8DY9
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3PED
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3L03
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![BU of 3l03 by Molmil](/molmil-images/mine/3l03) | Crystal Structure of human Estrogen Receptor alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II peptide and Estetrol (Estra-1,3,5(10)-triene-3,15 alpha,16alpha,17beta-tetrol) | 分子名称: | (14beta,15alpha,16alpha,17alpha)-estra-1,3,5(10)-triene-3,15,16,17-tetrol, CHLORIDE ION, Estrogen receptor, ... | 著者 | Rajan, S.S, Kim, Y, Vanek, K, Joachimiak, A, Greene, G.L. | 登録日 | 2009-12-09 | 公開日 | 2010-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.896 Å) | 主引用文献 | Crystal Structure of human Estrogen Receptor alpha Ligand-Binding Domain
in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II
peptide and Estra-1,3,5(10)-triene-3,15 alpha,16alpha,17beta-tetrol To be Published
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3PEC
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5NJB
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![BU of 5njb by Molmil](/molmil-images/mine/5njb) | E. coli Microcin-processing metalloprotease TldD/E with actinonin bound | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACTINONIN, ... | 著者 | Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K. | 登録日 | 2017-03-28 | 公開日 | 2017-10-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure, 25, 2017
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5OBH
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![BU of 5obh by Molmil](/molmil-images/mine/5obh) | Crystal structure of glycine binding protein in complex with bicuculline | 分子名称: | (5S)-6,6-dimethyl-5-[(6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl]-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Dawson, A, Hunter, W.N, Jones, M. | 登録日 | 2017-06-27 | 公開日 | 2018-08-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A Structural Rationale for N-Methylbicuculline Acting as a Promiscuous Competitive Antagonist of Inhibitory Pentameric Ligand-Gated Ion Channels. Chembiochem, 21, 2020
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8JE4
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![BU of 8je4 by Molmil](/molmil-images/mine/8je4) | Crystal structure of LimF prenyltransferase (H239G/W273T mutant) bound with the thiodiphosphate moiety of farnesyl S-thiolodiphosphate (FSPP) | 分子名称: | MAGNESIUM ION, TRIHYDROGEN THIODIPHOSPHATE, prenyltransferase, ... | 著者 | Hamada, K, Oguni, A, Zhang, Y, Satake, M, Goto, Y, Suga, H, Ogata, K, Sengoku, T. | 登録日 | 2023-05-15 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Switching Prenyl Donor Specificities of Cyanobactin Prenyltransferases. J.Am.Chem.Soc., 145, 2023
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3OV8
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![BU of 3ov8 by Molmil](/molmil-images/mine/3ov8) | Crystal structure of AF1382 from Archaeoglobus fulgidus, High resolution | 分子名称: | ACETATE ION, CHLORIDE ION, Protein AF_1382 | 著者 | Zhu, J.-Y, Zhao, M, Fu, Z.-Q, Yang, H, Chang, J, Hao, X, Chen, L, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2010-09-16 | 公開日 | 2011-11-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8501 Å) | 主引用文献 | Structure of the Archaeoglobus fulgidus orphan ORF AF1382 determined by sulfur SAD from a moderately diffracting crystal. Acta Crystallogr.,Sect.D, 68, 2012
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5DTR
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![BU of 5dtr by Molmil](/molmil-images/mine/5dtr) | Crystal structure of Dot1L in complex with inhibitor CPD5 [N-(2,6-dichlorophenyl)-4-methoxy-N-methylquinolin-6-amine] | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, N-(2,6-dichlorophenyl)-4-methoxy-N-methylquinolin-6-amine | 著者 | Scheufler, C, Be, C, Moebitz, H, Stauffer, F. | 登録日 | 2015-09-18 | 公開日 | 2016-06-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Optimization of a Fragment-Based Screening Hit toward Potent DOT1L Inhibitors Interacting in an Induced Binding Pocket. Acs Med.Chem.Lett., 7, 2016
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3KCP
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![BU of 3kcp by Molmil](/molmil-images/mine/3kcp) | Crystal structure of interacting Clostridium thermocellum multimodular components | 分子名称: | CALCIUM ION, CHLORIDE ION, Cellulosomal-scaffolding protein A, ... | 著者 | Adams, J.J, Currie, M.A, Bayer, E.A, Jia, Z, Smith, S.P. | 登録日 | 2009-10-21 | 公開日 | 2010-02-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Insights into Higher-Order Organization of the Cellulosome Revealed by a Dissect-and-Build Approach: Crystal Structure of Interacting Clostridium thermocellum Multimodular Components J.Mol.Biol., 396, 2010
