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4YWL
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Pyrococcus furiosus MCM N-terminal domain F179A point mutant pentameric ring
分子名称: Cell division control protein 21, SULFATE ION, ZINC ION
著者Froelich, C.A, Enemark, E.J.
登録日2015-03-20
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献MCM ring hexamerization is a prerequisite for DNA-binding.
Nucleic Acids Res., 43, 2015
2X9A
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BU of 2x9a by Molmil
crystal structure of g3p from phage IF1 in complex with its coreceptor, the C-terminal domain of TolA
分子名称: ATTACHMENT PROTEIN G3P, MEMBRANE SPANNING PROTEIN, REQUIRED FOR OUTER MEMBRANE INTEGRITY
著者Lorenz, S.H, Jakob, R.P, Dobbek, H, Schmid, F.X.
登録日2010-03-15
公開日2010-12-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献The Filamentous Phages Fd and If1 Use Different Mechanisms to Infect Escherichia Coli.
J.Mol.Biol., 405, 2011
7AQK
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BU of 7aqk by Molmil
Model of the actin filament Arp2/3 complex branch junction in cells
分子名称: Actin, alpha skeletal muscle, ACTA1, ...
著者Faessler, F, Dimchev, G, Hodirnau, V.V, Wan, W, Schur, F.K.M.
登録日2020-10-22
公開日2020-12-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction.
Nat Commun, 11, 2020
7AST
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BU of 7ast by Molmil
Apo Human RNA Polymerase III
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Ramsay, E.P, Abascal-Palacios, G, Daiss, J.L, King, H, Gouge, J, Pilsl, M, Beuron, F, Morris, E, Gunkel, P, Engel, C, Vannini, A.
登録日2020-10-28
公開日2020-12-23
最終更新日2020-12-30
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of human RNA polymerase III.
Nat Commun, 11, 2020
6S68
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BU of 6s68 by Molmil
Structure of the Fluorescent Protein AausFP2 from Aequorea cf. australis at pH 7.6
分子名称: Aequorea cf. australis fluorescent protein 2 (AausFP2)
著者Depernet, H, Gotthard, G, Lambert, G.G, Shaner, N.C, Royant, A.
登録日2019-07-02
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Aequorea's secrets revealed: New fluorescent proteins with unique properties for bioimaging and biosensing.
Plos Biol., 18, 2020
7AER
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BU of 7aer by Molmil
Rebuilt and re-refined PDB entry 5yep: tri-AMPylated Shewanella oneidensis HEPN toxin in complex with MNT antitoxin
分子名称: ADENOSINE MONOPHOSPHATE, Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family
著者Tamulaitiene, G, Sasnauskas, G, Songailiene, I, Juozapaitis, J, Siksnys, V.
登録日2020-09-18
公開日2020-12-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation.
Mol.Cell, 80, 2020
7B2X
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BU of 7b2x by Molmil
Crystal structure of human 5' exonuclease Appollo H61Y variant
分子名称: 5' exonuclease Apollo, NICKEL (II) ION
著者Newman, J.A, Baddock, H.T, Mukhopadhyay, S.M.M, Burgess-Brown, N.A, von Delft, F, Arrowshmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2020-11-28
公開日2021-01-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family.
Nucleic Acids Res., 49, 2021
7X9F
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BU of 7x9f by Molmil
Crystal structure of actinomycin D-echinomycin-d(AGCGCGT/ACGCGCT) complex
分子名称: 2-CARBOXYQUINOXALINE, DNA (5'-D(P*AP*CP*GP*CP*GP*CP*T)-3'), DNA (5'-D(P*AP*GP*CP*GP*CP*GP*T)-3'), ...
著者Kao, S.H, Satange, R.B, Hou, M.H.
登録日2022-03-15
公開日2022-12-14
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
7X6R
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BU of 7x6r by Molmil
Crystal structure of actinomycin D-echinomycin-d(AGCACGT/ACGGGCT) complex
分子名称: 2-CARBOXYQUINOXALINE, Actinomycin D, COBALT (II) ION, ...
