3QNX
 
 | | Orthorhombic form of human IgA1 Fab fragment, sharing same Fv as IgG | | 分子名称: | Fab fragment of IMMUNOGLOBULIN A1 HEAVY CHAIN, Fab fragment of IMMUNOGLOBULIN A1 LIGHT CHAIN, GLYCEROL | | 著者 | Trajtenberg, F, Correa, A, Buschiazzo, A. | | 登録日 | 2011-02-09 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a human IgA1 Fab fragment at 1.55 angstrom resolution: potential effect of the constant domains on antigen-affinity modulation
Acta Crystallogr.,Sect.D, 69, 2013
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3INU
 | | Crystal structure of an unbound KZ52 neutralizing anti-Ebolavirus antibody. | | 分子名称: | GLYCEROL, KZ52 antibody fragment heavy chain, KZ52 antibody fragment light chain, ... | | 著者 | Lee, J.E, Fusco, M.L, Abelson, D.M, Hessell, A.J, Burton, D.R, Saphire, E.O. | | 登録日 | 2009-08-12 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Techniques and tactics used in determining the structure of the trimeric ebolavirus glycoprotein.
Acta Crystallogr.,Sect.D, 65, 2009
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3IOK
 | | 2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2 | | 分子名称: | 3-(6-{[(1S)-1-(4-fluorophenyl)ethyl]amino}pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine, Tyrosine-protein kinase JAK2 | | 著者 | Zuccola, H.J, Ledeboer, M.W, Pierce, A.C. | | 登録日 | 2009-08-14 | | 公開日 | 2009-11-10 | | 最終更新日 | 2013-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | 2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2.
Bioorg.Med.Chem.Lett., 19, 2009
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3QPG
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3QLS
 | | Candida albicans dihydrofolate reductase complexed with NADPH and 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP115A) | | 分子名称: | 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine, GLYCEROL, GLYCINE, ... | | 著者 | Paulsen, J.L, Bendel, S.D, Anderson, A.C. | | 登録日 | 2011-02-03 | | 公開日 | 2011-07-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.733 Å) | | 主引用文献 | Crystal Structures of Candida albicans Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal the Flexibility of Active Site Loop Residues Critical for Ligand Potency and Selectivity.
Chem.Biol.Drug Des., 78, 2011
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3ITA
 | | Crystal structure of Penicillin-Binding Protein 6 (PBP6) from E. coli in acyl-enzyme complex with ampicillin | | 分子名称: | (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, D-alanyl-D-alanine carboxypeptidase dacC, ... | | 著者 | Chen, Y, Zhang, W, Shi, Q, Hesek, D, Lee, M, Mobashery, S, Shoichet, B.K. | | 登録日 | 2009-08-27 | | 公開日 | 2009-10-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of penicillin-binding protein 6 from Escherichia coli.
J.Am.Chem.Soc., 131, 2009
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3QQ7
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3ITQ
 | | Crystal Structure of a Prolyl 4-Hydroxylase from Bacillus anthracis | | 分子名称: | GLYCEROL, PHOSPHATE ION, Prolyl 4-hydroxylase, ... | | 著者 | Culpepper, M.A, Scott, E.E, Limburg, J. | | 登録日 | 2009-08-28 | | 公開日 | 2009-12-15 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of prolyl 4-hydroxylase from Bacillus anthracis.
Biochemistry, 49, 2010
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3QQ0
 | | Crystal structure of a deletion mutant (N59) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis | | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, GLYCEROL, ... | | 著者 | Allison, T.M, Jameson, G.B, Parker, E.J. | | 登録日 | 2011-02-14 | | 公開日 | 2011-04-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase
Biochemistry, 50, 2011
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3IJM
 | | The structure of a restriction endonuclease-like fold superfamily protein from Spirosoma linguale. | | 分子名称: | GLYCEROL, SODIUM ION, SULFATE ION, ... | | 著者 | Cuff, M.E, Tesar, C, Samano, S, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2009-08-04 | | 公開日 | 2009-09-22 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The structure of a restriction endonuclease-like fold superfamily protein from Spirosoma linguale.
