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2EWN
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Ecoli Biotin Repressor with co-repressor analog
分子名称: ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, BirA bifunctional protein
著者Wood, Z.A, Weaver, L.H, Matthews, B.W.
登録日2005-11-04
公開日2006-02-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Co-repressor Induced Order and Biotin Repressor Dimerization: A Case for Divergent Followed by Convergent Evolution.
J.Mol.Biol., 357, 2006
4B3A
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Tetracycline repressor class D mutant H100A in complex with tetracycline
分子名称: CHLORIDE ION, MAGNESIUM ION, TETRACYCLINE, ...
著者Eltschkner, S, Schindler, S, Palm, G.J, Schneider, J, Hinrichs, W.
登録日2012-07-23
公開日2013-06-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
1DDN
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DIPHTHERIA TOX REPRESSOR (C102D MUTANT)/TOX DNA OPERATOR COMPLEX
分子名称: 33 BASE DNA CONTAINING TOXIN OPERATOR, DIPHTHERIA TOX REPRESSOR, NICKEL (II) ION
著者White, A, Ding, X, Vanderspek, J.C, Murphy, J.R, Ringe, D.
登録日1998-06-23
公開日1998-10-14
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex.
Nature, 394, 1998
2X9D
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Tet repressor (class D) in complex with iso-7-chlortetracycline
分子名称: CHLORIDE ION, ISO-7-CHLORTETRACYCLINE, TETRACYCLINE REPRESSOR PROTEIN CLASS D
著者Volkers, G, Hinrichs, W.
登録日2010-03-15
公開日2011-03-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Recognition of Drug Degradation Products by Target Proteins: Isotetracycline Binding to Tet Repressor.
J.Med.Chem., 54, 2011
2X6O
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Tet Repressor class D in complex with 7-chlor-2-cyano-iso- tetracycline
分子名称: (4S,4AS,6S,8AS)-6-[(1S)-7-CHLORO-4-HYDROXY-1-METHYL-3-OXO-1,3-DIHYDRO-2-BENZOFURAN-1-YL]-4-(DIMETHYLAMINO)-3,8A-DIHYDROXY-1,8-DIOXO-1,4,4A,5,6,7,8,8A-OCTAHYDRONAPHTHALENE-2-CARBONITRILE, CHLORIDE ION, TETRACYCLINE REPRESSOR PROTEIN CLASS D
著者Volkers, G, Hinrichs, W.
登録日2010-02-18
公開日2011-03-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Recognition of Drug Degradation Products by Target Proteins: Isotetracycline Binding to Tet Repressor.
J.Med.Chem., 54, 2011
1C0W
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CRYSTAL STRUCTURE OF THE COBALT-ACTIVATED DIPHTHERIA TOXIN REPRESSOR-DNA COMPLEX REVEALS A METAL BINDING SH-LIKE DOMAIN
分子名称: COBALT (II) ION, DIPHTHERIA TOXIN REPRESSOR, DNA (5'-D(P*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*CP*CP*TP*AP*CP*CP*CP*TP*AP*AP*T)-3'), ...
著者Pohl, E, Holmes, R.K, Hol, W.G.
登録日1999-07-22
公開日2000-07-22
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain.
J.Mol.Biol., 292, 1999
3CAG
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Crystal structure of the oligomerization domain hexamer of the arginine repressor protein from Mycobacterium tuberculosis in complex with 9 arginines.
分子名称: ARGININE, Arginine repressor
著者Cherney, L.T, Cherney, M.M, Garen, C.R, Lu, G.J, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2008-02-19
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 64, 2008
2VPR
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Tet repressor class H in complex with 5a,6- anhydrotetracycline-Mg
分子名称: 5A,6-ANHYDROTETRACYCLINE, MAGNESIUM ION, SULFATE ION, ...
著者Schuldt, L, Palm, G, Hinrichs, W.
登録日2008-03-03
公開日2008-03-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Tet Repressor Induction by Tetracycline: A Molecular Dynamics, Continuum Electrostatics, and Crystallographic Study
J.Mol.Biol., 378, 2008
2HO0
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Structure of a Hyper-cleavable Monomeric Fragment of Phage Lambda Repressor Containing the Cleavage Site Region
分子名称: CALCIUM ION, Repressor protein cI101-229DM-K192A
著者Ndjonka, D, Bell, C.E.
