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8THC
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BU of 8thc by Molmil
Structure of the Saccharomyces cerevisiae clamp unloader Elg1-RFC bound to a cracked PCNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, ELG1 isoform 1, MAGNESIUM ION, ...
著者Zheng, F, Yao, Y.N, Georgescu, R, O'Donnell, M.E, Li, H.
登録日2023-07-14
公開日2024-05-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Structure of the PCNA unloader Elg1-RFC.
Sci Adv, 10, 2024
8THD
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BU of 8thd by Molmil
Structure of the Saccharomyces cerevisiae clamp unloader Elg1-RFC bound to PCNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, ELG1 isoform 1, MAGNESIUM ION, ...
著者Zheng, F, Yao, Y.N, Georgescu, R, O'Donnell, M.E, Li, H.
登録日2023-07-14
公開日2024-05-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structure of the PCNA unloader Elg1-RFC.
Sci Adv, 10, 2024
8A31
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BU of 8a31 by Molmil
p53 cancer mutant Y220C in complex with iodophenol-based small-molecule stabilizer JC694
分子名称: 4-(3-fluoranylpyrrol-1-yl)-3,5-bis(iodanyl)-2-oxidanyl-benzoic acid, Cellular tumor antigen p53, GLYCEROL, ...
著者Balourdas, D.I, Stephenson Clarke, J.R, Baud, M.G.J, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC)
登録日2022-06-06
公開日2022-11-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Discovery of Nanomolar-Affinity Pharmacological Chaperones Stabilizing the Oncogenic p53 Mutant Y220C.
Acs Pharmacol Transl Sci, 5, 2022
8A32
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BU of 8a32 by Molmil
p53 cancer mutant Y220C in complex with iodophenol-based small-molecule stabilizer JC769
分子名称: 1,2-ETHANEDIOL, 4-[3,4-bis(fluoranyl)pyrrol-1-yl]-3,5-bis(iodanyl)-2-oxidanyl-benzoic acid, Cellular tumor antigen p53, ...
著者Balourdas, D.I, Stephenson Clarke, J.R, Baud, M.G.J, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC)
登録日2022-06-06
公開日2022-11-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Discovery of Nanomolar-Affinity Pharmacological Chaperones Stabilizing the Oncogenic p53 Mutant Y220C.
Acs Pharmacol Transl Sci, 5, 2022
7O9K
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BU of 7o9k by Molmil
Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the MALSU module, GTPBP5 and mtEF-Tu
分子名称: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
著者Valentin Gese, G, Hallberg, B.M.
登録日2021-04-16
公開日2021-06-30
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for late maturation steps of the human mitoribosomal large subunit.
Nat Commun, 12, 2021
2VT2
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BU of 2vt2 by Molmil
Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, REDOX-SENSING TRANSCRIPTIONAL REPRESSOR REX
著者Wang, E, Bauer, M.C, Rogstam, A, Linse, S, Logan, D.T, von Wachenfeldt, C.
登録日2008-05-08
公開日2008-09-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex.
Mol. Microbiol., 69, 2008
2NS8
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BU of 2ns8 by Molmil
How an in vitro selected peptide mimics the antibiotic tetracycline to induce TET repressor
分子名称: 16 residue peptide Tip (Transcription inducing peptide), Tetracycline repressor protein
著者Luckner, S.R, Klotzsche, M, Berens, C, Hillen, W, Muller, Y.A.
登録日2006-11-03
公開日2007-07-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献How an agonist peptide mimics the antibiotic tetracycline to induce Tet-repressor
J.Mol.Biol., 368, 2007
6O09
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BU of 6o09 by Molmil
Structure of AtPCNA in complex with the PIP motif of ATXR6
分子名称: Proliferating cellular nuclear antigen 1, Uncharacterized protein
著者Couture, J.F, Davarinejad, H.
登録日2019-02-15
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献ATXR5/6 Forms Alternative Protein Complexes with PCNA and the Nucleosome Core Particle.
J. Mol. Biol., 431, 2019
7TRD
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BU of 7trd by Molmil
Human telomerase catalytic core structure at 3.3 Angstrom
分子名称: Telomerase RNA, partial sequence, Telomerase reverse transcriptase, ...
著者Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J.
登録日2022-01-28
公開日2022-04-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
2NS7
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BU of 2ns7 by Molmil
How an in vitro selected peptide mimics the antibiotic tetracycline to induce TET repressor
分子名称: Tetracycline repressor protein
著者Luckner, S.R, Klotzsche, M, Berens, C, Hillen, W, Muller, Y.A.
登録日2006-11-03
公開日2007-07-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献How an agonist peptide mimics the antibiotic tetracycline to induce Tet-repressor
J.Mol.Biol., 368, 2007
1B9N
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BU of 1b9n by Molmil
REGULATOR FROM ESCHERICHIA COLI
分子名称: NICKEL (II) ION, PROTEIN (MODE)
著者Hall, D.R, Gourley, D.G, Hunter, W.N.
登録日1999-02-12
公開日2000-03-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The high-resolution crystal structure of the molybdate-dependent transcriptional regulator (ModE) from Escherichia coli: a novel combination of domain folds.
EMBO J., 18, 1999
1B9M
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BU of 1b9m by Molmil
REGULATOR FROM ESCHERICHIA COLI
分子名称: NICKEL (II) ION, PROTEIN (MODE)
著者Hall, D.R, Gourley, D.G, Hunter, W.N.
登録日1999-02-12
公開日2000-03-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The high-resolution crystal structure of the molybdate-dependent transcriptional regulator (ModE) from Escherichia coli: a novel combination of domain folds.
