PDB: 394 件ウェブページステータス検索Chemie searchBIRD

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3F92	Crystal structure of ubiquitin-conjugating enzyme E2-25kDa (Huntington Interacting Protein 2) M172A mutant crystallized at pH 8.5 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CALCIUM ION, ... 著者 Wilson, R.C, Hughes, R.C, Flatt, J.W, Meehan, E.J, Ng, J.D, Twigg, P.D. 登録日 2008-11-13 公開日 2008-11-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2). Acta Crystallogr.,Sect.F, 65, 2009
8A58	X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W 分子名称: E3 ubiquitin-protein ligase TRIM21, Ubiquitin-conjugating enzyme E2 W, ZINC ION 著者 James, L.C, Kiss, L. 登録日 2022-06-14 公開日 2023-04-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates. Nat Commun, 14, 2023
5VZW	TRIM23 RING domain in complex with UbcH5-Ub 分子名称: E3 ubiquitin-protein ligase TRIM23, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ... 著者 Pornillos, O, Dawidziak, D. 登録日 2017-05-29 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.278 Å) 主引用文献 Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase. Proteins, 85, 2017
4R62	Structure of Rad6~Ub 分子名称: ACETATE ION, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 2 著者 Kumar, P, Wolberger, C. 登録日 2014-08-22 公開日 2015-09-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity. Nucleic Acids Res., 43, 2015
3UIP	Complex between human RanGAP1-SUMO1, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II 分子名称: E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... 著者 Gareau, J.R, Reverter, D, Lima, C.D. 登録日 2011-11-05 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.293 Å) 主引用文献 Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2. J.Biol.Chem., 287, 2012
6ZHT	Uba1-Ubc13 disulfide mediated complex 分子名称: CHLORIDE ION, GLYCEROL, Ubiquitin-activating enzyme E1 1, ... 著者 Schaefer, A, Misra, M, Schindelin, H. 登録日 2020-06-23 公開日 2022-01-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system. To Be Published
4NRI	Crystal Structure of a human Mms2/Ubc13 A122G mutant 分子名称: GLYCEROL, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 著者 Hodge, C.D, Edwards, R.A, Glover, J.N.M. 登録日 2013-11-26 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes. J.Am.Chem.Soc., 136, 2014
4LAD	Crystal Structure of the Ube2g2:RING-G2BR complex 分子名称: E3 ubiquitin-protein ligase AMFR, OXALATE ION, Ubiquitin-conjugating enzyme E2 G2, ... 著者 Liang, Y.-H, Li, J, Das, R, Byrd, R.A, Ji, X. 登録日 2013-06-19 公開日 2013-08-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine. Embo J., 32, 2013
2BF8	Crystal structure of SUMO modified ubiquitin conjugating enzyme E2- 25K 分子名称: UBIQUITIN-CONJUGATING ENZYME E2-25 KDA, UBIQUITIN-LIKE PROTEIN SMT3C 著者 Pichler, A, Knipscheer, P, Oberhofer, E, Van Dijk, W.J, Korner, R, Velgaard Olsen, J, Jentsch, S, Melchior, F, Sixma, T.K. 登録日 2004-12-06 公開日 2005-02-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Sumo Imodification of the Ubiquitin Conjugating Enzyme E2-25K Nat.Struct.Mol.Biol., 12, 2005
8E2H	Cryo-EM structure of C-terminal arm of BIRC6 (from local refinement 4) 分子名称: Baculoviral IAP repeat-containing protein 6 著者 Hunkeler, M, Fischer, E.S. 登録日 2022-08-15 公開日 2023-02-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases. Science, 379, 2023
8UQ9	Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 4-residue linker 分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, GLYCEROL, ... 著者 Hu, Q, Botuyan, M.V, Mer, G. 登録日 2023-10-23 公開日 2024-01-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
6W9A	RNF12 RING domain in complex with Ube2e2 分子名称: E3 ubiquitin-protein ligase RLIM, GLYCEROL, Ubiquitin-conjugating enzyme E2 E2, ... 著者 Middleton, A.J, Day, C.L. 登録日 2020-03-22 公開日 2020-05-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains. J.Mol.Biol., 432, 2020
3RZ3	Human Cdc34 E2 in complex with CC0651 inhibitor 分子名称: 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid, Ubiquitin-conjugating enzyme E2 R1 著者 Ceccarelli, D.F, Webb, D.R, Sicheri, F. 登録日 2011-05-11 公開日 2011-07-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 An allosteric inhibitor of the human cdc34 ubiquitin conjugating enzyme Cell(Cambridge,Mass.), 145, 2011
