PDB: 491 件ウェブページステータス検索Chemie searchBIRD

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3ZIP	minor-site specific NLS (A58) 分子名称: A58NLS, IMPORTIN SUBUNIT ALPHA-2 著者 Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. 登録日 2013-01-10 公開日 2013-08-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha Traffic, 14, 2013
8GAI	Cavia porcellus (guinea pig) importin-alpha 1 in complex with Bimax2 peptide 分子名称: Bimax2, Importin subunit alpha 著者 Hawker, J.E, Forwood, J.K, Donnelly, C.M, Stewart, M. 登録日 2023-02-22 公開日 2023-04-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in complex with bimax2 peptide To Be Published
8FZK	Dimeric human importin alpha subunit 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Importin subunit alpha-1, MAGNESIUM ION 著者 Donnelly, C.M, Stewart, M, Forwood, J.K. 登録日 2023-01-29 公開日 2023-02-08 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Dimeric human importin alpha subunit To Be Published
4E4V	The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution. 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Importin subunit alpha-2 著者 Hang, P.C, Miknis, Z.M, Franke, W.A, Umland, T.C, Schultz, L.W. 登録日 2012-03-13 公開日 2013-05-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5283 Å) 主引用文献 The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution. To be Published
8G8R	RelB NLS in complex with Importin alpha 2 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Importin subunit alpha-1, Transcription factor RelB 著者 Tsimbslyuk, S, Stewart, M, Forwood, J.K. 登録日 2023-02-19 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 monopartite p52 NLS in complex with Importin alpha 2 To Be Published
2X1G	Crystal structure of Importin13 - Mago-Y14 complex 分子名称: CADMUS, PROTEIN MAGO NASHI, RNA-BINDING PROTEIN 8A 著者 Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E. 登録日 2009-12-23 公開日 2010-02-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13. Mol.Cell, 37, 2010
3WPT	Crystal structure of closed dimer of human importin-alpha1 (Rch1) 分子名称: DI(HYDROXYETHYL)ETHER, Importin subunit alpha-1 著者 Miyatake, H, Sanjoh, A, Matsuda, G, Tatsumi, Y, Dohmae, N, Aida, Y. 登録日 2014-01-17 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.629 Å) 主引用文献 Crystal structure of closed dimer of human importin-alpha1 (Rch1) To be Published
1UN0	Crystal Structure of Yeast Karyopherin (Importin) alpha in complex with a Nup2p N-terminal fragment 分子名称: IMPORTIN ALPHA SUBUNIT, NUCLEOPORIN NUP2 著者 Matsuura, Y, Lange, A, Harreman, M.T, Corbett, A.H, Stewart, M. 登録日 2003-09-03 公開日 2003-10-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis for Nup2P Function in Cargo Release and Karyopherin Recycling in Nuclear Import Embo J., 22, 2003
4PVZ	Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2 分子名称: Importin subunit alpha, Inner nuclear membrane protein HEH2 著者 Lokareddy, R.K, Hapsari, A.R, van Rheenen, M, Bhardwaj, A, Veenhoff, L.M, Cingolani, C. 登録日 2014-03-18 公開日 2015-08-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2. Structure, 23, 2015
8SG7	Adeno-Associated Virus Bat origin capsid protein basic regions in complex with importin-alpha 2 分子名称: Importin subunit alpha-1, VP1 capsid 著者 Hoad, M, Forwood, J.K. 登録日 2023-04-11 公開日 2023-07-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for nuclear import of bat adeno-associated virus capsid protein. J.Gen.Virol., 105, 2024
2JDQ	C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5 分子名称: IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC PROTEIN 2 著者 Tarendeau, F, Guilligay, D, Mas, P, Boulo, S, Baudin, F, Ruigrok, R.W.H, Hart, D.J, Cusack, S. 登録日 2007-01-11 公開日 2007-02-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and Nuclear Import Function of the C- Terminal Domain of Influenza Virus Polymerase Pb2 Subunit Nat.Struct.Mol.Biol., 14, 2007
7UMI	Importin a1 bound to Cp183-CTD 分子名称: HBV-NLS, Importin subunit alpha-1 著者 Yang, R, Cingolani, G. 登録日 2022-04-07 公開日 2023-10-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core. Sci Adv, 10, 2024
