PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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7Q24	Crystal structure of Angiotensin-1 converting enzyme N-domain in complex with dual ACE/NEP inhibitor AD011 分子名称: (2~{S})-2-[[(2~{S})-1-[[(2~{S})-3-(1~{H}-indol-3-yl)-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-hexan-2-yl]amino]-4-phenyl-butanoic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2021-10-23 公開日 2022-02-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Probing the Requirements for Dual Angiotensin-Converting Enzyme C-Domain Selective/Neprilysin Inhibition. J.Med.Chem., 65, 2022
7Q25	Crystal structure of Angiotensin-1 converting enzyme N-domain in complex with dual ACE/NEP inhibitor AD012 分子名称: (2~{S})-2-[[(2~{S})-1-[[(2~{S})-3-(4-hydroxyphenyl)-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-hexan-2-yl]amino]-4-phenyl-butanoic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2021-10-23 公開日 2022-02-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Probing the Requirements for Dual Angiotensin-Converting Enzyme C-Domain Selective/Neprilysin Inhibition. J.Med.Chem., 65, 2022
7K4M	Crystal structure of MetAP2 Modified Hemoglobin S 分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... 著者 Musayev, F.N, Safo, M.K, Light, D.R. 登録日 2020-09-15 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 MetAP2 inhibition modifies hemoglobin S to delay polymerization and improves blood flow in sickle cell disease. Blood Adv, 5, 2021
7Q29	Crystal structure of Angiotensin-1 converting enzyme C-domain in complex with dual ACE/NEP inhibitor AD013 分子名称: (2~{S},5~{R})-5-(4-methylphenyl)-1-[2-[[(2~{S})-1-oxidanyl-1-oxidanylidene-4-phenyl-butan-2-yl]amino]ethanoyl]pyrrolidine-2-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2021-10-23 公開日 2022-02-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Probing the Requirements for Dual Angiotensin-Converting Enzyme C-Domain Selective/Neprilysin Inhibition. J.Med.Chem., 65, 2022
8QND	Crystal structure of the ribonucleoside hydrolase C from Lactobacillus reuteri 分子名称: CALCIUM ION, Inosine-uridine nucleoside N-ribohydrolase 著者 Matyuta, I.O, Minyaev, M.E, Shaposhnikov, L.A, Pometun, E.V, Tishkov, V.I, Popov, V.O, Boyko, K.M. 登録日 2023-09-26 公開日 2023-12-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-Functional Examination of Novel Ribonucleoside Hydrolase C (RihC) from Limosilactobacillus reuteri LR1. Int J Mol Sci, 25, 2023
6XRI	MSMEG_2027 domain-swapped dimer 分子名称: Uncharacterized protein 著者 Jackson, C.J, Antoney, J.P, Ahmed, F.H. 登録日 2020-07-13 公開日 2021-07-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structure of F420-H2 dependent oxidoreductase MSMEG_2027 in dimeric apo form. To Be Published
5TVW	Crystal structure of mitochondrial Hsp90 (TRAP1) with ATP in absence of Mg, hemi-hydrolyzed 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, COBALT (II) ION, ... 著者 Elnatan, D, Betegon, M, Agard, D.A, Northeast Structural Genomics Consortium (NESG) 登録日 2016-11-10 公開日 2018-03-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Symmetry broken and rebroken during the ATP hydrolysis cycle of the mitochondrial Hsp90 TRAP1. Elife, 6, 2017
5EWL	CRYSTAL STRUCTURE OF AMINO TERMINAL DOMAINS OF THE NMDA RECEPTOR SUBUNIT GLUN1 AND GLUN2B IN COMPLEX WITH MK-22 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 2B, ... 著者 Pandit, J. 登録日 2015-11-20 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective Antagonists. Mol.Pharmacol., 89, 2016
7Q4S	Structure of the Pseudomonas aeruginosa bacteriophage JG004 endolysin Pae87, apo form. 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Endolysin, TETRAETHYLENE GLYCOL 著者 Seoane-Blanco, M, van Raaij, M.J. 登録日 2021-11-02 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Monomodular Pseudomonas aeruginosa phage JG004 lysozyme (Pae87) contains a bacterial surface-active antimicrobial peptide-like region and a possible substrate-binding subdomain. Acta Crystallogr D Struct Biol, 78, 2022
7ZZK	Structure of the N-acetyl-D-glucosamine oxidase from Ralstonia Solanacearum 分子名称: ALANINE, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Boverio, A, Rozeboom, H.J, Fraaije, M.W. 登録日 2022-05-25 公開日 2022-08-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Elucidation and Engineering of a Bacterial Carbohydrate Oxidase. Biochemistry, 62, 2023
7K6Y	Structure of the PTP-like myo-inositol phosphatase from Desulfovibrio magneticus (high salt) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, GLYCEROL, ... 著者 Van Herk, P.H, Cleland, C.P, Mosimann, S.C. 登録日 2020-09-21 公開日 2021-11-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure of the PTP-like myo-inositol phosphatase from Desulfovibrio magneticus (high salt) To Be Published
8QB3	ADDobody zinc containing condition 分子名称: ADDobody, ZINC ION 著者 Buzas, D, Toelzer, C, Berger, I, Schaffitzel, C. 登録日 2023-08-24 公開日 2023-12-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders. Structure, 32, 2024