著者Kao, S.H, Satange, R.B, Hou, M.H.
登録日2022-03-08
公開日2022-12-14
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
7X97
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BU of 7x97 by Molmil
Crystal structure of actinomycin D-echinomycin-d(AGCCCGT/ACGGGCT) complex
分子名称: 2-CARBOXYQUINOXALINE, Actinomycin D, CHLORIDE ION, ...
著者Kao, S.H, Satange, R.B, Hou, M.H.
登録日2022-03-15
公開日2022-12-14
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
7XDJ
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BU of 7xdj by Molmil
Crystal structure of actinomycin D-echinomycin-d(AGCGCGT/ACGAGCT) complex
分子名称: 2-CARBOXYQUINOXALINE, CHLORIDE ION, DNA (5'-D(P*AP*CP*GP*AP*GP*CP*(BRU))-3'), ...
著者Chien, C.M, Satange, R.B, Hou, M.H.
登録日2022-03-27
公開日2022-12-14
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.435 Å)
主引用文献Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
7X1R
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BU of 7x1r by Molmil
Cryo-EM structure of human thioredoxin reductase bound by Au
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION, Thioredoxin reductase 1, ...
著者He, Z.S, Cao, P, Cao, S.H, He, B, Jiang, H.D, Gong, Y, Gao, X.Y.
登録日2022-02-24
公開日2022-12-14
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Au4 cluster inhibits human thioredoxin reductase activity via specifically binding of Au to Cys189
Nano Today, 47, 2022
5FKJ
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BU of 5fkj by Molmil
Crystal structure of mouse acetylcholinesterase in complex with C-547, an alkyl ammonium derivative of 6-methyl uracil
分子名称: 1,3-BIS[5(DIETHYL-O-NITROBENZYLAMMONIUM)PENTYL]-6-METHYLURACIL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ...
著者Nachon, F, Villard-Wandhammer, M, Petrov, K, Masson, P.
登録日2015-10-16
公開日2016-03-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.133 Å)
主引用文献Slow-Binding Inhibition of Acetylcholinesterase by a 6-Methyluracil Alkyl-Ammonium Derivative: Mechanism and Advantages for Myasthenia Gravis Treatment.
Biochem.J., 473, 2016
4ZQQ
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BU of 4zqq by Molmil
Apo form of influenza strain H1N1 polymerase acidic subunit N-terminal region
分子名称: MANGANESE (II) ION, Polymerase acidic protein,Polymerase acidic protein, SULFATE ION
著者Fudo, S, Yamamoto, N, Nukaga, M, Odagiri, T, Tashiro, M, Neya, S, Hoshino, T.
登録日2015-05-11
公開日2015-06-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Two Distinctive Binding Modes of Endonuclease Inhibitors to the N-Terminal Region of Influenza Virus Polymerase Acidic Subunit.
Biochemistry, 55, 2016
3O9R
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BU of 3o9r by Molmil
Effector domain of NS1 from influenza A/PR/8/34 containing a W187A mutation
分子名称: Nonstructural protein 1
著者Kerry, P.S, Lewis, A, Hale, B.G, Hass, C, Taylor, M.A, Randall, R.E, Russell, R.J.M.
登録日2010-08-04
公開日2011-05-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain.
Plos One, 6, 2011
1LBC
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BU of 1lbc by Molmil
Crystal structure of GluR2 ligand binding core (S1S2J-N775S) in complex with cyclothiazide (CTZ) as well as glutamate at 1.8 A resolution
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamine Receptor 2, ...
著者Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E.
登録日2002-04-02
公開日2002-05-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
1LBB
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BU of 1lbb by Molmil
Crystal structure of the GluR2 ligand binding domain mutant (S1S2J-N754D) in complex with kainate at 2.1 A resolution
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamine receptor 2
著者Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E.
登録日2002-04-02
公開日2002-06-05
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
7WY4
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BU of 7wy4 by Molmil
Structure of the CYP102A1 F87A Haem Domain with N-Enanthyl-L-Prolyl-L-Phenylalanine in complex with Styrene
分子名称: (2S)-2-[[(2S)-1-heptylpyrrolidin-2-yl]carbonylamino]-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, CHLORIDE ION, ...
