1YDN
| Crystal Structure of the HMG-CoA Lyase from Brucella melitensis, Northeast Structural Genomics Target LR35. | 分子名称: | CALCIUM ION, HYDROXYMETHYLGLUTARYL-COA LYASE | 著者 | Forouhar, F, Abashidze, M, Hussain, M, Vorobiev, S.M, Xiao, R, Ciano, M, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-12-24 | 公開日 | 2005-07-05 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds. J.Biol.Chem., 281, 2006
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3PIQ
| Crystal structure of human 2909 Fab, a quaternary structure-specific antibody against HIV-1 | 分子名称: | Human monoclonal antibody 2909 Fab heavy chain, Human monoclonal antibody 2909 Fab light chain | 著者 | Changela, A, Gorny, M.K, Zolla-Pazner, S, Kwong, P.D. | 登録日 | 2010-11-07 | 公開日 | 2011-01-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.325 Å) | 主引用文献 | Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1. J.Virol., 85, 2011
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1JLQ
| CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH 739W94 | 分子名称: | 2-AMINO-6-(3,5-DIMETHYLPHENYL)SULFONYLBENZONITRILE, HIV-1 RT, A-CHAIN, ... | 著者 | Ren, J, Stuart, D.I, Stammers, D.K. | 登録日 | 2001-07-16 | 公開日 | 2001-08-22 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | 2-Amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1. J.Med.Chem., 44, 2001
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2VUZ
| Crystal structure of Codakine in complex with biantennary nonasaccharide at 1.7A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CODAKINE, ... | 著者 | Gourdine, J.P, Cioci, G.C, Miguet, L, Unverzagt, C, Varrot, A, Gauthier, C, Smith-Ravin, E.J, Imberty, A. | 登録日 | 2008-06-02 | 公開日 | 2008-08-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | High Affinity Interaction between a Bivalve C-Type Lectin and a Biantennary Complex-Type N-Glycan Revealed by Crystallography and Microcalorimetry. J.Biol.Chem., 283, 2008
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3Q6F
| Crystal structure of Fab of human mAb 2909 specific for quaternary neutralizing epitope of HIV-1 gp120 | 分子名称: | DI(HYDROXYETHYL)ETHER, Heavy chain of Fab of human mAb 2909, Light chain of Fab of human mAb 2909 | 著者 | Spurrier, B, Sampson, J, Totrov, M, Li, H, O'Neal, T, William, C, Robinson, J, Gorny, M.K, Zolla-Pazner, S, Kong, X.P. | 登録日 | 2010-12-31 | 公開日 | 2011-05-25 | 最終更新日 | 2011-10-12 | 実験手法 | X-RAY DIFFRACTION (3.192 Å) | 主引用文献 | Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120. Structure, 19, 2011
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4B0S
| Structure of the Deamidase-Depupylase Dop of the Prokaryotic Ubiquitin-like Modification Pathway in Complex with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DEAMIDASE-DEPUPYLASE DOP, MAGNESIUM ION | 著者 | Ozcelik, D, Barandun, J, Schmitz, N, Sutter, M, Guth, E, Damberger, F.F, Allain, F.H.-T, Ban, N, Weber-Ban, E. | 登録日 | 2012-07-04 | 公開日 | 2012-09-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structures of Pup Ligase Pafa and Depupylase Dop from the Prokaryotic Ubiquitin-Like Modification Pathway. Nat.Commun., 3, 2012
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3O65
| Crystal structure of a Josephin-ubiquitin complex: Evolutionary restraints on ataxin-3 deubiquitinating activity | 分子名称: | Putative ataxin-3-like protein, SODIUM ION, Ubiquitin | 著者 | Weeks, S.D, Grasty, K.C, Hernandez-Cuebas, L, Loll, P.J. | 登録日 | 2010-07-28 | 公開日 | 2010-11-24 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structure of a Josephin-Ubiquitin Complex: EVOLUTIONARY RESTRAINTS ON ATAXIN-3 DEUBIQUITINATING ACTIVITY. J.Biol.Chem., 286, 2011
