PDB: 2832 件ウェブページステータス検索Chemie searchBIRD

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5LZZ	Structure of the mammalian rescue complex with Pelota and Hbs1l (combined) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. 登録日 2016-10-02 公開日 2016-11-30 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
5LZY	Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA. 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. 登録日 2016-10-02 公開日 2016-11-30 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.99 Å) 主引用文献 Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
5L9T	Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... 著者 Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A. 登録日 2016-06-11 公開日 2016-10-26 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C. Cell, 165, 2016
6Q0K	Structure of a MAPK pathway complex 分子名称: 14-3-3 protein zeta/delta, Serine/threonine-protein kinase B-raf 著者 Park, E, Rawson, S, Jeon, H, Eck, M.J. 登録日 2019-08-01 公開日 2019-10-09 最終更新日 2020-04-22 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature, 575, 2019
7A5P	Human C Complex Spliceosome - Medium-resolution PERIPHERY 分子名称: Cell division cycle 5-like protein, Crooked neck-like protein 1, Eukaryotic initiation factor 4A-III, ... 著者 Bertram, K, Kastner, B. 登録日 2020-08-21 公開日 2020-10-14 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome. Mol.Cell, 80, 2020
8FKU	Human nucleolar pre-60S ribosomal subunit (State C2) 分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L10a, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.82 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
1N78	Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and glutamol-AMP. 分子名称: GLUTAMOL-AMP, Glutamyl-tRNA synthetase, MAGNESIUM ION, ... 著者 Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2002-11-13 公開日 2003-02-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding EMBO J., 22, 2003
8FKT	Human nucleolar pre-60S ribosomal subunit (State C1) 分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L10a, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.81 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
1N77	Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and ATP. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Glutamyl-tRNA synthetase, MAGNESIUM ION, ... 著者 Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2002-11-13 公開日 2003-02-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding EMBO J., 22, 2003
5AJ0	Cryo electron microscopy of actively translating human polysomes (POST state). 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T. 登録日 2015-02-19 公開日 2015-05-20 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural Snapshots of Actively Translating Human Ribosomes Cell(Cambridge,Mass.), 161, 2015
8FKZ	Human nucleolar pre-60S ribosomal subunit (State G) 分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L12, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FL7	Human nuclear pre-60S ribosomal subunit (State J2) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (2.55 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FL6	Human nuclear pre-60S ribosomal subunit (State J1) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.62 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FLD	Human nuclear pre-60S ribosomal subunit (State L1) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FLB	Human nuclear pre-60S ribosomal subunit (State K2) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (2.55 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
6FF7	human Bact spliceosome core structure 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... 著者 Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. 登録日 2018-01-03 公開日 2019-03-13 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
8FLA	Human nuclear pre-60S ribosomal subunit (State K1) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (2.63 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FLE	Human nuclear pre-60S ribosomal subunit (State L2) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.48 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
5D2D	Crystal structure of human 14-3-3 zeta in complex with CFTR R-domain peptide pS753-pS768 分子名称: 14-3-3 protein zeta/delta, CHLORIDE ION, Cystic fibrosis transmembrane conductance regulator, ... 著者 Stevers, L.M, Leysen, S.F.R, Ottmann, C. 登録日 2015-08-05 公開日 2016-03-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR. Proc.Natl.Acad.Sci.USA, 113, 2016
5D3F	Crystal structure of human 14-3-3 zeta in complex with CFTR R-domain peptide pS753-pS768 and stabilizer fusicoccin-A 分子名称: 14-3-3 protein zeta/delta, Cystic fibrosis transmembrane conductance regulator, FUSICOCCIN 著者 Stevers, L.M, Leysen, S.F.R, Ottmann, C. 登録日 2015-08-06 公開日 2016-03-16 最終更新日 2019-03-13 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR. Proc.Natl.Acad.Sci.USA, 113, 2016
6XA1	Structure of a drug-like compound stalled human translation termination complex 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J. 登録日 2020-06-03 公開日 2020-10-07 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Selective inhibition of human translation termination by a drug-like compound. Nat Commun, 11, 2020
8Y0U	dormant ribosome with STM1 分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S1-A, ... 著者 Du, M, Zeng, F. 登録日 2024-01-23 公開日 2024-02-07 実験手法 ELECTRON MICROSCOPY (3.59 Å) 主引用文献 dormant ribosome with STM1 To Be Published
5KPM	Glycogen Synthase Kinase 3 beta Complexed with BRD3731 分子名称: (4~{S})-3-(2,2-dimethylpropyl)-4,7,7-trimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta 著者 Lakshminarasimhan, D, White, A, Nadupalli, A, Suto, R.K. 登録日 2016-07-04 公開日 2018-03-14 最終更新日 2018-03-21 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med, 10, 2018
5KPL	Glycogen Synthase Kinase 3 beta Complexed with BRD0705 分子名称: (4~{S})-4-ethyl-7,7-dimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta 著者 Lakshminarasimhan, D, White, A, Nadupalli, A, Suto, R.K. 登録日 2016-07-04 公開日 2018-03-14 最終更新日 2018-03-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med, 10, 2018
7XNY	High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Cheng, J, Beckmann, R. 登録日 2022-04-30 公開日 2023-04-05 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia. Cancer Discov, 13, 2023

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