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3KMG
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BU of 3kmg by Molmil
The X-ray Crystal Structure of PPAR-gamma in Complex with an Indole Derivative Modulator, GSK538, and an SRC-1 Peptide
分子名称: 4'-[(2,3-dimethyl-5-{[(1S)-1-phenylpropyl]carbamoyl}-1H-indol-1-yl)methyl]biphenyl-2-carboxylic acid, Peroxisome proliferator-activated receptor gamma, Steroid Receptor Coactivator-1
著者Gampe, R.
登録日2009-11-10
公開日2010-01-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Synthesis and biological activities of novel indole derivatives as potent and selective PPAR-gamma modulators
TO BE PUBLISHED
1YXA
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Serpina3n, a murine orthologue of human antichymotrypsin
分子名称: serine (or cysteine) proteinase inhibitor, clade A, member 3N
著者Horvath, A.J, Irving, J.A, Law, R.H, Rossjohn, J, Bottomley, S.P, Quinsey, N.S, Pike, R.N, Coughlin, P.B, Whisstock, J.C.
登録日2005-02-20
公開日2005-09-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins.
J.Biol.Chem., 280, 2005
1Z6O
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Crystal Structure of Trichoplusia ni secreted ferritin
分子名称: CALCIUM ION, FE (III) ION, Ferritin heavy chain, ...
著者Hamburger, A.E, West Jr, A.P, Hamburger, Z.A, Hamburger, P, Bjorkman, P.J.
登録日2005-03-22
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of a secreted insect ferritin reveals a symmetrical arrangement of heavy and light chains.
J.Mol.Biol., 349, 2005
6ZHH
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BU of 6zhh by Molmil
Ca2+-ATPase from Listeria Monocytogenes with G4 insertion.
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, BERYLLIUM TRIFLUORIDE ION, Calcium-transporting ATPase, ...
著者Basse Hansen, S, Dyla, M, Neumann, C, Quistgaard, E.M.H, Lauwring Andersen, J, Kjaergaard, M, Nissen, P.
登録日2020-06-23
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Crystal Structure of the Ca 2+ -ATPase 1 from Listeria monocytogenes reveals a Pump Primed for Dephosphorylation.
J.Mol.Biol., 433, 2021
1ZF3
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BU of 1zf3 by Molmil
ATC Four-stranded DNA Holliday Junction
分子名称: 5'-D(*CP*CP*GP*AP*TP*AP*TP*CP*GP*G)-3', CALCIUM ION
著者Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S.
登録日2005-04-19
公開日2005-05-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献How sequence defines structure: a crystallographic map of DNA structure and conformation.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1ZFH
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BU of 1zfh by Molmil
TTA Duplex B-DNA
分子名称: 5'-D(*CP*CP*TP*AP*AP*TP*TP*AP*GP*G)-3'
著者Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S.
登録日2005-04-20
公開日2005-05-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献How sequence defines structure: a crystallographic map of DNA structure and conformation.
Proc.Natl.Acad.Sci.Usa, 102, 2005
6Z0Z
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BU of 6z0z by Molmil
Human wtSTING in complex with 3',3'-c-(2'FdAMP-2'FdAMP)
分子名称: 2'-fluoro-,3',3'-c-di-AMP, Stimulator of interferon protein
著者Boura, E, Smola, M.
登録日2020-05-11
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
Angew.Chem.Int.Ed.Engl., 60, 2021
1QYE
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BU of 1qye by Molmil
Crystal Structure of the N-domain of the ER Hsp90 chaperone GRP94 in complex with 2-chlorodideoxyadenosine
分子名称: 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, 2-CHLORODIDEOXYADENOSINE, Endoplasmin
著者Soldano, K.L, Jivan, A, Nicchitta, C.V, Gewirth, D.T.
登録日2003-09-10
公開日2003-11-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the N-terminal Domain of GRP94. Basis for Ligand Specificity and Regulation
J.Biol.Chem., 278, 2003
1QZ1
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BU of 1qz1 by Molmil
Crystal Structure of the Ig 1-2-3 fragment of NCAM
分子名称: Neural cell adhesion molecule 1, 140 kDa isoform
著者Soroka, V, Kolkova, K, Kastrup, J.S, Diederichs, K, Breed, J, Kiselyov, V.V, Poulsen, F.M, Larsen, I.K, Welte, W, Berezin, V, Bock, E, Kasper, C.
登録日2003-09-15
公開日2003-11-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and interactions of NCAM Ig1-2-3 suggest a novel zipper mechanism for homophilic adhesion
Structure, 11, 2003
3KX5
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BU of 3kx5 by Molmil
Crystal structure of Bacillus megaterium BM3 heme domain mutant F261E
分子名称: Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Girvan, H.M, Levy, C.W, Leys, D, Munro, A.W.
登録日2009-12-02
公開日2010-05-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.686 Å)
主引用文献Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.
Biochem.J., 427, 2010
3KN1
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Crystal Structure of Golgi Phosphoprotein 3 N-term Truncation Variant
分子名称: Golgi phosphoprotein 3, SULFATE ION
著者Schmitz, K.R, Bessman, N.J, Setty, T.G, Ferguson, K.M.
登録日2009-11-11
公開日2009-12-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking.
J.Cell Biol., 187, 2009
3KDR
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BU of 3kdr by Molmil
The Crystal Structure of a HK97 Family Phage Portal Protein from Corynebacterium diphtheriae to 2.9A
分子名称: GLYCEROL, HK97 Family Phage Portal Protein, PHOSPHATE ION, ...
