PDB: 338 件ウェブページステータス検索Chemie searchBIRD

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4U85	Human Pin1 with cysteine sulfinic acid 113 分子名称: POLYETHYLENE GLYCOL (N=34), Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Li, W, Zhang, Y. 登録日 2014-08-01 公開日 2015-04-08 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol.Dis., 76, 2015
4X7I	Crystal Structure of BACE with amino thiazine inhibitor LY2886721 分子名称: Beta-secretase 1, GLYCEROL, N-{3-[(4aS,7aS)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide 著者 Timm, D.E. 登録日 2014-12-09 公開日 2014-12-24 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central A beta Pharmacodynamic Responses in Mice, Dogs, and Humans. J.Neurosci., 35, 2015
4XPW	Crystal structures of Leu114F mutant 分子名称: Bacteriohemerythrin, FE (II) ION, GLYCEROL 著者 Chuankhayan, P, Chen, K.H.C, Wu, H.H, Chen, C.J, Fukuda, M, Yu, S.S.F, Chan, S.I. 登録日 2015-01-18 公開日 2015-04-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 The bacteriohemerythrin from Methylococcus capsulatus (Bath): Crystal structures reveal that Leu114 regulates a water tunnel. J.Inorg.Biochem., 150, 2015
4XPY	Crystal structure of hemerythrin : L114Y mutant 分子名称: Bacteriohemerythrin, FE (II) ION, GLYCEROL 著者 Chuankhayan, P, Chen, K.H.C, Wu, H.H, Chen, C.J, Fukuda, M, Yu, S.S.F, Chan, S.I. 登録日 2015-01-18 公開日 2015-04-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 The bacteriohemerythrin from Methylococcus capsulatus (Bath): Crystal structures reveal that Leu114 regulates a water tunnel. J.Inorg.Biochem., 150, 2015
5VT2	Crystal structure of growth differentiation factor 分子名称: 1,2-ETHANEDIOL, Growth/differentiation factor 15 著者 Min, X, Wang, Z. 登録日 2017-05-15 公開日 2017-11-01 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys. Sci Transl Med, 9, 2017
3TPM	Crystal structure of MAL RPEL domain in complex with importin-alpha 分子名称: Importin subunit alpha-2, MAL 著者 Hirano, H, Matsuura, Y. 登録日 2011-09-08 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL Biochem.Biophys.Res.Commun., 414, 2011
3TPQ	Crystal structure of wild-type MAL RPEL domain in complex with five G-actins 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Hirano, H, Matsuura, Y. 登録日 2011-09-08 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL Biochem.Biophys.Res.Commun., 414, 2011
3TPO	Crystal structure of D192A/E396A mutant of mouse importin alpha2 分子名称: Importin subunit alpha-2 著者 Hirano, H, Matsuura, Y. 登録日 2011-09-08 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL Biochem.Biophys.Res.Commun., 414, 2011
3VJI	Human PPAR gamma ligand binding domain in complex with JKPL53 分子名称: (2S)-2-{4-butoxy-3-[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]benzoyl}amino)methyl]benzyl}butanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Tomioka, D, Kuwabara, N, Hashimoto, H, Sato, M, Shimizu, T. 登録日 2011-10-20 公開日 2012-08-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Peroxisome proliferator-activated receptors (PPARs) have multiple binding points that accommodate ligands in various conformations: phenylpropanoic acid-type PPAR ligands bind to PPAR in different conformations, depending on the subtype. J.Med.Chem., 55, 2012
8EMQ	Mouse apoferritin heavy chain with zinc determined using single-particle cryo-EM with Apollo camera. 分子名称: FE (III) ION, Ferritin heavy chain, N-terminally processed, ... 著者 Peng, R, Fu, X, Mendez, J.H, Randolph, P.H, Bammes, B, Stagg, S.M. 登録日 2022-09-28 公開日 2022-12-21 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (1.66 Å) 主引用文献 Characterizing the resolution and throughput of the Apollo direct electron detector. J Struct Biol X, 7, 2023
8EN7	Mouse apoferritin heavy chain without zinc determined using single-particle cryo-EM with Apollo camera. 分子名称: FE (III) ION, Ferritin heavy chain, N-terminally processed 著者 Peng, R, Fu, X, Mendez, J.H, Randolph, P.H, Bammes, B, Stagg, S.M. 登録日 2022-09-28 公開日 2022-12-21 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (1.68 Å) 主引用文献 Characterizing the resolution and throughput of the Apollo direct electron detector. J Struct Biol X, 7, 2023
6OLU	RIAM RA-PH core structure in the P212121 space group 分子名称: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein 著者 Wu, J. 登録日 2019-04-17 公開日 2020-04-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Phosphorylation of RIAM by src promotes integrin activation by unmasking the PH domain of RIAM. Structure, 29, 2021
6O6H	RIAM cc-RA-PH structure in the P21212 space group 分子名称: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein 著者 Wu, J. 登録日 2019-03-06 公開日 2020-09-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Phosphorylation of RIAM by Src Promotes Integrin Activation by Unmasking the PH Domain of RIAM. Structure, 2020
