2XKR

Crystal Structure of Mycobacterium tuberculosis CYP142: A novel cholesterol oxidase

Summary for 2XKR

Entry DOI	10.2210/pdb2xkr/pdb
Descriptor	PUTATIVE CYTOCHROME P450 142, PROTOPORPHYRIN IX CONTAINING FE, TETRAETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	oxidoreductase
Biological source	MYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains	1
Total formula weight	45256.10
Authors	Driscoll, M.,McLean, K.J.,Levy, C.W.,Lafite, P.,Mast, N.,Pikuleva, I.A.,Rigby, S.E.J.,Leys, D.,Munro, A.W. (deposition date: 2010-07-12, release date: 2010-09-29, Last modification date: 2023-12-20)
Primary citation	Driscoll, M.D.,Mclean, K.J.,Levy, C.W.,Mast, N.,Pikuleva, I.A.,Lafite, P.,Rigby, S.E.J.,Leys, D.,Munro, A.W. Structural and Biochemical Characterization of Mycobacterium Tuberculosis Cyp142: Evidence for Multiple Cholesterol 27-Hydroxylase Activities in a Human Pathogen. J.Biol.Chem., 285:38270-, 2010 Cited by PubMed: 20889498 DOI: 10.1074/JBC.M110.164293 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.601 Å)

Structure validation