5Z2U
 
 | | ThDP-Mn2+ complex of R395A variant of EcMenD soaked with 2-ketoglutarate for 5 min | | 分子名称: | (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid, 1,2-ETHANEDIOL, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, ... | | 著者 | Qin, M.M, Guo, Z.H. | | 登録日 | 2018-01-04 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Two active site arginines are critical determinants of substrate binding and catalysis in MenD: a thiamine-dependent enzyme in menaquinone biosynthesis.
Biochem. J., 475, 2018
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3HWC
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6D24
 | | Trypanosoma cruzi Glucose-6-P Dehydrogenase in complex with G6P | | 分子名称: | 6-O-phosphono-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | | 著者 | Botti, H, Ortiz, C, Comini, M.A, Larrieux, N, Buschiazzo, A. | | 登録日 | 2018-04-12 | | 公開日 | 2018-05-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation.
J.Mol.Biol., 431, 2019
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3HL2
 | | The crystal structure of the human SepSecS-tRNASec complex | | 分子名称: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Monothiophosphate, O-phosphoseryl-tRNA(Sec) selenium transferase, ... | | 著者 | Palioura, S, Steitz, T.A, Soll, D, Simonovic, M. | | 登録日 | 2009-05-26 | | 公開日 | 2009-10-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation.
Science, 325, 2009
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5XKC
 | | Crystal structure of dibenzothiophene sulfone monooxygenase BdsA at 2.2 angstrome | | 分子名称: | Dibenzothiophene desulfurization enzyme A | | 著者 | Gu, L, Su, T, Liu, S, Su, J. | | 登録日 | 2017-05-07 | | 公開日 | 2018-05-09 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.209 Å) | | 主引用文献 | Structural and Biochemical Characterization of BdsA fromBacillus subtilisWU-S2B, a Key Enzyme in the "4S" Desulfurization Pathway.
Front Microbiol, 9, 2018
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6D23
 | | GLUCOSE-6-P DEHYDROGENASE (APO FORM) FROM TRYPANOSOMA CRUZI | | 分子名称: | CHLORIDE ION, GLYCEROL, Glucose-6-phosphate 1-dehydrogenase, ... | | 著者 | Botti, H, Ortiz, C, Comini, M.A, Larrieux, N, Buschiazzo, A. | | 登録日 | 2018-04-12 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation.
J.Mol.Biol., 431, 2019
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5Z2R
 | | ThDP-Mn2+ complex of R395K variant of EcMenD soaked with 2-ketoglutarate for 5 min | | 分子名称: | (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, FORMIC ACID, ... | | 著者 | Qin, M.M, Guo, Z.H. | | 登録日 | 2018-01-03 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Two active site arginines are critical determinants of substrate binding and catalysis in MenD: a thiamine-dependent enzyme in menaquinone biosynthesis.
Biochem. J., 475, 2018
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5Z2P
 | | ThDP-Mn2+ complex of R413K variant of EcMenD soaked with 2-ketoglutarate for 5 min | | 分子名称: | (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, FORMIC ACID, ... | | 著者 | Qin, M.M, Guo, Z.H. | | 登録日 | 2018-01-03 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Two active site arginines are critical determinants of substrate binding and catalysis in MenD: a thiamine-dependent enzyme in menaquinone biosynthesis.
Biochem. J., 475, 2018
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3HQN
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6D9Q
 | | The sulfate-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) | | 分子名称: | GLYCEROL, Hypoxanthine phosphoribosyltransferase, SULFATE ION | | 著者 | Satyshur, K.A, Dubiel, K, Anderson, B, Wolak, C, Keck, J.L. | | 登録日 | 2018-04-30 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.056 Å) | | 主引用文献 | Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction.
Elife, 8, 2019
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5ZBN
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6D42
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6D97
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3L8W
 | | Urate oxidase from aspergillus flavus complexed with xanthin | | 分子名称: | SODIUM ION, Uricase, XANTHINE, ... | | 著者 | Prange, T, Gabison, L, Colloc'h, N, Chiadmi, M. | | 登録日 | 2010-01-04 | | 公開日 | 2010-06-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Near-atomic resolution structures of urate oxidase complexed with its substrate and analogues: the protonation state of the ligand.