登録日2006-07-13
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of a Hyper-cleavable Monomeric Fragment of Phage lambda Repressor Containing the Cleavage Site Region.
J.Mol.Biol., 362, 2006
2HNF
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Structure of a Hyper-cleavable Monomeric Fragment of Phage lambda Repressor Containing the Cleavage Site Region
分子名称: CALCIUM ION, Repressor protein cI101-229DM-K192A
著者Ndjonka, D, Bell, C.E.
登録日2006-07-12
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a Hyper-cleavable Monomeric Fragment of Phage lambda Repressor Containing the Cleavage Site Region.
J.Mol.Biol., 362, 2006
2FJ1
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Crystal Structure Analysis of Tet Repressor (class D) in Complex with 7-Chlortetracycline-Nickel(II)
分子名称: 7-CHLOROTETRACYCLINE, CHLORIDE ION, NICKEL (II) ION, ...
著者Orth, P, Saenger, W, Palm, G.J, Hinrichs, W.
登録日2005-12-30
公開日2007-01-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Specific binding of divalent metal ions to tetracycline and to the Tet repressor/tetracycline complex.
J.Biol.Inorg.Chem., 13, 2008
1KKQ
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Crystal structure of the human PPAR-alpha ligand-binding domain in complex with an antagonist GW6471 and a SMRT corepressor motif
分子名称: N-((2S)-2-({(1Z)-1-METHYL-3-OXO-3-[4-(TRIFLUOROMETHYL) PHENYL]PROP-1-ENYL}AMINO)-3-{4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL}PROPYL)PROPANAMIDE, NUCLEAR RECEPTOR CO-REPRESSOR 2, PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR
著者Xu, H.E, Stanley, T.B, Montana, V.G, Lambert, M.H, Shearer, B.G, Cobb, J.E, McKee, D.D, Galardi, C.M, Nolte, R.T, Parks, D.J.
登録日2001-12-10
公開日2002-02-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha.
Nature, 415, 2002
1A6I
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TET REPRESSOR, CLASS D VARIANT
分子名称: TETRACYCLINE REPRESSOR PROTEIN CLASS D
著者Orth, P, Cordes, F, Schnappinger, D, Hillen, W, Saenger, W, Hinrichs, W.
登録日1998-02-25
公開日1999-03-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational changes of the Tet repressor induced by tetracycline trapping.
J.Mol.Biol., 279, 1998
1MJO
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METHIONINE HOLOREPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO THE MINIMAL MET CONSENSUS OPERATOR WITH THE CENTRAL TA STEP MUTATED TO AT
分子名称: CALCIUM ION, CONSENSUS DNA OPERATOR DUPLEX WITH THE CENTRAL TA STEP MUTATED TO AT, METHIONINE REPRESSOR, ...
著者Garvie, C.W, Phillips, S.E.V.
登録日1998-01-28
公開日1999-08-02
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Direct and indirect readout in mutant Met repressor-operator complexes.
Structure Fold.Des., 8, 2000
1MJQ
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METHIONINE REPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO AN ALTERED MET CONSENSUS OPERATOR SEQUENCE
分子名称: METHIONINE REPRESSOR, MUTATED MET CONSENSUS OPERATOR DUPLEX, S-ADENOSYLMETHIONINE
著者Garvie, C.W, Phillips, S.E.V.
登録日1998-01-30
公開日1999-08-02
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Direct and indirect readout in mutant Met repressor-operator complexes.
Structure Fold.Des., 8, 2000
1MJM
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METHIONINE APOREPRESSOR MUTANT (Q44K) COMPLEXED TO HALF OF THE CONSENSUS OPERATOR SEQUENCE
分子名称: HALF CONSENSUS DNA OPERATOR DUPLEX, METHIONINE REPRESSOR
著者Garvie, C.W, Phillips, S.E.V.
登録日1998-01-30
公開日1999-08-02
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Direct and indirect readout in mutant Met repressor-operator complexes.