4IP3	Complex structure of OspI and Ubc13 分子名称: ORF169b, Ubiquitin-conjugating enzyme E2 N 著者 Fu, P, Jin, M, Zhang, X, Xu, L, Xia, Z, Zhu, Y. 登録日 2013-01-09 公開日 2013-03-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure Analysis of Ubc13 Inactivation To be Published
3ONG	Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways 分子名称: SUMO-conjugating enzyme UBC9, Ubiquitin-activating enzyme E1-like 著者 Wang, J, Taherbhoy, A.M, Hunt, H.W, Seyedin, S.N, Miller, D.W, Huang, D.T, Schulman, B.A. 登録日 2010-08-28 公開日 2011-01-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways. Plos One, 5, 2010
8UQ8	Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 2-residue linker 分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, GLYCEROL, ... 著者 Hu, Q, Botuyan, M.V, Mer, G. 登録日 2023-10-23 公開日 2024-01-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
5FER	Complex of TRIM25 RING with UbcH5-Ub 分子名称: E3 ubiquitin/ISG15 ligase TRIM25, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D1, ... 著者 Rittinger, K, Koliopoulos, M.G, Esposito, D. 登録日 2015-12-17 公開日 2016-05-18 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity. Embo J., 35, 2016
6UMS	Crystal structure of MavC in complex with its substrate mimic in C222(1) space group 分子名称: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N 著者 Iyer, S, Puvar, K, Das, C. 登録日 2019-10-10 公開日 2020-05-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.344 Å) 主引用文献 Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
3UGB	UbcH5c~Ubiquitin Conjugate 分子名称: GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3 著者 Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S. 登録日 2011-11-02 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates. Biochemistry, 51, 2012
6ZHS	Uba1 bound to two E2 (Ubc13) molecules 分子名称: GLYCEROL, SULFATE ION, Ubiquitin-activating enzyme E1 1, ... 著者 Misra, M, Schindelin, H. 登録日 2020-06-23 公開日 2022-01-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system. To Be Published
2C4P	Crystal structure of human ubiquitin-conjugating enzyme UbcH5A 分子名称: UBIQUITIN-CONJUGATING ENZYME E2 D1 著者 Dodd, R.B, Read, R.J. 登録日 2005-10-21 公開日 2006-11-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structures of Two Human Ubiquitin-Conjugating Enzymes from Twinned Crystals To be Published
4DHJ	The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex 分子名称: Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... 著者 Wiener, R, Zhang, X, Wang, T, Wolberger, C. 登録日 2012-01-27 公開日 2012-02-22 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature, 483, 2012
6D68	Ube2G1 in complex with ubiquitin variant Ubv.G1.1 分子名称: Ubiquitin-conjugating enzyme E2 G1, Ubv.G1.1 著者 Ceccarelli, D.F, Garg, P, Sidhu, S, Sicheri, F. 登録日 2018-04-20 公開日 2019-07-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes. J.Mol.Biol., 432, 2020
5ULK	Crystal Structure of RNF165 in complex with a UbcH5b~Ub conjugate 分子名称: E3 ubiquitin-protein ligase RNF165, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ... 著者 Middleton, A.J, Day, C.L, Wright, J.D. 登録日 2017-01-24 公開日 2017-06-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Discovery of new non-covalent ubiquitin binding sites on UbcH5 To be published
2ONU	Plasmodium falciparum ubiquitin conjugating enzyme PF10_0330, putative homologue of human UBE2H 分子名称: TETRAETHYLENE GLYCOL, Ubiquitin-conjugating enzyme, putative 著者 Dong, A, Lew, J, Lin, L, Hassanali, A, Zhao, Y, Senisterra, G, Wasney, G, Vedadi, M, Kozieradzki, I, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Hui, R, Brokx, S.J, Structural Genomics Consortium (SGC) 登録日 2007-01-24 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Plasmodium falciparum ubiquitin conjugating enzyme PF10_0330, putative homologue of human UBE2H To be Published

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