus B3 to 3.5 A resolution. Acta Crystallogr.,Sect.D, 51, 1995
6FSB	Influenza B/Memphis/13/03 endonuclease with I38T mutation 分子名称: MAGNESIUM ION, MANGANESE (II) ION, Polymerase acidic protein 著者 Cusack, S, Speranzini, V. 登録日 2018-02-19 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep, 8, 2018
6FS8	Influenza B/Memphis/13/03 endonuclease with bound inhibitor, baloxavir acid (BXA) 分子名称: Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein 著者 Cusack, S, Speranzini, V. 登録日 2018-02-19 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep, 8, 2018
6FS9	Influenza B/Memphis/13/03 endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA) 分子名称: Baloxavir acid, CHLORIDE ION, MANGANESE (II) ION, ... 著者 Cusack, S, Speranzini, V. 登録日 2018-02-19 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep, 8, 2018
3L3H	X-ray crystal structure of the F6A mutant of influenza A acid polymerase epitope PA224 bound to murine H2-Db MHC 分子名称: 10-mer peptide from Polymerase acidic protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... 著者 Welland, A, Clements, C.S, Dunstone, M.A, Rossjohn, J. 登録日 2009-12-17 公開日 2010-03-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition Proc.Natl.Acad.Sci.USA, 107, 2010
4JZN	Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-1 分子名称: Anti-HCV E2 Fab HC84-1 heavy chain, Anti-HCV E2 Fab HC84-1 light chain, Envelope glycoprotein E2, ... 著者 Krey, T, Rey, F.A. 登録日 2013-04-03 公開日 2013-06-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape. Plos Pathog., 9, 2013
4IUM	Equine arteritis virus papain-like protease 2 (PLP2) covalently bound to ubiquitin 分子名称: GLYCEROL, Ubiquitin, ZINC ION, ... 著者 Bailey-Elkin, B.A, James, T.W, Mark, B.L. 登録日 2013-01-21 公開日 2013-02-13 最終更新日 2013-03-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells. Proc.Natl.Acad.Sci.USA, 110, 2013
4JZO	Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-27 分子名称: Anti-HCV E2 Fab HC84-27 heavy chain, Anti-HCV E2 Fab HC84-27 light chain, Envelope glycoprotein E2 著者 Krey, T, Rey, F.A. 登録日 2013-04-03 公開日 2013-06-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape. Plos Pathog., 9, 2013
6CFP	CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE 分子名称: 1-{1-[(4-fluorophenyl)methyl]-2-methyl-1H-imidazol-4-yl}ethan-1-one, DIMETHYL SULFOXIDE, Ubiquitin-like protein SMT3,Polymerase acidic protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-02-15 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE To Be Published
6FFN	Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors 分子名称: 3C protease, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Wiesmann, C, Farady, C. 登録日 2018-01-08 公開日 2018-02-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors. Bioorg. Med. Chem. Lett., 28, 2018
4A1X	Co-Complex structure of NS3-4A protease with the inhibitory peptide CP5-46-A (Synchrotron data) 分子名称: CHLORIDE ION, CP5-46-A PEPTIDE, NONSTRUCTURAL PROTEIN 4A, ... 著者 Schmelz, S, Kuegler, J, Collins, J, Heinz, D. 登録日 2011-09-20 公開日 2012-09-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 High Affinity Peptide Inhibitors of the Hepatitis C Virus Ns3-4A Protease Refractory to Common Resistant Mutants. J.Biol.Chem., 287, 2012
4IMZ	Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus 分子名称: Genome polyprotein, SODIUM ION, THIOCYANATE ION, ... 著者 Prasad, B.V.V, Muhaxhiri, Z, Deng, L, Shanker, S, Sankaran, B, Estes, M.K, Palzkill, T, Song, Y. 登録日 2013-01-03 公開日 2013-02-20 最終更新日 2013-04-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis of substrate specificity and protease inhibition in norwalk virus. J.Virol., 87, 2013
4A1V	Co-Complex structure of NS3-4A protease with the optimized inhibitory peptide CP5-46A-4D5E 分子名称: CHLORIDE ION, CP5-46A-4D5E, NON-STRUCTURAL PROTEIN 4A, ... 著者 Schmelz, S, Kuegler, J, Collins, J, Heinz, D.W. 登録日 2011-09-20 公開日 2012-09-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 High Affinity Peptide Inhibitors of the Hepatitis C Virus Ns3-4A Protease Refractory to Common Resistant Mutants. J.Biol.Chem., 287, 2012
