PDB: 41522 件ウェブページステータス検索Chemie searchBIRD

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8UKQ	RNA polymerase II elongation complex with Fapy-dG lesion in apo state 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Hou, P, Oh, J, Wang, D. 登録日 2023-10-15 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
8VE2	Unliganded human transthyretin in the canonical conformation 分子名称: Transthyretin 著者 Basanta, B, Nugroho, K, Yan, N, Kline, G.M, Tsai, F.J, Wu, M, Kelly, J.W, Lander, G.C. 登録日 2023-12-18 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The conformational landscape of human transthyretin revealed by cryo-EM To Be Published
8TN6	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - holo rucaparib 分子名称: De novo designed protein, Rucaparib 著者 Lu, L, DeGrado, W.F. 登録日 2023-08-01 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
8WUC	Cryo-EM structure of H. thermoluteolus GroEL-GroES2 football complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... 著者 Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. 登録日 2023-10-20 公開日 2024-03-27 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structural insights into thermophilic chaperonin complexes. Structure, 32, 2024
8WVB	Crystal structure of Lsd18 mutant S195M 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Putative epoxidase LasC 著者 Liu, N, Xiao, H.L, Chen, X. 登録日 2023-10-23 公開日 2023-12-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Simultaneous Improvement in the Thermostability and Catalytic Activity of Epoxidase Lsd18 for the Synthesis of Lasalocid A. Int J Mol Sci, 24, 2023
8WVF	Crystal structure of Lsd18 mutant T189M and S195M 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Putative epoxidase LasC 著者 Liu, N, Xiao, H.L, Chen, X. 登録日 2023-10-23 公開日 2023-12-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.757 Å) 主引用文献 Simultaneous Improvement in the Thermostability and Catalytic Activity of Epoxidase Lsd18 for the Synthesis of Lasalocid A. Int J Mol Sci, 24, 2023
8VE1	Human transthyretin covalently modified with A2-derived stilbene in the canonical conformation 分子名称: 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoic acid, Transthyretin 著者 Basanta, B, Nugroho, K, Yan, N, Kline, G.M, Tsai, F.J, Wu, M, Kelly, J.W, Lander, G.C. 登録日 2023-12-18 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 The conformational landscape of human transthyretin revealed by cryo-EM To Be Published
8VQL	Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule 6S prime 分子名称: (S~1~S,3S)-N-{3,5-dichloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-3-(dimethylamino)pyrrolidine-1-sulfonimidoyl fluoride, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Lin, T.H, Zhu, Y, Wilson, I.A. 登録日 2024-01-18 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
8VQQ	Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule 6S 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... 著者 Lin, T.H, Zhu, Y, Wilson, I.A. 登録日 2024-01-19 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
8V1H	Crystal structure of human pre-mascRNA 分子名称: SODIUM ION, pre-mascRNA 著者 Skeparnias, I, Zhang, J. 登録日 2023-11-20 公開日 2024-07-10 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Structural basis of MALAT1 RNA maturation and mascRNA biogenesis. Nat.Struct.Mol.Biol., 2024
9F3X	CutC choline lyase in complex with cyclopropylcholine 分子名称: Choline trimethylamine-lyase, cyclopropylcholine 著者 Kalnins, G. 登録日 2024-04-26 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 CutC choline lyase in complex with fluoromethylcholine To Be Published
8VE5	(Biarylamine-FT2-WT)1(C10A)3-human transthyretin in the compressed conformation 分子名称: 2-[(3,5-DICHLORO-4-TRIOXIDANYLPHENYL)AMINO]BENZOIC ACID, Transthyretin 著者 Basanta, B, Nugroho, K, Yan, N, Kline, G.M, Tsai, F.J, Wu, M, Kelly, J.W, Lander, G.C. 登録日 2023-12-18 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 The conformational landscape of human transthyretin revealed by cryo-EM To Be Published
9FCH	P116 dimer in the full state (PDB structure of the full-length ectodomain truncated to amino acids 246-818) 分子名称: Uncharacterized protein MG075 homolog 著者 Mager, S. 登録日 2024-05-15 公開日 2024-05-29 実験手法 ELECTRON MICROSCOPY (6.52 Å) 主引用文献 P116 from Mycoplasma is a self-sufficient lipid uptake and delivery machinery To Be Published
9ICH	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DGTP (1 MILLIMOLAR) AND ZNCL2 (1 MILLIMOLAR) 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-15 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
