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1VYM
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NATIVE HUMAN PCNA
分子名称: PROLIFERATING CELL NUCLEAR ANTIGEN
著者Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M.
登録日2004-05-03
公開日2005-01-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design
Proc.Natl.Acad.Sci.USA, 102, 2005
1VYJ
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Structural and biochemical studies of human PCNA complexes provide the basis for association with CDK/cyclin and rationale for inhibitor design
分子名称: PROLIFERATING CELL NUCLEAR ANTIGEN, SMALL PEPTIDE SAVLQKKITDYFHPKK
著者Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M.D.
登録日2004-04-30
公開日2005-01-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design
Proc.Natl.Acad.Sci.USA, 102, 2005
1W60
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NATIVE HUMAN PCNA
分子名称: PROLIFERATING CELL NUCLEAR ANTIGEN
著者Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M.
登録日2004-08-11
公開日2005-01-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design
Proc.Natl.Acad.Sci.USA, 102, 2005
5LAP
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BU of 5lap by Molmil
p53 cancer mutant Y220C with Cys182 alkylation
分子名称: 5-chloranylpyrimidine-4-carboxylic acid, Cellular tumor antigen p53, ZINC ION
著者Joerger, A.C, Bauer, M.R, Fersht, A.R.
登録日2016-06-14
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells.
Proc.Natl.Acad.Sci.USA, 113, 2016
4O8B
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Crystal structure of transcriptional regulator BswR
分子名称: Uncharacterized protein
著者Ye, F.Z, Wang, C, Kumar, V, Zhang, L.H, Gao, Y.G.
登録日2013-12-26
公開日2014-02-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA rsmZ.
Nucleic Acids Res., 42, 2014
1VZ0
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Chromosome segregation protein Spo0J from Thermus thermophilus
分子名称: COBALT (II) ION, Chromosome-partitioning protein Spo0J, MAGNESIUM ION
著者Leonard, T.A, Butler, P.J.G, Lowe, J.
登録日2004-05-12
公開日2004-07-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of the chromosome segregation protein Spo0J from Thermus thermophilus.
Mol. Microbiol., 53, 2004
8GYZ
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Crystal structure of transcription factor TGA7 from Arabidopsis
分子名称: PALMITIC ACID, Transcription factor TGA7
著者Shi, X.Q, Che, Z, Ming, Z.H.
登録日2022-09-24
公開日2022-11-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Crystal structure of transcription factor TGA7 from Arabidopsis.
Biochem.Biophys.Res.Commun., 637, 2022
6RBL
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TETR(D) E147A MUTANT IN COMPLEX WITH DOXYCYCLINE AND MAGNESIUM
分子名称: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
著者Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
登録日2019-04-10
公開日2019-08-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
2XPV
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TetR(D) in complex with minocycline and magnesium.
分子名称: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
著者Dalm, D, Proft, J, Palm, G.J, Hinrichs, W.
登録日2010-08-30
公開日2011-09-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Tetr(D) in Complex with Minocycline.
To be Published
6RBM
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TETR(D) E147A MUTANT IN COMPLEX WITH MINOCYCLINE AND MAGNESIUM
分子名称: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
著者Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
登録日2019-04-11
公開日2019-08-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
6RCR
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BU of 6rcr by Molmil
TETR(D) H100A MUTANT IN COMPLEX WITH DOXYCYCLINE AND MAGNESIUM
分子名称: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
著者Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
登録日2019-04-11
公開日2019-08-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
6X67
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Cryo-EM structure of piggyBac transposase strand transfer complex (STC)
分子名称: CALCIUM ION, DNA (37-MER), DNA (47-MER), ...
著者Chen, Q, Hickman, A.B, Dyda, F.
登録日2020-05-27
公開日2020-07-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural basis of seamless excision and specific targeting by piggyBac transposase
Nat Commun, 11, 2020
3LA7
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Crystal structure of NtcA in apo-form
分子名称: Global nitrogen regulator, octyl beta-D-glucopyranoside
著者Zhao, M.X, Jiang, Y.L, He, Y.X, Chen, Y.F, Teng, Y.B, Zhang, C.C, Chen, Y.X, Zhou, C.Z.
登録日2010-01-06
公開日2010-09-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the allosteric control of the global transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate.
Proc.Natl.Acad.Sci.USA, 107, 2010
4F8D
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Crystal Structure of an R46A mutant of the Restriction-Modification Controller Protein C.Esp1396I (Monoclinic Form)
分子名称: Regulatory protein, SODIUM ION, SULFATE ION
著者Martin, R.N.A, McGeehan, J.E, Kneale, G.G.
