3PED

Siderocalin Recognitin of Carboxymycobactins: Interference by the immune system in intracellular iron acquisition by Mycobacteria tuberculosis

Summary for 3PED

• Entry DOI: 10.2210/pdb3ped/pdb
• Related: 1X89 1X8U 3PEC
• Descriptor: Neutrophil gelatinase-associated lipocalin, FE (III) ION, (9Z)-11-{hydroxy[(5S)-6-{[(1S)-3-{[(3S)-1-hydroxy-2-oxoazepan-3-yl]amino}-1-methyl-3-oxopropyl]oxy}-5-({[(4S)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-oxazol-4-yl]carbonyl}amino)-6-oxohexyl]amino}-11-oxoundec-9-enoic acid, ... (5 entities in total)
• Functional Keywords: 8-stranded anti-parallel beta barrel, siderocalin, siderophore binding, antimicrobial protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P80188
• Total number of polymer chains: 3
• Total formula weight: 64212.44

Authors

Clifton, M.C. (deposition date: 2010-10-25, release date: 2011-10-05, Last modification date: 2023-09-06)

• Primary citation: Hoette, T.M.,Clifton, M.C.,Zawadzka, A.M.,Holmes, M.A.,Strong, R.K.,Raymond, K.R.; Siderocalin Recognitin of Carboxymycobactins: Interference by the immune system in intracellular iron acquisition by Mycobacteria tuberculosis; To be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)