Acta Crystallogr.,Sect.D, 66, 2010
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5E6A
 | | Glucocorticoid receptor DNA binding domain - PLAU NF-kB response element complex | | 分子名称: | DNA (5'-D(*AP*TP*CP*AP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*TP*GP*AP*T)-3'), Glucocorticoid receptor, ... | | 著者 | Hudson, W.H, Rye, E.A, Herbst, A.G, Ortlund, E.A. | | 登録日 | 2015-10-09 | | 公開日 | 2017-02-08 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | | 主引用文献 | Cryptic glucocorticoid receptor-binding sites pervade genomic NF-kappa B response elements.
Nat Commun, 9, 2018
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6AYU
 | | Crystal structure of fructose-1,6-bisphosphatase T84S from Mycobacterium tuberculosis | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase class 2, GLYCEROL, ... | | 著者 | Abad-Zapatero, C, Wolf, N, Gutka, H.J, Movahedzadeh, F. | | 登録日 | 2017-09-08 | | 公開日 | 2018-03-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structures of the Mycobacterium tuberculosis GlpX protein (class II fructose-1,6-bisphosphatase): implications for the active oligomeric state, catalytic mechanism and citrate inhibition.
Acta Crystallogr D Struct Biol, 74, 2018
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5ZJM
 | | Crystal structure of N-acetylneuraminate lyase from Fusobacterium nucleatum | | 分子名称: | 1,2-ETHANEDIOL, N-acetylneuraminate lyase | | 著者 | Kumar, J.P, Rao, H, Nayak, V, Subramanian, R. | | 登録日 | 2018-03-21 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.323 Å) | | 主引用文献 | Crystal structures and kinetics of N-acetylneuraminate lyase from Fusobacterium nucleatum
Acta Crystallogr F Struct Biol Commun, 74, 2018
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5VF9
 | | Native human manganese superoxide dismutase | | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Azadmanesh, J, Trickel, S.R, Borgstahl, G.E.O. | | 登録日 | 2017-04-07 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Substrate-analog binding and electrostatic surfaces of human manganese superoxide dismutase.
J. Struct. Biol., 199, 2017
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6D7W
 | | Cryo-EM structure of the mitochondrial calcium uniporter from N. fischeri at 3.8 Angstrom resolution | | 分子名称: | CALCIUM ION, Mitochondrial calcium uniporter | | 著者 | Nguyen, N.X, Armache, J.-P, Cheng, Y, Bai, X.C. | | 登録日 | 2018-04-25 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structure of a fungal mitochondrial calcium uniporter.
Nature, 559, 2018
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5AL7
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5ZW8
 | | PigA with FAD and proline | | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Lee, C.-C, Ko, T.-P, Wang, A.H.J. | | 登録日 | 2018-05-14 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.689 Å) | | 主引用文献 | Crystal Structure of PigA: A Prolyl Thioester-Oxidizing Enzyme in Prodigiosin Biosynthesis.
Chembiochem, 20, 2019
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6DWJ
 | | SAMHD1 Bound to Vidarabine-TP in the Catalytic Pocket | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-9H-purin-6-amine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | | 著者 | Knecht, K.M, Buzovetsky, O, Schneider, C, Thomas, D, Srikanth, V, Kaderali, L, Tofoleanu, F, Reiss, K, Ferreiros, N, Geisslinger, G, Batista, V.S, Ji, X, Cinatl, J, Keppler, O.T, Xiong, Y. | | 登録日 | 2018-06-26 | | 公開日 | 2018-10-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5AOQ
 | | Structural basis of neurohormone perception by the receptor tyrosine kinase Torso | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PREPROPTTH, TORSO | | 著者 | Jenni, S, Goyal, Y, von Grotthuss, M, Shvartsman, S.Y, Klein, D.E. | | 登録日 | 2015-09-11 | | 公開日 | 2015-11-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Basis of Neurohormone Perception by the Receptor Tyrosine Kinase Torso.
Mol.Cell, 60, 2015
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6DD8
 | | Structure of mouse SYCP3, P21 form | | 分子名称: | Synaptonemal complex protein 3 | | 著者 | Rosenberg, S.C, Munoz, I.C, Uson, I, Corbett, K.D. | | 登録日 | 2018-05-09 | | 公開日 | 2018-08-01 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A conserved filamentous assembly underlies the structure of the meiotic chromosome axis.
Elife, 8, 2019
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6DT0
 | | Cryo-EM structure of a mitochondrial calcium uniporter | | 分子名称: | CALCIUM ION, Mitochondrial calcium uniporter | | 著者 | Yoo, J, Wu, M, Yin, Y, Herzik, M.A.J, Lander, G.C, Lee, S.-Y. | | 登録日 | 2018-06-14 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structure of a mitochondrial calcium uniporter.
Science, 361, 2018
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