3IAE

Structure of benzaldehyde lyase A28S mutant with benzoylphosphonate

Summary for 3IAE

Entry DOI	10.2210/pdb3iae/pdb
Related	3IAF
Descriptor	Benzaldehyde lyase, 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, CALCIUM ION, ... (4 entities in total)
Functional Keywords	thiamine adduct, lyase
Biological source	Pseudomonas fluorescens
Total number of polymer chains	2
Total formula weight	121119.15
Authors	Brandt, G.S.,Petsko, G.A.,Ringe, D.,McLeish, M.J. (deposition date: 2009-07-13, release date: 2010-03-02, Last modification date: 2023-09-06)
Primary citation	Brandt, G.S.,Kneen, M.M.,Petsko, G.A.,Ringe, D.,McLeish, M.J. Active-site engineering of benzaldehyde lyase shows that a point mutation can confer both new reactivity and susceptibility to mechanism-based inhibition. J.Am.Chem.Soc., 132:438-439, 2010 Cited by PubMed: 20030408 DOI: 10.1021/ja907064w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation