3AJ3
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![BU of 3aj3 by Molmil](/molmil-images/mine/3aj3) | Crystal structure of selenomethionine substituted 4-pyridoxolactonase from Mesorhizobium loti | 分子名称: | 4-pyridoxolactonase, PHOSPHATE ION, ZINC ION | 著者 | Kobayashi, J, Yoshikane, Y, Baba, S, Mikami, B, Yagi, T. | 登録日 | 2010-05-21 | 公開日 | 2011-05-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.577 Å) | 主引用文献 | Structure of 4-pyridoxolactonase from Mesorhizobium loti. Acta Crystallogr.,Sect.F, 70, 2014
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4NQ6
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![BU of 4nq6 by Molmil](/molmil-images/mine/4nq6) | Bacillus cereus Zn-dependent metallo-beta-lactamase at pH 7 complexed with compound L-CS319 | 分子名称: | (3S,5S,7aR)-5-(sulfanylmethyl)tetrahydro[1,3]thiazolo[4,3-b][1,3]thiazole-3-carboxylic acid, Beta-lactamase 2, POTASSIUM ION, ... | 著者 | Gonzalez, J.M, Gonzalez, M.M, Vila, A.J. | 登録日 | 2013-11-23 | 公開日 | 2014-11-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Cross-class metallo-beta-lactamase inhibition by bisthiazolidines reveals multiple binding modes. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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4O98
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![BU of 4o98 by Molmil](/molmil-images/mine/4o98) | Crystal structure of Pseudomonas oleovorans PoOPH mutant H250I/I263W | 分子名称: | ZINC ION, organophosphorus hydrolase | 著者 | Luo, X.J, Kong, X.D, Zhao, J, Chen, Q, Zhou, J.H, Xu, J.H. | 登録日 | 2014-01-02 | 公開日 | 2014-12-03 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | 主引用文献 | Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp Biotechnol.Bioeng., 111, 2014
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7WZU
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![BU of 7wzu by Molmil](/molmil-images/mine/7wzu) | Crystal structure of metallo-beta-lactamase IMP-6. | 分子名称: | Beta-lactamase, ZINC ION | 著者 | Yamaguchi, Y, Kurosaki, H. | 登録日 | 2022-02-19 | 公開日 | 2023-01-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.954 Å) | 主引用文献 | Difference in the Inhibitory Effect of Thiol Compounds and Demetallation Rates from the Zn(II) Active Site of Metallo-beta-lactamases (IMP-1 and IMP-6) Associated with a Single Amino Acid Substitution. Acs Infect Dis., 9, 2023
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7XHX
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![BU of 7xhx by Molmil](/molmil-images/mine/7xhx) | Crystal structure of metallo-beta-lactamase IMP-6 | 分子名称: | Beta-lactamase, ZINC ION | 著者 | Yamamoto, K, Tanaka, H, Kurisu, G, Nakano, R, Yano, H, Sakai, H. | 登録日 | 2022-04-11 | 公開日 | 2023-02-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural insights into the substrate specificity of IMP-6 and IMP-1 metallo-beta-lactamases. J.Biochem., 173, 2022
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7XHW
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![BU of 7xhw by Molmil](/molmil-images/mine/7xhw) | Crystal structure of metallo-beta-lactamase IMP-1 | 分子名称: | Beta-lactamase, ZINC ION | 著者 | Yamamoto, K, Tanaka, H, Kurisu, G, Nakano, R, Yano, H, Sakai, H. | 登録日 | 2022-04-11 | 公開日 | 2023-02-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structural insights into the substrate specificity of IMP-6 and IMP-1 metallo-beta-lactamases. J.Biochem., 173, 2022
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4P62
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![BU of 4p62 by Molmil](/molmil-images/mine/4p62) | |
7Y7U
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![BU of 7y7u by Molmil](/molmil-images/mine/7y7u) | |
7YHB
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![BU of 7yhb by Molmil](/molmil-images/mine/7yhb) | Crystal structure of VIM-2 MBL in complex with (2-(4-phenyl-1H-1,2,3-triazol-1-yl)benzyl)phosphonic acid | 分子名称: | Beta-lactamase class B VIM-2, ZINC ION, [2-(4-phenyl-1,2,3-triazol-1-yl)phenyl]methylphosphonic acid | 著者 | Li, G.-B, Yan, Y.-H. | 登録日 | 2022-07-13 | 公開日 | 2023-06-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Metal binding pharmacophore click-derived discovery of new broad-spectrum metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 257, 2023
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7YH9
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![BU of 7yh9 by Molmil](/molmil-images/mine/7yh9) | Crystal structure of IMP-1 MBL in complex with 3-(4-benzyl-1H-1,2,3-triazol-1-yl)phthalic acid | 分子名称: | 3-[4-(phenylmethyl)-1,2,3-triazol-1-yl]phthalic acid, Beta-lactamase class B IMP-1, ZINC ION | 著者 | Li, G.-B, Yan, Y.-H. | 登録日 | 2022-07-13 | 公開日 | 2023-06-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Metal binding pharmacophore click-derived discovery of new broad-spectrum metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 257, 2023
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7YHD
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![BU of 7yhd by Molmil](/molmil-images/mine/7yhd) | Crystal structure of VIM-2 MBL in complex with 3-(4-(4-(2-aminoethoxy)phenyl)-1H-1,2,3-triazol-1-yl)phthalic acid | 分子名称: | 3-[4-[4-(2-azanylethoxy)phenyl]-1,2,3-triazol-1-yl]phthalic acid, Beta-lactamase class B VIM-2, ZINC ION | 著者 | Li, G.-B, Yan, Y.-H. | 登録日 | 2022-07-13 | 公開日 | 2023-06-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | 主引用文献 | Metal binding pharmacophore click-derived discovery of new broad-spectrum metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 257, 2023
