8AXR
 
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8AXO
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7RFK
 | | CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Inhibitor Sinefungin | | 分子名称: | 1,2-ETHANEDIOL, DNA Strand 1, DNA Strand 2, ... | | 著者 | Horton, J.R, Cheng, X, Zhou, J. | | 登録日 | 2021-07-14 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Repurposing epigenetic inhibitors to target the Clostridioides difficile- specific DNA adenine methyltransferase and sporulation regulator CamA.
Epigenetics, 17, 2022
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7RFL
 | | CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Inhibitor SGC0946 | | 分子名称: | 1,2-ETHANEDIOL, 5-bromo-7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, DNA Strand 1, ... | | 著者 | Horton, J.R, Cheng, X, Zhou, J. | | 登録日 | 2021-07-14 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Repurposing epigenetic inhibitors to target the Clostridioides difficile- specific DNA adenine methyltransferase and sporulation regulator CamA.
Epigenetics, 17, 2022
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7RFM
 | | CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Inhibitor EPZ004777 | | 分子名称: | 1,2-ETHANEDIOL, 7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, DNA Strand 1, ... | | 著者 | Horton, J.R, Cheng, X, Zhou, J. | | 登録日 | 2021-07-14 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Repurposing epigenetic inhibitors to target the Clostridioides difficile- specific DNA adenine methyltransferase and sporulation regulator CamA.
Epigenetics, 17, 2022
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7RAH
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8B1S
 | | co-crystal of SUDV VP40 with salicylic acid | | 分子名称: | 2-HYDROXYBENZOIC ACID, Matrix protein VP40 | | 著者 | Werner, A.-D, Krapoth, N, Norris, M.J, Heine, A, Klebe, G, Ollmann Saphire, E, Becker, S. | | 登録日 | 2022-09-12 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Development of a Crystallographic Screening to Identify Sudan Virus VP40 Ligands.
Acs Omega, 9, 2024
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7RFN
 | | CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Inhibitor SGC8158 | | 分子名称: | 1,2-ETHANEDIOL, 5'-S-(4-{[(4'-chloro[1,1'-biphenyl]-3-yl)methyl]amino}butyl)-5'-thioadenosine, DNA Strand 1, ... | | 著者 | Horton, J.R, Cheng, X, Zhou, J. | | 登録日 | 2021-07-14 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Repurposing epigenetic inhibitors to target the Clostridioides difficile- specific DNA adenine methyltransferase and sporulation regulator CamA.
Epigenetics, 17, 2022
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8ANT
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8ANV
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8EBO
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1DGZ
 | | RIBOSMAL PROTEIN L36 FROM THERMUS THERMOPHILUS: NMR STRUCTURE ENSEMBLE | | 分子名称: | PROTEIN (L36 RIBOSOMAL PROTEIN), ZINC ION | | 著者 | Hard, T, Rak, A, Allard, P, Kloo, L, Garber, M. | | 登録日 | 1999-11-27 | | 公開日 | 1999-12-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of ribosomal protein L36 from Thermus thermophilus reveals a zinc-ribbon-like fold.
J.Mol.Biol., 296, 2000
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8E9F
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8QRF
 | | SARS-CoV-2 delta RBD complexed with XBB-6 and beta-49 Fabs | | 分子名称: | Beta-49 heavy chain, Beta-49 light chain, Spike protein S1, ... | | 著者 | Zhou, D, Ren, J, Stuart, D.I. | | 登録日 | 2023-10-06 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity.
Cell Rep Med, 5, 2024
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8B22
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8DQP
 | | Crystal structure of Arabidopsis thaliana COSY in complex with scopoletin | | 分子名称: | 1,2-ETHANEDIOL, 7-hydroxy-6-methoxy-2H-1-benzopyran-2-one, ACETATE ION, ... | | 著者 | Kim, C.Y, Mitchell, A.J, Gutierrez, M, Weng, J.K. | | 登録日 | 2022-07-19 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Emergence of a proton exchange-based isomerization and lactonization mechanism in the plant coumarin synthase COSY.
Nat Commun, 14, 2023
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8B23
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8B21
 | | Time-resolved structure of K+-dependent Na+-PPase from Thermotoga maritima 0-60-seconds post reaction initiation with Na+ | | 分子名称: | DI(HYDROXYETHYL)ETHER, DODECYL-BETA-D-MALTOSIDE, K(+)-stimulated pyrophosphate-energized sodium pump, ... | | 著者 | Strauss, J, Vidilaseris, K, Goldman, A. | | 登録日 | 2022-09-12 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases.
Embo Rep., 25, 2024
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8DV6
 | | Zika virus envelope protein structure in complex with a potent Human mAb | | 分子名称: | Envelope protein E, mAb Fab Heavy Chain, mAb Fab Light Chain | | 著者 | Cameron, A, Puhl, A.C, deSilva, A.M, Premkumar, L. | | 登録日 | 2022-07-28 | | 公開日 | 2023-01-04 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | | 主引用文献 | Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus.
Plos Pathog., 19, 2023
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8GNA
 | | Structure of the SbCas7-11-crRNA-NTR complex | | 分子名称: | RAMP superfamily protein, RNA (32-MER), RNA (5'-R(P*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*GP*U)-3'), ... | | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | | 登録日 | 2022-08-23 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Target RNA-guided protease activity in type III-E CRISPR-Cas system.
Nucleic Acids Res., 50, 2022
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8GU6
 | | Structure of the SbCas7-11-crRNA-NTR-Csx29 complex | | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | | 登録日 | 2022-09-10 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Target RNA-guided protease activity in type III-E CRISPR-Cas system.
Nucleic Acids Res., 50, 2022
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8DQQ
 | | Crystal structure of Arabidopsis thaliana COSY in complex with scopoletin | | 分子名称: | 7-hydroxy-2H-chromen-2-one, ACETATE ION, CALCIUM ION, ... | | 著者 | Kim, C.Y, Mitchell, A.J, Gutierrez, M, Weng, J.K. | | 登録日 | 2022-07-19 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Emergence of a proton exchange-based isomerization and lactonization mechanism in the plant coumarin synthase COSY.
Nat Commun, 14, 2023
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8B24
 | | Time-resolved structure of K+-dependent Na+-PPase from Thermotoga maritima 3600-seconds post reaction initiation with Na+ | | 分子名称: | DIPHOSPHATE, K(+)-stimulated pyrophosphate-energized sodium pump, MAGNESIUM ION, ... | | 著者 | Strauss, J, Vidilaseris, K, Goldman, A. | | 登録日 | 2022-09-12 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (4.53 Å) | | 主引用文献 | Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases.
Embo Rep., 25, 2024
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7R96
 | | Self-Assembled 3D DNA Hexagonal Tensegrity Triangle | | 分子名称: | DNA (5'-D(*AP*GP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*CP*CP*GP*TP*AP*CP*A)-3'), ... | | 著者 | Lu, B, Vecchioni, S, Ohayon, Y.P, Sha, R, Mao, C, Seeman, N.C. | | 登録日 | 2021-06-28 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (5.68 Å) | | 主引用文献 | 3D Hexagonal Arrangement of DNA Tensegrity Triangles.
Acs Nano, 15, 2021
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8EAZ
 | | HOIL-1/E2-Ub/Ub transthiolation complex | | 分子名称: | RanBP-type and C3HC4-type zinc finger-containing protein 1, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... | | 著者 | Wang, X.S, Cotton, T.R, Lechtenberg, B.C. | | 登録日 | 2022-08-30 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | | 主引用文献 | The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family.
Nat Commun, 14, 2023
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