7CPN
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![BU of 7cpn by Molmil](/molmil-images/mine/7cpn) | CRYSTAL STRUCTURE OF DODECAPRENYL DIPHOSPHATE SYNTHASE FROM THERMOBIFIDA FUSCA | 分子名称: | GLYCEROL, SULFATE ION, Trans,polycis-polyprenyl diphosphate synthase ((2Z,6E)-farnesyl diphosphate specific) | 著者 | Kurokawa, H, Ambo, T, Takahasi, S, Koyama, T. | 登録日 | 2020-08-07 | 公開日 | 2020-10-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Crystal structure of Thermobifida fusca cis-prenyltransferase reveals the dynamic nature of its RXG motif-mediated inter-subunit interactions critical for its catalytic activity. Biochem.Biophys.Res.Commun., 532, 2020
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7CI7
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![BU of 7ci7 by Molmil](/molmil-images/mine/7ci7) | Crystal structure of P.aeruginosa LpxC in complex with inhibitor | 分子名称: | (2R,3R)-2-azanyl-1-[4-[[4-[2-[4-(hydroxymethyl)phenyl]ethynyl]phenyl]methyl]piperidin-1-yl]-4-methylsulfonyl-3-oxidanyl-butan-1-one, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION | 著者 | Mima, M, Baker, L.M, Surgenor, A, Robertson, A. | 登録日 | 2020-07-07 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity. J.Med.Chem., 63, 2020
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7CR1
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![BU of 7cr1 by Molmil](/molmil-images/mine/7cr1) | human KCNQ2 in complex with ztz240 | 分子名称: | N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | 登録日 | 2020-08-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CX9
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![BU of 7cx9 by Molmil](/molmil-images/mine/7cx9) | Crystal structure of the SARS-CoV-2 main protease in complex with INZ-1 | 分子名称: | 3-iodanyl-1~{H}-indazole-7-carbaldehyde, 3C-like proteinase, CHLORIDE ION, ... | 著者 | Zeng, R, Liu, X.L, Qiao, J.X, Nan, J.S, Wang, Y.F, Li, Y.S, Yang, S.Y, Lei, J. | 登録日 | 2020-09-01 | 公開日 | 2020-09-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystal structure of the SARS-CoV-2 main protease in complex with INZ-1 To Be Published
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7C7S
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![BU of 7c7s by Molmil](/molmil-images/mine/7c7s) | Cryo-EM structure of the CGP54626-bound human GABA(B) receptor in inactive state. | 分子名称: | (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | 著者 | Mao, C, Shen, C, Li, C, Shen, D, Xu, C, Zhang, S, Zhou, R, Shen, Q, Chen, L, Jiang, Z, Liu, J, Zhang, Y. | 登録日 | 2020-05-26 | 公開日 | 2020-07-01 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of inactive and active GABABreceptor. Cell Res., 30, 2020
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7C8R
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![BU of 7c8r by Molmil](/molmil-images/mine/7c8r) | Complex Structure of SARS-CoV-2 3CL Protease with TG-0203770 | 分子名称: | 3C-like proteinase, ethyl (4R)-4-[[(2S)-4-methyl-2-[[(2S,3R)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)butanoyl]amino]pentanoyl]amino]-5-[(3S)-2-oxidanylidenepyrrolidin-3-yl]pentanoate | 著者 | Lee, C.C, Wang, A.H.J, Kuo, C.J, Liang, P.H. | 登録日 | 2020-06-03 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Complex Structures and Cellular Activities of the Potent SARS-CoV-2 3CLpro Inhibitors Guiding Drug Discovery Against COVID-19 To Be Published
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7CBD
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![BU of 7cbd by Molmil](/molmil-images/mine/7cbd) | Catalytic domain of Cellulomonas fimi Cel6B | 分子名称: | Exoglucanase A | 著者 | Nakamura, A, Ishiwata, D, Visootsat, A, Uchiyama, T, Mizutani, K, Kaneko, S, Murata, T, Igarashi, K, Iino, R. | 登録日 | 2020-06-12 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Domain architecture divergence leads to functional divergence in binding and catalytic domains of bacterial and fungal cellobiohydrolases. J.Biol.Chem., 295, 2020
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7CBS