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3O83
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![BU of 3o83 by Molmil](/molmil-images/mine/3o83) | Structure of BasE N-terminal domain from Acinetobacter baumannii bound to 2-(4-n-dodecyl-1,2,3-triazol-1-yl)-5'-O-[N-(2-hydroxybenzoyl)sulfamoyl]adenosine | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(4-dodecyl-1H-1,2,3-triazol-1-yl)-5'-O-{[(2-hydroxyphenyl)carbonyl]sulfamoyl}adenosine, ... | 著者 | Drake, E.J, Duckworth, B.P, Neres, J, Aldrich, C.C, Gulick, A.M. | 登録日 | 2010-08-02 | 公開日 | 2010-10-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Biochemical and structural characterization of bisubstrate inhibitors of BasE, the self-standing nonribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis. Biochemistry, 49, 2010
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3O3K
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![BU of 3o3k by Molmil](/molmil-images/mine/3o3k) | Crystal structure of AF1382 from Archaeoglobus fulgidus | 分子名称: | Uncharacterized protein AF_1382 | 著者 | Zhu, J.-Y, Zhao, M, Fu, Z.-Q, Yang, H, Chang, J, Xu, H, Chen, L, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2010-07-24 | 公開日 | 2010-08-04 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Archaeoglobus fulgidus orphan ORF AF1382 determined by sulfur SAD from a moderately diffracting crystal. Acta Crystallogr.,Sect.D, 68, 2012
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1KPE
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![BU of 1kpe by Molmil](/molmil-images/mine/1kpe) | PKCI-TRANSITION STATE ANALOG | 分子名称: | ADENOSINE-5'-DITUNGSTATE, PROTEIN KINASE C INTERACTING PROTEIN | 著者 | Lima, C.D, Klein, M.G, Hendrickson, W.A. | 登録日 | 1997-09-25 | 公開日 | 1998-03-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science, 278, 1997
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3O84
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![BU of 3o84 by Molmil](/molmil-images/mine/3o84) | Structure of BasE N-terminal domain from Acinetobacter baumannii bound to 6-phenyl-1-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid. | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 6-phenyl-1-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid, ... | 著者 | Drake, E.J, Duckworth, B.P, Neres, J, Aldrich, C.C, Gulick, A.M. | 登録日 | 2010-08-02 | 公開日 | 2010-10-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Biochemical and structural characterization of bisubstrate inhibitors of BasE, the self-standing nonribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis. Biochemistry, 49, 2010
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3O82
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![BU of 3o82 by Molmil](/molmil-images/mine/3o82) | Structure of BasE N-terminal domain from Acinetobacter baumannii bound to 5'-O-[N-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine | 分子名称: | 5'-O-{[(2,3-dihydroxyphenyl)carbonyl]sulfamoyl}adenosine, CALCIUM ION, Peptide arylation enzyme | 著者 | Drake, E.J, Duckworth, B.P, Neres, J, Aldrich, C.C, Gulick, A.M. | 登録日 | 2010-08-02 | 公開日 | 2010-10-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Biochemical and structural characterization of bisubstrate inhibitors of BasE, the self-standing nonribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis. Biochemistry, 49, 2010
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1B77
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1PD7
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![BU of 1pd7 by Molmil](/molmil-images/mine/1pd7) | Extended SID of Mad1 bound to the PAH2 domain of mSin3B | 分子名称: | Mad1, Sin3b protein | 著者 | Van Ingen, H, Lasonder, E, Jansen, J.F, Kaan, A.M, Spronk, C.A, Stunnenberg, H.G, Vuister, G.W. | 登録日 | 2003-05-19 | 公開日 | 2004-01-20 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Extension of the binding motif of the sin3 interacting domain of the mad family proteins(,). Biochemistry, 43, 2004
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1AV5
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![BU of 1av5 by Molmil](/molmil-images/mine/1av5) | PKCI-SUBSTRATE ANALOG | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, PROTEIN KINASE C INTERACTING PROTEIN | 著者 | Lima, C.D, Klein, M.G, Hendrickson, W.A. | 登録日 | 1997-09-25 | 公開日 | 1998-03-25 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science, 278, 1997
