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3FSM
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CRYSTAL STRUCTURE OF A CHEMICALLY SYNTHESIZED 203 AMINO ACID 'COVALENT DIMER' [L-Ala51,D-Ala51'] HIV-1 PROTEASE MOLECULE
分子名称: COVALENT DIMER [L-Ala51, D-Ala51'] HIV-1 PROTEASE, N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide
著者Torbeev, V.Y, Kent, S.B.H.
登録日2009-01-10
公開日2010-01-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Protein conformational dynamics in the mechanism of HIV-1 protease catalysis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3JQ3
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Crystal Structure of Lombricine Kinase, complexed with substrate ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lombricine kinase
著者Bush, D.J, Kirillova, O, Clark, S.A, Fabiola, F, Somasundaram, T, Chapman, M.S.
登録日2009-09-05
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献The structure of lombricine kinase: implications for phosphagen kinase conformational changes.
J.Biol.Chem., 286, 2011
3JQO
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Crystal structure of the outer membrane complex of a type IV secretion system
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, LAURYL DIMETHYLAMINE-N-OXIDE, TraF protein, ...
著者Chandran, V, Fronzes, R, Duquerroy, S, Cronin, N, Navaza, J, Waksman, G.
登録日2009-09-07
公開日2009-12-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the outer membrane complex of a type IV secretion system
Nature, 462, 2009
3KA2
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Crystal structure of chemically synthesized 203 amino acid 'covalent dimer' [L-Ala;Gly51']HIV-1 protease molecule complexed with MVT-101 reduced isostere inhibitor at 1.4 A resolution
分子名称: N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, [L-Ala51;Gly51']HIV-1 protease
著者Torbeev, V.Y, Kent, S.B.H.
登録日2009-10-18
公開日2011-04-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Protein conformational dynamics in the mechanism of HIV-1 protease catalysis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3FYG
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CRYSTAL STRUCTURE OF TETRADECA-(3-FLUOROTYROSYL)-GLUTATHIONE S-TRANSFERASE
分子名称: (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE, MU CLASS TETRADECA-(3-FLUOROTYROSYL)-GLUTATHIONE S-TRANSFERASE OF ISOENZYME
著者Xiao, G, Parsons, J.F, Armstrong, R.N, Gilliland, G.L.
登録日1997-08-07
公開日1999-06-01
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conformational changes in the crystal structure of rat glutathione transferase M1-1 with global substitution of 3-fluorotyrosine for tyrosine.
J.Mol.Biol., 281, 1998
3JSC
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CcdBVfi-FormI-pH7.0
分子名称: CcdB, SULFATE ION
著者De Jonge, N, Buts, L, Loris, R.
登録日2009-09-10
公開日2009-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and thermodynamic characterization of vibrio fischeri CCDB
J.Biol.Chem., 285, 2010
3FZ2
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Crystal structure of the tail terminator protein from phage lambda (gpU-D74A)
分子名称: Minor tail protein U, SULFATE ION
著者Pell, L.G, Liu, A, Edmonds, E, Donaldson, L.W, Howell, P.L, Davidson, A.R.
登録日2009-01-23
公開日2009-05-26
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The X-ray crystal structure of the phage lambda tail terminator protein reveals the biologically relevant hexameric ring structure and demonstrates a conserved mechanism of tail termination among diverse long-tailed phages.
J.Mol.Biol., 389, 2009
3GEH
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Crystal structure of MnmE from Nostoc in complex with GDP, FOLINIC ACID and ZN
分子名称: GUANOSINE-5'-DIPHOSPHATE, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ZINC ION, ...
著者Meyer, S, Wittinghofer, A.
登録日2009-02-25
公開日2009-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy
Plos Biol., 7, 2009
3K41
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Crystal structure of sCD-MPR mutant E19Q/K137M bound to Man-6-P
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-beta-D-mannopyranose, Cation-dependent mannose-6-phosphate receptor, ...
著者Olson, L.J, Sun, G, Bohnsack, R.N, Peterson, F.C, Dahms, N.M, Kim, J.J.P.
登録日2009-10-05
公開日2009-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor.
Biochemistry, 49, 2010
3G5F
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Crystallographic analysis of cytochrome P450 cyp121
分子名称: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Belin, P, Le Du, M.H, Gondry, M.
登録日2009-02-05
公開日2009-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis.
Proc.Natl.Acad.Sci.USA, 106, 2009
3GEE
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Crystal structure of MnmE from Chlorobium tepidum in complex with GDP and FOLINIC ACID
分子名称: GUANOSINE-5'-DIPHOSPHATE, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, tRNA modification GTPase mnmE
著者Meyer, S, Wittinghofer, A.
登録日2009-02-25
公開日2009-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy
Plos Biol., 7, 2009
3DZD
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BU of 3dzd by Molmil
Crystal structure of sigma54 activator NTRC4 in the inactive state
分子名称: ADENOSINE-5'-DIPHOSPHATE, SODIUM ION, Transcriptional regulator (NtrC family)
著者Batchelor, J.D, Doucleff, M, Lee, C.-J, Matsubara, K, De Carlo, S, Heideker, J, Lamers, M.M, Pelton, J.G, Wemmer, D.E.
登録日2008-07-29
公開日2008-11-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and regulatory mechanism of Aquifex aeolicus NtrC4: variability and evolution in bacterial transcriptional regulation.