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1KAJ
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1ZDL
| Crystal Structure of Mouse Thioredoxin Reductase Type 2 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin reductase 2, ... | 著者 | Biterova, E.I, Turanov, A.A, Gladyshev, V.N, Barycki, J.J. | 登録日 | 2005-04-14 | 公開日 | 2005-11-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism. Proc.Natl.Acad.Sci.Usa, 102, 2005
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4BPQ
| Structure and substrate induced conformational changes of the secondary citrate-sodium symporter CitS revealed by electron crystallography | 分子名称: | CITRATE:SODIUM SYMPORTER | 著者 | Kebbel, F, Kurz, M, Arheit, M, Gruetter, M.G, Stahlberg, H. | 登録日 | 2013-05-27 | 公開日 | 2013-07-17 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (6 Å) | 主引用文献 | Structure and Substrate-Induced Conformational Changes of the Secondary Citrate/Sodium Symporter Cits Revealed by Electron Crystallography. Structure, 21, 2013
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1KAL
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3UBI
| The Absence of Tertiary Interactions in a Self-Assembled DNA Crystal Structure | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*CP*GP*TP*AP*CP*TP*CP*G)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*AP*GP*GP*CP*TP*GP*C)-3'), DNA (5'-D(P*CP*CP*GP*AP*GP*TP*AP*CP*GP*AP*CP*GP*AP*CP*AP*AP*G)-3'), ... | 著者 | Nguyen, N, Birktoft, J.J, Sha, R, Wang, T, Zheng, J, Constantinou, P.E, Ginell, S.L, Chen, Y, Mao, C, Seeman, N.C. | 登録日 | 2011-10-24 | 公開日 | 2012-05-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (6.8046 Å) | 主引用文献 | The absence of tertiary interactions in a self-assembled DNA crystal structure. J.Mol.Recognit., 25, 2012
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4DIN
| Novel Localization and Quaternary Structure of the PKA RI beta Holoenzyme | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... | 著者 | Ilouz, R, Bubis, J, Wu, J, Yim, Y.Y, Deal, M.S, Kornev, A.P, Ma, Y, Blumenthal, D.K, Taylor, S.S. | 登録日 | 2012-01-31 | 公開日 | 2012-07-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Localization and quaternary structure of the PKA RI Beta holoenzyme Proc.Natl.Acad.Sci.USA, 109, 2012
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1ZKQ
| Crystal structure of mouse thioredoxin reductase type 2 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase 2, mitochondrial | 著者 | Biterova, E.I, Turanov, A.A, Gladyshev, V.N, Barycki, J.J. | 登録日 | 2005-05-03 | 公開日 | 2005-11-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism. Proc.Natl.Acad.Sci.Usa, 102, 2005
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4B0R
| Structure of the Deamidase-Depupylase Dop of the Prokaryotic Ubiquitin-like Modification Pathway | 分子名称: | DEAMIDASE-DEPUPYLASE DOP | 著者 | Ozcelik, D, Barandun, J, Schmitz, N, Sutter, M, Guth, E, Damberger, F.F, Allain, F.H.-T, Ban, N, Weber-Ban, E. | 登録日 | 2012-07-04 | 公開日 | 2012-09-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structures of Pup ligase PafA and depupylase Dop from the prokaryotic ubiquitin-like modification pathway. Nat Commun, 3, 2012
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4OWK
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3OQ1
| Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor | 分子名称: | 3-(2-fluoroethyl)-4-({4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]phenyl}sulfonyl)benzonitrile, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Wang, Z, Sudom, A, Walker, N.P. | 登録日 | 2010-09-02 | 公開日 | 2011-07-20 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The synthesis and SAR of novel diarylsulfone 11beta-HSD1 inhibitors Bioorg.Med.Chem.Lett., 20, 2010
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4OWL
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4OWJ
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1JOK
| Averaged structure for Staphylococcal nuclease-H124L in ternary complex with Ca2+ and thymidine-3',5'-bisphosphate | 分子名称: | THYMIDINE-3',5'-DIPHOSPHATE, staphylococcal nuclease | 著者 | Wang, J, Truckses, D.M, Abildgaard, F, Dzakula, Z, Zolnai, Z, Markley, J.L. | 登録日 | 2001-07-30 | 公開日 | 2001-08-22 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of staphylococcal nuclease from multidimensional, multinuclear NMR: nuclease-H124L and its ternary complex with Ca2+ and thymidine-3',5'-bisphosphate. J.Biomol.NMR, 10, 1997
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1JOQ
| Ensemble structures for Staphylococcal nuclease-H124L in ternary complex with Ca2+ and thymidine-3',5'-bisphosphate | 分子名称: | THYMIDINE-3',5'-DIPHOSPHATE, staphylococcal nuclease | 著者 | Wang, J, Truckses, D.M, Abildgaard, F, Dzakula, Z, Zolnai, Z, Markley, J.L. | 登録日 | 2001-07-30 | 公開日 | 2001-08-22 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of staphylococcal nuclease from multidimensional, multinuclear NMR: nuclease-H124L and its ternary complex with Ca2+ and thymidine-3',5'-bisphosphate. J.Biomol.NMR, 10, 1997
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1HFP
| COMPARISON OF TERNARY CRYSTAL COMPLEXES OF HUMAN DIHYDROFOLATE REDUCTASE WITH NADPH AND A CLASSICAL ANTITUMOR FUROPYRIMDINE | 分子名称: | DIHYDROFOLATE REDUCTASE, N-[4-[(2,4-DIAMINOFURO[2,3D]PYRIMIDIN-5-YL)METHYL]METHYLAMINO]-BENZOYL]-L-GLUTAMATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Blakley, R.L, Gangjee, A. | 登録日 | 1997-11-04 | 公開日 | 1998-01-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine. Anti-Cancer Drug Des., 13, 1998
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1CD0
| STRUCTURE OF HUMAN LAMDA-6 LIGHT CHAIN DIMER JTO | 分子名称: | PROTEIN (JTO, A VARIABLE DOMAIN FROM LAMBDA-6 TYPE IMMUNOGLOBULIN LIGHT CHAIN) | 著者 | Pokkuluri, P.R, Solomon, A, Weiss, D.T, Stevens, F.J, Schiffer, M. | 登録日 | 1999-03-05 | 公開日 | 2000-03-06 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Tertiary structure of human lambda 6 light chains. Amyloid, 6, 1999
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1JUU
| NMR Structure of a Parallel Stranded DNA Duplex at Atomic Resolution | 分子名称: | 5'-D(P*CP*CP*AP*TP*AP*AP*TP*TP*TP*AP*CP*C)-3', 5'-D(P*CP*CP*TP*AP*TP*TP*AP*AP*AP*TP*CP*C)-3' | 著者 | Parvathy, V.R, Bhaumik, S.R, Chary, K.V.R, Govil, G, Liu, K, Howard, F.B, Miles, H.T. | 登録日 | 2001-08-28 | 公開日 | 2002-04-03 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of a parallel-stranded DNA duplex at atomic resolution. Nucleic Acids Res., 30, 2002
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1HFR
| COMPARISON OF TERNARY CRYSTAL COMPLEXES OF HUMAN DIHYDROFOLATE REDUCTASE WITH NADPH AND A CLASSICAL ANTITUMOR FUROPYRIMDINE | 分子名称: | DIHYDROFOLATE REDUCTASE, N-[4-[(2,4-DIAMINOFURO[2,3D]PYRIMIDIN-5-YL)METHYL]METHYLAMINO]-BENZOYL]-L-GLUTAMATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Blakley, R.L, Gangjee, A. | 登録日 | 1997-11-04 | 公開日 | 1998-01-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine. Anti-Cancer Drug Des., 13, 1998
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