Structure Fold.Des., 8, 2000
1MI7
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Crystal Structure of Domain Swapped trp Aporepressor in 30%(v/v) Isopropanol
分子名称: ISOPROPYL ALCOHOL, Trp operon repressor
著者Lawson, C.L, Benoff, B, Berger, T, Berman, H.M, Carey, J.
登録日2002-08-22
公開日2003-09-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献E. coli trp repressor forms a domain-swapped array in aqueous alcohol.
Structure, 12, 2004
5ZZ6
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Redox-sensing transcriptional repressor Rex
分子名称: ADENOSINE-5'-DIPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Redox-sensing transcriptional repressor Rex 1
著者Park, Y.W, Jang, Y.Y, Joo, H.K, Lee, J.Y.
登録日2018-05-30
公開日2018-11-07
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Analysis of Redox-sensing Transcriptional Repressor Rex from Thermotoga maritima
Sci Rep, 8, 2018
3GBP
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STRUCTURE OF THE PERIPLASMIC GLUCOSE/GALACTOSE RECEPTOR OF SALMONELLA TYPHIMURIUM
分子名称: CALCIUM ION, GALACTOSE-BINDING PROTEIN, beta-D-glucopyranose
著者Mowbray, S.L.
登録日1990-01-25
公開日1991-07-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the periplasmic glucose/galactose receptor of Salmonella typhimurium.
Receptor, 1, 1990
4M1P
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Crystal structure of the copper-sensing repressor CsoR with Cu(I) from Geobacillus thermodenitrificans NG80-2
分子名称: COPPER (I) ION, Copper-sensitive operon repressor (CsoR), SODIUM ION
著者Chang, F, Dann III, C.E, Giedroc, D.P.
登録日2013-08-03
公開日2014-05-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.564 Å)
主引用文献Cu(I)-mediated allosteric switching in a copper-sensing operon repressor (CsoR).
J.Biol.Chem., 289, 2014
5ZZ7
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Redox-sensing transcriptional repressor Rex
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, Redox-sensing transcriptional repressor Rex 1
著者Park, Y.W, Jang, Y.Y, Joo, H.K, Lee, J.Y.
登録日2018-05-30
公開日2018-11-07
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural Analysis of Redox-sensing Transcriptional Repressor Rex from Thermotoga maritima
Sci Rep, 8, 2018
1MYK
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CRYSTAL STRUCTURE, FOLDING, AND OPERATOR BINDING OF THE HYPERSTABLE ARC REPRESSOR MUTANT PL8
分子名称: ARC REPRESSOR
著者Schildbach, J.F, Milla, M.E, Jeffrey, P.D, Raumann, B.E, Sauer, R.T.
登録日1994-10-12
公開日1995-01-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure, folding, and operator binding of the hyperstable Arc repressor mutant PL8.
Biochemistry, 34, 1995
5ZZ5
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Redox-sensing transcriptional repressor Rex
分子名称: GLYCEROL, Redox-sensing transcriptional repressor Rex
著者Park, Y.W, Jang, Y.Y, Joo, H.K, Lee, J.Y.
登録日2018-05-30
公開日2018-11-07
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of Redox-sensing Transcriptional Repressor Rex from Thermotoga maritima
Sci Rep, 8, 2018
3TB6
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Structure of the effector-binding domain of arabinose repressor AraR from Bacillus subtilis
分子名称: Arabinose metabolism transcriptional repressor, GLYCEROL, beta-L-arabinopyranose
著者Rezacova, P, Prochazkova, K.
登録日2011-08-05
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structure of the effector-binding domain of the arabinose repressor AraR from Bacillus subtilis.
Acta Crystallogr.,Sect.D, 68, 2012
1IRQ
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Crystal structure of omega transcriptional repressor at 1.5A resolution
分子名称: omega transcriptional repressor
著者Murayama, K, Orth, P, De La Hoz, A.B, Alonso, J.C, Saenger, W.
登録日2001-10-11
公開日2001-12-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of omega transcriptional repressor encoded by Streptococcus pyogenes plasmid pSM19035 at 1.5 A resolution.
J.Mol.Biol., 314, 2001

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