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1K8P
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Structure of the Human G-quadruplex reveals a novel topology
分子名称: 5'-D(*(BRU)P*AP*GP*GP*GP*(BRU)P*TP*AP*GP*GP*GP*T)-3', POTASSIUM ION, SODIUM ION
著者Parkinson, G.N, Lee, M.P.H, Neidle, S.
登録日2001-10-25
公開日2002-05-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of parallel quadruplexes from human telomeric DNA.
Nature, 417, 2002
5UA3
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Crystal Structure of a DNA G-Quadruplex with a Cytosine Bulge
分子名称: DNA (5'-D(*GP*GP*GP*TP*TP*GP*CP*GP*GP*AP*GP*GP*GP*TP*GP*GP*GP*CP*CP*T)-3'), POTASSIUM ION
著者Meier, M, McDougall, M.D, Krahn, N.J, Moya-Torres, A, McRae, E.K.S, Booy, E.P, Patel, T.R, McKenna, S.A, Stetefeld, J.
登録日2016-12-18
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8802 Å)
主引用文献Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge.
Nucleic Acids Res., 46, 2018
2AVJ
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G4(Br)UTTG4 dimeric quadruplex
分子名称: 5'-D(*GP*GP*GP*GP*(BRU)P*TP*TP*GP*GP*GP*G)-3', CACODYLATE ION, POTASSIUM ION
著者Hazel, P, Parkinson, G.N, Neidle, S.
登録日2005-08-30
公開日2006-03-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Topology variation and loop structural homology in crystal and simulated structures of a bimolecular DNA quadruplex.
J.Am.Chem.Soc., 128, 2006
1JVC
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Dimeric DNA Quadruplex Containing Major Groove-Aligned A.T.A.T and G.C.G.C Tetrads Stabilized by Inter-Subunit Watson-Crick A:T and G:C Pairs
分子名称: 5'-D(*GP*AP*GP*CP*AP*GP*GP*T)-3'
著者Zhang, N, Gorin, A, Majumdar, A, Kettani, A, Chernichenko, N, Skripkin, E, Patel, D.J.
登録日2001-08-29
公開日2001-10-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Dimeric DNA quadruplex containing major groove-aligned A-T-A-T and G-C-G-C tetrads stabilized by inter-subunit Watson-Crick A-T and G-C pairs.
J.Mol.Biol., 312, 2001
2AVH
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G4T3G4 dimeric quadruplex structure
分子名称: 5'-D(*GP*GP*GP*GP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
著者Hazel, P, Parkinson, G.N, Neidle, S.
登録日2005-08-30
公開日2006-03-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Topology variation and loop structural homology in crystal and simulated structures of a bimolecular DNA quadruplex.
J.Am.Chem.Soc., 128, 2006
6ZX6
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Antiparallel basket-type G-quadruplex DNA structure formed in human Bcl-2 promoter containing 8-oxoG
分子名称: bcl2ex-oxoG19
著者Bielskute, S, Plavec, J, Podbevsek, P.
登録日2020-07-29
公開日2021-03-10
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Oxidative lesions modulate G-quadruplex stability and structure in the human BCL2 promoter.
Nucleic Acids Res., 49, 2021
6ZX7
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Antiparallel basket-type G-quadruplex DNA structure formed in human Bcl-2 promoter
分子名称: bcl2ex
著者Bielskute, S, Plavec, J, Podbevsek, P.
登録日2020-07-29
公開日2021-03-10
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Oxidative lesions modulate G-quadruplex stability and structure in the human BCL2 promoter.
Nucleic Acids Res., 49, 2021
1MYQ
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An intramolecular quadruplex of (GGA)(4) triplet repeat DNA with a G:G:G:G tetrad and a G(:A):G(:A):G(:A):G heptad, and its dimeric interaction
分子名称: 5'-D(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3'
著者Matsugami, A, Ouhashi, K, Kanagawa, M, Liu, H, Kanagawa, S, Uesugi, S, Katahira, M.
登録日2002-10-04
公開日2002-10-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献An intramolecular quadruplex of (GGA)(4) triplet repeat DNA with a G:G:G:G tetrad and a G(:A):G(:A):G(:A):G heptad, and its dimeric interaction.