7Q4T	Structure of the Pseudomonas aeruginosa bacteriophage JG004 endolysin Pae87 bound to a peptidoglycan fragment. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, ALA-DGL, ... 著者 Seoane-Blanco, M, van Raaij, M.J. 登録日 2021-11-02 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Monomodular Pseudomonas aeruginosa phage JG004 lysozyme (Pae87) contains a bacterial surface-active antimicrobial peptide-like region and a possible substrate-binding subdomain. Acta Crystallogr D Struct Biol, 78, 2022
7ZGW	Serratia NucC apo form 分子名称: Serratia NucC 著者 Garcia-Doval, C, Mayo-Munoz, D, Smith, L.M, Fineran, P.C. 登録日 2022-04-04 公開日 2022-10-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Type III CRISPR-Cas provides resistance against nucleus-forming jumbo phages via abortive infection. Mol.Cell, 82, 2022
8QFQ	Ergothioneine dioxygenase, variant H147A, from Thermocatellispora tengchongensis in complex with manganese 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Cysteine dioxygenase, ... 著者 Vasseur, C.M, Seebeck, F.P. 登録日 2023-09-04 公開日 2023-12-27 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Enzyme-Catalyzed Oxidative Degradation of Ergothioneine. Angew.Chem.Int.Ed.Engl., 63, 2024
5TX5	Rip1 Kinase ( flag 1-294, C34A, C127A, C233A, C240A) with GSK772 分子名称: 3-benzyl-N-[(3S)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-5-carboxamide, Receptor-interacting serine/threonine-protein kinase 1 著者 Campobasso, N, Ward, P, Thrope, J. 登録日 2016-11-15 公開日 2017-07-05 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases. J. Med. Chem., 60, 2017
7K1R	X-ray Structure of an Enterobacter GH43 Beta-Xylosidase: EcXyl43 F507A mutant 分子名称: Beta xylosidase GH43, CALCIUM ION, GLYCEROL 著者 Briganti, L, Capetti, C.C.M, Polikarpov, I. 登録日 2020-09-08 公開日 2021-11-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 X-ray Structure of an Enterobacter GH43 Beta-Xylosidase: EcXyl43 F507A mutant To Be Published
6XOD	Crystal structure of the PEX4-PEX22 protein complex from Arabidopsis thaliana 分子名称: Peroxisome biogenesis protein 22, Protein PEROXIN-4 著者 Olmos Jr, J.L, Bradford, S.E, Miller, M.D, Xu, W, Wright, Z.J, Bartel, B, Phillips Jr, G.N. 登録日 2020-07-06 公開日 2021-07-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 The Structure of the Arabidopsis PEX4-PEX22 Peroxin Complex-Insights Into Ubiquitination at the Peroxisomal Membrane Front Cell Dev Biol, 10, 2022
8QC3	Crystal structure of oxidoreductive sulfoquinovosidase from Arthrobacter sp. U41 (ArSqgA)in complex with co-factor NAD+ 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Oxidoreductase 著者 Sharma, M, Davies, G.J. 登録日 2023-08-25 公開日 2023-12-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Widespread Family of NAD + -Dependent Sulfoquinovosidases at the Gateway to Sulfoquinovose Catabolism. J.Am.Chem.Soc., 145, 2023
8R8A	Structure of the N-terminal domain of CMA in complex with N-acetyllactosamine 分子名称: CADMIUM ION, Nigrin b-like, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose 著者 Lundstrom, J, Varrot, A. 登録日 2023-11-28 公開日 2023-12-27 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.317 Å) 主引用文献 Elucidating the glycan-binding specificity and structure of Cucumis melo agglutinin, a new R-type lectin. Beilstein J Org Chem, 20, 2024
7K67	Structure of the PTP-like myo-inositol phosphatase from Desulfovibrio magneticus 分子名称: D(-)-TARTARIC ACID, GLYCEROL, Myo-inositol phosphohydrolase, ... 著者 Cleland, C.P, Van Herk, P.H, Mosimann, S.C. 登録日 2020-09-18 公開日 2021-11-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of the PTP-like myo-inositol phosphatase from Desulfovibrio magneticus To Be Published
5TXI	Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftobiprole 分子名称: (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ... 著者 Alexander, J.A.N, Strynadka, N.C.J. 登録日 2016-11-16 公開日 2018-05-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 2018
7ZOT	crystal structure of PLAAT4 N-terminal domain 分子名称: DI(HYDROXYETHYL)ETHER, Phospholipase A and acyltransferase 4 著者 von Castelmur, E, Perrakis, A, Cornaciu, I. 登録日 2022-04-26 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.735 Å) 主引用文献 Crystal structure of the phospholipase A and acyltransferase 4 (PLAAT4) catalytic domain. J.Struct.Biol., 214, 2022
8QFM	Ergothioneine dioxygenase from Thermocatellispora tengchongensis in complex with manganese 分子名称: 1,2-ETHANEDIOL, Cysteine dioxygenase, DI(HYDROXYETHYL)ETHER, ... 著者 Vasseur, C.M, Seebeck, F.P. 登録日 2023-09-04 公開日 2023-12-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Enzyme-Catalyzed Oxidative Degradation of Ergothioneine. Angew.Chem.Int.Ed.Engl., 63, 2024
7K6W	Structure of the PTP-like myo-inositol phosphatase from Desulfovibrio magneticus in complex with myo-inositol hexakisphosphate 分子名称: ACETATE ION, INOSITOL HEXAKISPHOSPHATE, Myo-inositol phosphohydrolase, ... 著者 Cleland, C.P, Mosimann, S.C. 登録日 2020-09-21 公開日 2021-11-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the PTP-like myo-inositol phosphatase from Desulfovibrio magneticus in complex with myo-inositol hexakisphosphate To Be Published

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