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6U8Y
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Structure of the membrane-bound sulfane sulfur reductase (MBS), an archaeal respiratory membrane complex
分子名称: DUF4040 domain-containing protein, IRON/SULFUR CLUSTER, Monovalent cation/H+ antiporter subunit B, ...
著者Yu, H.J, Li, H.L.
登録日2019-09-06
公開日2020-09-09
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of the respiratory MBS complex reveals iron-sulfur cluster catalyzed sulfane sulfur reduction in ancient life.
Nat Commun, 11, 2020
6WFY
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Crystal structure of Fab224 in complex with NPNA4 peptide from circumsporozoite protein
分子名称: Fab224 heavy chain, Fab224 light chain, NPNA4 peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-04-04
公開日2020-07-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.226 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
8P94
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Cryo-EM structure of cortactin stabilized Arp2/3-complex nucleated actin branches
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
著者Liu, T, Moores, C.A.
登録日2023-06-05
公開日2024-01-03
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cortactin stabilizes actin branches by bridging activated Arp2/3 to its nucleated actin filament.
Nat.Struct.Mol.Biol., 31, 2024
6WPD
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NMR Structure of HSP1-NH2 antimicrobial peptide in presence of DPC-d38 micelles
分子名称: HSP1-NH2
著者Verly, R.M, Gomes, I.P.
登録日2020-04-27
公開日2020-09-02
最終更新日2020-09-16
実験手法SOLUTION NMR
主引用文献Membrane interactions of the anuran antimicrobial peptide HSP1-NH2: Different aspects of the association to anionic and zwitterionic biomimetic systems.
Biochim Biophys Acta Biomembr, 1863, 2020
6WPH
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BU of 6wph by Molmil
Structure of HIV-1 Reverse Transcriptase (RT) in complex with dsDNA and (-)-FTC
分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, DNA Primer 21-mer, DNA template 27-mer, ...
著者Bertoletti, N, Anderson, K.S.
登録日2020-04-27
公開日2020-11-04
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance.
Molecules, 25, 2020
6WPG
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BU of 6wpg by Molmil
Structural Basis of Salicylic Acid Perception by Arabidopsis NPR Proteins
分子名称: 2-HYDROXYBENZOIC ACID, Regulatory protein NPR4
著者Wang, W, Withers, J, Li, H, Zwack, P.J, Rusnac, D.V, Shi, H, Liu, L, Yan, S, Hinds, T.R, Guttman, M, Dong, X, Zheng, N.
登録日2020-04-27
公開日2020-08-12
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.283 Å)
主引用文献Structural basis of salicylic acid perception by Arabidopsis NPR proteins.
Nature, 586, 2020
6U9H
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Arabidopsis thaliana acetohydroxyacid synthase complex
分子名称: Acetolactate synthase small subunit 2, chloroplastic, Acetolactate synthase, ...
著者Guddat, L.W, Low, Y.S, Rao, Z.
登録日2019-09-08
公開日2020-07-15
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of fungal and plant acetohydroxyacid synthases.
Nature, 586, 2020
6WYU
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Crystallographic trimer of metal-free TriCyt2
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, HEME C, SULFATE ION, ...
著者Tezcan, F.A, Kakkis, A.
登録日2020-05-13
公開日2020-09-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Metal-Templated Design of Chemically Switchable Protein Assemblies with High-Affinity Coordination Sites.
Angew.Chem.Int.Ed.Engl., 59, 2020
6X0J
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Structure of reduced SidA ornithine hydroxylase with the FAD "in" and complexed with NADP and L-ornithine
分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-ornithine, L-ornithine N(5)-monooxygenase, ...
著者Tanner, J.J, Campbell, A.C.
登録日2020-05-15
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.335 Å)
主引用文献Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
6WP2
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The Crystal Structure of Apo Zinc-Bound Domain Swapped-Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F:F57H Variant of HCRBPII
分子名称: ACETATE ION, GLYCEROL, Retinol-binding protein 2, ...
著者Ghanbarpour, A, Geiger, J.
登録日2020-04-26
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Human Cellular Retinol Binding Protein II Forms a Domain-Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering.
Chembiochem, 21, 2020
6WPB
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BU of 6wpb by Molmil
NMR Structure of HSP1-NH2 antimicrobial peptide in presence of SDS-d25 micelles
分子名称: HSP1-NH2
著者Verly, R.M, Gomes, I.P.
登録日2020-04-27
公開日2020-09-02
最終更新日2020-09-16
実験手法SOLUTION NMR
主引用文献Membrane interactions of the anuran antimicrobial peptide HSP1-NH2: Different aspects of the association to anionic and zwitterionic biomimetic systems.
Biochim Biophys Acta Biomembr, 1863, 2020
6WP9
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BU of 6wp9 by Molmil
AvaR1 bound to Avenolide
分子名称: (5S)-5-[(6R)-6-hydroxy-6-methyl-5-oxooctyl]furan-2(5H)-one, AvaR1
著者Kapoor, I, Olivares, P.J, Nair, S.K.
登録日2020-04-26
公開日2020-07-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones.
Elife, 9, 2020
6WUP
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BU of 6wup by Molmil
Crystal structure of an ancestral cyclohexadienyl dehydratase, AncCDT-5
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ancestral cyclohexadienyl dehydratase, AncCDT-5, ...
