3CUO
 
 | | Crystal structure of the predicted DNA-binding transcriptional regulator from E. coli | | 分子名称: | Uncharacterized HTH-type transcriptional regulator ygaV | | 著者 | Zhang, R, Evdokimova, E, Kagan, O, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-04-16 | | 公開日 | 2008-06-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of the predicted DNA-binding transcriptional regulator from E. coli.
To be Published
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4FID
 | | Crystal structure of a heterotrimeric G-Protein subunit from entamoeba histolytica, EHG-ALPHA-1 | | 分子名称: | G protein alpha subunit, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Bosch, D.E, Kimple, A.J, Muller, R.E, Gigure, P.M, Willard, F.S, Machius, M, Temple, B.R, Siderovski, D.P. | | 登録日 | 2012-06-08 | | 公開日 | 2012-11-28 | | 最終更新日 | 2013-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Heterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica.
Plos Pathog., 8, 2012
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4FF8
 | | Inhibitor bound structure of the kinase domain of the murine receptor tyrosine kinase TYRO3 (Sky) | | 分子名称: | 4-(cyclopentylamino)-2-[(2-methoxybenzyl)amino]-N-[3-(2-oxopyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide, Tyrosine-protein kinase receptor TYRO3 | | 著者 | Ohren, J.F, Powell, N.A, Kohrt, J, Perrin, L.A. | | 登録日 | 2012-05-31 | | 公開日 | 2013-03-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase.
Bioorg.Med.Chem.Lett., 23, 2013
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3CUX
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4FJ2
 | | Crystal structure of the ternary complex between a fungal 17beta-hydroxysteroid dehydrogenase (Holo form) and biochanin A | | 分子名称: | 1,2-ETHANEDIOL, 17beta-hydroxysteroid dehydrogenase, 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one, ... | | 著者 | Cassetta, A, Lamba, D, Krastanova, I. | | 登録日 | 2012-06-11 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for inhibition of 17 beta-hydroxysteroid dehydrogenases by phytoestrogens: The case of fungal 17 beta-HSDcl.
J. Steroid Biochem. Mol. Biol., 171, 2017
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3CUV
 | | Tracking structure activity relationships of glycogen phosphorylase inhibitors: synthesis, kinetic and crystallographic evaluation of analogues of N-(-D-glucopyranosyl)-N'-oxamides | | 分子名称: | DIMETHYL SULFOXIDE, Glycogen phosphorylase, muscle form, ... | | 著者 | Kyritsi, C, Chrysina, E.D, Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | | 登録日 | 2008-04-17 | | 公開日 | 2009-04-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Tracking structure activity relationships of glycogen phosphorylase inhibitors: synthesis, kinetic and crystallographic evaluation of analogues of N-(-D-glucopyranosyl)-N'-oxamides
To be Published
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3CV6
 | | The crystal structure of mouse 17-alpha hydroxysteroid dehydrogenase GG225.226PP mutant in complex with inhibitor and cofactor NADP+. | | 分子名称: | 4-[(1R,2S)-1-ethyl-2-(4-hydroxyphenyl)butyl]phenol, Aldo-keto reductase family 1 member C21, BETA-MERCAPTOETHANOL, ... | | 著者 | Dhagat, U, El-Kabbani, O. | | 登録日 | 2008-04-17 | | 公開日 | 2009-03-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.
Acta Crystallogr.,Sect.D, 65, 2009
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4FFD
 | | Crystal structure of engineered protein. northeast structural genomics consortium target or48 | | 分子名称: | MAGNESIUM ION, PF00702 DOMAIN PROTEIN | | 著者 | Seetharaman, J, Lew, S, Nivon, L, Baker, D, Bjelic, S, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2012-05-31 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal structure of engineered protein. northeast structural genomics consortium target or48
To be Published
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4FJN
 | | RB69 DNA polymerase ternary complex with dTTP/dA | | 分子名称: | CALCIUM ION, DNA polymerase, DNA primer, ... | | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | | 登録日 | 2012-06-11 | | 公開日 | 2012-12-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase.
J.Am.Chem.Soc., 135, 2013
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4FK6
 | | JAK1 kinase (JH1 domain) in complex with compound 72 | | 分子名称: | N-({1-[(1R,2R,4S)-bicyclo[2.2.1]hept-2-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl}methyl)methanesulfonamide, Tyrosine-protein kinase JAK1 | | 著者 | Eigenbrot, C, Steffek, M. | | 登録日 | 2012-06-12 | | 公開日 | 2012-11-07 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2.
Bioorg.Med.Chem.Lett., 22, 2012
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4FGI
 | | Structure of the effector - immunity system Tse1 / Tsi1 from Pseudomonas aeruginosa | | 分子名称: | Tse1, Tsi1 | | 著者 | Benz, J, Sendlmeier, C, Barends, T.R.M, Meinhart, A. | | 登録日 | 2012-06-04 | | 公開日 | 2012-06-20 | | 最終更新日 | 2012-07-25 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Insights into the Effector - Immunity System Tse1/Tsi1 from Pseudomonas aeruginosa.