TO BE PUBLISHED
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3I71
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3QQM
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3I76
 | | The crystal structure of the orthorhombic form of the putative HAD-hydrolase YfnB from Bacillus subtilis bound to magnesium reveals interdomain movement | | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Bonanno, J.B, Dickey, M, Bain, K.T, Tang, B.K, Romero, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2009-07-08 | | 公開日 | 2009-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of the orthorhombic form of the putative HAD-hydrolase YfnB from Bacillus subtilis bound to magnesium reveals interdomain movement
To be Published
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3RTA
 | | Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with Acetyl Coenzyme A | | 分子名称: | ACETYL COENZYME *A, POTASSIUM ION, Putative uncharacterized protein, ... | | 著者 | Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W. | | 登録日 | 2011-05-03 | | 公開日 | 2011-06-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012
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3IMK
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3R0H
 | | Structure of INAD PDZ45 in complex with NG2 peptide | | 分子名称: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Inactivation-no-after-potential D protein, ... | | 著者 | Wei, Z, Liu, W, Zhang, M. | | 登録日 | 2011-03-08 | | 公開日 | 2011-11-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye
Cell(Cambridge,Mass.), 145, 2011
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3I9I
 | | Crystal structure of human transthyretin variant A25T - #2 | | 分子名称: | TRIETHYLENE GLYCOL, Transthyretin | | 著者 | Palmieri, L.C, Freire, J.B.B, Palhano, F.L, Azevedo, E.P.C, Foguel, D, Lima, L.M.T.R. | | 登録日 | 2009-07-11 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of human transthyretin variant A25T - #2
To be Published
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3R7F
 | | Crystal Structure of CP-bound Aspartate Transcarbamoylase from Bacillus subtilis | | 分子名称: | Aspartate carbamoyltransferase, PHOSPHATE ION, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER | | 著者 | Cockrell, G.M, Harris, K.M, Puleo, D.E, Kantrowitz, E.R. | | 登録日 | 2011-03-22 | | 公開日 | 2011-06-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Crystallographic Snapshots of the Complete Catalytic Cycle of the Unregulated Aspartate Transcarbamoylase from Bacillus subtilis.
J.Mol.Biol., 411, 2011
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3INA
 | | Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin | | 分子名称: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, CALCIUM ION, Heparin lyase I | | 著者 | Han, Y.H, Ryu, K.S, Kim, H.Y, Jeon, Y.H. | | 登録日 | 2009-08-12 | | 公開日 | 2009-09-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural snapshots of heparin depolymerization by heparin lyase I
J.Biol.Chem., 284, 2009
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3INL
 | | Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with agonist Alda-1 | | 分子名称: | 1,2-ETHANEDIOL, Aldehyde dehydrogenase, mitochondrial, ... | | 著者 | Perez-Miller, S, Hurley, T.D. | | 登録日 | 2009-08-12 | | 公開日 | 2010-01-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.862 Å) | | 主引用文献 | Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant.
Nat.Struct.Mol.Biol., 17, 2010
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3IAE
 | | Structure of benzaldehyde lyase A28S mutant with benzoylphosphonate | | 分子名称: | 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, Benzaldehyde lyase, CALCIUM ION | | 著者 | Brandt, G.S, Petsko, G.A, Ringe, D, McLeish, M.J. | | 登録日 | 2009-07-13 | | 公開日 | 2010-03-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Active-site engineering of benzaldehyde lyase shows that a point mutation can confer both new reactivity and susceptibility to mechanism-based inhibition.
J.Am.Chem.Soc., 132, 2010
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3R8E
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3R3W
 | | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Chloroacetate | | 分子名称: | CALCIUM ION, CHLORIDE ION, Fluoroacetate dehalogenase, ... | | 著者 | Chan, P.W.Y, Yakunin, A.F, Edwards, E.A, Pai, E.F. | | 登録日 | 2011-03-16 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Mapping the reaction coordinates of enzymatic defluorination.
J.Am.Chem.Soc., 133, 2011
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3R46
 | | Crystal structure of a parallel 6-helix coiled coil CC-hex-D24 | | 分子名称: | CHLORIDE ION, GLYCEROL, SODIUM ION, ... | | 著者 | Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L. | | 登録日 | 2011-03-17 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | | 主引用文献 | A de novo peptide hexamer with a mutable channel.
Nat.Chem.Biol., 7, 2011
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3IB7
 | | Crystal structure of full length Rv0805 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | | 著者 | Podobnik, M, Dermol, U. | | 登録日 | 2009-07-15 | | 公開日 | 2009-09-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A mycobacterial cyclic AMP phosphodiesterase that moonlights as a modifier of cell wall permeability
J.Biol.Chem., 284, 2009
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