J.Mol.Biol., 313, 2001
139D
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SOLUTION STRUCTURE OF A PARALLEL-STRANDED G-QUADRUPLEX DNA
分子名称: DNA (5'-D(*TP*TP*GP*GP*GP*GP*T)-3')
著者Patel, D.J, Wang, Y.
登録日1993-09-28
公開日1994-01-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a parallel-stranded G-quadruplex DNA.
J.Mol.Biol., 234, 1993
1VYA
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Identification and characterization of the first plant G-quadruplex binding protein encoded by the Zea mays L. nucleoside diphosphate1 gene, ZmNDPK1
分子名称: Nucleoside diphosphate kinase
著者Kopylov, M, Stroupe, M.E.
登録日2014-08-14
公開日2015-04-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Maize (Zea mays L.) Nucleoside Diphosphate Kinase1 (ZmNDPK1) Gene Encodes a Human NM23-H2 Homologue That Binds and Stabilizes G-Quadruplex DNA.
Biochemistry, 54, 2015
8C7A
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Slow cation movements within tetramolecular G-quadruplex: vacant cation binding sites in addition to all syn G-quartet
分子名称: DNA (5'-D(*GP*GP*GP*GP*CP*C)-3')
著者Wang, B, Zalar, M, Plavec, J, Sket, P.
登録日2023-01-14
公開日2023-11-22
実験手法SOLUTION NMR
主引用文献Insight into Tetramolecular DNA G-Quadruplexes Associated with ALS and FTLD: Cation Interactions and Formation of Higher-Ordered Structure.
Int J Mol Sci, 24, 2023
8S1W
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Structure of a quadruplex-duplex hybrid with a (-pd+l) loop progression
分子名称: DNA (33-MER)
著者Vianney, Y.M, Jana, J, Weisz, K.
登録日2024-02-16
公開日2024-03-27
最終更新日2024-06-05
実験手法SOLUTION NMR
主引用文献A pH-Responsive Topological Switch Based on a DNA Quadruplex-Duplex Hybrid.
Chemistry, 30, 2024
8RW2
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Structure of a chair-type antiparallel quadruplex-duplex hybrid at pH 6
分子名称: DNA (33-MER)
著者Vianney, Y.M, Weisz, K.
登録日2024-02-02
公開日2024-03-27
最終更新日2024-06-05
実験手法SOLUTION NMR
主引用文献A pH-Responsive Topological Switch Based on a DNA Quadruplex-Duplex Hybrid.
Chemistry, 30, 2024
6XRQ
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Structural descriptions of ligand interactions to DNA and RNA quadruplexes folded from the non-coding region of Pseudorabies virus
分子名称: 2,7-bis[3-(morpholin-4-yl)propyl]-4,9-bis{[3-(morpholin-4-yl)propyl]amino}benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, POTASSIUM ION, RNA (5' GP*GP*CP*UP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A-3')
著者Zhang, Y.S, Parkinson, G.N, Wei, D.G.
登録日2020-07-13
公開日2021-07-28
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Structural descriptions of ligand interactions to RNA quadruplexes folded from the non-coding region of Pseudorabies virus.
Biochimie, 2024
6M05
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Trimolecular G-quadruplex
分子名称: DNA (5'-D(*GP*TP*TP*AP*GP*G)-3')
著者Jing, H.T, Fu, W.Q, Zhang, N.
登録日2020-02-20
公開日2021-01-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structural study on the self-trimerization of d(GTTAGG) into a dynamic trimolecular G-quadruplex assembly preferentially in Na+ solution with a moderate K+ tolerance.
Nucleic Acids Res., 49, 2021
6FC9
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The 1,8-bis(aminomethyl)anthracene and Quadruplex-duplex junction complex
分子名称: DNA (27-MER), [8-(azaniumylmethyl)anthracen-1-yl]methylazanium
著者Santana, A, Serrano, I, Montalvillo-Jimenez, L, Corzana, F, Bastida, A, Jimenez-Barbero, J, Gonzalez, C, Asensio, J.L.
登録日2017-12-20
公開日2019-04-10
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献De Novo Design of Selective Quadruplex-Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot.