3TPO	Crystal structure of D192A/E396A mutant of mouse importin alpha2 分子名称: Importin subunit alpha-2 著者 Hirano, H, Matsuura, Y. 登録日 2011-09-08 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL Biochem.Biophys.Res.Commun., 414, 2011
3TPM	Crystal structure of MAL RPEL domain in complex with importin-alpha 分子名称: Importin subunit alpha-2, MAL 著者 Hirano, H, Matsuura, Y. 登録日 2011-09-08 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL Biochem.Biophys.Res.Commun., 414, 2011
4XZR	Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh1 分子名称: Importin subunit alpha, Inner nuclear membrane protein SRC1 著者 Lokareddy, R.K, Cingolani, G. 登録日 2015-02-04 公開日 2015-06-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2. Structure, 23, 2015
2QNA	Crystal structure of human Importin-beta (127-876) in complex with the IBB-domain of Snurportin1 (1-65) 分子名称: Importin subunit beta-1, SULFATE ION, Snurportin-1 著者 Wohlwend, D, Strasser, A, Dickmanns, A, Ficner, R. 登録日 2007-07-18 公開日 2008-04-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Structural basis for RanGTP independent entry of spliceosomal U snRNPs into the nucleus. J.Mol.Biol., 374, 2007
7JVO	Importin alpha bound to the C-terminus of ACE2 分子名称: ARG-LYS-LYS-LYS-ASN-LYS-ALA, Importin subunit alpha-1 著者 Forwood, J.K, Cross, E.M, Tsimbalyuk, S. 登録日 2020-08-22 公開日 2020-10-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication. Cell Discov, 7, 2021
5E6Q	Importin alpha binding to XRCC1 NLS peptide 分子名称: CHLORIDE ION, DNA repair protein XRCC1 NLS peptide, GLYCEROL, ... 著者 Pedersen, L.C, Kirby, T.W, Gassman, N.R, Smith, C.E, Gabel, S.A, Sobhany, M, Wilson, S.H, London, R.E. 登録日 2015-10-10 公開日 2015-10-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.305 Å) 主引用文献 Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS. Sci Rep, 5, 2015
5EKG	Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 2 分子名称: Importin subunit alpha-1, XPG2 peptide 著者 Barros, A.C, Takeda, A.A.S, Fontes, M.R.M. 登録日 2015-11-03 公開日 2016-02-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence. J.Mol.Biol., 428, 2016
7VPS	Crystal structure of the ARM domain of C. glabrata importin alpha 分子名称: Importin subunit alpha 著者 Tan, L, Im, Y.J. 登録日 2021-10-17 公開日 2022-09-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structural basis for activation of fungal sterol receptor Upc2 and azole resistance. Nat.Chem.Biol., 18, 2022
5FC8	Mouse importin alpha: Dengue 3 NS5 C-terminal NLS peptide complex 分子名称: Importin subunit alpha-1, Nonstructural protein 5 著者 Smith, K.M, Forwood, J.K. 登録日 2015-12-15 公開日 2016-05-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. PLoS Pathog., 12, 2016
5HHG	Mouse importin alpha: Dengue 2 NS5 C-terminal NLS peptide complex 分子名称: Importin subunit alpha-1, RNA-directed RNA polymerase NS5 著者 Smith, K.M, Forwood, J.K. 登録日 2016-01-11 公開日 2016-05-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. PLoS Pathog., 12, 2016
5W4E	Importin binding to Tdt NLS peptide 分子名称: GLYCEROL, Importin subunit alpha-1,Importin subunit alpha-1, human DNA repair polymerase Tdt 著者 Pedersen, L.C, London, R. 登録日 2017-06-10 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Variations in nuclear localization strategies among pol X family enzymes. Traffic, 2018
8FUA	Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein NLS1 分子名称: Importin subunit alpha-1, Matrix protein 著者 Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K. 登録日 2023-01-17 公開日 2023-02-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism. Viruses, 15, 2023
8FUB	Crystal structure of human Importin alpha 3 in complex with Hendra virus matrix protein NLS1 分子名称: Importin subunit alpha-3, Matrix protein 著者 Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K. 登録日 2023-01-17 公開日 2023-02-15 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism. Viruses, 15, 2023

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