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3D5O
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Structural recognition and functional activation of FcrR by innate pentraxins
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Low affinity immunoglobulin gamma Fc region receptor II-a, ...
著者Lu, J, Marnell, L.L, Marjon, K.D, Mold, C, Du Clos, T.W, Sun, P.D.
登録日2008-05-16
公開日2008-11-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural recognition and functional activation of FcgammaR by innate pentraxins.
Nature, 456, 2008
4FP1
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P. putida mandelate racemase co-crystallized with 3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl) propionic acid
分子名称: 3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propanoic acid, MAGNESIUM ION, Mandelate racemase
著者Lietzan, A.D, St.Maurice, M.
登録日2012-06-21
公開日2013-06-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Potent inhibition of mandelate racemase by a fluorinated substrate-product analogue with a novel binding mode.
Biochemistry, 53, 2014
3D5X
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Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with wortmannin.
分子名称: (1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4, 3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE, Polo-like kinase 1
著者Elling, R.A, Fucini, R.V, Romanowski, M.J.
登録日2008-05-17
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of the wild-type and activated catalytic domains of Brachydanio rerio Polo-like kinase 1 (Plk1): changes in the active-site conformation and interactions with ligands.
Acta Crystallogr.,Sect.D, 64, 2008
4FMO
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BU of 4fmo by Molmil
Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer bound to a fragment of exo1
分子名称: DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, DNA repair peptide, ...
著者Gueneau, E, Legrand, P, Charbonnier, J.B.
登録日2012-06-18
公開日2013-02-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Nat.Struct.Mol.Biol., 20, 2013
3D68
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Crystal structure of a T325I/T329I/H333Y/H335Q mutant of Thrombin-Activatable Fibrinolysis Inhibitor (TAFI-IIYQ)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ARGININE, Carboxypeptidase B2, ...
著者Brondijk, T.H.C, Huizinga, E.G.
登録日2008-05-19
公開日2008-07-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood, 112, 2008
3D72
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1.65 Angstrom crystal structure of the Cys71Val variant in the fungal photoreceptor VVD
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Vivid PAS protein VVD
著者Zoltowski, B.D, Crane, B.R.
登録日2008-05-20
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Light activation of the LOV protein vivid generates a rapidly exchanging dimer.
Biochemistry, 47, 2008
3D3Y
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Crystal structure of a conserved protein from Enterococcus faecalis V583
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Uncharacterized protein
著者Tan, K, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-05-13
公開日2008-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The crystal structure of a conserved protein from Enterococcus faecalis V583.
To be Published
3D7K
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Crystal structure of benzaldehyde lyase in complex with the inhibitor MBP
分子名称: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, Benzaldehyde lyase, CALCIUM ION
著者Brandt, G.S.
登録日2008-05-21
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Probing the active center of benzaldehyde lyase with substitutions and the pseudosubstrate analogue benzoylphosphonic acid methyl ester
Biochemistry, 47, 2008
4FQA
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Crystal structure of toxic effector Tse1
分子名称: toxic effector Tse1
著者Li, L, Zhang, W, Wang, T.
登録日2012-06-25
公開日2013-06-26
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insight on toxic effector Tse1
To be Published
3VNP
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Crystal structure of hypothetical protein (GK2848) from Geobacillus Kaustophilus
分子名称: ACETIC ACID, Hypothetical conserved protein, MAGNESIUM ION
著者Karthe, P.P, Kumarevel, T.S, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2012-01-17
公開日2012-03-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of hypothetical protein (GK2848) from Geobacillus Kaustophilus
To be Published
4FNI
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Crystal structure of IsdI-W66Y in complex with heme and cyanide
分子名称: CYANIDE ION, Heme-degrading monooxygenase isdI, MAGNESIUM ION, ...
著者Ukpabi, G.N, Murphy, M.E.P.
登録日2012-06-19
公開日2012-08-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Inactivation of the heme degrading enzyme IsdI by an active site substitution that diminishes heme ruffling.
J.Biol.Chem., 287, 2012
4FNS
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Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin
分子名称: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, Alpha-galactosidase AgaA, ...
著者Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P.
登録日2012-06-20
公開日2012-10-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies
J.Biol.Chem., 287, 2012
3D59
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Crystal structure of human plasma platelet activating factor acetylhydrolase
分子名称: ACETATE ION, Platelet-activating factor acetylhydrolase, SULFATE ION
著者Samanta, U, Bahnson, B.J.
登録日2008-05-16
公開日2008-09-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Human Plasma Platelet-activating Factor Acetylhydrolase: STRUCTURAL IMPLICATION TO LIPOPROTEIN BINDING AND CATALYSIS.
J.Biol.Chem., 283, 2008
3CEZ
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BU of 3cez by Molmil
Crystal structure of methionine-R-sulfoxide reductase from Burkholderia pseudomallei
分子名称: ACETIC ACID, Methionine-R-sulfoxide reductase, ZINC ION
著者Staker, B, Napuli, A, Nakazawa, S.H, Castaneda, L, Alkafeef, S, Vanvoorhis, W, Stewart, L, Myler, P, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2008-02-29
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Methionine-R-sulfoxide reductase from Burkholderia pseudomallei.
