PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

---

3WK3	Orotidine 5'-monophosphate decarboxylase K72A mutant from M. thermoautotrophicus complexed with orotidine 5'-monophosphate ethyl ester 分子名称: 6-(ethoxycarbonyl)uridine 5'-(dihydrogen phosphate), GLYCEROL, Orotidine 5'-phosphate decarboxylase 著者 Fujihashi, M, Pai, E.F, Miki, K. 登録日 2013-10-17 公開日 2013-12-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Substrate distortion contributes to the catalysis of orotidine 5'-monophosphate decarboxylase. J.Am.Chem.Soc., 135, 2013
3W3K	Crystal structure of human TLR8 in complex with CL075 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-propyl[1,3]thiazolo[4,5-c]quinolin-4-amine, ... 著者 Tanji, H, Ohto, U, Shimizu, T. 登録日 2012-12-22 公開日 2013-04-03 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands Science, 339, 2013
3WF3	Crystal structure of human beta-galactosidase mutant I51T in complex with Galactose 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase, ... 著者 Suzuki, H, Ohto, U, Shimizu, T. 登録日 2013-07-16 公開日 2014-04-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural basis of pharmacological chaperoning for human beta-galactosidase to be published
3WCO	Crystal structure of the depentamerized mutant of N-terminal truncated selenocysteine synthase SelA 分子名称: L-seryl-tRNA(Sec) selenium transferase, THIOSULFATE 著者 Itoh, Y, Sekine, S, Yokoyama, S. 登録日 2013-05-29 公開日 2014-01-22 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Dimer-Dimer Interaction of the Bacterial Selenocysteine Synthase SelA Promotes Functional Active-Site Formation and Catalytic Specificity J.Mol.Biol., 426, 2014
3WK0	Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with orotidine 5'-monophosphate methyl ester 分子名称: 6-(methoxycarbonyl)uridine 5'-(dihydrogen phosphate), GLYCEROL, Orotidine 5'-phosphate decarboxylase 著者 Fujihashi, M, Pai, E.F, Miki, K. 登録日 2013-10-17 公開日 2013-12-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Substrate distortion contributes to the catalysis of orotidine 5'-monophosphate decarboxylase. J.Am.Chem.Soc., 135, 2013
3W3N	Crystal structure of human TLR8 in complex with Resiquimod (R848) crystal form 3 分子名称: 1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Tanji, H, Ohto, U, Shimizu, T. 登録日 2012-12-22 公開日 2013-04-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands Science, 339, 2013
3W9G	Crystal structure of the ankyrin repeat domain of chicken TRPV4 分子名称: Vanilloid receptor-related osmotically activated channel protein 著者 Itoh, Y, Hamada-nakahara, S, Suetsugu, S. 登録日 2013-04-04 公開日 2014-04-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P2 Nat Commun, 5, 2014
3WAX	Crystal Structure of Autotaxin in Complex with 3BoA 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2013-05-09 公開日 2013-07-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.899 Å) 主引用文献 Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
3WAY	Crystal Structure of Autotaxin in Complex with 4BoA 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2013-05-09 公開日 2013-07-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.746 Å) 主引用文献 Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
3WF2	Crystal structure of human beta-galactosidase in complex with NBT-DGJ 分子名称: (2R,3S,4R,5S)-N-butyl-3,4,5-trihydroxy-2-(hydroxymethyl)piperidine-1-carbothioamide, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Suzuki, H, Ohto, U, Shimizu, T. 登録日 2013-07-16 公開日 2014-04-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of pharmacological chaperoning for human beta-galactosidase to be published
3WAV	Crystal Structure of Autotaxin in Complex with Compound 10 分子名称: (5Z)-5-(3,4-dichlorobenzylidene)-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2013-05-09 公開日 2013-07-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.797 Å) 主引用文献 Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
3WF0	Crystal structure of human beta-galactosidase in complex with 6S-NBI-DGJ 分子名称: (3Z,6S,7R,8S,8aS)-3-(butylimino)hexahydro[1,3]thiazolo[3,4-a]pyridine-6,7,8-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Suzuki, H, Ohto, U, Shimizu, T. 登録日 2013-07-16 公開日 2014-04-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of pharmacological chaperoning for human beta-galactosidase to be published
3WK2	Orotidine 5'-monophosphate decarboxylase K72A mutant from M. thermoautotrophicus complexed with orotidine 5'-monophosphate methyl ester 分子名称: 6-(methoxycarbonyl)uridine 5'-(dihydrogen phosphate), GLYCEROL, Orotidine 5'-phosphate decarboxylase 著者 Fujihashi, M, Pai, E.F, Miki, K. 登録日 2013-10-17 公開日 2013-12-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Substrate distortion contributes to the catalysis of orotidine 5'-monophosphate decarboxylase. J.Am.Chem.Soc., 135, 2013
