7JYN
| Solution NMR structure of human Brd3 ET complexed with NSD3(148-184) peptide | 分子名称: | Bromodomain-containing protein 3, Histone-lysine N-methyltransferase NSD3 | 著者 | Aiyer, S, Swapna, G.V.T, Roth, M.J, Montelione, G.T. | 登録日 | 2020-08-31 | 公開日 | 2021-06-23 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins. Structure, 29, 2021
|
|
1FQV
| Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex | 分子名称: | SKP1, SKP2 | 著者 | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | 登録日 | 2000-09-06 | 公開日 | 2000-11-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408, 2000
|
|
5XMW
| Selenomethionine-derivated ZHD | 分子名称: | Zearalenone lactonase | 著者 | Hu, X.J. | 登録日 | 2017-05-16 | 公開日 | 2018-04-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structure of a complex of the lactonohydrolase zearalenone hydrolase with the hydrolysis product of zearalenone at 1.60 angstrom resolution Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
1FFJ
| NMR STRUCTURE OF CARDIOTOXIN IN DPC-MICELLE | 分子名称: | CYTOTOXIN 2 | 著者 | Dubovskii, P.V, Dementieva, D.V, Bocharov, E.V, Utkin, Y.N, Arseniev, A.S. | 登録日 | 2000-07-25 | 公開日 | 2001-01-17 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Membrane binding motif of the P-type cardiotoxin. J.Mol.Biol., 305, 2001
|
|
6Y0H
| High resolution structure of GH11 xylanase from Nectria haematococca | 分子名称: | Endo-1,4-beta-xylanase | 著者 | Andaleeb, H, Betzel, C, Perbandt, M, Brognaro, H. | 登録日 | 2020-02-07 | 公開日 | 2020-10-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | High-resolution crystal structure and biochemical characterization of a GH11 endoxylanase from Nectria haematococca. Sci Rep, 10, 2020
|
|
5CB3
| Structural Insights into the Mechanism of Escherichia coli Ymdb | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, O-acetyl-ADP-ribose deacetylase | 著者 | Zhang, W, Wang, C, Song, Y, Shao, C, Zhang, X, Zang, J. | 登録日 | 2015-06-30 | 公開日 | 2015-11-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the mechanism of Escherichia coli YmdB: A 2'-O-acetyl-ADP-ribose deacetylase J.Struct.Biol., 192, 2015
|
|
6Y15
| X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant T102E_Q126K | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, R-specific alcohol dehydrogenase | 著者 | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-02-11 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Contact Engineering Enables Efficient Capture and Purification of an Oxidoreductase by Technical Crystallization. Biotechnol J, 15, 2020
|
|
6Y1B
| X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant K32A_Q126K | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | 著者 | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-02-11 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal Contact Engineering Enables Efficient Capture and Purification of an Oxidoreductase by Technical Crystallization. Biotechnol J, 15, 2020
|
|
1FB5
| LOW RESOLUTION STRUCTURE OF OVINE ORNITHINE TRANSCARBMOYLASE IN THE UNLIGANDED STATE | 分子名称: | NORVALINE, ORNITHINE TRANSCARBAMOYLASE | 著者 | Zanotti, G, Battistutta, R, Panzalorto, M, Francescato, P, Bruno, G, De Gregorio, A. | 登録日 | 2000-07-14 | 公開日 | 2003-08-26 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Functional and structural characterization of ovine ornithine transcarbamoylase. Org.Biomol.Chem., 1, 2003
|
|
6Y8J
| Crystal structure of the apo form of a quaternary ammonium Rieske monooxygenase CntA | 分子名称: | Carnitine monooxygenase oxygenase subunit, FE2/S2 (INORGANIC) CLUSTER | 著者 | Quareshy, M, Shanmugam, M, Bugg, T.D, Cameron, A, Chen, Y. | 登録日 | 2020-03-05 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural basis of carnitine monooxygenase CntA substrate specificity, inhibition, and intersubunit electron transfer. J.Biol.Chem., 296, 2020
|
|
6Y5M
| Crystal structure of mouse Autotaxin in complex with compound 1a | 分子名称: | (~{E})-3-[4-chloranyl-2-[(5-methyl-1,2,3,4-tetrazol-2-yl)methyl]phenyl]-1-[(2~{R})-4-[(4-fluorophenyl)methyl]-2-methyl-piperazin-1-yl]prop-2-en-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Faller, M, Zink, F. | 登録日 | 2020-02-25 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.011 Å) | 主引用文献 | Development of autotaxin inhibitors: A series of tetrazole cinnamides. Bioorg.Med.Chem.Lett., 31, 2021