著者Suzuki, K, Stanfield, J.K, Shisaka, Y, Omura, K, Kasai, C, Sugimoto, H, Shoji, O.
登録日2022-02-15
公開日2023-01-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations.
Angew.Chem.Int.Ed.Engl., 62, 2023
7WY3
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Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 F87V Mutant Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with Styrene
分子名称: (2~{S})-2-(5-cyclohexylpentanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, CHLORIDE ION, ...
著者Suzuki, K, Stanfield, J.K, Shisaka, Y, Omura, K, Kasai, C, Sugimoto, H, Shoji, O.
登録日2022-02-15
公開日2023-01-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations.
Angew.Chem.Int.Ed.Engl., 62, 2023
4ZI0
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Endonuclease inhibitor bound to influenza strain H1N1 polymerase acidic subunit N-terminal region without a chelation to the metal ions in the active site
分子名称: 4-{(E)-[2-(4-chlorophenyl)hydrazinylidene]methyl}benzene-1,2,3-triol, MANGANESE (II) ION, Polymerase acidic protein, ...
著者Fudo, S, Yamamoto, N, Nukaga, M, Odagiri, T, Tashiro, M, Neya, S, Hoshino, T.
登録日2015-04-27
公開日2015-05-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Two Distinctive Binding Modes of Endonuclease Inhibitors to the N-Terminal Region of Influenza Virus Polymerase Acidic Subunit
Biochemistry, 55, 2016
7WY2
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BU of 7wy2 by Molmil
Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 F87A Mutant Haem Domain with N-Enanthyl-L-Prolyl-L-Phenylalanine in complex with Styrene
分子名称: (2S)-2-[[(2S)-1-heptylpyrrolidin-2-yl]carbonylamino]-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, CHLORIDE ION, ...
著者Suzuki, K, Stanfield, J.K, Shisaka, Y, Omura, K, Kasai, C, Sugimoto, H, Shoji, O.
登録日2022-02-15
公開日2023-01-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations.
Angew.Chem.Int.Ed.Engl., 62, 2023
7WY1
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BU of 7wy1 by Molmil
Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 Haem Domain with N-Enanthyl-L-Prolyl-L-Phenylalanine in complex with Styerene
分子名称: (2S)-2-[[(2S)-1-heptylpyrrolidin-2-yl]carbonylamino]-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, Oxomolybdenum Mesoporphyrin IX, ...
著者Suzuki, K, Stanfield, J.K, Shisaka, Y, Omura, K, Kasai, C, Sugimoto, H, Shoji, O.
登録日2022-02-15
公開日2023-01-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations.
Angew.Chem.Int.Ed.Engl., 62, 2023
5NL0
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BU of 5nl0 by Molmil
Crystal structure of a 197-bp palindromic 601L nucleosome in complex with linker histone H1
分子名称: DNA (197-MER), Histone H1.0-B, Histone H2A type 1, ...
著者Garcia-Saez, I, Petosa, C, Dimitrov, S.
登録日2017-04-03
公開日2017-05-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (5.4 Å)
主引用文献Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.
Mol. Cell, 66, 2017
6RWK
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BU of 6rwk by Molmil
MxiD N0 N1 and MxiG C-terminal domains of the Shigella type 3 secretion system
分子名称: Outer membrane protein MxiD, Protein MxiG
著者Kamprad, A, Lunelli, M.
登録日2019-06-05
公開日2020-02-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Cryo-EM structure of the Shigella type III needle complex.
Plos Pathog., 16, 2020
5ZOK
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Crystal structure of human SMAD1-MAN1 complex.
分子名称: Inner nuclear membrane protein Man1, Mothers against decapentaplegic homolog 1
著者Miyazono, K, Ito, T, Tanokura, M.
登録日2018-04-13
公開日2018-10-17
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural basis for receptor-regulated SMAD recognition by MAN1
Nucleic Acids Res., 46, 2018

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