EMBO J., 18, 1999
2Q0O
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BU of 2q0o by Molmil
Crystal structure of an anti-activation complex in bacterial quorum sensing
分子名称: 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, Probable transcriptional activator protein traR, Probable transcriptional repressor traM
著者Chen, G, Jeffrey, P.D, Fuqua, C, Shi, Y, Chen, L.
登録日2007-05-22
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for antiactivation in bacterial quorum sensing.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2XDI
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BU of 2xdi by Molmil
Tryptophan repressor with L75F mutation in its apo form (no L- tryptophan bound)
分子名称: TRP OPERON REPRESSOR
著者Tyler, R, Copie, V.
登録日2010-05-03
公開日2010-07-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Three-Dimensional Solution NMR Structure of Apo-L75F-Trpr, a Temperature-Sensitive Mutant of the Tryptophan Repressor Protein.
Biochemistry, 41, 2002
6RMQ
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BU of 6rmq by Molmil
Crystal structure of a selenomethionine-substituted A70M I84M mutant of the essential repressor DdrO from radiation resistant-Deinococcus bacteria (Deinococcus deserti)
分子名称: HTH-type transcriptional regulator DdrOC
著者Arnoux, P, Siponen, M.I, Pignol, D, De Groot, A, Blanchard, L.
登録日2019-05-07
公開日2019-10-09
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the transcriptional repressor DdrO: insight into the metalloprotease/repressor-controlled radiation response in Deinococcus.
Nucleic Acids Res., 47, 2019
5EF3
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BU of 5ef3 by Molmil
RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 25.0 MGy
分子名称: (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB
著者Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B.
登録日2015-10-23
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
5EF1
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BU of 5ef1 by Molmil
RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 19.3 MGy
分子名称: (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB
著者Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B.
登録日2015-10-23
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
5EEW
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BU of 5eew by Molmil
RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 6.45 MGy
分子名称: (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB
著者Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B.
登録日2015-10-23
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
5EF2
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BU of 5ef2 by Molmil
RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 21.9 MGy
分子名称: (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB
著者Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B.
登録日2015-10-23
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
5EEV
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BU of 5eev by Molmil
RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 3.88 MGy
分子名称: (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB
著者Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B.
登録日2015-10-23
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
5EEX
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BU of 5eex by Molmil
RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 9.02 MGy
分子名称: (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB
著者Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B.
登録日2015-10-23
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
6YHZ
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BU of 6yhz by Molmil
UvrD helicase RNA polymerase interactions are governed by UvrDs carboxy terminal Tudor domain.
分子名称: Transcription-repair-coupling factor
著者Kawale, A.A, Burmann, B.B.
登録日2020-03-31
公開日2020-10-21
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献UvrD helicase-RNA polymerase interactions are governed by UvrD's carboxy-terminal Tudor domain.
Commun Biol, 3, 2020
5MSM
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BU of 5msm by Molmil
Structure of the Dcc1-Ctf8-Ctf18C Trimer
分子名称: Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, Sister chromatid cohesion protein DCC1
著者Wade, B.O, Singleton, M.R.
登録日2017-01-05
公開日2017-02-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural studies of RFC(C)(tf18) reveal a novel chromatin recruitment role for Dcc1.
EMBO Rep., 18, 2017
6YVD
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BU of 6yvd by Molmil
Head segment of the S.cerevisiae condensin holocomplex in presence of ATP
分子名称: Condensin complex subunit 2, Condensin complex subunit 3, Structural maintenance of chromosomes protein 2, ...
著者Merkel, F, Haering, C.H, Hassler, M, Lee, B.G, Lowe, J.
登録日2020-04-28
公開日2020-07-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
Nat.Struct.Mol.Biol., 27, 2020
6N0R
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BU of 6n0r by Molmil
Crystal structure of Tdp1 catalytic domain in complex with compound XZ572
分子名称: 1,2-ETHANEDIOL, 4-(methylamino)benzene-1,2-dicarboxylic acid, DIMETHYL SULFOXIDE, ...
著者Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Burke Jr, T.R, Pommier, Y, Waugh, D.S.
登録日2018-11-07
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.544 Å)
主引用文献Crystal structure of Tdp1 catalytic domain
To Be Published

224572

件を2024-09-04に公開中

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