PDB: 230764 件ウェブページステータス検索Chemie searchBIRD

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8E18	Crystal structure of apo TnmK1 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Secreted hydrolase 著者 Liu, Y.-C, Gui, C, Shen, B. 登録日 2022-08-10 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis. J.Am.Chem.Soc., 144, 2022
8DR3	Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD 分子名称: DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ... 著者 Schrecker, M, Hite, R.K. 登録日 2022-07-20 公開日 2022-08-17 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
8E19	Crystal structure of TnmK1 complexed with TNM H 分子名称: (1R,8S,13S)-8-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-12-methoxy-10-methylbicyclo[7.3.1]trideca-9,11-diene-2,6-diyne-13-carbaldehyde, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SUCCINIC ACID, ... 著者 Liu, Y.-C, Gui, C, Shen, B. 登録日 2022-08-10 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis. J.Am.Chem.Soc., 144, 2022
8DR1	Consensus closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) 分子名称: DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ... 著者 Schrecker, M, Hite, R.K. 登録日 2022-07-20 公開日 2022-08-17 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (2.14 Å) 主引用文献 Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
8DR5	Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD 分子名称: DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... 著者 Schrecker, M, Hite, R.K. 登録日 2022-07-20 公開日 2022-08-17 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
6M3B	hAPC-c25k23 Fab complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Vitamin K-dependent protein C heavy chain, Vitamin K-dependent protein C light chain, ... 著者 Wang, X, Li, L, Zhao, X, Egner, U. 登録日 2020-03-03 公開日 2020-07-08 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia. Nat Commun, 11, 2020
2DGZ	Solution structure of the Helicase and RNase D C-terminal domain in Werner syndrome ATP-dependent helicase 分子名称: Werner syndrome protein variant 著者 Abe, C, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-03-16 公開日 2006-09-16 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the Helicase and RNase D C-terminal domain in Werner syndrome ATP-dependent helicase To be Published
394D	CRYSTAL STRUCTURE OF TWO SELF-COMPLEMENTARY CHIMERIC DECAMERS D(CCGG)R(C)D(GCCGG) AND D(CCGG)R(CG)D(CCGG) 分子名称: DNA/RNA (5'-D(*CP*CP*GP*GP)-R(*CP*GP)-D(*CP*CP*GP*G)-3') 著者 Ban, C, Sundaralingam, M. 登録日 1998-04-29 公開日 1998-05-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of Two Self-Complementary Chimeric Decamers d(CCGG)r(C)d(GCCGG) and d(CCGG)r(CG)d(CCGG) To be Published
393D	CRYSTAL STRUCTURE OF TWO SELF-COMPLEMENTARY CHIMERIC DECAMER D(CCGG)R(C)D(GCCGG) AND D(CCGG)R(CG)D(CCGG) 分子名称: DNA/RNA (5'-D(*CP*CP*GP*GP)-R(*CP)-D(*GP*CP*CP*GP*G)-3') 著者 Ban, C, Sundaralingam, M, Ramakrishnan, B. 登録日 1998-04-29 公開日 1998-05-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Two Self-Complementary Chimeric Decamer d(CCGG)r(C)d(GCCGG) and d(CCGG)r(CG)d(CCGG) To be Published
2XXI	Crystal structure of 1-((4-(3-(trifluoromethyl)-6,7-dihydropyrano(4,3- c(pyrazol-1(4H)-yl)phenyl)methyl)-2-pyrrolidinone in complex with the ligand binding domain of the Rat GluA2 receptor and glutamate at 1.6A resolution. 分子名称: 1-({4-[3-(TRIFLUOROMETHYL)-6,7-DIHYDROPYRANO[4,3-C]PYRAZOL-1(4H)-YL]PHENYL}METHYL)-2-PYRROLIDINONE, GLUTAMATE RECEPTOR 2, GLUTAMIC ACID, ... 著者 Ward, S.E, Harries, M, Aldegheri, L, Austin, N.E, Ballantine, S, Ballini, E, Bradley, D.M, Bax, B.D, Clarke, B.P, Harris, A.J, Harrison, S.A, Melarange, R.A, Mookherjee, C, Mosley, J, DalNegro, G, Oliosi, B, Smith, K.J, Thewlis, K.M, Woollard, P.M, Yusaf, S.P. 登録日 2010-11-10 公開日 2011-04-06 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of Ampa Receptor Positive Allosteric Modulators. J.Med.Chem., 54, 2011
4EXK	A chimera protein containing MBP fused to the C-terminal domain of the uncharacterized protein STM14_2015 from Salmonella enterica 分子名称: Maltose-binding periplasmic protein, uncharacterized protein chimera, TRIETHYLENE GLYCOL, ... 著者 Nocek, B, Hatzos-Skintges, C, Jedrzejczak, R, Babnigg, G, Brown, R.N, Cort, J.R, Heffron, F, Nakayasu, E.S, Adkins, J.N, Joachimiak, A, Program for the Characterization of Secreted Effector Proteins (PCSEP), Midwest Center for Structural Genomics (MCSG) 登録日 2012-04-30 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 A chimera protein containing MBP fused to the C-terminal domain of the uncharacterized protein STM14_2015 form Salmonella enterica To be Published
2LSY	Structure of the C-terminal domain from human REV1 分子名称: DNA repair protein REV1 著者 Pozhidaeva, A, Pustovalova, Y, Bezsonova, I, Korzhnev, D. 登録日 2012-05-09 公開日 2012-06-27 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase eta. Biochemistry, 51, 2012