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![BU of 7cbs by Molmil](/molmil-images/mine/7cbs) | Crystal structure of SpaB basal pilin from Lactobacillus rhamnosus GG | 分子名称: | CHLORIDE ION, LPXTG cell wall anchor domain-containing protein, MAGNESIUM ION | 著者 | Megta, A.K, Pratap, S, Kant, A, Krishnan, V. | 登録日 | 2020-06-13 | 公開日 | 2020-12-30 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Crystal structure of the atypically adhesive SpaB basal pilus subunit: Mechanistic insights about its incorporation in lactobacillar SpaCBA pili. Curr Res Struct Biol, 2, 2020
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5MO3
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7CEH
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![BU of 7ceh by Molmil](/molmil-images/mine/7ceh) | Crystal structure of PET-degrading cutinase Cut190 S176A/S226P/R228S/ mutant with the C-terminal three residues deletion in ligand ejecting form | 分子名称: | Alpha/beta hydrolase family protein, CALCIUM ION | 著者 | Senga, A, Numoto, N, Ito, N, Kawai, F, Oda, M. | 登録日 | 2020-06-23 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Multiple structural states of Ca2+-regulated PET hydrolase, Cut190, and its correlation with activity and stability. J.Biochem., 169, 2021
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7C2O
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![BU of 7c2o by Molmil](/molmil-images/mine/7c2o) | Crystal structure of the R-specific Carbonyl Reductase from Candida parapsilosis ATCC 7330 without DTT | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, R-specific carbonyl reductase, ... | 著者 | Vinaykumar, K, KanalElamparithi, B, Chaudhury, D, Gunasekaran, K, Chadha, A. | 登録日 | 2020-05-08 | 公開日 | 2020-05-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of the R-specific Carbonyl Reductase from Candida parapsilosis ATCC 7330 without DTT To Be Published
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8TGO
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![BU of 8tgo by Molmil](/molmil-images/mine/8tgo) | Crystal structure of the BG505 triple tandem trimer gp140 HIV-1 Env in complex with PGT124 and 35O22 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv, ... | 著者 | Xian, Y, Yuan, M, Wilson, I.A. | 登録日 | 2023-07-12 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (5.75 Å) | 主引用文献 | Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines. Npj Vaccines, 9, 2024
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7CI8
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![BU of 7ci8 by Molmil](/molmil-images/mine/7ci8) | Crystal structure of P.aeruginosa LpxC in complex with inhibitor | 分子名称: | (1S)-1-[1-[(5-phenyl-1,2-oxazol-3-yl)methyl]imidazol-2-yl]ethanol, MAGNESIUM ION, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... | 著者 | Mima, M, Baker, L.M, Surgenor, A, Robertson, A. | 登録日 | 2020-07-07 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity. J.Med.Chem., 63, 2020
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3NKM
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![BU of 3nkm by Molmil](/molmil-images/mine/3nkm) | Crystal structure of mouse autotaxin | 分子名称: | (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O. | 登録日 | 2010-06-20 | 公開日 | 2011-01-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | Crystal structure of autotaxin and insight into GPCR activation by lipid mediators Nat.Struct.Mol.Biol., 18, 2011
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7CIE
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![BU of 7cie by Molmil](/molmil-images/mine/7cie) | Crystal structure of P.aeruginosa LpxC in complex with inhibitor | 分子名称: | (2R)-2-azanyl-3-oxidanyl-N-[3-(trifluoromethyloxy)phenyl]propanamide, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION | 著者 | Baker, L.M, Mima, M, Surgenor, A, Robertson, A. | 登録日 | 2020-07-07 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity. J.Med.Chem., 63, 2020
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7AAR