Chemistry, 2020
6CRM
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Crystal Structure of RecQ catalytic core from C. sakazakii bound to an unfolded G-quadruplex
分子名称: DNA (5'-D(P*GP*GP*GP*TP*CP*GP*GP*TP*GP*CP*CP*TP*TP*A)-3'), RecQ, ZINC ION
著者Voter, A.F, Keck, J.L.
登録日2018-03-19
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.19286251 Å)
主引用文献A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases.
Nat Commun, 9, 2018
6O2L
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NMR structure of the 2:1 complex of a carbazole derivative BMVC bound to c-MYC G-quadruplex
分子名称: 3,6-bis[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]-9H-carbazole, DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3')
著者Lin, C, Liu, W, Yang, D.
登録日2019-02-24
公開日2019-10-23
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition.
Nucleic Acids Res., 47, 2019
5J4P
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DIY G-Quadruplexes: Solution structure of d(GGTTTGGTTTTGGTTTGG) in sodium
分子名称: DNA (5'-D(*GP*GP*TP*TP*TP*GP*GP*TP*TP*TP*TP*GP*GP*TP*TP*TP*GP*G)-3')
著者Dvorkin, S.A, Webba da Silva, M.
登録日2016-04-01
公開日2017-06-14
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Encoding canonical DNA quadruplex structure.
Sci Adv, 4, 2018
5J4W
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DIY G-Quadruplexes: Solution structure of d(GGTTTGGTTTTGGTTGG) in sodium
分子名称: DNA (5'-D(*GP*GP*TP*TP*TP*GP*GP*TP*TP*TP*TP*GP*GP*TP*TP*GP*G)-3')
著者Dvorkin, S.A, Webba da Silva, M.
登録日2016-04-01
公開日2017-04-12
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Encoding canonical DNA quadruplex structure.
Sci Adv, 4, 2018
1JJP
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A(GGGG) Pentad-Containing Dimeric DNA Quadruplex Involving Stacked G(anti)G(anti)G(anti)G(syn) Tetrads
分子名称: 5'-D(*GP*GP*GP*AP*GP*GP*TP*TP*TP*GP*GP*GP*AP*T)-3'
著者Zhang, N, Gorin, A, Majumdar, A, Kettani, A, Chernichenko, N, Skripkin, E, Patel, D.J.
登録日2001-07-09
公開日2001-09-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献V-shaped scaffold: a new architectural motif identified in an A x (G x G x G x G) pentad-containing dimeric DNA quadruplex involving stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads.
J.Mol.Biol., 311, 2001
1L1H
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Crystal Structure of the Quadruplex DNA-Drug Complex
分子名称: 3-PYRROLIDIN-1-YL-N-[6-(3-PYRROLIDIN-1-YL-PROPIONYLAMINO)-ACRIDIN-3-YL]-PROPIONAMIDE, 5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
著者Haider, S.M, Parkinson, G.N, Neidle, S.
登録日2002-02-16
公開日2003-02-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of a G-quadruplex-Ligand Complex
J.Mol.Biol., 326, 2003
1MY9
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Solution structure of a K+ cation stabilized dimeric RNA quadruplex containing two G:G(:A):G:G(:A) hexads, G:G:G:G tetrads and UUUU loops
分子名称: 5'-R(*GP*GP*AP*GP*GP*UP*UP*UP*UP*GP*GP*AP*GP*G)-3'
著者Liu, H, Matsugami, A, Katahira, M, Uesugi, S.
登録日2002-10-04
公開日2003-10-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A Dimeric RNA Quadruplex Architecture Comprised of Two G:G(:A):G:G(:A) Hexads, G:G:G:G Tetrads and UUUU Loops
J.Mol.Biol., 322, 2002
2HY9
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Human telomere DNA quadruplex structure in K+ solution hybrid-1 form
分子名称: DNA (26-MER)
著者Dai, J, Punchihewa, C, Jones, R.A, Hurley, L, Yang, D.
登録日2006-08-04
公開日2007-04-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation.
Nucleic Acids Res., 35, 2007
7KBV
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Solution structure of the major MYC promoter G-quadruplex with a wild-type flanking sequence
分子名称: Myc2345
著者Dickerhoff, J, Yang, D.
登録日2020-10-03
公開日2021-06-23
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes.
Nucleic Acids Res., 49, 2021

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件を2024-08-28に公開中

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