J.Mol.Biol., 384, 2008
3KU7
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BU of 3ku7 by Molmil
Crystal structure of Helicobacter pylori MinE, a cell division topological specificity factor
分子名称: Cell division topological specificity factor
著者Kang, G.B, Song, H.E, Kim, M.K, Eom, S.H.
登録日2009-11-26
公開日2010-05-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Helicobacter pylori MinE, a cell division topological specificity factor
Mol.Microbiol., 76, 2010
3DXS
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BU of 3dxs by Molmil
Crystal structure of a copper binding domain from HMA7, a P-type ATPase
分子名称: Copper-transporting ATPase RAN1, LITHIUM ION, ZINC ION
著者Zimmermann, M, Xiao, Z, Clarke, O.B, Gulbis, J.M, Wedd, A.G.
登録日2008-07-25
公開日2009-08-11
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Metal binding affinities of Arabidopsis zinc and copper transporters: selectivities match the relative, but not the absolute, affinities of their amino-terminal domains.
Biochemistry, 48, 2009
3L59
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Structure of BACE Bound to SCH710413
分子名称: (2Z)-3-(3-chlorobenzyl)-2-imino-5,5-dimethylimidazolidin-4-one, Beta-secretase 1, D(-)-TARTARIC ACID
著者Strickland, C, Zhu, Z.
登録日2009-12-21
公開日2010-02-16
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation
J.Med.Chem., 53, 2010
3DVT
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BU of 3dvt by Molmil
Biochemical and structural characterization of the PAK1- LC8 interaction
分子名称: Dynein light chain 1, cytoplasmic
著者LIghtcap, C.M, Williams, J.C.
登録日2008-07-20
公開日2009-05-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Biochemical and structural characterization of the Pak1-LC8 interaction.
J.Biol.Chem., 283, 2008
3DVH
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LC8 Point mutant K36P
分子名称: Dynein light chain 1, cytoplasmic
著者Lightcap, C.M, Williams, J.C.
登録日2008-07-18
公開日2009-01-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biochemical and structural characterization of the Pak1-LC8 interaction.
J.Biol.Chem., 283, 2008
3DVP
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Pak1 peptide bound LC8
分子名称: Dynein light chain 1, cytoplasmic, P21 activated Kinase peptide
著者Lightcap, C.M, Williams, J.C.
登録日2008-07-18
公開日2009-01-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Biochemical and structural characterization of the Pak1-LC8 interaction.
J.Biol.Chem., 283, 2008
3FZB
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BU of 3fzb by Molmil
Crystal structure of the tail terminator protein from phage lambda (gpU-WT)
分子名称: Minor tail protein U, SULFATE ION
著者Pell, L.G, Liu, A, Edmonds, E, Donaldson, L.W, Howell, P.L, Davidson, A.R.
登録日2009-01-24
公開日2009-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The X-ray crystal structure of the phage lambda tail terminator protein reveals the biologically relevant hexameric ring structure and demonstrates a conserved mechanism of tail termination among diverse long-tailed phages.
J.Mol.Biol., 389, 2009
3FYR
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BU of 3fyr by Molmil
Crystal structure of the sporulation histidine kinase inhibitor Sda from Bacillus subtilis
分子名称: Sporulation inhibitor sda
著者Jacques, D.A, Streamer, M, King, G.F, Guss, J.M, Trewhella, J, Langley, D.B.
登録日2009-01-23
公開日2009-06-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure of the sporulation histidine kinase inhibitor Sda from Bacillus subtilis and insights into its solution state
Acta Crystallogr.,Sect.D, 65, 2009
3FZN
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Intermediate analogue in benzoylformate decarboxylase
分子名称: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, Benzoylformate decarboxylase, CHLORIDE ION, ...
著者Bruning, M, Berheide, M, Meyer, D, Golbik, R, Bartunik, H, Liese, A, Tittmann, K.
登録日2009-01-26
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structural and kinetic studies on native intermediates and an intermediate analogue in benzoylformate decarboxylase reveal a least motion mechanism with an unprecedented short-lived predecarboxylation intermediate.
Biochemistry, 48, 2009
3K42
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Crystal structure of sCD-MPR mutant E19Q/K137M pH 7.0
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cation-dependent mannose-6-phosphate receptor, SN-GLYCEROL-1-PHOSPHATE, ...
著者Olson, L.J, Sun, G, Bohnsack, R.N, Peterson, F.C, Dahms, N.M, Kim, J.J.P.
登録日2009-10-05
公開日2009-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor.
Biochemistry, 49, 2010
3J6D
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Model of the PrgH-PrgK periplasmic rings
分子名称: Pathogenicity 1 island effector protein, Protein PrgH
著者Bergeron, J.R.C, Strynadka, N.C.J.
登録日2014-02-14
公開日2015-01-14
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (11.7 Å)
主引用文献The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body.
Structure, 23, 2015
3K5V
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Structure of Abl kinase in complex with imatinib and GNF-2
分子名称: 3-(6-{[4-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)benzamide, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, CHLORIDE ION, ...
著者Cowan-Jacob, S.W, Fendrich, G, Rummel, G, Strauss, A.
登録日2009-10-08
公開日2010-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.
Nature, 463, 2010
3K77
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X-ray crystal structure of XRCC1
分子名称: DNA repair protein XRCC1
著者Cuneo, M.J, London, R.E.
登録日2009-10-12
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.597 Å)
主引用文献Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.
Proc.Natl.Acad.Sci.USA, 107, 2010

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