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3C87
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![BU of 3c87 by Molmil](/molmil-images/mine/3c87) | Crystal structure of the enterobactin esterase FES from Shigella flexneri in the presence of enterobactin | 分子名称: | Enterochelin esterase, PHOSPHATE ION, SODIUM ION | 著者 | Kim, Y, Maltseva, N, Abergel, R, Raymond, K, Holzle, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-02-11 | 公開日 | 2008-02-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Siderophore Mediated Iron Acquisition: Structure and Specificity of Enterobactin Esterase from Shigella flexneri. To be Published
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3C8H
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![BU of 3c8h by Molmil](/molmil-images/mine/3c8h) | Crystal structure of the enterobactin esterase FES from Shigella flexneri in the presence of 2,3-Di-hydroxy-N-benzoyl-serine | 分子名称: | Enterochelin esterase | 著者 | Kim, Y, Maltseva, N, Abergel, R, Holzle, D, Raymond, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-02-12 | 公開日 | 2008-02-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Siderophore Mediated Iron Acquisition: Structure and Specificity of Enterobactin Esterase from Shigella flexneri. To be Published
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1RY1
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![BU of 1ry1 by Molmil](/molmil-images/mine/1ry1) | Structure of the signal recognition particle interacting with the elongation-arrested ribosome | 分子名称: | SRP Alu domain, SRP RNA, SRP S domain, ... | 著者 | Halic, M, Becker, T, Pool, M.R, Spahn, C.M, Grassucci, R.A, Frank, J, Beckmann, R. | 登録日 | 2003-12-19 | 公開日 | 2004-04-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | Structure of the signal recognition particle interacting with the elongation-arrested ribosome Nature, 427, 2004
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8A1N
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![BU of 8a1n by Molmil](/molmil-images/mine/8a1n) | Crystal structure of the transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with fumaryl amide analogue 13 | 分子名称: | (Z)-N-(4-chlorophenyl)-4-oxidanylidene-but-2-enamide, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | 著者 | de Munnik, M, Lang, P.A, Brem, J, Schofield, C.J. | 登録日 | 2022-06-01 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | High-throughput screen with the l,d-transpeptidase Ldt Mt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors. Chem Sci, 14, 2023
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8A1M
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![BU of 8a1m by Molmil](/molmil-images/mine/8a1m) | Crystal structure of the transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with maleimide analogue 4 | 分子名称: | 1,2-ETHANEDIOL, 1-(2-fluoranyl-5-methylsulfonyl-phenyl)pyrrolidine-2,5-dione, CHLORIDE ION, ... | 著者 | de Munnik, M, Lang, P.A, Brem, J, Schofield, C.J. | 登録日 | 2022-06-01 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | High-throughput screen with the l,d-transpeptidase Ldt Mt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors. Chem Sci, 14, 2023
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8A1K
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![BU of 8a1k by Molmil](/molmil-images/mine/8a1k) | Crystal structure of the transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with ebsulfur analogue 15 | 分子名称: | 1,2-ETHANEDIOL, 4,5-bis(chloranyl)-N-(2-hydroxyethyl)-2-sulfanyl-benzamide, DIMETHYL SULFOXIDE, ... | 著者 | de Munnik, M, Lang, P.A, Brem, J, Schofield, C.J. | 登録日 | 2022-06-01 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | High-throughput screen with the l,d-transpeptidase Ldt Mt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors. Chem Sci, 14, 2023
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8A1O
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![BU of 8a1o by Molmil](/molmil-images/mine/8a1o) | Crystal structure of the transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with acrylamide analogue 8 | 分子名称: | (E)-3-chloranyl-3-[(2-chlorophenyl)methylsulfonyl]-N-(5-methoxypyridin-2-yl)prop-2-enamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | de Munnik, M, Lang, P.A, Brem, J, Schofield, C.J. | 登録日 | 2022-06-01 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | High-throughput screen with the l,d-transpeptidase Ldt Mt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors. Chem Sci, 14, 2023
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