PDB: 37044 件ウェブページステータス検索Chemie searchBIRD

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4GL7	Structure of human placental aromatase complexed with designed inhibitor HDDG046 (compound 5) 分子名称: (6alpha,8alpha)-6-(pent-2-yn-1-yloxy)androsta-1,4-diene-3,17-dione, Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE 著者 Ghosh, D. 登録日 2012-08-13 公開日 2012-09-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Novel aromatase inhibitors by structure-guided design. J.Med.Chem., 55, 2012
1GB2	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-06-26 公開日 2000-07-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
1GB9	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-06-26 公開日 2000-07-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
4GLM	Crystal structure of the SH3 Domain of DNMBP protein [Homo sapiens] 分子名称: Dynamin-binding protein, UNKNOWN ATOM OR ION 著者 Dong, A, Guan, X, Huang, H, Tempel, W, Gu, J, Sidhu, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) 登録日 2012-08-14 公開日 2012-11-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the SH3 Domain of DNMBP protein [Homo sapiens] to be published
4GN5	OBody AM3L15 bound to hen egg-white lysozyme 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, GLYCEROL, ... 著者 Steemson, J.D, Liddament, M.T. 登録日 2012-08-16 公開日 2013-08-21 最終更新日 2014-02-12 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Tracking Molecular Recognition at the Atomic Level with a New Protein Scaffold Based on the OB-Fold. Plos One, 9, 2014
4GLY	Human urokinase-type plasminogen activator uPA in complex with the two-disulfide bridge peptide UK504 分子名称: BICYCLIC PEPTIDE INHIBITOR UK504, CHLORIDE ION, GLYCEROL, ... 著者 Buth, S.A, Leiman, P.G, Chen, S, Heinis, C. 登録日 2012-08-15 公開日 2013-05-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.518 Å) 主引用文献 Bicyclic Peptide Ligands Pulled out of Cysteine-Rich Peptide Libraries. J.Am.Chem.Soc., 135, 2013
1GDN	FUSARIUM OXYSPORUM TRYPSIN AT ATOMIC RESOLUTION 分子名称: GLY-ALA-LYS, GLYCEROL, SULFATE ION, ... 著者 Rypniewski, W.R, Oestergaard, P, Noerregaard-Madsen, M, Dauter, M, Wilson, K.S. 登録日 2000-09-28 公開日 2001-02-07 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (0.81 Å) 主引用文献 Fusarium oxysporum trypsin at atomic resolution at 100 and 283 K: a study of ligand binding. Acta Crystallogr.,Sect.D, 57, 2001
3QK3	Crystal structure of human beta-crystallin B3 分子名称: 1,2-ETHANEDIOL, Beta-crystallin B3, SULFATE ION 著者 Krojer, T, Gileadi, C, Cocking, R, Muniz, J, Pilka, E, Yue, W.W, Vollmar, M, Pike, A.C.W, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Kavanagh, K, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2011-01-31 公開日 2011-02-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献
1GF8	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-12-04 公開日 2000-12-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability. J.Biol.Chem., 277, 2002
4GN4	OBody AM2EP06 bound to hen egg-white lysozyme 分子名称: GLYCEROL, Lysozyme C, OBody AM2EP06 著者 Steemson, J.D, Liddament, M.T. 登録日 2012-08-16 公開日 2013-08-21 最終更新日 2014-02-12 実験手法 X-RAY DIFFRACTION (1.861 Å) 主引用文献 Tracking Molecular Recognition at the Atomic Level with a New Protein Scaffold Based on the OB-Fold. Plos One, 9, 2014
4GBQ	SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, 15 STRUCTURES 分子名称: GRB2, SOS-1 著者 Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L. 登録日 1996-12-23 公開日 1997-09-04 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts. J.Mol.Biol., 267, 1997
4GCR	STRUCTURE OF THE BOVINE EYE LENS PROTEIN GAMMA-B (GAMMA-II)-CRYSTALLIN AT 1.47 ANGSTROMS 分子名称: GAMMA-B CRYSTALLIN 著者 Slingsby, C, Najmudin, S, Nalini, V, Driessen, H.P.C, Blundell, T.L, Moss, D.S, Lindley, P. 登録日 1992-04-02 公開日 1993-10-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Structure of the bovine eye lens protein gammaB(gammaII)-crystallin at 1.47 A. Acta Crystallogr.,Sect.D, 49, 1993
