PDB: 19129 件ウェブページステータス検索Chemie searchBIRD

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7JWU	Crystal structure of human ALDH1A1 bound to compound (R)-28 分子名称: 1-methyl-5-phenyl-6-{[(1R)-1-(pyridin-2-yl)ethyl]sulfanyl}-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Hurley, T.D, Buchman, C. 登録日 2020-08-26 公開日 2020-12-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. Eur.J.Med.Chem., 211, 2020
7JWT	Crystal structure of human ALDH1A1 bound to compound (R)-28 分子名称: 6-{[(1R)-1-(3-hydroxyphenyl)ethyl]sulfanyl}-1-methyl-5-phenyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, CHLORIDE ION, Retinal dehydrogenase 1, ... 著者 Hurley, T.D, Buchman, C. 登録日 2020-08-26 公開日 2020-12-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. Eur.J.Med.Chem., 211, 2020
3UN0	Crystal Structure of MDC1 FHA Domain 分子名称: Mediator of DNA damage checkpoint protein 1, SULFATE ION 著者 Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. 登録日 2011-11-15 公開日 2011-12-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator. Nucleic Acids Res., 40, 2012
3UOT	Crystal Structure of MDC1 FHA Domain in Complex with a Phosphorylated Peptide from the MDC1 N-terminus 分子名称: Mediator of DNA damage checkpoint protein 1 著者 Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. 登録日 2011-11-17 公開日 2011-12-28 最終更新日 2012-07-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator. Nucleic Acids Res., 40, 2012
3P06	Crystal structure of Tellina virus 1 VP4 protease in the form of an intra-molecular(cis)acyl-enzyme complex. 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ... 著者 Chung, I.Y.W, Paetzel, M. 登録日 2010-09-27 公開日 2011-02-02 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of a Viral Protease Intramolecular Acyl-enzyme Complex: INSIGHTS INTO cis-CLEAVAGE AT THE VP4/VP3 JUNCTION OF TELLINA BIRNAVIRUS. J.Biol.Chem., 286, 2011
3Q9D	Crystal Structure of Cpn0803 from C. pneumoniae. 分子名称: Protein CPn_0803/CP_1068/CPj0803/CpB0832 著者 Stone, C.B, Sugiman-Marangos, S.N, Junop, M.S, Mahony, J.B. 登録日 2011-01-07 公開日 2012-01-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Cpn0803 from C. pneumoniae. To be Published
2FPF	Crystal structure of the ib1 sh3 dimer at low resolution 分子名称: C-jun-amino-terminal kinase interacting protein 1 著者 Kristensen, O, Dar, I, Gajhede, M. 登録日 2006-01-16 公開日 2006-02-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A unique set of SH3-SH3 interactions controls IB1 homodimerization Embo J., 25, 2006
2FPD	Sad structure determination: crystal structure of the intrinsic dimerization sh3 domain of the ib1 scaffold protein 分子名称: C-jun-amino-terminal kinase interacting protein 1, SULFATE ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose 著者 Kristensen, O, Dar, I, Gajhede, M. 登録日 2006-01-16 公開日 2006-02-28 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 A unique set of SH3-SH3 interactions controls IB1 homodimerization Embo J., 25, 2006
2FPE	Conserved dimerization of the ib1 src-homology 3 domain 分子名称: C-jun-amino-terminal kinase interacting protein 1, HEXAETHYLENE GLYCOL, SULFATE ION, ... 著者 Guenat, S, Dar, I, Bonny, C, Kastrup, J.S, Gajhede, M, Kristensen, O. 登録日 2006-01-16 公開日 2006-02-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A unique set of SH3-SH3 interactions controls IB1 homodimerization Embo J., 25, 2006
3O2M	Crystal Structure of JNK1-alpha1 isoform complex with a biaryl tetrazol (A-82118) 分子名称: C-Jun-amino-terminal kinase-interacting protein 1, JIP1, 10MER PEPTIDE, ... 著者 Abad-Zapatero, C. 登録日 2010-07-22 公開日 2011-01-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases. Acs Chem.Biol., 6, 2011
3PTG	Design and Synthesis of a Novel, Orally Efficacious Tri-substituted Thiophene Based JNK Inhibitor 分子名称: C-Jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 10, N-[4-methyl-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide 著者 Bowers, S, Truong, A.P, Neitz, J, Neitzel, M, Probst, G.D, Hom, R.K, Konradi, A.W, Sham, H.L, Toth, G, Pan, H, Yao, N, Artis, D.R, Brigham, E.F, Quinn, K.P, Sauer, J, Powell, K, Ruslim, L, Bard, F, Yednock, T.A, Griswold-Prenner, I. 登録日 2010-12-02 公開日 2011-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor. Bioorg.Med.Chem.Lett., 21, 2011
2RHE	STRUCTURE OF A NOVEL BENCE-JONES PROTEIN (RHE) FRAGMENT AT 1.6 ANGSTROMS RESOLUTION 分子名称: BENCE-JONES PROTEIN RHE (LIGHT CHAIN) 著者 Fureyjunior, W, Wang, B.C, Yoo, C.S, Sax, M. 登録日 1983-06-13 公開日 1983-09-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of a novel Bence-Jones protein (Rhe) fragment at 1.6 A resolution. J.Mol.Biol., 167, 1983
5FV8	Structure of cJun-FosW coiled coil complex. 分子名称: CJUN, FOSW, GLYCEROL, ... 著者 Zaccai, N.R, Mason, J.M, Brady, R.L. 登録日 2016-02-03 公開日 2017-06-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Helix-Constrained Fos-Based Peptides Inhibit Oncogenic Activator Protein-1 and Cancer Cell Proliferation To be Published
