7YH9
Crystal structure of IMP-1 MBL in complex with 3-(4-benzyl-1H-1,2,3-triazol-1-yl)phthalic acid
Summary for 7YH9
Entry DOI | 10.2210/pdb7yh9/pdb |
Descriptor | Beta-lactamase class B IMP-1, ZINC ION, 3-[4-(phenylmethyl)-1,2,3-triazol-1-yl]phthalic acid, ... (4 entities in total) |
Functional Keywords | metallo-beta-lactamase class imp-1, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 6 |
Total formula weight | 147958.54 |
Authors | Li, G.-B.,Yan, Y.-H. (deposition date: 2022-07-13, release date: 2023-06-07, Last modification date: 2023-11-29) |
Primary citation | Yan, Y.H.,Ding, H.S.,Zhu, K.R.,Mu, B.S.,Zheng, Y.,Huang, M.Y.,Zhou, C.,Li, W.F.,Wang, Z.,Wu, Y.,Li, G.B. Metal binding pharmacophore click-derived discovery of new broad-spectrum metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 257:115473-115473, 2023 Cited by PubMed: 37209449DOI: 10.1016/j.ejmech.2023.115473 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.39 Å) |
Structure validation
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