1YNE	NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor 分子名称: APOLIPOPROTEIN B mRNA 著者 Maris, C, Masse, J, Allain, F.H, Chester, A, Navaratnam, N. 登録日 2005-01-24 公開日 2005-02-08 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor. Rna, 11, 2005
1YNG	NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor 分子名称: apolipoprotein B mRNA 著者 Maris, C, Masse, J, Allain, F.H, Chester, A, Navaratnam, N. 登録日 2005-01-24 公開日 2005-02-08 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor. Rna, 11, 2005
3FQQ	Crystal structure of a novel dimeric form of HCV NS5A domain I protein 分子名称: 3-methyl-1-(2-methylpropyl)butyl 4-O-beta-L-gulopyranosyl-beta-D-glucopyranoside, GLYCEROL, Non-structural protein 5A, ... 著者 Love, R.A. 登録日 2009-01-07 公開日 2009-03-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a novel dimeric form of NS5A domain I protein from hepatitis C virus J.Virol., 83, 2009
3FQM	Crystal structure of a novel dimeric form of HCV NS5A domain I protein 分子名称: GLYCEROL, Non-structural protein 5A, ZINC ION 著者 Love, R.A. 登録日 2009-01-07 公開日 2009-03-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a novel dimeric form of NS5A domain I protein from hepatitis C virus J.Virol., 83, 2009
1NLB	crystal structure of anti-HCV monoclonal antibody 19D9D6 分子名称: antibody 19D9D6 heavy chain, antibody 19D9D6 light chain 著者 Menez, R, Bossus, M, Muller, B, Sibai, G, Dalbon, P, Ducancel, F, Jolivet-Reynaud, C, Stura, E. 登録日 2003-01-07 公開日 2003-02-25 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of a hydrophobic immunodominant antigenic site on hepatitis C virus core protein complexed to monoclonal antibody 19D9D6. J.Immunol., 170, 2003
2YLF	Crystal structure of the human Spir-1 KIND domain 分子名称: PROTEIN SPIRE HOMOLOG 1 著者 Zeth, K, Pechlivanis, M, Vonrhein, C, Kerkhoff, E. 登録日 2011-06-01 公開日 2011-06-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Molecular Basis of Actin Nucleation Factor Cooperativity: Crystal Structure of the Spir-1 Kinase Non-Catalytic C-Lobe Domain (Kind)Formin-2 Formin Spir Interaction Motif (Fsi) Complex. J.Biol.Chem., 286, 2011
3AM1	Crystal structure of O-Phosphoseryl-tRNA kinase complexed with anticodon-stem/loop truncated tRNA(Sec) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ASL-truncated tRNA, L-seryl-tRNA(Sec) kinase, ... 著者 Araiso, Y, Ishitani, R, Nureki, O. 登録日 2010-08-11 公開日 2010-12-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 C-terminal domain of archaeal O-phosphoseryl-tRNA kinase displays large-scale motion to bind the 7-bp D-stem of archaeal tRNA(Sec) Nucleic Acids Res., 39, 2011
4PMS	The structure of TrkA kinase bound to the inhibitor 4-naphthalen-1-yl-1-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid 分子名称: 4-(naphthalen-1-yl)-1-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid, ACETATE ION, CHLORIDE ION, ... 著者 Su, H.P. 登録日 2014-05-22 公開日 2014-06-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain. J.Med.Chem., 57, 2014
4H39	Crystal Structure of JNK3 in Complex with JIP1 Peptide 分子名称: C-Jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 10 著者 Nwachukwu, J.C, Laughlin, J.D, Figuera-Losada, M, Cherry, L, Nettles, K.W, LoGrasso, P.V. 登録日 2012-09-13 公開日 2012-11-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.992 Å) 主引用文献 Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases. Structure, 20, 2012
1LVF	syntaxin 6 分子名称: syntaxin 6 著者 Misura, K.M.S, Bock, J.B, Gonzalez, L.C, Scheller, R.H, Weis, W.I. 登録日 2002-05-28 公開日 2002-07-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog. Proc.Natl.Acad.Sci.USA, 99, 2002
6ITU	Crystal Structure of the GULP1 PTB domain-APP peptide complex 分子名称: 1,2-ETHANEDIOL, Amyloid beta A4 protein, PTB domain-containing engulfment adapter protein 1, ... 著者 Yung, K.W.Y, Lau, K.F, Ngo, J.C.K. 登録日 2018-11-26 公開日 2019-08-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Attenuation of amyloid-beta generation by atypical protein kinase C-mediated phosphorylation of engulfment adaptor PTB domain containing 1 threonine 35. Faseb J., 33, 2019
2XWH	HCV-J6 NS5B polymerase structure at 1.8 Angstrom 分子名称: DI(HYDROXYETHYL)ETHER, POLYETHYLENE GLYCOL (N=34), RNA DEPENDENT RNA POLYMERASE 著者 Scrima, N, Bressanelli, S. 登録日 2010-11-03 公開日 2011-01-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strains Jfh1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture Across Genotypes. J.Virol., 85, 2011
7L7P	Crystal structure of HCV NS3/4A D168A protease in complex with CH-24 分子名称: 1,2-ETHANEDIOL, NS3/4A protease, SULFATE ION, ... 著者 Zephyr, J, Schiffer, C.A. 登録日 2020-12-29 公開日 2021-09-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants. J.Med.Chem., 64, 2021

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