PDB: 37044 件ウェブページステータス検索Chemie searchBIRD

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2XKR	Crystal Structure of Mycobacterium tuberculosis CYP142: A novel cholesterol oxidase 分子名称: PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 142, TETRAETHYLENE GLYCOL 著者 Driscoll, M, McLean, K.J, Levy, C.W, Lafite, P, Mast, N, Pikuleva, I.A, Rigby, S.E.J, Leys, D, Munro, A.W. 登録日 2010-07-12 公開日 2010-09-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Structural and Biochemical Characterization of Mycobacterium Tuberculosis Cyp142: Evidence for Multiple Cholesterol 27-Hydroxylase Activities in a Human Pathogen. J.Biol.Chem., 285, 2010
4L36	Crystal structure of the cytochrome P450 enzyme TxtE 分子名称: HEME B/C, IMIDAZOLE, Putative P450-like protein 著者 Yu, F, Li, M.J, Xu, C.Y, Wang, Z.J, Zhou, H, Yang, M, Chen, Y.X, Tang, L, He, J.H. 登録日 2013-06-05 公開日 2013-12-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.104 Å) 主引用文献 Structural Insights into the Mechanism for Recognizing Substrate of the Cytochrome P450 Enzyme TxtE. Plos One, 8, 2013
1GF7	BURIED POLAR MUTANT HUMAN LYSOZYME 分子名称: LYSOZYME, SODIUM ION 著者 Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-11-30 公開日 2001-04-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contribution of polar groups in the interior of a protein to the conformational stability Biochemistry, 40, 2001
4L4A	Structure of L358A/K178G mutant of P450cam bound to camphor 分子名称: CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... 著者 Batabyal, D, Li, H, Poulos, T.L. 登録日 2013-06-07 公開日 2013-07-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.103 Å) 主引用文献 Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1. Biochemistry, 52, 2013
4L54	Structure of cytochrome P450 OleT, ligand-free 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Terminal olefin-forming fatty acid decarboxylase 著者 Leys, D. 登録日 2013-06-10 公開日 2013-11-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE (CYP152L1) from the Jeotgalicoccus sp. 8456 Bacterium. J.Biol.Chem., 289, 2014
3Q4B	Clinically Useful Alkyl Amine Renin Inhibitors 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Renin, ... 著者 Wu, Z, McKeever, B.M. 登録日 2010-12-23 公開日 2011-11-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility. ACS Med Chem Lett, 2, 2011
7YNU	Crystal structure of Hen Egg white LYSOZYME introduced with O-(2-nitrobenzyl)-L-tyrosine 分子名称: ACETATE ION, CHLORIDE ION, Lysozyme C, ... 著者 Hosaka, T, Shirouzu, M. 登録日 2022-08-01 公開日 2022-09-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Crystal Structure of an Archaeal Tyrosyl-tRNA Synthetase Bound to Photocaged L-Tyrosine and Its Potential Application to Time-Resolved X-ray Crystallography. Int J Mol Sci, 23, 2022
2XMF	Myosin 1e SH3 分子名称: MYOSIN 1E SH3, OCTANE 1,8-DIAMINE 著者 Edwards, T, Allsop, G, Peckham, M. 登録日 2010-07-27 公開日 2011-08-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Myosin 1E SH3 To be Published
7YNV	Crystal structure of photolysed Hen Egg white LYSOZYME introduced with O-(2-nitrobenzyl)-L-tyrosine 分子名称: ACETATE ION, CHLORIDE ION, Lysozyme C, ... 著者 Hosaka, T, Shirouzu, M. 登録日 2022-08-01 公開日 2022-09-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Crystal Structure of an Archaeal Tyrosyl-tRNA Synthetase Bound to Photocaged L-Tyrosine and Its Potential Application to Time-Resolved X-ray Crystallography. Int J Mol Sci, 23, 2022
3PI8	Site-specific Glycosylation of Hemoglobin Utilizing Oxime Ligation Chemistry as a Viable Alternative to PEGylation 分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... 著者 Bhatt, V.S, Styslinger, T.J, Zhang, N, Wang, P.G, Palmer, A.F. 登録日 2010-11-05 公開日 2010-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献
4L85	Crystal structure of receiver domain of KdpE D52A mutant from E. coli 分子名称: IODIDE ION, KDP operon transcriptional regulatory protein KdpE 著者 Kumar, S, Yernool, D.A. 登録日 2013-06-15 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.202 Å) 主引用文献 An asymmetric heterodomain interface stabilizes a response regulator-DNA complex. Nat Commun, 5, 2014
4GJ5	Crystal structure of renin in complex with NVP-AMQ838 (compound 5) 分子名称: (3R,4R)-3-(naphthalen-2-ylmethoxy)-4-phenylpiperidine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin 著者 Ostermann, N, Zink, F, Kroemer, M. 登録日 2012-08-09 公開日 2013-03-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Discovery of Novel Potent trans-3,4-Disubstituted Pyrrolidine Inhibitors of the Human Aspartic Protease Renin from in Silico Three-Dimensional (3D) Pharmacophore Searches. J.Med.Chem., 56, 2013
3PPE	Crystal structure of chicken VE-cadherin EC1-2 分子名称: CALCIUM ION, Vascular endothelial cadherin 著者 Brasch, J, Harrison, O.J, Ahlsen, G, Carnally, S.M, Henderson, R.M, Honig, B, Shapiro, L.S. 登録日 2010-11-24 公開日 2011-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and binding mechanism of vascular endothelial cadherin: a divergent classical cadherin. J.Mol.Biol., 408, 2011