|
|
8QC4
| M. tuberculosis salicylate synthase MbtI in complex with 5-(3-carboxyphenyl)furan-2-carboxylic acid | 分子名称: | 5-(3-carboxyphenyl)furan-2-carboxylic acid, GLYCEROL, SULFATE ION, ... | 著者 | Mori, M, Villa, S, Meneghetti, F, Bellinzoni, M. | 登録日 | 2023-08-25 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.578 Å) | 主引用文献 | Structural Study of a New MbtI-Inhibitor Complex: Towards an Optimized Model for Structure-Based Drug Discovery. Pharmaceuticals, 16, 2023
|
|
5CLB
| |
5MI6
| BtGH84 mutant with covalent modification by MA3 in complex with Thiamet G | 分子名称: | (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL, 1,2-ETHANEDIOL, CALCIUM ION, ... | 著者 | Darby, J.F, Davies, G.J, Hubbard, R.E. | 登録日 | 2016-11-27 | 公開日 | 2017-11-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Increase of enzyme activity through specific covalent modification with fragments. Chem Sci, 8, 2017
|
|
8EY1
| |
6UO1
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA (containing pseudouridine at the first position of the codon) and deacylated A-, P-, and E-site tRNAs at 2.95A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Batool, Z, Dobosz-Bartoszek, M, Polikanov, Y.S. | 登録日 | 2019-10-14 | 公開日 | 2019-11-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Pseudouridinylation of mRNA coding sequences alters translation. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
8IGF
| Crystal Structure of Human Carbonic Anhydrase II In-complex with 4-Acetylphenylboronic acid at 2.6 A Resolution | 分子名称: | (4-ethanoylphenyl)boronic acid, Carbonic anhydrase 2, GLYCEROL, ... | 著者 | Rasheed, S, Huda, N, Fisher, S.Z, Falke, S, Gul, S, Ahmad, M.S, Choudhary, M.I. | 登録日 | 2023-02-20 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Identification, crystallization, and first X-ray structure analyses of phenyl boronic acid-based inhibitors of human carbonic anhydrase-II. Int.J.Biol.Macromol., 267, 2024
|
|
8EQV
| Cryo-EM structure of PRC2 in complex with the long isoform of AEBP2 | 分子名称: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, ... | 著者 | Boudes, M, Zhang, Q, Flanigan, S.F, Davidovich, C. | 登録日 | 2022-10-09 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | To be updated To Be Published
|
|
5MKM
| |
6Y79
| Cryo-EM structure of a respiratory complex I F89A mutant | 分子名称: | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | 著者 | Parey, K. | 登録日 | 2020-02-28 | 公開日 | 2020-10-28 | 最終更新日 | 2021-02-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Essential role of accessory subunit LYRM6 in the mechanism of mitochondrial complex I. Nat Commun, 11, 2020
|
|
5MSU
| |
5C0O
| m1A58 tRNA methyltransferase mutant - Y78A | 分子名称: | S-ADENOSYLMETHIONINE, SULFATE ION, tRNA (adenine(58)-N(1))-methyltransferase TrmI | 著者 | Degut, C, Ponchon, L, Folly-Klan, M, Barraud, P, Tisne, C. | 登録日 | 2015-06-12 | 公開日 | 2015-07-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | The m1A58 modification in eubacterial tRNA: An overview of tRNA recognition and mechanism of catalysis by TrmI. Biophys.Chem., 210, 2016
|
|
4XT1
| Structure of a nanobody-bound viral GPCR bound to human chemokine CX3CL1 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Fractalkine, ... | 著者 | Burg, J.S, Jude, K.M, Waghray, D, Garcia, K.C. | 登録日 | 2015-01-22 | 公開日 | 2015-03-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.886 Å) | 主引用文献 | Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor. Science, 347, 2015
|
|
6YND
| GAPDH purified from the supernatant of HEK293F cells: crystal form 1 of 4. | 分子名称: | 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Glyceraldehyde-3-phosphate dehydrogenase | 著者 | Roversi, P, Lia, A. | 登録日 | 2020-04-13 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.525 Å) | 主引用文献 | Partial catalytic Cys oxidation of human GAPDH to Cys-sulfonic acid. Wellcome Open Res, 5, 2020
|
|
5MJJ
| |