PDB: 30805 件ウェブページステータス検索Chemie searchBIRD

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7UXP	Structure of PDL1 in complex with FP28132, a Helicon Polypeptide 分子名称: AMINO GROUP, FP28132, N,N'-(1,4-phenylene)diacetamide, ... 著者 Li, K, Agarwal, S, Tokareva, O, Thomson, T, Travaline, T, Tattersfield, H, Wahl, S, Verdine, G, McGee, J. 登録日 2022-05-05 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA, 119, 2022
7U9K	Staphylococcus aureus D-alanine-D-alanine ligase in complex with ATP, D-ala-D-ala, Mg2+ and K+ 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, D-alanine--D-alanine ligase, ... 著者 Pederick, J.L, Bruning, J.B. 登録日 2022-03-10 公開日 2023-03-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-guided design and synthesis of ATP-competitive N-acyl-substituted sulfamide d-alanine-d-alanine ligase inhibitors. Bioorg.Med.Chem., 96, 2023
7UXI	Structure of CDK2 in complex with FP19711, a Helicon Polypeptide 分子名称: AMINO GROUP, Cyclin-dependent kinase 2, FP19711, ... 著者 Li, K, Agarwal, S, Tokareva, O, Thomson, T, Wahl, S, Verdine, G, McGee, J. 登録日 2022-05-05 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA, 119, 2022
7TXR	Crystal structure of the Vitronectin hemopexin-like domain binding Calcium-2 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Aleshin, A.E, Marassi, F.M. 登録日 2022-02-09 公開日 2023-03-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for calcium-induced thermostability of human vitronectin To Be Published
6NSI	Crystal structure of Fe(III)-bound YtgA from Chlamydia trachomatis 分子名称: CALCIUM ION, FE (III) ION, Manganese-binding protein, ... 著者 Luo, Z, Campbell, R, Begg, S.L, Kobe, B, McDevitt, C.A. 登録日 2019-01-24 公開日 2019-10-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.00006342 Å) 主引用文献 Structure and Metal Binding Properties of Chlamydia trachomatis YtgA. J.Bacteriol., 202, 2019
8E0E	nbF3:CaV beta subunit 2a complex 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, GLYCEROL, ... 著者 Nirwan, N, Minor, D.L. 登録日 2022-08-09 公開日 2023-01-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Selective posttranslational inhibition of Ca V beta 1 -associated voltage-dependent calcium channels with a functionalized nanobody. Nat Commun, 13, 2022
7NT1	Crystal structure of SARS CoV2 main protease in complex with FSP007 分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE, [(2R)-1-[2-(1H-indol-3-yl)ethylamino]-1-oxidanylidene-butan-2-yl] prop-2-enoate 著者 Oerlemans, R, Eris, D, Wang, M, Sharpe, M, Domling, A, Groves, M.R. 登録日 2021-03-08 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Combining High-Throughput Synthesis and High-Throughput Protein Crystallography for Accelerated Hit Identification. Angew.Chem.Int.Ed.Engl., 60, 2021
6PWZ	Crystal structure of human uridine-cytidine kinase 2 complexed with 2'-azidocytidine 分子名称: 2'-azidocytidine, GLYCEROL, PHOSPHATE ION, ... 著者 Cuthbert, B.J, Goulding, C.W. 登録日 2019-07-24 公開日 2020-07-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Incorporation of novel azido-nucleotides into RNA To Be Published
7UXM	Structure of PPIA in complex with FP29092, a Helicon Polypeptide 分子名称: 1,2-ETHANEDIOL, AMINO GROUP, FP29092, ... 著者 Li, K, Agarwal, S, Tokareva, O, Thomson, T, Wahl, S, Verdine, G, McGee, J. 登録日 2022-05-05 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA, 119, 2022
7OA3	Crystal structure of Chili RNA aptamer in complex with DMHBO+ (Iridium hexammine co-crystallized form) 分子名称: Chili RNA Aptamer, DMHBO+, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Mieczkowski, M, Pena, V, Hoebartner, C. 登録日 2021-04-19 公開日 2021-06-16 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine. Nat Commun, 12, 2021
8RM7	Crystal Structure of Human Androgen Receptor DNA Binding Domain Bound to its Response Element: MMTV-177 GRE/ARE 分子名称: Isoform 2 of Androgen receptor, MMTV-177 GRE/ARE Chain C, MMTV-177 GRE/ARE, ... 著者 Lee, X.Y, Helsen, C, Van Eynde, W, Voet, A, Claessens, F. 登録日 2024-01-05 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural mechanism underlying variations in DNA binding by the androgen receptor. J.Steroid Biochem.Mol.Biol., 241, 2024
7U68	Crystal structure of the Vitronectin hemopexin-like domain binding Sodium-2 分子名称: CHLORIDE ION, SODIUM ION, SULFATE ION, ... 著者 Aleshin, A.E, Marassi, F.M. 登録日 2022-03-03 公開日 2023-03-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for calcium-induced thermostability of human vitronectin To Be Published
7OAW	Crystal structure of the Chili RNA aptamer in complex with DMHBI+ 分子名称: CHLORIDE ION, Chili RNA Aptamer, DMHBI+, ... 著者 Mieczkowski, M, Pena, V, Hoebartner, C. 登録日 2021-04-20 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine. Nat Commun, 12, 2021