登録日2012-05-17
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I.
Plos One, 9, 2014
6KW5
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The ClassC RSC-Nucleosome Complex
分子名称: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ...
著者Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C.
登録日2019-09-06
公開日2020-09-09
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (10.13 Å)
主引用文献Structure of the RSC complex bound to the nucleosome
To Be Published
1HME
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BU of 1hme by Molmil
STRUCTURE OF THE HMG BOX MOTIF IN THE B-DOMAIN OF HMG1
分子名称: HIGH MOBILITY GROUP PROTEIN FRAGMENT-B
著者Weir, H.M, Kraulis, P.J, Hill, C.S, Raine, A.R.C, Laue, E.D, Thomas, J.O.
登録日1994-02-10
公開日1994-05-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the HMG box motif in the B-domain of HMG1.
EMBO J., 12, 1993
6WWA
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Crystal structure of human SHLD2-SHLD3-REV7 complex
分子名称: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2,Shieldin complex subunit 3 chimera
著者Xie, W, Patel, D.J.
登録日2020-05-08
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
6WW9
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Crystal structure of human REV7(R124A)-SHLD3(35-58) complex
分子名称: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 3
著者Xie, W, Patel, D.J.
登録日2020-05-08
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
1WJ0
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Solution Structure of the DNA-Binding Domain of Squamosa Promoter Binding Protein-Like 12 Lacking the Second Zinc-Binding Site
分子名称: ZINC ION, squamosa promoter-binding protein-like 12
著者Yamasaki, K, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-28
公開日2004-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the SBP Domain That Lacks the Second Zinc-Binding Site
To be Published
1HNV
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STRUCTURE OF HIV-1 RT(SLASH)TIBO R 86183 COMPLEX REVEALS SIMILARITY IN THE BINDING OF DIVERSE NONNUCLEOSIDE INHIBITORS
分子名称: 5-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66)
著者Das, K, Ding, J, Arnold, E.
登録日1995-03-30
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors.
Nat.Struct.Biol., 2, 1995
5ECG
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BU of 5ecg by Molmil
Crystal structure of the BRCT domains of 53BP1 in complex with p53 and H2AX-pSer139 (gammaH2AX)
分子名称: Cellular tumor antigen p53, SEP-GLN-GLU-TYR, Tumor suppressor p53-binding protein 1, ...
著者Day, M, Oliver, A.W, Pearl, L.H.
登録日2015-10-20
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献ATM Localization and Heterochromatin Repair Depend on Direct Interaction of the 53BP1-BRCT2 Domain with gamma H2AX.
Cell Rep, 13, 2015
1IC8
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HEPATOCYTE NUCLEAR FACTOR 1A BOUND TO DNA : MODY3 GENE PRODUCT
分子名称: 5'-D(*CP*TP*TP*GP*GP*TP*TP*AP*AP*TP*AP*AP*TP*TP*CP*AP*CP*CP*AP*GP*A)-3', 5'-D(*TP*CP*TP*GP*GP*TP*GP*AP*AP*TP*TP*AP*TP*TP*AP*AP*CP*CP*AP*AP*G)-3', HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
著者Chi, Y.-I, Frantz, J.D, Oh, B.-C, Hansen, L, Dhe-Paganon, S, Shoelson, S.E.
登録日2001-03-30
公開日2002-11-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Diabetes mutations delineate an atypical POU domains in HNF1-Alpha
Mol.Cell, 10, 2002
2XIG
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The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites
分子名称: CITRIC ACID, FERRIC UPTAKE REGULATION PROTEIN, ZINC ION
著者Dian, C, Vitale, S, Leonard, G.A, Fauquant, F, Muller, C, Bahlawane, C, de Reuse, H, Michaud-Soret, I, Terradot, L.
登録日2010-06-29
公開日2011-01-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Structure of the Helicobacter Pylori Ferric Uptake Regulator Fur Reveals Three Functional Metal Binding Sites.
Mol.Microbiol., 79, 2011
2G9W
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Crystal Structure of Rv1846c, a Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis
分子名称: CHLORIDE ION, conserved hypothetical protein
著者Saul, F.A, Haouz, A, Fiez-Vandal, C, Shepard, W, Alzari, P.M.
登録日2006-03-07
公開日2007-03-13
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Genome-wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis
Mol.Microbiol., 71, 2009
3KQH
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Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
分子名称: 5'-D(*AP*AP*AP*AP*AP*A)-3', Serine protease/NTPase/helicase NS3
著者Gu, M, Rice, C.M.
登録日2009-11-17
公開日2010-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010

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