PDB: 41522 件ウェブページステータス検索Chemie searchBIRD

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8U8K	Co-crystal structure of phosphorylated ERK2 in complex with ERK1/2 inhibitor #8 分子名称: (4M)-4-{(4S)-3-[(2-chloropyridin-3-yl)methyl][1,2,4]triazolo[4,3-a]pyridin-7-yl}-N-(oxan-4-yl)pyrimidin-2-amine, Mitogen-activated protein kinase 1 著者 Anderson, J.W, Vigers, G.P. 登録日 2023-09-18 公開日 2024-03-27 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Conformation selection by ATP-competitive inhibitors and allosteric communication in ERK2. Elife, 12, 2024
8Y0W	dormant ribosome with eIF5A, eEF2 and SERBP1 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Du, M, Zeng, F. 登録日 2024-01-23 公開日 2024-02-07 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 dormant ribosome with eIF5A, eEF2 and SERBP1 To Be Published
8TL0	Structure of activated SAVED-CHAT filament 分子名称: CHAT domain-containing protein, RNA (5'-R(*AP*AP*A)-3') 著者 Bravo, J.P.K, Taylor, D.W. 登録日 2023-07-26 公開日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Type III-B CRISPR-Cas cascade of proteolytic cleavages. Science, 383, 2024
8WDX	Crystal structure of human FABP4 complexed with C3 分子名称: 1,2-ETHANEDIOL, 2-[(3-chloranyl-2-phenyl-phenyl)amino]-6-methyl-benzoic acid, Fatty acid-binding protein, ... 著者 Xie, H, Chen, G.F, Xu, Y.C. 登録日 2023-09-16 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3. Eur.J.Med.Chem., 264, 2023
9ICE	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND CUCL2 (0.1 MILLIMOLAR) 分子名称: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-15 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
8XLN	Structure of the SARS-CoV-2 EG.5.1 spike RBD in complex with ACE2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... 著者 Nomai, T, Anraku, Y, Kita, S, Hashiguchi, T, Maenaka, K. 登録日 2023-12-26 公開日 2024-05-01 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant. Microbiol Immunol, 2024
8VQY	Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus methaqualone 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one, GAMMA-AMINO-BUTANOIC ACID, ... 著者 Chojnacka, W, Teng, J, Kim, J.J, Jensen, A.A, Hibbs, R.E. 登録日 2024-01-19 公開日 2024-06-26 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.82 Å) 主引用文献 Structural insights into GABA A receptor potentiation by Quaalude. Nat Commun, 15, 2024
8VE0	Human transthyretin covalently modified with A2-derived stilbene in the compressed conformation 分子名称: 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoic acid, Transthyretin 著者 Basanta, B, Nugroho, K, Yan, N, Kline, G.M, Tsai, F.J, Wu, M, Kelly, J.W, Lander, G.C. 登録日 2023-12-18 公開日 2024-01-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The conformational landscape of human transthyretin revealed by cryo-EM To Be Published
8VZO	Cryo-EM structure of FLVCR2 in the outward-facing state with choline bound 分子名称: CHOLINE ION, Fab FLV23 heavy chain, Fab FLV23 light chain, ... 著者 Cater, R.J, Mancia, F. 登録日 2024-02-12 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.49 Å) 主引用文献 Structural and molecular basis of choline uptake into the brain by FLVCR2. Nature, 629, 2024
8TRN	Actin 1 from T. gondii in filaments bound to MgADP and jasplakinolide 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, Jasplakinolide, ... 著者 Hvorecny, K.L, Sladewski, T.E, Heaslip, A.T, Kollman, J.M. 登録日 2023-08-09 公開日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Toxoplasma gondii actin filaments are tuned for rapid disassembly and turnover. Nat Commun, 15, 2024
9ICA	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-O-(1-THIOTRIPHOSPHATE), SOAKED IN THE PRESENCE OF DATP(ALPHA)S AND MNCL2 分子名称: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-15 公開日 1995-12-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9ICL	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF PYROPHOSPHATE AND MNCL2 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), MANGANESE (II) ION, ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-01-04 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis Biochemistry, 35, 1996
9ICC	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND CRCL3 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CHROMIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-15 公開日 1995-12-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