3WPH	Crystal structure of mouse TLR9 in complex with inhibitory DNA4084 (form 2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-D(*CP*CP*TP*GP*GP*AP*TP*GP*GP*GP*AP*A)-3'), SULFATE ION, ... 著者 Ohto, U, Shimizu, T. 登録日 2014-01-11 公開日 2015-02-11 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.327 Å) 主引用文献 Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9 Nature, 520, 2015
3WVG	Time-Resolved Crystal Structure of HindIII with 0sec soaking 分子名称: DNA (5'-D(*GP*CP*CP*AP*AP*GP*CP*TP*TP*GP*GP*C)-3'), GLYCEROL, SODIUM ION, ... 著者 Kawamura, T, Kobayashi, T, Watanabe, N. 登録日 2014-05-21 公開日 2015-04-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Analysis of the HindIII-catalyzed reaction by time-resolved crystallography Acta Crystallogr.,Sect.D, 71, 2015
3WQP	Crystal structure of Rubisco T289D mutant from Thermococcus kodakarensis 分子名称: 1,2-ETHANEDIOL, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Fujihashi, M, Nishitani, Y, Kiriyama, T, Miki, K. 登録日 2014-01-29 公開日 2015-02-04 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Mutation design of thermophilic Rubisco based on the three-dimensional structure enhances its activity at ambient temperature to be published
3WVK	Time-Resolved Crystal Structure of HindIII with 230sec soaking 分子名称: DNA (5'-D(*GP*CP*CP*A)-3'), DNA (5'-D(*GP*CP*CP*AP*AP*GP*CP*TP*TP*GP*GP*C)-3'), DNA (5'-D(P*AP*GP*CP*TP*TP*GP*GP*C)-3'), ... 著者 Kawamura, T, Kobayashi, T, Watanabe, N. 登録日 2014-05-22 公開日 2015-04-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Analysis of the HindIII-catalyzed reaction by time-resolved crystallography Acta Crystallogr.,Sect.D, 71, 2015
3X1U	Crystal structure of nucleosome core particle in the presence of histone variants involved in reprogramming 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A, ... 著者 Sivaraman, P, Kumarevel, T.S. 登録日 2014-11-28 公開日 2015-09-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming. Biochem.Biophys.Res.Commun., 464, 2015
4OO9	Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator mavoglurant 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mavoglurant, Metabotropic glutamate receptor 5, ... 著者 Dore, A.S, Okrasa, K, Patel, J.C, Serrano-Vega, M, Bennett, K, Cooke, R.M, Errey, J.C, Jazayeri, A, Khan, S, Tehan, B, Weir, M, Wiggin, G.R, Marshall, F.H. 登録日 2014-01-31 公開日 2014-07-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain. Nature, 511, 2014
4OU3	Crystal structure of porcine aminopeptidase N complexed with CNGRCG tumor-homing peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... 著者 Liu, C, Yang, Y, Chen, L, Lin, Y.-L, Li, F. 登録日 2014-02-14 公開日 2014-11-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A Unified Mechanism for Aminopeptidase N-based Tumor Cell Motility and Tumor-homing Therapy. J.Biol.Chem., 289, 2014
3UGP	Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TATAAT) 分子名称: 5'-D(*TP*GP*TP*AP*TP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor 著者 Feklistov, A, Darst, S.A. 登録日 2011-11-02 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.697 Å) 主引用文献 Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit. Cell(Cambridge,Mass.), 147, 2011
3UCK	Coccomyxa beta-carbonic anhydrase in complex with phosphate 分子名称: CHLORIDE ION, Carbonic anhydrase, PHOSPHATE ION, ... 著者 Huang, S, Hainzl, T, Sauer-Eriksson, A.E. 登録日 2011-10-27 公開日 2011-11-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural studies of [beta]-carbonic anhydrase from the green alga Coccomyxa: inhibitor complexes with anions and acetazolamide. Plos One, 6, 2011
4OON	Crystal structure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) 分子名称: (4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid, Penicillin-binding protein 1A 著者 Han, S, Caspers, N, Knafels, J.D. 登録日 2014-02-03 公開日 2014-05-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. J.Med.Chem., 57, 2014
3UGU	Crystal Structure of p44 (Splice Variant of Visual Arrestin) 分子名称: S-arrestin 著者 Batra-Safferling, R, Granzin, J. 登録日 2011-11-03 公開日 2012-02-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structure of p44, a Constitutively Active Splice Variant of Visual Arrestin. J.Mol.Biol., 416, 2012
4OV2	Crystal structure of C-terminally truncated Neuronal Calcium Sensor (NCS-1) from Rattus norvegicus 分子名称: CALCIUM ION, Neuronal calcium sensor 1 著者 Pandaleneni, S, Burgoyne, R, Mayans, O, Lian, L.-Y. 登録日 2014-02-19 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of C-terminally truncated Neuronal Calcium Sensor (NCS-1) from Rattus norvegicus To be Published

<725726727728729730731732733734735736737738739740>