1GB7	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-06-26 公開日 2000-07-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
1GBX	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-06-26 公開日 2000-07-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
4GLD	Crystal Structure of the complex of type II phospholipase A2 with a designed peptide inhibitor Phe - Leu - Ala - Tyr - Lys at 1.69 A resolution 分子名称: ACETATE ION, FLAYK, Phospholipase A2 VRV-PL-VIIIa, ... 著者 Shukla, P.K, Sinha, M, Dey, S, Kaur, P, Sharma, S, Singh, T.P. 登録日 2012-08-14 公開日 2012-08-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Crystal Structure of the complex of type II phospholipase A2 with a designed peptide inhibitor Phe - Leu - Ala - Tyr - Lys at 1.69 A resolution To be Published
3PM0	Structural Characterization of the Complex between Alpha-Naphthoflavone and Human Cytochrome P450 1B1 (CYP1B1) 分子名称: 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE, Cytochrome P450 1B1, PROTOPORPHYRIN IX CONTAINING FE 著者 Wang, A, Stout, C.D, Johnson, E.F. 登録日 2010-11-15 公開日 2010-12-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Characterization of the Complex between {alpha}-Naphthoflavone and Human Cytochrome P450 1B1. J.Biol.Chem., 286, 2011
3PTL	Crystal structure of proteinase K inhibited by a lactoferrin nonapeptide, Lys-Gly-Glu-Ala-Asp-Ala-Leu-Ser-Leu-Asp at 1.3 A resolution. 分子名称: 10-mer peptide from Lactoferrin, Proteinase K 著者 Shukla, P.K, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. 登録日 2010-12-03 公開日 2010-12-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of proteinase K inhibited by a lactoferrin nonapeptide, Lys-Gly-Glu-Ala-Asp-Ala-Leu-Ser-Leu-Asp at 1.3 A resolution. TO BE PUBLISHED
1FY5	Fusarium oxysporum trypsin at atomic resolution 分子名称: GLY-ALA-LYS, GLYCEROL, SULFATE ION, ... 著者 Rypniewski, W.R, Oestergaard, P, Noerregaard-Madsen, M, Dauter, M, Wilson, K.S. 登録日 2000-09-28 公開日 2001-02-07 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (0.81 Å) 主引用文献 Fusarium oxysporum trypsin at atomic resolution at 100 and 283 K: a study of ligand binding. Acta Crystallogr.,Sect.D, 57, 2001
2YBJ	Nitrate X-ray induced reduction on HEWL crystals (12.31 MGy) 分子名称: LYSOZYME C, NITRITE ION 著者 De la Mora, E, Carmichael, I, Garman, E.F. 登録日 2011-03-08 公開日 2011-07-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Effective Scavenging at Cryotemperatures: Further Increasing the Dose Tolerance of Protein Crystals. J.Synchrotron.Radiat., 18, 2011
4GJ8	Crystal structure of renin in complex with PKF909-724 (compound 3) 分子名称: (2R)-1-(pyrrolidin-1-yl)-3-(9H-thioxanthen-9-yl)propan-2-ol, (2S)-1-(pyrrolidin-1-yl)-3-(9H-thioxanthen-9-yl)propan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ostermann, N, Zink, F, Kroemer, M. 登録日 2012-08-09 公開日 2013-02-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore. J.Med.Chem., 56, 2013
4GJ6	Crystal structure of renin in complex with NVP-AYZ832 (compound 6a) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-{[(3S,4S)-4-benzylpyrrolidin-3-yl]methyl}-4-chloro-N-phenylaniline, Renin, ... 著者 Ostermann, N, Zink, F, Kroemer, M. 登録日 2012-08-09 公開日 2013-03-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 The Discovery of Novel Potent trans-3,4-Disubstituted Pyrrolidine Inhibitors of the Human Aspartic Protease Renin from in Silico Three-Dimensional (3D) Pharmacophore Searches. J.Med.Chem., 56, 2013
4GJD	Crystal structure of renin in complex with NVP-BGQ311 (compound 12) 分子名称: (3S,5R)-N-{[9-(4-methoxybutyl)-9H-xanthen-9-yl]methyl}-5-{[(4-methylphenyl)sulfonyl]amino}piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, ... 著者 Ostermann, N, Zink, F, Kroemer, M. 登録日 2012-08-09 公開日 2013-02-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore. J.Med.Chem., 56, 2013
3PWR	HIV-1 Protease Mutant L76V complexed with Saquinavir 分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, CHLORIDE ION, GLYCEROL, ... 著者 Zhang, Y, Weber, I.T. 登録日 2010-12-08 公開日 2011-04-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 The L76V Drug Resistance Mutation Decreases the Dimer Stability and Rate of Autoprocessing of HIV-1 Protease by Reducing Internal Hydrophobic Contacts. Biochemistry, 50, 2011
3PWW	Endothiapepsin in complex with saquinavir 分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, Endothiapepsin, GLYCEROL 著者 Koester, H, Heine, A, Klebe, G. 登録日 2010-12-09 公開日 2011-12-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Experimental and computational active site mapping as a starting point to fragment-based lead discovery. Chemmedchem, 7, 2012

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