8UWU	EmrE structure in the proton-bound state (WT/L51I heterodimer) 分子名称: SMR family multidrug efflux protein EmrE 著者 Li, J, Sae Her, A, Besch, A, Ramirez, B, Crames, M, Banigan, J.R, Mueller, C, Marsiglia, W.M, Zhang, Y, Traaseth, N.J. 登録日 2023-11-08 公開日 2024-05-29 最終更新日 2024-07-03 実験手法 SOLID-STATE NMR, SOLUTION NMR 主引用文献 Dynamics underlie the drug recognition mechanism by the efflux transporter EmrE. Nat Commun, 15, 2024
9C0O	Crystal structure of DmCfp1 PHD finger bound to H3K4me3 分子名称: CXXC-type zinc finger protein 1, DIMETHYL SULFOXIDE, Histone H3.3C, ... 著者 Gregoire, S, Couture, J.F. 登録日 2024-05-27 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Structural insights into an atypical histone binding mechanism by a PHD finger. to be published
8XGC	Structure of yeast replisome associated with FACT and histone hexamer, Composite map 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... 著者 Li, N, Gao, Y, Yu, D, Gao, N, Zhai, Y. 登録日 2023-12-15 公開日 2024-02-14 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Parental histone transfer caught at the replication fork. Nature, 627, 2024
8WOM	Structure of the wild-type Arabidopsis ABCB19 in the brassinolide-bound state 分子名称: ABC transporter B family member 19, Brassinolide 著者 Ying, W, Wei, H, Liu, X, Sun, L. 登録日 2023-10-07 公開日 2024-03-13 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export. Science, 383, 2024
8WZK	Human erythrocyte catalase 分子名称: Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE 著者 Yadav, S, Vinothkumar, K.R. 登録日 2023-11-01 公開日 2024-07-10 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Factors affecting macromolecule orientations in thin films formed in cryo-EM. Acta Crystallogr D Struct Biol, 80, 2024
8VBT	Structure of the monofunctional Staphylococcus aureus PBP1 in its apo form 分子名称: Penicillin-binding protein 1 著者 Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J. 登録日 2023-12-12 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1. J.Struct.Biol., 216, 2024
8V1L	Crystal structure of the NTF2L domain of human G3BP1 in complex with small molecule 分子名称: N-[(2S)-2-fluoro-4,4-dimethylpentanoyl]-3-hydroxy-L-valyl-(betaS)-beta-methyl-L-phenylalanyl-D-alanyl-N-benzyl-N,O-dimethyl-L-homoserinamide, Ras GTPase-activating protein-binding protein 1 著者 Hughes, M.P, Taylor, J.P. 登録日 2023-11-20 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Identification of small molecule inhibitors of G3BP-driven stress granule formation. J.Cell Biol., 223, 2024
8WOI	Structure of the wild-type Arabidopsis ABCB19 in the apo state 分子名称: ABC transporter B family member 19 著者 Ying, W, Wei, H, Liu, X, Sun, L. 登録日 2023-10-07 公開日 2024-03-13 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export. Science, 383, 2024
8TLC	Human mitochondrial serine hydroxymethyltransferase (SHMT2) in complex with PLP, glycine and tri-glutamate AGF347 inhibitor 分子名称: N-{4-[4-(2-amino-4-oxo-1,4-dihydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)butyl]-2-fluorobenzoyl}-D-gamma-glutamyl-L-gamma-glutamyl-D-glutamic acid, Serine hydroxymethyltransferase, mitochondrial 著者 Katinas, J.M, Dann III, C.E. 登録日 2023-07-26 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2. Biochemistry, 2024
8V56	UIC-1 mutant - UIC-1-B5W 分子名称: UIC-1-B5W 著者 Heinz-Kunert, S.L. 登録日 2023-11-30 公開日 2024-03-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Pore Restructuring of Peptide Frameworks by Mutations at Distal Packing Residues. Biomacromolecules, 25, 2024
8VE9	IsPETase - ACCCETN mutant - CombiPETase 分子名称: CHLORIDE ION, GLYCEROL, Poly(ethylene terephthalate) hydrolase 著者 Joho, Y, Royan, S, Newton, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. 登録日 2023-12-18 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Enhancing PET Degrading Enzymes: A Combinatory Approach. Chembiochem, 25, 2024
9ICJ	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA 分子名称: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-15 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis Biochemistry, 35, 1996

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