4ZFA
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![BU of 4zfa by Molmil](/molmil-images/mine/4zfa) | Cytochrome P450 wild type from BM3 with bound PEG | 分子名称: | 1,2-ETHANEDIOL, Bifunctional P-450/NADPH-P450 reductase, NICKEL (II) ION, ... | 著者 | Rogers, W.E, Othman, T, Heidary, D.K, Huxford, T. | 登録日 | 2015-04-21 | 公開日 | 2016-07-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.765 Å) | 主引用文献 | Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry, 55, 2016
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4ZF6
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![BU of 4zf6 by Molmil](/molmil-images/mine/4zf6) | Cytochrome P450 pentamutant from BM3 with bound PEG | 分子名称: | 1,2-ETHANEDIOL, Bifunctional P-450/NADPH-P450 reductase, NICKEL (II) ION, ... | 著者 | Rogers, W.E, Othman, T, Heidary, D.K, Huxford, T. | 登録日 | 2015-04-21 | 公開日 | 2016-07-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.773 Å) | 主引用文献 | Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry, 55, 2016
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7TTP
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![BU of 7ttp by Molmil](/molmil-images/mine/7ttp) | P450 (OxyA) from kistamicin biosynthesis, mixed heme conformation | 分子名称: | GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 hydroxylase | 著者 | Greule, A, Izore, T, Cryle, M.J. | 登録日 | 2022-02-01 | 公開日 | 2022-05-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
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7TTA
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![BU of 7tta by Molmil](/molmil-images/mine/7tta) | P450 (OxyA) from kistamicin biosynthesis, mixed heme conformation, attenuated beam | 分子名称: | GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 hydroxylase | 著者 | Greule, A, Izore, T, Cryle, M.J. | 登録日 | 2022-02-01 | 公開日 | 2022-05-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
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7TTQ
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![BU of 7ttq by Molmil](/molmil-images/mine/7ttq) | P450 (OxyA) from kistamicin biosynthesis, imidazole complex | 分子名称: | GLYCEROL, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Greule, A, Izore, T, Cryle, M.J. | 登録日 | 2022-02-01 | 公開日 | 2022-05-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
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7TTO
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![BU of 7tto by Molmil](/molmil-images/mine/7tto) | |
7TTB
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![BU of 7ttb by Molmil](/molmil-images/mine/7ttb) | P450 (OxyA) from kistamicin biosynthesis, Y99F mutant | 分子名称: | GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 hydroxylase | 著者 | Greule, A, Izore, T, Cryle, M.J. | 登録日 | 2022-02-01 | 公開日 | 2022-05-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.801592 Å) | 主引用文献 | The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
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4ZF8
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![BU of 4zf8 by Molmil](/molmil-images/mine/4zf8) | Cytochrome P450 pentamutant from BM3 with bound Metyrapone | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, METYRAPONE, NICKEL (II) ION, ... | 著者 | Rogers, W.E, Othman, T, Heidary, D.K, Huxford, T. | 登録日 | 2015-04-21 | 公開日 | 2016-07-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.766 Å) | 主引用文献 | Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry, 55, 2016
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3T3R
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![BU of 3t3r by Molmil](/molmil-images/mine/3t3r) | Human Cytochrome P450 2A6 in complex with Pilocarpine | 分子名称: | (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE | 著者 | DeVore, N.M, Scott, E.E. | 登録日 | 2011-07-25 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine. Febs J., 279, 2012
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1RF9
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![BU of 1rf9 by Molmil](/molmil-images/mine/1rf9) | Crystal structure of cytochrome P450-cam with a fluorescent probe D-4-AD (Adamantane-1-carboxylic acid-5-dimethylamino-naphthalene-1-sulfonylamino-butyl-amide) | 分子名称: | 1,2-ETHANEDIOL, ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-BUTYL-AMIDE, Cytochrome P450-cam, ... | 著者 | Hays, A.-M.A, Dunn, A.R, Gray, H.B, Stout, C.D, Goodin, D.B. | 登録日 | 2003-11-07 | 公開日 | 2004-11-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Conformational States of Cytochrome P450cam Revealed by Trapping of synthetic Molecular Wires J.Mol.Biol., 344, 2004
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3T3Q
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![BU of 3t3q by Molmil](/molmil-images/mine/3t3q) | Human Cytochrome P450 2A6 I208S/I300F/G301A/S369G in complex with Pilocarpine | 分子名称: | (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE | 著者 | DeVore, N.M, Scott, E.E. | 登録日 | 2011-07-25 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine. Febs J., 279, 2012
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3MVR
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![BU of 3mvr by Molmil](/molmil-images/mine/3mvr) | |
2J0D
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![BU of 2j0d by Molmil](/molmil-images/mine/2j0d) | |
3LC4
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![BU of 3lc4 by Molmil](/molmil-images/mine/3lc4) | |
4GQS