1HIP	TWO-ANGSTROM CRYSTAL STRUCTURE OF OXIDIZED CHROMATIUM HIGH POTENTIAL IRON PROTEIN 分子名称: HIGH POTENTIAL IRON PROTEIN, IRON/SULFUR CLUSTER 著者 Carterjunior, C.W, Kraut, J, Freer, S.T, Xuong, N.-H, Alden, R.A, Bartsch, R.G. 登録日 1975-04-01 公開日 1976-11-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Two-Angstrom crystal structure of oxidized Chromatium high potential iron protein. J.Biol.Chem., 249, 1974
4ODB	Crystal structure of the T1L reovirus attachment protein sigma1 in complex with Junctional Adhesion Molecule-A 分子名称: Junctional adhesion molecule A, Outer capsid protein sigma-1 著者 Stettner, E, Stehle, T. 登録日 2014-01-10 公開日 2015-04-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The JAM-A binding site is conserved in reovirus sigma1: Structure of the T1L sigma1-JAM-A complex To be Published
7ZUO	Crystal Structure of Ljungan virus 4 2A2 protein, P212121 form 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... 著者 von Castelmur, E, Perrakis, A. 登録日 2022-05-12 公開日 2023-05-24 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structural Plasticity of Parechovirus H/NC-motif 2A proteins To Be Published
7ZUA	Crystal Structure of Ljungan virus 4 2A2 protein I222 crystal form 分子名称: ACETATE ION, Protein 2A 著者 von Castelmur, E, Perrakis, A. 登録日 2022-05-11 公開日 2023-05-24 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structural plasticity of Parechovirus family H-box 2A proteins To Be Published
8A2F	Crystal Structure of Ljunganvirus 1 2A protein 分子名称: 2A protein 著者 von Castelmur, E, Zhu, L, Wang, X, Fry, E, Ren, J, Perrakis, A, Stuart, D.I. 登録日 2022-06-03 公開日 2023-06-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structural plasticity of 2A proteins in the Parechovirus family To Be Published
4SDH	HIGH RESOLUTION CRYSTALLOGRAPHIC ANALYSIS OF A COOPERATIVE DIMERIC HEMOGLOBIN 分子名称: HEMOGLOBIN I (DEOXY), PROTOPORPHYRIN IX CONTAINING FE 著者 Royerjunior, W.E. 登録日 1993-06-23 公開日 1993-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 High-resolution crystallographic analysis of a co-operative dimeric hemoglobin. J.Mol.Biol., 235, 1994
2CNA	THE COVALENT AND THREE-DIMENSIONAL STRUCTURE OF CONCANAVALIN A, IV.ATOMIC COORDINATES,HYDROGEN BONDING,AND QUATERNARY STRUCTURE 分子名称: CALCIUM ION, CONCANAVALIN A, MANGANESE (II) ION 著者 Reekejunior, G.N, Becker, J.W, Edelman, G.M. 登録日 1975-04-01 公開日 1977-03-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The covalent and three-dimensional structure of concanavalin A. IV. Atomic coordinates, hydrogen bonding, and quaternary structure. J.Biol.Chem., 250, 1975
3SDH	HIGH RESOLUTION CRYSTALLOGRAPHIC ANALYSIS OF A COOPERATIVE DIMERIC HEMOGLOBIN 分子名称: CARBON MONOXIDE, HEMOGLOBIN I (CARBONMONOXY), PROTOPORPHYRIN IX CONTAINING FE 著者 Royerjunior, W.E. 登録日 1993-06-23 公開日 1993-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 High-resolution crystallographic analysis of a co-operative dimeric hemoglobin. J.Mol.Biol., 235, 1994
8CGO	Structure of human butyrylcholinesterase in complex with N-{[2-(benzyloxy)-3-methoxyphenyl]methyl}-N-[3-(2-fluorophenyl)propyl]cyclobutanamine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Brazzolotto, X, Pidany, F, Korabecny, J, Cahlikova, L, Nachon, F. 登録日 2023-02-06 公開日 2023-06-14 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Highly selective butyrylcholinesterase inhibitors related to Amaryllidaceae alkaloids - Design, synthesis, and biological evaluation. Eur.J.Med.Chem., 252, 2023
7YO9	Crystal structure of fusion protein of human TP53INP2 LIR and human GABARAP 分子名称: ISOPROPYL ALCOHOL, PHOSPHATE ION, Tumor protein p53-inducible nuclear protein 2,Gamma-aminobutyric acid receptor-associated protein 著者 Yamasaki, A, Noda, N.N. 登録日 2022-08-01 公開日 2022-11-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Development of new tools to study membrane-anchored mammalian Atg8 proteins. Autophagy, 19, 2023
5NUU	Torpedo californica acetylcholinesterase in complex with a chlorotacrine-tryptophan hybrid inhibitor 分子名称: (2~{S})-2-azanyl-~{N}-[6-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-3-(1~{H}-indol-3-yl)propanamide, Acetylcholinesterase, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Caliandro, R, Pesaresi, A, Lamba, D. 登録日 2017-05-02 公開日 2018-05-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease. Eur.J.Med.Chem., 168, 2019
1UKH	Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125 分子名称: 11-mer peptide from C-jun-amino-terminal kinase interacting protein 1, Mitogen-activated protein kinase 8 isoform 4 著者 Heo, Y.-S, Kim, Y.K, Sung, B.-J, Lee, H.S, Lee, J.I, Seo, C.I, Park, S.-Y, Kim, J.H, Hyun, Y.-L, Jeon, Y.H, Ro, S, Lee, T.G, Cho, J.M, Hwang, K.Y, Yang, C.-H. 登録日 2003-08-23 公開日 2004-08-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125 Embo J., 23, 2004

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