4INH	Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus 分子名称: DIMETHYL SULFOXIDE, Genome polyprotein, peptide inhibitor, ... 著者 Prasad, B.V.V, Muhaxhiri, Z, Deng, L, Shanker, S, Sankaran, B, Estes, M.K, Palzkill, T, Song, Y. 登録日 2013-01-04 公開日 2013-02-20 最終更新日 2013-04-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis of substrate specificity and protease inhibition in norwalk virus. J.Virol., 87, 2013
2XYA	Non-covalent inhibtors of rhinovirus 3C protease. 分子名称: 2-PHENYLQUINOLIN-4-OL, PICORNAIN 3C 著者 Petersen, J, Edman, K, Edfeldt, F, Johansson, C. 登録日 2010-11-16 公開日 2011-04-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Non-Covalent Inhibitors of Rhinovirus 3C Protease. Bioorg.Med.Chem.Lett., 21, 2011
3U1I	Dengue virus protease covalently bound to a peptide 分子名称: SULFATE ION, Serine protease NS3, Serine protease subunit NS2B, ... 著者 Noble, C.G. 登録日 2011-09-29 公開日 2011-11-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Ligand-bound structures of the dengue virus protease reveal the active conformation J.Virol., 86, 2012
2HWK	Crystal Structure of Venezuelan Equine Encephalitis Alphavirus nsP2 Protease Domain 分子名称: FORMIC ACID, helicase nsP2 著者 Russo, A.T, White, M.A, Watowich, S.J. 登録日 2006-08-01 公開日 2006-09-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The Crystal Structure of the Venezuelan Equine Encephalitis Alphavirus nsP2 Protease. Structure, 14, 2006
1HXS	CRYSTAL STRUCTURE OF MAHONEY STRAIN OF POLIOVIRUS AT 2.2A RESOLUTION 分子名称: GENOME POLYPROTEIN, COAT PROTEIN VP1, COAT PROTEIN VP2, ... 著者 Miller, S.T, Hogle, J.M, Filman, D.J. 登録日 2001-01-16 公開日 2002-01-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Ab initio phasing of high-symmetry macromolecular complexes: successful phasing of authentic poliovirus data to 3.0 A resolution. J.Mol.Biol., 307, 2001
3U1J	Aprotinin bound to Dengue virus protease 分子名称: Pancreatic trypsin inhibitor, Serine protease NS3, Serine protease subunit NS2B 著者 Noble, C.G. 登録日 2011-09-30 公開日 2011-11-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Ligand-bound structures of the dengue virus protease reveal the active conformation J.Virol., 86, 2012
2LTO	TDRD3 complex 分子名称: DNA-directed RNA polymerase II subunit RPB1, Tudor domain-containing protein 3 著者 Sikorsky, T. 登録日 2012-05-30 公開日 2013-01-16 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Recognition of asymmetrically dimethylated arginine by TDRD3. Nucleic Acids Res., 40, 2012
2LZP	Structure of NS2(2-32) GBVB protein 分子名称: NS2 peptide 著者 Montserret, R, Penin, F, Martin, A. 登録日 2012-10-08 公開日 2014-04-09 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NS2 Proteins of GB Virus B and Hepatitis C Virus Share Common Protease Activities and Membrane Topologies. J.Virol., 88, 2014
1R08	STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES 分子名称: 5-(5-(2,6-DICHLORO-4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)PENTYL)-3-(HYDROXYETHYL OXYMETHYLENEOXYMETHYL) ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ... 著者 Badger, J, Smith, T.J, Rossmann, M.G. 登録日 1988-10-03 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses. Proteins, 6, 1989
1R09	HUMAN RHINOVIRUS 14 COMPLEXED WITH ANTIVIRAL COMPOUND R 61837 分子名称: 3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE, DIMETHYL SULFOXIDE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), ... 著者 Chapman, M.S, Minor, I, Rossmann, M.G, Diana, G.D, Andries, K. 登録日 1990-05-04 公開日 1991-10-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Human rhinovirus 14 complexed with antiviral compound R 61837. J.Mol.Biol., 217, 1991

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