PDB: 326 件ウェブページステータス検索Chemie searchBIRD

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4G5H	Crystal structure of capsular polysaccharide synthesizing enzyme CapE from Staphylococcus aureus in complex with by-product 分子名称: Capsular polysaccharide synthesis enzyme Cap8E, FORMIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Miyafusa, T, Caaveiro, J.M.M, Tanaka, Y, Tsumoto, K. 登録日 2012-07-18 公開日 2013-08-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Dynamic elements govern the catalytic activity of CapE, a capsular polysaccharide-synthesizing enzyme from Staphylococcus aureus. Febs Lett., 587, 2013
4I01	Structure of the mutant Catabolite gen activator protein V140L 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator 著者 Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M.J. 登録日 2012-11-16 公開日 2013-10-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. Plos Biol., 11, 2013
4I0A	structure of the mutant Catabolite gene activator protein V132A 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, GLYCEROL 著者 Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M.J. 登録日 2012-11-16 公開日 2013-10-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. Plos Biol., 11, 2013
4JPY	Iron and phenylalanine bound crystal structure of phenylalanine hydroxylase from Chromobacterium violaceum 分子名称: FE (III) ION, PHENYLALANINE, Phenylalanine-4-hydroxylase 著者 Ronau, J.A, Abu-Omar, M.M, Das, C. 登録日 2013-03-19 公開日 2013-08-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 An additional substrate binding site in a bacterial phenylalanine hydroxylase. Eur.Biophys.J., 42, 2013
4I0B	structure of the mutant Catabolite gene activator protein H160L 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator 著者 Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M.J. 登録日 2012-11-16 公開日 2013-10-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. Plos Biol., 11, 2013
4I09	structure of the mutant Catabolite gene activator protein V132L 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator 著者 Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M.J. 登録日 2012-11-16 公開日 2013-10-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. Plos Biol., 11, 2013
4HZF	structure of the wild type Catabolite gene Activator Protein 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, GLYCEROL, ... 著者 Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M. 登録日 2012-11-15 公開日 2013-10-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. Plos Biol., 11, 2013
4I02	structure of the mutant Catabolite gene activator protein V140A 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator 著者 Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M.J. 登録日 2012-11-16 公開日 2013-10-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. Plos Biol., 11, 2013
6H5H	A computationally designed dRP lyase domain reconstructed from two heterologous fragments 分子名称: polb4 著者 ElGamacy, M, Coles, M, Lupas, A.N. 登録日 2018-07-24 公開日 2018-12-12 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Asymmetric protein design from conserved supersecondary structures. J. Struct. Biol., 204, 2018
7AHN	Cryo-EM structure of F-actin stabilized by cis-optoJASP-8 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Pospich, S, Raunser, S. 登録日 2020-09-24 公開日 2021-01-27 最終更新日 2021-04-14 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States. Angew.Chem.Int.Ed.Engl., 60, 2021
7AHQ	Cryo-EM structure of F-actin stabilized by trans-optoJASP-8 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Pospich, S, Raunser, S. 登録日 2020-09-25 公開日 2021-01-27 最終更新日 2021-04-14 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States. Angew.Chem.Int.Ed.Engl., 60, 2021
6EXQ	Crystal Structure of Rhodesain in complex with a Macrolactam Inhibitor 分子名称: (3~{S})-19-chloranyl-~{N}-(1-cyanocyclopropyl)-8-methoxy-5-oxidanylidene-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(20),6(11),7,9,18,21-hexaene-3-carboxamide, 1,2-ETHANEDIOL, Cysteine protease 著者 Dietzel, U, Kisker, C. 登録日 2017-11-08 公開日 2018-04-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors. J. Med. Chem., 61, 2018
6HIK	X-ray structure of TEAD4(Y429H) mutant) complexed with YAP (wildtype): Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy 分子名称: MYRISTIC ACID, PHOSPHATE ION, Transcriptional coactivator YAP1, ... 著者 Kallen, J. 登録日 2018-08-30 公開日 2019-04-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy. Febs J., 286, 2019