著者Nocek, B, Stein, A.J, Mulligan, R, Duggan, E, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2009-10-23
公開日2009-12-29
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Crystal Structure of a HK97 Family Phage Portal Protein from Corynebacterium diphtheriae to 2.9A
To be Published
1ZE1
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BU of 1ze1 by Molmil
Conformational Change of Pseudouridine 55 Synthase upon Its Association with RNA Substrate
分子名称: MAGNESIUM ION, tRNA pseudouridine synthase B
著者Phannachet, K, Huang, R.H.
登録日2005-04-16
公開日2005-04-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Conformational change of pseudouridine 55 synthase upon its association with RNA substrate
Nucleic Acids Res., 32, 2004
1Z0M
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BU of 1z0m by Molmil
the glycogen-binding domain of the AMP-activated protein kinase beta1 subunit
分子名称: 5'-AMP-activated protein kinase, beta-1 subunit, Cycloheptakis-(1-4)-(alpha-D-glucopyranose)
著者Polekhina, G, Gupta, A, van Denderen, B.J, Feil, S.C, Kemp, B.E, Stapleton, D, Parker, M.W.
登録日2005-03-02
公開日2005-10-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structural Basis for Glycogen Recognition by AMP-Activated Protein Kinase.
Structure, 13, 2005
1ZF7
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GAC Duplex B-DNA
分子名称: 5'-D(*CP*CP*GP*TP*CP*GP*AP*CP*GP*G)-3', CALCIUM ION, SODIUM ION
著者Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S.
登録日2005-04-20
公開日2005-05-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献How sequence defines structure: a crystallographic map of DNA structure and conformation.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1Q6O
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Structure of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-gulonaet 6-phosphate
分子名称: 3-keto-L-gulonate 6-phosphate decarboxylase, L-GULURONIC ACID 6-PHOSPHATE, MAGNESIUM ION
著者Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I.
登録日2003-08-13
公開日2003-10-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.202 Å)
主引用文献Structural Evidence for a 1,2-Enediolate Intermediate in the Reaction Catalyzed by 3-Keto-l-Gulonate 6-Phosphate Decarboxylase, a Member of the Orotidine 5'-Monophosphate Decarboxylase Suprafamily
Biochemistry, 42, 2003
1Q82
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BU of 1q82 by Molmil
Crystal Structure of CC-Puromycin bound to the A-site of the 50S ribosomal subunit
分子名称: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
著者Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2003-08-20
公開日2003-10-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Structural Insights Into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
6ZC7
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BU of 6zc7 by Molmil
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
分子名称: 5-bromanyl-2-[(phenylmethyl)sulfonylamino]benzoic acid, Dishevelled, dsh homolog 3 (Drosophila), ...
著者Roske, Y, Heinemann, U, Oschkinat, H.
登録日2020-06-09
公開日2021-06-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
J.Magn.Reson., 2021
1ZM2
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BU of 1zm2 by Molmil
Structure of ADP-ribosylated eEF2 in complex with catalytic fragment of ETA
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Exotoxin A
著者Joergensen, R, Merrill, A.R, Yates, S.P, Marquez, V.E, Schwan, A.L, Boesen, T, Andersen, G.R.
登録日2005-05-10
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry.
Nature, 436, 2005
6ZBR
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BU of 6zbr by Molmil
VEGF-A 13:107 crystallized with 4C bicyclic peptide
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Chains: P, PHOSPHATE ION, ...
著者Gaucher, J.-F, Broussy, S, Reille-Seroussi, M.
登録日2020-06-09
公開日2021-06-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands.
Chemistry, 2022
3KXX
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BU of 3kxx by Molmil
Structure of the mutant Fibroblast Growth Factor receptor 1
分子名称: Basic fibroblast growth factor receptor 1
著者Bae, J.H, Boggon, T.J, Tome, F, Mandiyan, V, Lax, I, Schlessinger, J.
登録日2009-12-04
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells.
Proc.Natl.Acad.Sci.USA, 107, 2010
1ZF9
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GGG Duplex A-DNA
分子名称: 5'-D(*CP*CP*CP*CP*CP*GP*GP*GP*GP*G)-3', SODIUM ION
著者Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S.
登録日2005-04-20
公開日2005-05-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献How sequence defines structure: a crystallographic map of DNA structure and conformation.
Proc.Natl.Acad.Sci.Usa, 102, 2005
6ZCD
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VEGF-A 13:107 crystallized with 1C bicyclic peptide
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Derived from V114 peptide, PHOSPHATE ION, ...
著者Gaucher, J.-F, Broussy, S, Reille-Seroussi, M.
登録日2020-06-10
公開日2021-06-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands.
Chemistry, 2022
1ZO9
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Crystal Structure Of The Wild Type Heme Domain Of P450BM-3 with N-palmitoylmethionine
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450:NADPH-P450 reductase, GLYCEROL, ...
著者Hegda, A, Chen, B, Tomchick, D.R, Bondlela, M, Haines, D.C, Schaffer, N, Machius, M, Graham, S.E, Peterson, J.A.
登録日2005-05-12
公開日2006-08-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Interactions of substrates at the surface of P450s can greatly enhance substrate potency.
Biochemistry, 46, 2007
6ZGO
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Thrombin in complex with D-Phe-Pro-2-chlorofuran derivative (13l)
分子名称: (2~{S})-1-[(2~{R})-2-azanyl-3-phenyl-propanoyl]-~{N}-[(5-chloranylfuran-2-yl)methyl]pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ...
著者Sandner, A, Heine, A, Klebe, G.
登録日2020-06-19
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Thrombin in complex with D-Phe-Pro-2-chlorofuran derivative (13l)
To be published

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