2PKD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2pkd by Molmil](/molmil-images/mine/2pkd) | Crystal structure of CD84: Insite into SLAM family function | 分子名称: | CHLORIDE ION, SLAM family member 5 | 著者 | Yan, Q, Malashkevich, V.N, Fedorov, A, Cao, E, Lary, J.W, Cole, J.L, Nathenson, S.G, Almo, S.C. | 登録日 | 2007-04-17 | 公開日 | 2007-06-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.043 Å) | 主引用文献 | Structure of CD84 provides insight into SLAM family function. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
5DA4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5da4 by Molmil](/molmil-images/mine/5da4) | |
7LWD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lwd by Molmil](/molmil-images/mine/7lwd) | Cryo-EM structure of the wild-type human serotonin transporter complexed with vilazodone, imipramine and 15B8 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, 5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide, ... | 著者 | Yang, D, Kalenderoglou, I.E, Gouaux, E, Coleman, J.A, Loland, C.J. | 登録日 | 2021-03-01 | 公開日 | 2021-08-11 | 最終更新日 | 2021-09-01 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter. Nat Commun, 12, 2021
|
|
3M67
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3m67 by Molmil](/molmil-images/mine/3m67) | Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-5-[(6,7-dihydro-1H-[1,4]dioxino[2,3-f]benzimidazol-2-ylsulfanyl)acetyl]benzenesulfonamide | 分子名称: | 2-chloro-5-[(6,7-dihydro-1H-[1,4]dioxino[2,3-f]benzimidazol-2-ylsulfanyl)acetyl]benzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | 著者 | Grazulis, S, Manakova, E, Golovenko, D. | 登録日 | 2010-03-15 | 公開日 | 2010-11-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Indapamide-like benzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, and XIII Bioorg.Med.Chem., 18, 2010
|
|
1ULI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1uli by Molmil](/molmil-images/mine/1uli) | Biphenyl dioxygenase (BphA1A2) derived from Rhodococcus sp. strain RHA1 | 分子名称: | FE (II) ION, FE2/S2 (INORGANIC) CLUSTER, biphenyl dioxygenase large subunit, ... | 著者 | Furusawa, Y, Nagarajan, V, Masai, E, Tanokura, M, Fukuda, M, Senda, T. | 登録日 | 2003-09-12 | 公開日 | 2004-09-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of the Terminal Oxygenase Component of Biphenyl Dioxygenase Derived from Rhodococcus sp. Strain RHA1 J.Mol.Biol., 342, 2004
|
|
6FVW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fvw by Molmil](/molmil-images/mine/6fvw) | 26S proteasome, s4 state | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | 著者 | Eisele, M.R, Reed, R.G, Rudack, T, Schweitzer, A, Beck, F, Nagy, I, Pfeifer, G, Plitzko, J.M, Baumeister, W, Tomko, R.J, Sakata, E. | 登録日 | 2018-03-05 | 公開日 | 2018-08-29 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating. Cell Rep, 24, 2018
|
|
6R7G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r7g by Molmil](/molmil-images/mine/6r7g) | Atomic structure of potato virus X, the prototype of the Alphaflexiviridae family | 分子名称: | Coat protein, polyU RNA | 著者 | Grinzato, A, Kandiah, E, Lico, C, Betti, C, Baschieri, S, Zanotti, G. | 登録日 | 2019-03-28 | 公開日 | 2020-03-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Atomic structure of potato virus X, the prototype of the Alphaflexiviridae family. Nat.Chem.Biol., 16, 2020
|
|
8AEM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8aem by Molmil](/molmil-images/mine/8aem) | Structure of Compound 13 bound to CK2alpha | 分子名称: | 2-(5-chloranyl-1H-indol-3-yl)ethanenitrile, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Brear, P, Fusco, C, Atkinson, E, Iegre, J, Francis-Newton, N, Venkotaraman, A, Spring, D, Hyvonen, M. | 登録日 | 2022-07-13 | 公開日 | 2023-03-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A fragment-based approach leading to the discovery of inhibitors of CK2 alpha with a novel mechanism of action. Rsc Med Chem, 13, 2022
|
|
1GTV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1gtv by Molmil](/molmil-images/mine/1gtv) | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH THYMIDINE-5'-DIPHOSPHATE (TDP) | 分子名称: | ACETATE ION, MAGNESIUM ION, SULFATE ION, ... | 著者 | Ursby, T, Weik, M, Fioravanti, E, Delarue, M, Goeldner, M, Bourgeois, D. | 登録日 | 2002-01-21 | 公開日 | 2002-03-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Cryophotolysis of Caged Compounds: A Technique for Trapping Intermediate States in Protein Crystals Acta Crystallogr.,Sect.D, 58, 2002
|
|
2PPF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ppf by Molmil](/molmil-images/mine/2ppf) | |