5V7W	Crystal structure of human PARP14 bound to 2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one inhibitor 分子名称: 2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one, Poly [ADP-ribose] polymerase 14 著者 saikatendu, k.s, Hirozane, M. 登録日 2017-03-20 公開日 2017-05-10 最終更新日 2018-11-14 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Identification of PARP14 inhibitors using novel methods for detecting auto-ribosylation. Biochem. Biophys. Res. Commun., 486, 2017
6HIL	X-ray structure of TEAD1(Y421H mutant) complexed with YAP(wildtype): Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy 分子名称: MYRISTIC ACID, Transcriptional coactivator YAP1, Transcriptional enhancer factor TEF-1 著者 Kallen, J. 登録日 2018-08-30 公開日 2019-04-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy. Febs J., 286, 2019
5X8W	Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain. 分子名称: Nuclear receptor ROR-gamma, Nuclear receptor coactivator 1 著者 Noguchi, M, Nomura, A, Murase, K, Doi, S, Yamaguchi, K, Adachi, T. 登録日 2017-03-03 公開日 2017-06-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Ternary complex of human ROR gamma ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment Genes Cells, 22, 2017
5YQW	Structure and function of a novel periplasmic chitooligosaccharide-binding protein from marine Vibrio bacteria 分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NICKEL (II) ION, ... 著者 Suginta, W, Sritho, N, Ranok, A, Kitaoku, Y, Bulmer, D.M, van den Berg, B, Fukamizo, T. 登録日 2017-11-08 公開日 2018-02-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Structure and function of a novel periplasmic chitooligosaccharide-binding protein from marineVibriobacteria. J. Biol. Chem., 293, 2018
4AWB	Crystal structure of active legumain in complex with AAN-CMK 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEGUMAIN, MERCURY (II) ION, ... 著者 Dall, E, Brandstetter, H. 登録日 2012-06-01 公開日 2013-06-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation Proc.Natl.Acad.Sci.USA, 110, 2013
4AW9	Crystal structure of active legumain in complex with YVAD-CMK 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-TYR-VAL-ALA-ASP-CHLOROMETHYLKETONE, LEGUMAIN, ... 著者 Dall, E, Brandstetter, H. 登録日 2012-06-01 公開日 2013-06-26 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation Proc.Natl.Acad.Sci.USA, 110, 2013
4BH6	Insights into degron recognition by APC coactivators from the structure of an Acm1-Cdh1 complex 分子名称: APC/C ACTIVATOR PROTEIN CDH1, APC/C-CDH1 MODULATOR 1 著者 He, J, Chao, W.C.H, Zhang, Z, Yang, J, Cronin, N, Barford, D. 登録日 2013-03-29 公開日 2013-06-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insights Into Degron Recognition by Apc/C Coactivators from the Structure of an Acm1-Cdh1 Complex. Mol.Cell, 50, 2013
4AWA	Crystal structure of active legumain in complex with YVAD-CMK at pH 5.0 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEGUMAIN, SULFATE ION, ... 著者 Dall, E, Brandstetter, H. 登録日 2012-06-01 公開日 2013-06-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation Proc.Natl.Acad.Sci.USA, 110, 2013
4BYY	Apo GlxR 分子名称: GLYCEROL, PHOSPHATE ION, TRANSCRIPTIONAL REGULATOR, ... 著者 Pohl, E, Cann, M.J, Townsend, P.D, Money, V.A. 登録日 2013-07-21 公開日 2014-07-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 The Crystal Structures of Apo and Camp-Bound Glxr from Corynebacterium Glutamicum Reveal Structural and Dynamic Changes Upon Camp Binding in Crp/Fnr Family Transcription Factors. Plos One, 9, 2014
4BUR	Crystal structure of the reduced human Apoptosis inducing factor complexed with NAD 分子名称: APOPTOSIS INDUCING FACTOR 1, MITOCHONDRIAL, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Martinez-Julvez, M, Herguedas, B, Hermoso, J.A, Ferreira, P, Villanueva, R, Medina, M. 登録日 2013-06-23 公開日 2014-07-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Structural Insights Into the Coenzyme Mediated Monomer-Dimer Transition of the Pro-Apoptotic Apoptosis Inducing Factor. Biochemistry, 53, 2014
4MFK	The crystal structure of acyltransferase in complex with decanoyl-CoA 分子名称: Putative uncharacterized protein tcp24, SULFATE ION, decanoyl-CoA 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
4DOR	Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, in its apo State Bound to a Fragment of Human SHP Box1 分子名称: L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, Nuclear receptor subfamily 0 group B member 2, Nuclear receptor subfamily 5 group A member 2 著者 Musille, P.M, Ortlund, E.A. 登録日 2012-02-10 公開日 2012-04-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation. Nat.Struct.Mol.Biol., 19, 2012

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