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7YHC
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![BU of 7yhc by Molmil](/molmil-images/mine/7yhc) | Crystal structure of VIM-2 MBL in complex with 3-(4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl)phthalic acid | 分子名称: | 3-[4-(3-aminophenyl)-1,2,3-triazol-1-yl]phthalic acid, Beta-lactamase class B VIM-2, ZINC ION | 著者 | Li, G.-B, Yan, Y.-H. | 登録日 | 2022-07-13 | 公開日 | 2023-06-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.153 Å) | 主引用文献 | Metal binding pharmacophore click-derived discovery of new broad-spectrum metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 257, 2023
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7YHA
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![BU of 7yha by Molmil](/molmil-images/mine/7yha) | Crystal structure of IMP-1 MBL in complex with (3-(4-(p-tolyl)-1H-1,2,3-triazol-1-yl)benzyl)phosphonic acid | 分子名称: | Beta-lactamase class B IMP-1, ZINC ION, [3-[4-(4-methylphenyl)-1,2,3-triazol-1-yl]phenyl]methylphosphonic acid | 著者 | Li, G.-B, Yan, Y.-H. | 登録日 | 2022-07-13 | 公開日 | 2023-06-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.135 Å) | 主引用文献 | Metal binding pharmacophore click-derived discovery of new broad-spectrum metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 257, 2023
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4NQ5
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![BU of 4nq5 by Molmil](/molmil-images/mine/4nq5) | Bacillus cereus Zn-dependent metallo-beta-lactamase at pH 7 complexed with compound CS319 | 分子名称: | (3R,5R,7aS)-5-(sulfanylmethyl)tetrahydro[1,3]thiazolo[4,3-b][1,3]thiazole-3-carboxylic acid, Beta-lactamase 2, POTASSIUM ION, ... | 著者 | Gonzalez, J.M, Gonzalez, M.M, Vila, A.J. | 登録日 | 2013-11-23 | 公開日 | 2014-11-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Inhibition of metallo-lactamases with bicyclic compounds TO BE PUBLISHED
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4NQ2
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![BU of 4nq2 by Molmil](/molmil-images/mine/4nq2) | Structure of Zn(II)-bound metallo-beta-lactamse VIM-2 from Pseudomonas aeruginosa | 分子名称: | ACETATE ION, Beta-lactamase class B VIM-2, ZINC ION | 著者 | Aitha, M, Nix, J.C, Crowder, M.W, Page, R.C. | 登録日 | 2013-11-23 | 公開日 | 2014-11-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Biochemical, Mechanistic, and Spectroscopic Characterization of Metallo-beta-lactamase VIM-2. Biochemistry, 53, 2014
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7YRP
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![BU of 7yrp by Molmil](/molmil-images/mine/7yrp) | |
4PVT
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![BU of 4pvt by Molmil](/molmil-images/mine/4pvt) | Crystal Structure of VIM-2 metallo-beta-lactamase in complex with ML302F | 分子名称: | (2Z)-2-sulfanyl-3-(2,3,6-trichlorophenyl)prop-2-enoic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ... | 著者 | Aik, W.S, Brem, J, McDonough, M.A, Schofield, C.J. | 登録日 | 2014-03-18 | 公開日 | 2014-11-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Rhodanine hydrolysis leads to potent thioenolate mediated metallo-beta-lactamase inhibition. Nat.Chem., 6, 2014
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4NQ4
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![BU of 4nq4 by Molmil](/molmil-images/mine/4nq4) | |
4PVO
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![BU of 4pvo by Molmil](/molmil-images/mine/4pvo) | Crystal Structure of VIM-2 metallo-beta-lactamase in complex with ML302 and ML302F | 分子名称: | (2Z)-2-sulfanyl-3-(2,3,6-trichlorophenyl)prop-2-enoic acid, Beta-lactamase class B VIM-2, DIMETHYL SULFOXIDE, ... | 著者 | Aik, W.S, Brem, J, McDonough, M.A, Schofield, C.J. | 登録日 | 2014-03-18 | 公開日 | 2014-11-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Rhodanine hydrolysis leads to potent thioenolate mediated metallo-beta-lactamase inhibition. Nat.Chem., 6, 2014
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3T9M
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![BU of 3t9m by Molmil](/molmil-images/mine/3t9m) | |
2P4Z
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![BU of 2p4z by Molmil](/molmil-images/mine/2p4z) | |
2QDS
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![BU of 2qds by Molmil](/molmil-images/mine/2qds) | |
3SRX
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![BU of 3srx by Molmil](/molmil-images/mine/3srx) | New Delhi Metallo-beta-Lactamase-1 Complexed with Cd | 分子名称: | Beta-lactamase NDM-1, CADMIUM ION, CHLORIDE ION, ... | 著者 | Kim, Y, Tesar, C, Jedrzejczak, R, Babnigg, J, Binkowski, T.A, Mire, J, Sacchettini, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | 登録日 | 2011-07-07 | 公開日 | 2011-07-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | New Delhi Metallo-beta-Lactamase-1 Complexed with Cd To be Published
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3SD9
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![BU of 3sd9 by Molmil](/molmil-images/mine/3sd9) | |
3SPU
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![BU of 3spu by Molmil](/molmil-images/mine/3spu) | apo NDM-1 Crystal Structure | 分子名称: | Beta-lactamase NDM-1, ZINC ION | 著者 | Strynadka, N.C.J, King, D.T. | 登録日 | 2011-07-03 | 公開日 | 2011-08-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of New Delhi metallo-beta-lactamase reveals molecular basis for antibiotic resistance Protein Sci., 20, 2011
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