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![BU of 4gqs by Molmil](/molmil-images/mine/4gqs) | Structure of Human Microsomal Cytochrome P450 (CYP) 2C19 | 分子名称: | (4-hydroxy-3,5-dimethylphenyl)(2-methyl-1-benzofuran-3-yl)methanone, Cytochrome P450 2C19, GLYCEROL, ... | 著者 | Reynald, R.L, Sansen, S, Stout, C.D, Johnson, E.F. | 登録日 | 2012-08-23 | 公開日 | 2012-11-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | Structural Characterization of Human Cytochrome P450 2C19: ACTIVE SITE DIFFERENCES BETWEEN P450s 2C8, 2C9, AND 2C19. J.Biol.Chem., 287, 2012
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5T6Q
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5OGX
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![BU of 5ogx by Molmil](/molmil-images/mine/5ogx) | Crystal structure of Amycolatopsis cytochrome P450 reductase GcoB. | 分子名称: | BROMIDE ION, Cytochrome P450 reductase, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Mallinson, S.J.B, Johnson, C.W, Neidle, E.L, Beckham, G.T, McGeehan, J.E. | 登録日 | 2017-07-13 | 公開日 | 2018-07-04 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion. Nat Commun, 9, 2018
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1RE9
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![BU of 1re9 by Molmil](/molmil-images/mine/1re9) | CRYSTAL STRUCTURE OF CYTOCHROME P450-CAM WITH A FLUORESCENT PROBE D-8-AD (ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-OCTYL-AMIDE) | 分子名称: | 1,2-ETHANEDIOL, ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-OCTYL-AMIDE, Cytochrome P450-cam, ... | 著者 | Hays, A.-M.A, Dunn, A.R, Gray, H.B, Stout, C.D, Goodin, D.B. | 登録日 | 2003-11-06 | 公開日 | 2004-11-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Conformational states of cytochrome P450cam revealed by trapping of synthetic molecular wires. J.Mol.Biol., 344, 2004
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1YRD
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![BU of 1yrd by Molmil](/molmil-images/mine/1yrd) | X-ray crystal structure of PERDEUTERATED Cytochrome P450cam | 分子名称: | CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... | 著者 | Meilleur, F, Dauvergne, M.-T, Schlichting, I, Myles, D.A.A. | 登録日 | 2005-02-03 | 公開日 | 2005-02-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Production and X-ray crystallographic analysis of fully deuterated cytochrome P450cam. Acta Crystallogr.,Sect.D, 61, 2005
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2D09
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![BU of 2d09 by Molmil](/molmil-images/mine/2d09) | |
2GQX
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![BU of 2gqx by Molmil](/molmil-images/mine/2gqx) | Crystal structure of cytochrome p450cam mutant (f87w/y96f/l244a/v247l/c334a) with pentachlorobenzene | 分子名称: | 1,2,3,4,5-PENTACHLOROBENZENE, Cytochrome P450-cam, POTASSIUM ION, ... | 著者 | Rao, Z, Wong, L.L, Xu, F, Bell, S.G. | 登録日 | 2006-04-22 | 公開日 | 2007-04-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-activity correlations in pentachlorobenzene oxidation by engineered cytochrome P450cam Protein Eng.Des.Sel., 20, 2007
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3T3S
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![BU of 3t3s by Molmil](/molmil-images/mine/3t3s) | Human Cytochrome P450 2A13 in complex with Pilocarpine | 分子名称: | (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, Cytochrome P450 2A13, PROTOPORPHYRIN IX CONTAINING FE | 著者 | DeVore, N.M, Scott, E.E. | 登録日 | 2011-07-25 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine. Febs J., 279, 2012
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6DWM
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![BU of 6dwm by Molmil](/molmil-images/mine/6dwm) | Structure of Human Cytochrome P450 1A1 with Bergamottin | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, 4-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-7H-furo[3,2-g][1]benzopyran-7-one, Cytochrome P450 1A1, ... | 著者 | Bart, A.G, Scott, E.E. | 登録日 | 2018-06-26 | 公開日 | 2018-10-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structures of human cytochrome P450 1A1 with bergamottin and erlotinib reveal active-site modifications for binding of diverse ligands. J. Biol. Chem., 293, 2018
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6DWN
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![BU of 6dwn by Molmil](/molmil-images/mine/6dwn) | Structure of Human Cytochrome P450 1A1 with Erlotinib | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Cytochrome P450 1A1, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Bart, A.G, Scott, E.E. | 登録日 | 2018-06-26 | 公開日 | 2018-10-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structures of human cytochrome P450 1A1 with bergamottin and erlotinib reveal active-site modifications for binding of diverse ligands. J. Biol. Chem., 293, 2018
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2D0E
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![BU of 2d0e by Molmil](/molmil-images/mine/2d0e) | Substrate assited in Oxygen Activation in Cytochrome P450 158A2 | 分子名称: | 2-HYDROXYNAPHTHOQUINONE, PROTOPORPHYRIN IX CONTAINING FE, putative cytochrome P450 | 著者 | Zhao, B, Waterman, M.R. | 登録日 | 2005-08-02 | 公開日 | 2005-10-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Role of active site water molecules and substrate hydroxyl groups in oxygen activation by cytochrome P450 158A2: a new mechanism of proton transfer J.Biol.Chem., 280, 2005
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