3VJH	Human PPAR GAMMA ligand binding domain in complex with JKPL35 分子名称: (2S)-2-[4-methoxy-3-({[4-(trifluoromethyl)benzoyl]amino}methyl)benzyl]pentanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Tomioka, D, Kuwabara, N, Hashimoto, H, Sato, M, Shimizu, T. 登録日 2011-10-20 公開日 2012-08-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Peroxisome proliferator-activated receptors (PPARs) have multiple binding points that accommodate ligands in various conformations: phenylpropanoic acid-type PPAR ligands bind to PPAR in different conformations, depending on the subtype. J.Med.Chem., 55, 2012
3VU3	Crystal structure of the Hfq and catalase HPII complex 分子名称: Catalase HPII, PROTOPORPHYRIN IX CONTAINING FE, Protein hfq 著者 Watanabe, M, Yonekura, K. 登録日 2012-06-15 公開日 2013-11-20 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Post-Transcriptional Regulator Hfq Binds Catalase HPII: Crystal Structure of the Complex Plos One, 8, 2013
3UES	Crystal structure of alpha-1,3/4-fucosidase from Bifidobacterium longum subsp. infantis complexed with deoxyfuconojirimycin 分子名称: (2S,3R,4S,5R)-2-METHYLPIPERIDINE-3,4,5-TRIOL, 1,2-ETHANEDIOL, Alpha-1,3/4-fucosidase, ... 著者 Sakurama, H, Fushinobu, S, Yoshida, E, Honda, Y, Hidaka, M, Ashida, H, Kitaoka, M, Katayama, T, Yamamoto, K, Kumagai, H. 登録日 2011-10-31 公開日 2012-04-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 1,3-1,4-alpha-L-fucosynthase that specifically introduces Lewis a/x antigens into type-1/2 chains J.Biol.Chem., 287, 2012
3UET	Crystal structure of alpha-1,3/4-fucosidase from Bifidobacterium longum subsp. infantis D172A/E217A mutant complexed with lacto-N-fucopentaose II 分子名称: 1,2-ETHANEDIOL, Alpha-1,3/4-fucosidase, SODIUM ION, ... 著者 Sakurama, H, Fushinobu, S, Yoshida, E, Honda, Y, Hidaka, M, Ashida, H, Kitaoka, M, Katayama, T, Yamamoto, K, Kumagai, H. 登録日 2011-10-31 公開日 2012-04-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 1,3-1,4-alpha-L-fucosynthase that specifically introduces Lewis a/x antigens into type-1/2 chains J.Biol.Chem., 287, 2012
3WWV	C-terminal domain of stomatin operon partner protein 1510-C from Pyrococcus horikoshii 分子名称: SODIUM ION, Stomatin operon partner protein 著者 Yokoyama, H, Matsui, I. 登録日 2014-06-30 公開日 2014-10-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the stomatin operon partner protein from Pyrococcus horikoshii indicates the formation of a multimeric assembly FEBS Open Bio, 4, 2014
6EXQ	Crystal Structure of Rhodesain in complex with a Macrolactam Inhibitor 分子名称: (3~{S})-19-chloranyl-~{N}-(1-cyanocyclopropyl)-8-methoxy-5-oxidanylidene-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(20),6(11),7,9,18,21-hexaene-3-carboxamide, 1,2-ETHANEDIOL, Cysteine protease 著者 Dietzel, U, Kisker, C. 登録日 2017-11-08 公開日 2018-04-11 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors. J. Med. Chem., 61, 2018
6H5H	A computationally designed dRP lyase domain reconstructed from two heterologous fragments 分子名称: polb4 著者 ElGamacy, M, Coles, M, Lupas, A.N. 登録日 2018-07-24 公開日 2018-12-12 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Asymmetric protein design from conserved supersecondary structures. J. Struct. Biol., 204, 2018
6HIL	X-ray structure of TEAD1(Y421H mutant) complexed with YAP(wildtype): Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy 分子名称: MYRISTIC ACID, Transcriptional coactivator YAP1, Transcriptional enhancer factor TEF-1 著者 Kallen, J. 登録日 2018-08-30 公開日 2019-04-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy. Febs J., 286, 2019
4Q2A	WNK1: A chloride sensor via autophosphorylation 分子名称: BROMIDE ION, Serine/threonine-protein kinase WNK1 著者 Piala, A, Moon, T, Akella, R, He, H, Cobb, M.H, Goldsmith, E. 登録日 2014-04-07 公開日 2014-05-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Chloride Sensing by WNK1 Involves Inhibition of Autophosphorylation. Sci.Signal., 7, 2014
4S2X	Structure of E. coli RppH bound to RNA and two magnesium ions 分子名称: MAGNESIUM ION, RNA (5'-R(*(APC)*GP*U)-3'), RNA pyrophosphohydrolase, ... 著者 Vasilyev, N, Serganov, A. 登録日 2015-01-23 公開日 2015-02-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structures of RNA Complexes with the Escherichia coli RNA Pyrophosphohydrolase RppH Unveil the Basis for Specific 5'-End-dependent mRNA Decay. J.Biol.Chem., 290, 2015
4P7T	Structural insights into higher-order assembly and function of the bacterial microcompartment protein PduA 分子名称: Polyhedral bodies 著者 Pickersgill, R.W, Frank, S, Pang, A, Warren, M.J. 登録日 2014-03-27 公開日 2014-06-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Structural Insights into Higher Order Assembly and Function of the Bacterial Microcompartment Protein PduA. J.Biol.Chem., 289, 2014
4P7V	Structural insights into higher-order assembly and function of the bacterial microcompartment protein PduA 分子名称: GLYCEROL, Polyhedral bodies 著者 Pang, A, Frank, S, Brown, I.R, Warren, M.J, Pickersgill, R.W. 登録日 2014-03-27 公開日 2014-06-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structural Insights into Higher Order Assembly and Function of the Bacterial Microcompartment Protein PduA. J.Biol.Chem., 289, 2014

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