To be Published
4FQU
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BU of 4fqu by Molmil
Glutathionyl-Hydroquinone Reductase PcpF of Sphingobium chlorophenolicum
分子名称: Putative glutathione transferase
著者Green, A.R, Hayes, R.P, Xun, L, Kang, C.
登録日2012-06-25
公開日2012-09-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural understanding of the glutathione-dependent reduction mechanism of glutathionyl-hydroquinone reductases.
J.Biol.Chem., 287, 2012
3D6J
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Crystal structure of Putative haloacid dehalogenase-like hydrolase from Bacteroides fragilis
分子名称: GLYCEROL, PHOSPHATE ION, Putative haloacid dehalogenase-like hydrolase
著者Chang, C, Wu, R, Cobb, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-05-19
公開日2008-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Putative haloacid dehalogenase-like hydrolase from Bacteroides fragilis
To be Published
4FP8
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Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin, HA1 subunit
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05, ...
著者Ekiert, D.C, Wilson, I.A.
登録日2012-06-21
公開日2012-09-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.947 Å)
主引用文献Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Nature, 489, 2012
3D6N
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Crystal Structure of Aquifex Dihydroorotase Activated by Aspartate Transcarbamoylase
分子名称: Aspartate carbamoyltransferase, CITRATE ANION, Dihydroorotase, ...
著者Edwards, B.F.P.
登録日2008-05-20
公開日2009-01-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dihydroorotase from the hyperthermophile Aquifiex aeolicus is activated by stoichiometric association with aspartate transcarbamoylase and forms a one-pot reactor for pyrimidine biosynthesis.
Biochemistry, 48, 2009
4FR0
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BU of 4fr0 by Molmil
ArsM arsenic(III) S-adenosylmethionine methyltransferase with SAM
分子名称: Arsenic methyltransferase, S-ADENOSYLMETHIONINE
著者Ajees, A.A, Marapakala, K, Packianathan, C, Sankaran, B, Rosen, B.P.
登録日2012-06-26
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of an As(III) S-Adenosylmethionine Methyltransferase: Insights into the Mechanism of Arsenic Biotransformation.
Biochemistry, 51, 2012
4FHI
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Development of synthetically accessible non-secosteroidal hybrid molecules combining vitamin D receptor agonism and histone deacetylase inhibition
分子名称: N-hydroxy-2-{4-[3-(4-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-3-methylphenyl)pentan-3-yl]-2-methylphenoxy}acetamide, SRC-1, Vitamin Nuclear Receptor
著者Fischer, J, Wang, T.T, Kaldre, D, Rochel, N, Moras, D, White, J.H, Gleason, J.L.
登録日2012-06-06
公開日2012-09-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Synthetically accessible non-secosteroidal hybrid molecules combining vitamin d receptor agonism and histone deacetylase inhibition.
Chem.Biol., 19, 2012
3CFE
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BU of 3cfe by Molmil
Crystal structure of purple-fluorescent antibody EP2-25C10
分子名称: GLYCEROL, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-IGG2B HEAVY CHAIN, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-KAPPA LIGHT CHAIN, ...
著者Debler, E.W, Heine, A, Wilson, I.A.
登録日2008-03-03
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3D75
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Crystal structure of a pheromone binding protein mutant D35N, from Apis mellifera, at pH 5.5
分子名称: N-BUTYL-BENZENESULFONAMIDE, Pheromone-binding protein ASP1
著者Pesenti, M.E, Spinelli, S, Bezirard, V, Briand, L, Pernollet, J.C, Tegoni, M, Cambillau, C.
登録日2008-05-20
公開日2009-05-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Queen bee pheromone binding protein pH-induced domain swapping favors pheromone release
J.Mol.Biol., 390, 2009
4FHP
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Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - CaUTP bound
分子名称: CALCIUM ION, GLYCEROL, Poly(A) RNA polymerase protein cid1, ...
著者Lunde, B.M, Magler, I, Meinhart, A.
登録日2012-06-06
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity.
Nucleic Acids Res., 40, 2012
3CFP
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Structure of the replicating complex of a POL Alpha family DNA Polymerase, ternary complex 1
分子名称: CALCIUM ION, CHLORIDE ION, DNA (5'-D(*DAP*DCP*DAP*DGP*DGP*DTP*DAP*DAP*DGP*DCP*DAP*DGP*DTP*DCP*DCP*DGP*DCP*DG)-3'), ...
著者Wang, J, Klimenko, D, Wang, M, Steitz, T.A, Konigsberg, W.H.
登録日2008-03-04
公開日2009-03-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insights into base selectivity from the structures of an RB69 DNA Polymerase triple mutant
To be Published
3CGE
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Pyridine Nucleotide Complexes with Bacillus anthracis Coenzyme A-Disulfide Reductase: A Structural Analysis of Dual NAD(P)H Specificity
分子名称: COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Wallen, J.R.
登録日2008-03-05
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.262 Å)
主引用文献Pyridine Nucleotide Complexes with Bacillus anthracis Coenzyme A-Disulfide Reductase: A Structural Analysis of Dual NAD(P)H Specificity.
Biochemistry, 47, 2008

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