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![BU of 7aar by Molmil](/molmil-images/mine/7aar) | sugar/H+ symporter STP10 in inward open conformation | 分子名称: | CHLORIDE ION, Octyl Glucose Neopentyl Glycol, Sugar transport protein 10, ... | 著者 | Bavnhoej, L, Paulsen, P.A, Pedersen, B.P. | 登録日 | 2020-09-04 | 公開日 | 2021-08-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Molecular mechanism of sugar transport in plants unveiled by structures of glucose/H + symporter STP10. Nat.Plants, 7, 2021
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7CI6
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![BU of 7ci6 by Molmil](/molmil-images/mine/7ci6) | Crystal structure of P.aeruginosa LpxC in complex with inhibitor | 分子名称: | (1S)-1-[1-[3-(4-chlorophenyl)propyl]imidazol-2-yl]ethanol, CHLORIDE ION, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... | 著者 | Mima, M, Baker, L.M, Surgenor, A, Robertson, A. | 登録日 | 2020-07-07 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity. J.Med.Chem., 63, 2020
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7CMG
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![BU of 7cmg by Molmil](/molmil-images/mine/7cmg) | The Structure of the periplasmic domain of PorM | 分子名称: | Por secretion system protein porM/gldM | 著者 | Sato, K, Okada, K, Nakayam, K, Imada, K. | 登録日 | 2020-07-27 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | PorM, a core component of bacterial type IX secretion system, forms a dimer with a unique kinked-rod shape. Biochem.Biophys.Res.Commun., 532, 2020
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7CQJ
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8TFL
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![BU of 8tfl by Molmil](/molmil-images/mine/8tfl) | Ricin in complex with Fab SylH3 | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, NONAETHYLENE GLYCOL, ... | 著者 | Rudolph, M.J, Mantis, N. | 登録日 | 2023-07-11 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Structural Basis of Antibody-Mediated Inhibition of Ricin Toxin Attachment to Host Cells. Biochemistry, 62, 2023
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7CUC
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7CTS
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![BU of 7cts by Molmil](/molmil-images/mine/7cts) | Open form of PET-degrading cutinase Cut190 with thermostability-improving mutations of S226P/R228S/Q138A/D250C-E296C/Q123H/N202H and S176A inactivation | 分子名称: | 1,4-DIETHYLENE DIOXIDE, Alpha/beta hydrolase family protein, BICINE, ... | 著者 | Emori, M, Numoto, N, Senga, A, Bekker, G.J, Kamiya, N, Ito, N, Kawai, F, Oda, M. | 登録日 | 2020-08-20 | 公開日 | 2021-02-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Structural basis of mutants of PET-degrading enzyme from Saccharomonospora viridis AHK190 with high activity and thermal stability. Proteins, 89, 2021
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7AAQ
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![BU of 7aaq by Molmil](/molmil-images/mine/7aaq) | sugar/H+ symporter STP10 in outward occluded conformation | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, ACETATE ION, ... | 著者 | Bavnhoej, L, Paulsen, P.A, Pedersen, B.P. | 登録日 | 2020-09-04 | 公開日 | 2021-08-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Molecular mechanism of sugar transport in plants unveiled by structures of glucose/H + symporter STP10. Nat.Plants, 7, 2021
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7CV0
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![BU of 7cv0 by Molmil](/molmil-images/mine/7cv0) | Crystal structure of B. halodurans NiaR in apo form | 分子名称: | Transcriptional regulator NiaR, ZINC ION | 著者 | Lee, J.Y, Lee, D.W, Park, Y.W, Lee, M.Y, Jeong, K.H. | 登録日 | 2020-08-25 | 公開日 | 2020-12-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Structural analysis and insight into effector binding of the niacin-responsive repressor NiaR from Bacillus halodurans. Sci Rep, 10, 2020
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7C7H
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