6BW6	Human GPT (DPAGT1) H129 variant in complex with tunicamycin 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Tunicamycin, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 著者 Yoo, J, Kuk, A.C.Y, Mashalidis, E.H, Lee, S.-Y. 登録日 2017-12-14 公開日 2018-02-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation. Nat. Struct. Mol. Biol., 25, 2018
8RM6	Crystal Structure of Human Androgen Receptor DNA Binding Domain Bound to its Response Element: C3(1)ARE 分子名称: C3(1)ARE_Chain C, C3(1)ARE_Chain D, Isoform 2 of Androgen receptor, ... 著者 Lee, X.Y, Helsen, C, Van Eynde, W, Voet, A, Claessens, F. 登録日 2024-01-05 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural mechanism underlying variations in DNA binding by the androgen receptor. J.Steroid Biochem.Mol.Biol., 241, 2024
8DPA	Crystal structure of the homodimeric AvrM14-B Nudix hydrolase effector from Melampsora lini 分子名称: AvrM14-B, SULFATE ION 著者 McCombe, C.L, Outram, M.A, Ericsson, D.J, Williams, S.J. 登録日 2022-07-15 公開日 2023-01-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 A rust-fungus Nudix hydrolase effector decaps mRNA in vitro and interferes with plant immune pathways. New Phytol., 239, 2023
6VWU	X-ray structure of ALKS 4230, a fusion of circularly permuted human Interleukin-2 and Interleukin-2 Receptor alpha 分子名称: Interleukin-2,Interleukin-2 receptor subunit alpha 著者 Losey, H.C. 登録日 2020-02-20 公開日 2020-04-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 ALKS 4230: a novel engineered IL-2 fusion protein with an improved cellular selectivity profile for cancer immunotherapy. J Immunother Cancer, 8, 2020
7UX5	Structure of PDL1 in complex with FP28136, a Helicon Polypeptide 分子名称: Helicon FP28136, N,N'-(1,4-phenylene)diacetamide, Programmed cell death 1 ligand 1 著者 Agarwal, S, Li, K, Tokareva, O, Thomson, T, Travaline, T, Wahl, S, Verdine, G, McGee, J. 登録日 2022-05-05 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA, 119, 2022
5BZ2	CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION 分子名称: Na(+)/H(+) antiporter 著者 Coincon, M, Uzdavinys, P, Cameron, A, Drew, D. 登録日 2015-06-11 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters. Nat.Struct.Mol.Biol., 23, 2016
8QCK	Crystal structure of mycothiol disulfide reductase Mtr from Mycobacterium smegmatis 分子名称: Pyridine nucleotide-disulfide oxidoreductase dimerization region 著者 Gutierrez-Fernandez, J, Hammerstad, M, Hersleth, H.-P. 登録日 2023-08-27 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (4.7 Å) 主引用文献 The crystal structure of mycothiol disulfide reductase (Mtr) provides mechanistic insight into the specific low-molecular-weight thiol reductase activity of Actinobacteria. Acta Crystallogr D Struct Biol, 80, 2024
7NQP	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound LvD1009 分子名称: 14-3-3 protein sigma, 2-bromanyl-4-(2-phenylimidazol-1-yl)benzaldehyde, MAGNESIUM ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-03-02 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
8EAZ	HOIL-1/E2-Ub/Ub transthiolation complex 分子名称: RanBP-type and C3HC4-type zinc finger-containing protein 1, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... 著者 Wang, X.S, Cotton, T.R, Lechtenberg, B.C. 登録日 2022-08-30 公開日 2023-01-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family. Nat Commun, 14, 2023
7NRL	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1032 分子名称: 14-3-3 protein sigma, 2-(hydroxymethyl)-5-(2-phenylimidazol-1-yl)phenol, DI(HYDROXYETHYL)ETHER, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-03-04 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
6BZF	Structure of S. cerevisiae Zip2:Spo16 complex, C2 form 分子名称: Protein ZIP2, Sporulation-specific protein 16 著者 Arora, K, Corbett, K.D. 登録日 2017-12-23 公開日 2018-02-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.286 Å) 主引用文献 The conserved XPF:ERCC1-like Zip2:Spo16 complex controls meiotic crossover formation through structure-specific DNA binding. Nucleic Acids Res., 47, 2019
6PY5	Crystal structure of ligand-binding domain of Pseudomonas fluorescens chemoreceptor CtaA in complex with L-serine 分子名称: Putative methyl-accepting chemotaxis protein, SERINE 著者 Ud-Din, I.A, Khan, M.F, Roujeinikova, A. 登録日 2019-07-29 公開日 2020-03-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Broad Specificity of Amino Acid Chemoreceptor CtaA ofPseudomonas fluorescensIs Afforded by Plasticity of Its Amphipathic Ligand-Binding Pocket. Mol.Plant Microbe Interact., 33, 2020

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