Plos One, 7, 2012
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4FHF
 | | Spore photoproduct lyase C140A mutant with dinucleoside spore photoproduct | | 分子名称: | 1-[(2R,4S,5R)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-5-[[(5R)-1-[(2R,4S,5R)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-5-methyl-2,4-bis(oxidanylidene)-1,3-diazinan-5-yl]methyl]pyrimidine-2,4-dione, IRON/SULFUR CLUSTER, PYROPHOSPHATE 2-, ... | | 著者 | Benjdia, A, Heil, K, Barends, T.R.M, Carell, T, Schlichting, I. | | 登録日 | 2012-06-06 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme.
Nucleic Acids Res., 40, 2012
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4FKJ
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4FHT
 | | Crystal Structure of the PcaV transcriptional regulator from Streptomyces coelicolor in complex with its natural ligand | | 分子名称: | 3,4-DIHYDROXYBENZOIC ACID, ACETATE ION, PcaV transcriptional regulator | | 著者 | Brown, B.L, Davis, J.R, Sello, J.K, Page, R. | | 登録日 | 2012-06-06 | | 公開日 | 2013-04-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Study of PcaV from Streptomyces coelicolor yields new insights into ligand-responsive MarR family transcription factors.
Nucleic Acids Res., 41, 2013
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3CW9
 | | 4-Chlorobenzoyl-CoA Ligase/Synthetase in the Thioester-forming Conformation, bound to 4-chlorophenacyl-CoA | | 分子名称: | 1,2-ETHANEDIOL, 4-Chlorophenacyl-coenzyme A, 4-chlorobenzoyl CoA ligase, ... | | 著者 | Reger, A.S, Cao, J, Wu, R, Dunaway-Mariano, D, Gulick, A.M. | | 登録日 | 2008-04-21 | | 公開日 | 2008-09-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural characterization of a 140 degrees domain movement in the two-step reaction catalyzed by 4-chlorobenzoate:CoA ligase.
Biochemistry, 47, 2008
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4FKW
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3CWX
 | | Crystal structure of cagd from helicobacter pylori pathogenicity island | | 分子名称: | protein CagD | | 著者 | Cendron, L, Zanotti, G, Angelini, A, Barison, N, Couturier, M, Stein, M. | | 登録日 | 2008-04-23 | | 公開日 | 2008-12-30 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Helicobacter pylori CagD (HP0545, Cag24) protein is essential for CagA translocation and maximal induction of interleukin-8 secretion.
J.Mol.Biol., 386, 2009
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3CX9
 | | Crystal Structure of Human serum albumin complexed with Myristic acid and lysophosphatidylethanolamine | | 分子名称: | (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, MYRISTIC ACID, Serum albumin | | 著者 | Guo, S, Yang, F, Chen, L, Bian, C, Huang, M. | | 登録日 | 2008-04-24 | | 公開日 | 2009-04-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis of transport of lysophospholipids by human serum albumin.
Biochem.J., 423, 2009
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4FIK
 | | Human carbonic anhydrase II H64A complexed with thioxolone hydrolysis products | | 分子名称: | 2,4-dihydroxybenzenesulfenic acid, 4,4'-disulfanediyldibenzene-1,3-diol, 4-MERCAPTOBENZENE-1,3-DIOL, ... | | 著者 | Sippel, K.H, Genis, C, Govindasamy, L, Agbandje-McKenna, M, Tripp, B.C, McKenna, R. | | 登録日 | 2012-06-08 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Synchrotron Radiation Provides a Plausible Explanation for the Generation of a Free Radical Adduct of Thioxolone in Mutant Carbonic Anhydrase II.
J Phys Chem Lett, 1, 2010
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4FLM
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3CXR
 | | Crystal structure of gluconate 5-dehydrogase from streptococcus suis type 2 | | 分子名称: | Dehydrogenase with different specificities | | 著者 | Peng, H, Gao, F, Zhang, Q, Liu, Y, Gao, G.F. | | 登録日 | 2008-04-25 | | 公開日 | 2009-03-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insight into the catalytic mechanism of gluconate 5-dehydrogenase from Streptococcus suis: Crystal structures of the substrate-free and quaternary complex enzymes.
Protein Sci., 18, 2009
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4FLZ
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4FMF
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3CXZ
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4FIX
 | | Crystal Structure of GlfT2 | | 分子名称: | BETA-MERCAPTOETHANOL, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Wheatley, R.W, Zheng, R.B, Lowary, T.L, Ng, K.K.S. | | 登録日 | 2012-06-11 | | 公開日 | 2012-06-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Tetrameric Structure of the GlfT2 Galactofuranosyltransferase Reveals a Scaffold for the Assembly of Mycobacterial Arabinogalactan.
J.Biol.Chem., 287, 2012
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