1GI6	A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE 分子名称: 2-(2-HYDROXY-PHENYL)-1H-INDOLE-5-CARBOXAMIDINE, BETA-TRYPSIN, CALCIUM ION, ... 著者 Katz, B.A, Elrod, K, Luong, C, Rice, M, Mackman, R.L, Sprengeler, P.A, Spencer, J, Hatayte, J, Janc, J, Link, J, Litvak, J, Rai, R, Rice, K, Sideris, S, Verner, E, Young, W. 登録日 2001-01-22 公開日 2002-01-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site. J.Mol.Biol., 307, 2001
4GCH	STRUCTURE AND ACTIVITY OF TWO PHOTOREVERSIBLE CINNAMATES BOUND TO CHYMOTRYPSIN 分子名称: 3-(4-DIETHYLAMINO-2-HYDROXY-PHENYL)-2-METHYL-PROPIONIC ACID, GAMMA-CHYMOTRYPSIN A 著者 Stoddard, B.L, Ringe, D, Petsko, G.A. 登録日 1989-09-25 公開日 1990-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and activity of two photoreversible cinnamates bound to chymotrypsin. Biochemistry, 29, 1990
1GMC	THE X-RAY CRYSTAL STRUCTURE OF THE TETRAHEDRAL INTERMEDIATE OF GAMMA-CHYMOTRYPSIN IN HEXANE 分子名称: GAMMA-CHYMOTRYPSIN A, PRO GLY ALA TYR PEPTIDE 著者 Yennawar, N.H, Yennawar, H.P, Banerjee, S, Farber, G.K. 登録日 1993-08-20 公開日 1993-10-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 X-ray crystal structure of gamma-chymotrypsin in hexane. Biochemistry, 33, 1994
4ILZ	Structural and kinetic study of an internal substrate binding site of dehaloperoxidase-hemoglobin A from Amphitrite ornata 分子名称: 2,4,6-TRIBROMOPHENOL, Dehaloperoxidase A, ISOPROPYL ALCOHOL, ... 著者 de Serrano, V.S, Zhao, J, Zhao, J, Franzen, S. 登録日 2013-01-01 公開日 2013-03-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structural and Kinetic Study of an Internal Substrate Binding Site in Dehaloperoxidase-Hemoglobin A from Amphitrite ornata. Biochemistry, 52, 2013
3QI1	Design and synthesis of hydroxyethylamine (hea) BACE-1 inhibitors: prime side chromane-containing inhibitors 分子名称: Beta-secretase 1, N-[(2S,3R)-4-{[(2R,4S)-2-cyclopropyl-6-(2,2-dimethylpropyl)-3,4-dihydro-2H-chromen-4-yl]amino}-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]acetamide 著者 Yao, N. 登録日 2011-01-26 公開日 2012-03-28 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
1GAZ	Crystal Structure of Mutant Human Lysozyme Substituted at the Surface Positions 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-06-26 公開日 2000-07-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of amino acid residues at turns in the conformational stability and folding of human lysozyme. Biochemistry, 39, 2000
1GB5	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-06-26 公開日 2000-07-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
7Z39	Structure of Belumosudil bound to CK2alpha 分子名称: 2-[3-[4-(1~{H}-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-~{N}-propan-2-yl-ethanamide, ACETATE ION, Casein kinase II subunit alpha, ... 著者 Brear, P, Hyvonen, M. 登録日 2022-03-01 公開日 2022-10-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the Rho-associated coiled-coil kinase 2 inhibitor belumosudil bound to CK2 alpha. Acta Crystallogr.,Sect.F, 78, 2022
1GF0	BURIED POLAR MUTANT HUMAN LYSOZYME 分子名称: LYSOZYME, SODIUM ION 著者 Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-11-30 公開日 2001-04-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
4GPO	Oligomeic Turkey Beta1-Adrenergic G Protein-Coupled Receptor 分子名称: Beta-1 adrenergic receptor 著者 Huang, J.J, Chen, S, Zhang, J.J, Huang, X.Y. 登録日 2012-08-21 公開日 2013-02-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure of oligomeric beta-1-adrenergic G protein-coupled receptors in ligand-free basal state. Nat.Struct.Mol.Biol., 20, 2013
1GBD	ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID 分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION 著者 Mace, J.E, Agard, D.A. 登録日 1995-09-06 公開日 1996-01-29 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. J.Mol.Biol., 254, 1995
1GF6	BURIED POLAR MUTANT HUMAN LYSOZYME 分子名称: LYSOZYME, SODIUM ION 著者 Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-11-30 公開日 2001-04-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
1GFE	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-12-04 公開日 2000-12-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability. J.Biol.Chem., 277, 2002

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