6R7Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r7z by Molmil](/molmil-images/mine/6r7z) | CryoEM structure of calcium-free human TMEM16K / Anoctamin 10 in detergent (closed form) | 分子名称: | Anoctamin-10 | 著者 | Pike, A.C.W, Bushell, S.R, Shintre, C.A, Tessitore, A, Chu, A, Mukhopadhyay, S, Shrestha, L, Chalk, R, Burgess-Brown, N.A, Love, J, Huiskonen, J.T, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2019-03-29 | 公開日 | 2019-05-01 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (5.14 Å) | 主引用文献 | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K. Nat Commun, 10, 2019
|
|
3M2N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3m2n by Molmil](/molmil-images/mine/3m2n) | Crystal structure of human carbonic anhydrase isozyme II with 4-{2-[N-(6-chloro-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonamide | 分子名称: | 4-{2-[(6-chloro-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... | 著者 | Grazulis, S, Manakova, E, Golovenko, D. | 登録日 | 2010-03-08 | 公開日 | 2011-02-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
|
|
7LKO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lko by Molmil](/molmil-images/mine/7lko) | |
6HQE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hqe by Molmil](/molmil-images/mine/6hqe) | Cryo-EM of self-assembly peptide filament LRV_M3delta1 | 分子名称: | peptide LRV_M3delta1 | 著者 | Osinski, T, Wang, F, Hughes, S.A, Kreutzberger, M.A.B, Conticello, V.P, Egelman, E.H. | 登録日 | 2018-09-24 | 公開日 | 2019-06-26 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Ambidextrous helical nanotubes from self-assembly of designed helical hairpin motifs. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
5NWP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nwp by Molmil](/molmil-images/mine/5nwp) | |
7LKN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lkn by Molmil](/molmil-images/mine/7lkn) | |
5NXD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nxd by Molmil](/molmil-images/mine/5nxd) | LIM Domain Kinase 2 (LIMK2) In Complex With TH-300 | 分子名称: | 1,2-ETHANEDIOL, 4-[(3-chlorophenyl)sulfamoyl]-~{N}-(phenylmethyl)-~{N}-propyl-benzamide, LIM domain kinase 2 | 著者 | Mathea, S, Salah, E, Hanke, T, Newman, J.A, Oerum, S, Wang, D, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N, Knapp, S. | 登録日 | 2017-05-10 | 公開日 | 2017-05-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | LIM Domain Kinase 2 (LIMK2)In Complex With TH-300 To Be Published
|
|
5NS5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ns5 by Molmil](/molmil-images/mine/5ns5) | Cys-Gly dipeptidase GliJ in complex with Cu2+ and Zn2+ | 分子名称: | CHLORIDE ION, COPPER (II) ION, Dipeptidase gliJ, ... | 著者 | Groll, M, Huber, E.M. | 登録日 | 2017-04-25 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ. ACS Chem. Biol., 12, 2017
|
|
4DTD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4dtd by Molmil](/molmil-images/mine/4dtd) | Structure and functional characterization of a Vibrio cholerae toxin from the MARTX/VgrG family. | 分子名称: | GLYCEROL, VgrG protein | 著者 | Durand, E, Audoly, G, Derrez, E, Spinelli, S, Ortiz-Lombardia, M, Cascales, E, Raoult, D, Cambillau, C. | 登録日 | 2012-02-21 | 公開日 | 2012-08-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure and functional characterization of a Vibrio cholerae toxin
from the MARTX/VgrG family. J.Biol.Chem., 2012
|
|
5NSC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nsc by Molmil](/molmil-images/mine/5nsc) | Fc DEKK heterodimer variant | 分子名称: | Fc-III peptide, GLYCEROL, Putative uncharacterized protein DKFZp686C11235, ... | 著者 | De Nardis, C, Hendriks, L.J.A, Poirier, E, Arvinte, T, Gros, P, Bakker, A.B.H, de Kruif, J. | 登録日 | 2017-04-26 | 公開日 | 2017-07-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G1. J. Biol. Chem., 292, 2017
|
|
1HAF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1haf by Molmil](/molmil-images/mine/1haf) | |
1HAE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hae by Molmil](/molmil-images/mine/1hae) | |
4E36
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e36 by Molmil](/molmil-images/mine/4e36) | Crystal structure of the human Endoplasmic Reticulum Aminopeptidase 2 variant N392K | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Birtley, J.R, Saridakis, E, Pegias, P, Stratikos, E, Mavridis, I.M. | 登録日 | 2012-03-09 | 公開日 | 2012-08-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing. J.Immunol., 189, 2012
|
|
5DGG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dgg by Molmil](/molmil-images/mine/5dgg) | Central domain of uncharacterized Lpg1148 protein from Legionella pneumophila | 分子名称: | CHLORIDE ION, Uncharacterized protein | 著者 | Osipiuk, J, Evdokimova, E, Yim, V, Joachimiak, A, Ensminger, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-08-27 | 公開日 | 2015-09-16 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol. Syst. Biol., 12, 2016
|
|
7LKM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lkm by Molmil](/molmil-images/mine/7lkm) | |