2J5S	Structural of ABDH, a beta-diketone hydrolase from the Cyanobacterium Anabaena sp. PCC 7120 bound to (S)-3-oxocyclohexyl acetic acid 分子名称: (S)-CYCLOHEXANONE-2-ACETATE, BETA-DIKETONE HYDROLASE, NICKEL (II) ION 著者 Bennett, J.P, Whittingham, J.L, Brzozowski, A.M, Leonard, P.M, Grogan, G. 登録日 2006-09-19 公開日 2007-01-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Structural Characterisation of a Beta Diketone Hydrolase from the Cyanobacterium Anabaena Sp. Pcc 7120 in Native and Product Bound Forms, a Coenzyme A-Independent Member of the Crotonase Suprafamily Biochemistry, 46, 2007
2J5I	Crystal Structure of Hydroxycinnamoyl-CoA Hydratase-Lyase 分子名称: P-HYDROXYCINNAMOYL COA HYDRATASE/LYASE 著者 Leonard, P.M, Brzozowski, A.M, Lebedev, A, Marshall, C.M, Smith, D.J, Verma, C.S, Walton, N.J, Grogan, G. 登録日 2006-09-18 公開日 2006-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The 1.8 A Resolution Structure of Hydroxycinnamoyl- Coenzyme a Hydratase-Lyase (Hchl) from Pseudomonas Fluorescens, an Enzyme that Catalyses the Transformation of Feruloyl-Coenzyme a to Vanillin. Acta Crystallogr.,Sect.D, 62, 2006
1UAN	Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8 分子名称: hypothetical protein TT1542 著者 Handa, N, Terada, T, Tame, J.R.H, Park, S.-Y, Kinoshita, K, Ota, M, Nakamura, H, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-03-12 公開日 2003-08-05 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8 PROTEIN SCI., 12, 2003
2J8U	Large CDR3a loop alteration as a function of MHC mutation. 分子名称: AHIII TCR ALPHA CHAIN, AHIII TCR BETA CHAIN, Beta-2-microglobulin, ... 著者 Miller, P.J, Benhar, Y.P, Biddison, W, Collins, E.J. 登録日 2006-10-27 公開日 2007-10-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Single MHC mutation eliminates enthalpy associated with T cell receptor binding. J. Mol. Biol., 373, 2007
2IUC	Structure of alkaline phosphatase from the Antarctic bacterium TAB5 分子名称: ALKALINE PHOSPHATASE, CACODYLATE ION, MAGNESIUM ION, ... 著者 Wang, E, Koutsioulis, D, Leiros, H.K.S, Andersen, O.A, Bouriotis, V, Hough, E, Heikinheimo, P. 登録日 2006-06-01 公開日 2006-11-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of Alkaline Phosphatase from the Antarctic Bacterium Tab5. J.Mol.Biol., 366, 2007
2IFF	STRUCTURE OF AN ANTIBODY-LYSOZYME COMPLEX: EFFECT OF A CONSERVATIVE MUTATION 分子名称: HEN EGG WHITE LYSOZYME, IGG1 HYHEL-5 FAB (HEAVY CHAIN), IGG1 HYHEL-5 FAB (LIGHT CHAIN) 著者 Chacko, S, Davies, D.R. 登録日 1994-02-03 公開日 1994-05-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure of an antibody-lysozyme complex unexpected effect of conservative mutation. J.Mol.Biol., 245, 1995
2JCC	AH3 recognition of mutant HLA-A2 W167A 分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, ... 著者 Miller, P, Benhar, Y.P, Biddison, W, Collins, E.J. 登録日 2006-12-21 公開日 2007-10-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Single Mhc Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding. J.Mol.Biol., 373, 2007
3NXS	Crystal structure of LAO/AO transport system from Mycobacterium smegmatis bound to GDP 分子名称: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, LAO/AO transport system ATPase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-07-14 公開日 2010-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of Mycobacterial MeaB and MMAA-like GTPases J.Struct.Funct.Genom., 16, 2015
3NYB	Structure and function of the polymerase core of TRAMP, a RNA surveillance complex 分子名称: Poly(A) RNA polymerase protein 2, Protein AIR2, ZINC ION 著者 Reinisch, K.M, Hamill, S. 登録日 2010-07-14 公開日 2010-08-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7007 Å) 主引用文献 Structure and function of the polymerase core of TRAMP, a RNA surveillance complex. Proc.Natl.Acad.Sci.USA, 107, 2010
2J5G	The Native structure of a beta-Diketone Hydrolase from the Cyanobacterium Anabaena sp. PCC 7120 分子名称: ALR4455 PROTEIN, SULFATE ION 著者 Bennett, J.P, Whittingham, J.L, Brzozowski, A.M, Leonard, P.M, Grogan, G. 登録日 2006-09-18 公開日 2007-01-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Structural Characterisation of a Beta Diketone Hydrolase from the Cyanobacterium Anabaena Sp. Pcc 7120 in Native and Product Bound Forms, a Coenzyme A-Independent Member of the Crotonase Suprafamily Biochemistry, 46, 2007
3FCE	Crystal Structure of Bacillus cereus D-alanyl Carrier Protein Ligase DltA in Complex with ATP: Implications for Adenylation Mechanism 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, D-alanine--poly(phosphoribitol) ligase subunit 1 著者 Osman, K.T, Du, L, He, Y, Luo, Y. 登録日 2008-11-21 公開日 2009-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Bacillus cereus D-alanyl carrier protein ligase (DltA) in complex with ATP. J.Mol.Biol., 388, 2009

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