5H5U
 
 | | Mechanistic insights into the alternative translation termination by ArfA and RF2 | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Ma, C, Kurita, D, Li, N, Chen, Y, Himeno, H, Gao, N. | | 登録日 | 2016-11-09 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Mechanistic insights into the alternative translation termination by ArfA and RF2
Nature, 541, 2017
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1K73
 | | Co-crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit | | 分子名称: | 23S RRNA, 5S RRNA, ANISOMYCIN, ... | | 著者 | Hansen, J, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A. | | 登録日 | 2001-10-18 | | 公開日 | 2003-07-22 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of
the Large Ribosomal Subunit
J.Mol.Biol., 330, 2003
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7W5Z
 | | Cryo-EM structure of Tetrahymena thermophila mitochondrial complex IV, composite dimer model | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-oxoglutarate/malate carrier protein, CARDIOLIPIN, ... | | 著者 | Zhou, L, Maldonado, M, Padavannil, A, Letts, J. | | 登録日 | 2021-11-30 | | 公開日 | 2022-04-06 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism.
Science, 376, 2022
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7QSO
 | | Bovine complex I in lipid nanodisc, State 3 (Slack) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Chung, I, Bridges, H.R, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
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5E8K
 | | Crystal structure of polyprenyl pyrophosphate synthase 2 from Arabidopsis thaliana | | 分子名称: | Geranylgeranyl pyrophosphate synthase 10, mitochondrial | | 著者 | Wang, C, Chen, Q, Fan, D, Li, J, Wang, G, Zhang, P. | | 登録日 | 2015-10-14 | | 公開日 | 2015-11-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.028 Å) | | 主引用文献 | Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants.
Mol Plant, 9, 2016
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6YWV
 | | The structure of the Atp25 bound assembly intermediate of the mitoribosome from Neurospora crassa | | 分子名称: | 23 S rRNA, 50S ribosomal protein L14, 50S ribosomal protein L17, ... | | 著者 | Amunts, A, Itoh, Y, Naschberger, A. | | 登録日 | 2020-04-30 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi.
Nat Commun, 11, 2020
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8DNV
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5JC9
 | | Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | | 著者 | Cocozaki, A, Ferguson, A. | | 登録日 | 2016-04-14 | | 公開日 | 2016-07-06 | | 最終更新日 | 2016-08-03 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
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7CPV
 | | Cryo-EM structure of 80S ribosome from mouse testis | | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | | 著者 | Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. | | 登録日 | 2020-08-08 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | A male germ-cell-specific ribosome controls male fertility.
Nature, 612, 2022
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5J3C
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8FKZ
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7R7A
 | | State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model | | 分子名称: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | | 著者 | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | | 登録日 | 2021-06-24 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
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7B93
 | | Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at 3.0 A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-5-[3-[4-(trifluoromethyloxy)phenyl]-1,2,4-oxadiazol-5-yl]pyridin-2-one, ... | | 著者 | Chung, I, Hirst, J. | | 登録日 | 2020-12-14 | | 公開日 | 2021-05-26 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Cork-in-bottle mechanism of inhibitor binding to mammalian complex I.
Sci Adv, 7, 2021
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6V39
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7NAC
 | | State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model | | 分子名称: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | | 著者 | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | | 登録日 | 2021-06-21 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
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4WRA
 | | Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site and with antibiotic paromomycin. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | | 登録日 | 2014-10-23 | | 公開日 | 2015-06-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
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7MPI
 | | Stm1 bound vacant 80S structure isolated from cbf5-D95A | | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | 著者 | Rai, J, Zhao, Y, Li, H. | | 登録日 | 2021-05-04 | | 公開日 | 2022-05-11 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations.
Structure, 30, 2022
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4WR6
 | | Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | | 登録日 | 2014-10-23 | | 公開日 | 2015-06-10 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
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8CQW
 | | Crystal structure of the Candida albicans 80S ribosome in complex with Hygromycin B | | 分子名称: | 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | | 著者 | Kolosova, O, Zgadzay, Y, Yusupov, M. | | 登録日 | 2023-03-07 | | 公開日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
To Be Published
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7JQM
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-002, mRNA, and deacylated P-site tRNA at 3.05A resolution | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M. | | 登録日 | 2020-08-11 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens.
J.Med.Chem., 63, 2020
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7S0S
 | | M. tuberculosis ribosomal RNA methyltransferase TlyA bound to M. smegmatis 50S ribosomal subunit | | 分子名称: | 16S/23S rRNA (Cytidine-2'-O)-methyltransferase TlyA, 23S rRNA, 50S ribosomal protein L10, ... | | 著者 | Laughlin, Z.T, Dunham, C.M, Conn, G.L. | | 登録日 | 2021-08-31 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | 50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA.
Proc.Natl.Acad.Sci.USA, 119, 2022
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4DZW
 | | Crystal Structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(cyclohexylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+ | | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... | | 著者 | Aripirala, S, Amzel, L.M, Gabelli, S.B. | | 登録日 | 2012-03-01 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
J.Med.Chem., 55, 2012
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7N8B
 | | Cycloheximide bound vacant 80S structure isolated from cbf5-D95A | | 分子名称: | 18S RIBOSOMAL RNA, 25S, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | | 著者 | Rai, J, Zhao, Y, Li, H. | | 登録日 | 2021-06-14 | | 公開日 | 2022-05-11 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations.
Structure, 30, 2022
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6SZS
 | | Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Muller, C, Beckert, B, Wilson, D.N. | | 登録日 | 2019-10-02 | | 公開日 | 2019-12-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis.
Nat Commun, 10, 2019
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5MDW
 | | Structure of ArfA(A18T) and RF2 bound to the 70S ribosome (pre-accommodated state) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2016-11-13 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Translational termination without a stop codon.
Science, 354, 2016
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