著者Kaczmarski, J.A, Mahawaththa, M.C.
登録日2020-05-05
公開日2020-05-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme.
Nat Commun, 11, 2020
6WX6
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BU of 6wx6 by Molmil
Cryo-EM Structure of Human Apoferritin Light Chain Vitrified Using Back-it-up
分子名称: CALCIUM ION, Ferritin light chain
著者Tan, Y.Z, Rubinstein, J.L.
登録日2020-05-09
公開日2020-05-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献Through-grid wicking enables high-speed cryoEM specimen preparation.
Acta Crystallogr D Struct Biol, 76, 2020
6X0I
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Structure of oxidized SidA ornithine hydroxylase with the FAD "in" and complexed with NADP
分子名称: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Tanner, J.J, Campbell, A.C.
登録日2020-05-15
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
8OL1
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BU of 8ol1 by Molmil
cGAS-Nucleosome in complex with SPSB3-ELOBC (composite structure)
分子名称: Cyclic GMP-AMP synthase, DNA (145-MER), Elongin-B, ...
著者Xu, P.B, Ablasser, A.
登録日2023-03-29
公開日2024-02-14
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation.
Nature, 627, 2024
8OQ4
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AApoAII amyloid fibril Morphology II (ex vivo)
分子名称: Apolipoprotein A-II
著者Andreotti, G, Schmidt, M, Faendrich, M.
登録日2023-04-11
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Insights into the Structural Basis of Amyloid Resistance Provided by Cryo-EM Structures of AApoAII Amyloid Fibrils.
J.Mol.Biol., 436, 2024
6X59
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BU of 6x59 by Molmil
The mouse cGAS catalytic domain binding to human assembled nucleosome
分子名称: Cyclic GMP-AMP synthase, DNA, Histone H2A type 1, ...
著者Pengbiao, X, Pingwei, L, Baoyu, Z.
登録日2020-05-25
公開日2020-09-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature, 587, 2020
6X2K
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BU of 6x2k by Molmil
The Tusavirus (TuV) capsid structure
分子名称: VP2
著者Mietzsch, M, Agbandje-McKenna, M.
登録日2020-05-20
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Structural Characterization of Cuta- and Tusavirus: Insight into Protoparvoviruses Capsid Morphology.
Viruses, 12, 2020
6WED
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BU of 6wed by Molmil
Copper-bound E44Q variant of Campylobacter jejuni P19
分子名称: COPPER (II) ION, SULFATE ION, Uncharacterized protein
著者Chan, A.C, Murphy, M.E.
登録日2020-04-02
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A copper site is required for iron transport by the periplasmic proteins P19 and FetP.
Metallomics, 12, 2020
8P0W
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BU of 8p0w by Molmil
Structure of the human Commander complex COMMD ring
分子名称: COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ...
著者Kumpula, E.P, Laulumaa, S, Huiskonen, J.T.
登録日2023-05-11
公開日2024-03-20
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and interactions of the endogenous human Commander complex.
Nat.Struct.Mol.Biol., 31, 2024
6WJ5
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BU of 6wj5 by Molmil
Structure of human TRPA1 in complex with inhibitor GDC-0334
分子名称: (4R,5S)-4-fluoro-1-[(4-fluorophenyl)sulfonyl]-5-methyl-N-({5-(trifluoromethyl)-2-[2-(trifluoromethyl)pyrimidin-5-yl]pyridin-4-yl}methyl)-L-prolinamide, Transient receptor potential cation channel subfamily A member 1
著者Rohou, A, Rouge, L, Arthur, C.P, Volgraf, M, Chen, H.
登録日2020-04-11
公開日2021-02-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment.
J.Exp.Med., 218, 2021
8OM6
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BU of 8om6 by Molmil
Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2
分子名称: Fibroblast growth factor 2
著者Marek, M, Chaloupkova, R, de La Bourdonnaye, G.
登録日2023-03-31
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2
To Be Published
6X1I
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Two-Component D3 Assembly Constructed by Fusing Symmetric Oligomers to Coiled Coils
分子名称: Cob_adeno_trans domain-containing protein PH0671 fused to a coiled coil, SnoaL-like Protein fused to a coiled coil
著者Laniado, J, Yeates, T.O, Sawaya, M.R.
登録日2020-05-18
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.32 Å)
主引用文献Geometric Lessons and Design Strategies for Nanoscale Protein Cages.
Acs Nano, 15, 2021
8P1R
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BU of 8p1r by Molmil
Bifidobacterium asteroides alpha-L-fucosidase (TT1819) catalytic mutant.
分子名称: 1,2-ETHANEDIOL, Bifidobacterium asteroides alpha-L-fucosidase (TT1819) catalytic mutant, MAGNESIUM ION
著者Owen, C.D, Penner, M, Gascuena, A.N, Wu, H, Hernando, P.J, Monaco, S, Le Gall, G, Gardner, R, Ndeh, D, Urbanowicz, P.A, Spencer, D.I.R, Walsh, M.A, Angulo, J, Juge, N.
登録日2023-05-12
公開日2024-03-27
実験手法X-RAY DIFFRACTION (1.659 Å)
主引用文献Exploring sequence, structure and function of microbial fucosidases from glycoside hydrolase GH29 family
To Be Published

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件を2024-08-14に公開中

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