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5TIM
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REFINED 1.83 ANGSTROMS STRUCTURE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE, CRYSTALLIZED IN THE PRESENCE OF 2.4 M-AMMONIUM SULPHATE. A COMPARISON WITH THE STRUCTURE OF THE TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE-GLYCEROL-3-PHOSPHATE COMPLEX
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, SULFATE ION, TRIOSEPHOSPHATE ISOMERASE
著者Wierenga, R.K, Hol, W.G.J.
登録日1991-04-23
公開日1992-10-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Refined 1.83 A structure of trypanosomal triosephosphate isomerase crystallized in the presence of 2.4 M-ammonium sulphate. A comparison with the structure of the trypanosomal triosephosphate isomerase-glycerol-3-phosphate complex.
J.Mol.Biol., 220, 1991
2TLI
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THERMOLYSIN (5% ISOPROPANOL SOAKED CRYSTALS)
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ...
著者English, A.C, Done, S.H, Groom, C.R, Hubbard, R.E.
登録日1998-10-28
公開日2000-02-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
1BW0
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CRYSTAL STRUCTURE OF TYROSINE AMINOTRANSFERASE FROM TRYPANOSOMA CRUZI
分子名称: PROTEIN (TYROSINE AMINOTRANSFERASE)
著者Blankenfeldt, W, Montemartini, M, Hunter, G.R, Kalisz, H.M, Nowicki, C, Hecht, H.J.
登録日1998-09-28
公開日1999-09-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Trypanosoma cruzi tyrosine aminotransferase: substrate specificity is influenced by cofactor binding mode.
Protein Sci., 8, 1999
1U6F
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NMR solution structure of TcUBP1, a single RBD-unit from Trypanosoma cruzi
分子名称: RNA-binding protein UBP1
著者Volpon, L, D'orso, I, Frasch, A, Gehring, K.
登録日2004-07-29
公開日2005-01-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR Structural Study of TcUBP1, a Single RRM Domain Protein from Trypanosoma cruzi: Contribution of a beta Hairpin to RNA Binding
Biochemistry, 44, 2005
2TPR
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X-RAY STRUCTURE OF TRYPANOTHIONE REDUCTASE FROM CRITHIDIA FASCICULATA AT 2.4 ANGSTROMS RESOLUTION
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, TRYPANOTHIONE REDUCTASE
著者Kuriyan, J, Kong, X.-P, Krishna, T.S.R.
登録日1991-08-22
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献X-ray structure of trypanothione reductase from Crithidia fasciculata at 2.4-A resolution.
Proc.Natl.Acad.Sci.USA, 88, 1991
1TPF
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COMPARISON OF THE STRUCTURES AND THE CRYSTAL CONTACTS OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE IN FOUR DIFFERENT CRYSTAL FORMS
分子名称: DIMETHYL SULFOXIDE, TRIOSEPHOSPHATE ISOMERASE
著者Radha Kishan, K.V, Zeelen, J.Ph, Wierenga, R.K.
登録日1994-02-28
公開日1994-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Comparison of the structures and the crystal contacts of trypanosomal triosephosphate isomerase in four different crystal forms.
Protein Sci., 3, 1994
3CV0
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Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to T. brucei Phosphoglucoisomerase (PGI) PTS1 peptide
分子名称: 1,2-ETHANEDIOL, Peroxisome targeting signal 1 receptor PEX5, T. brucei PGI PTS1 peptide Ac-FNELSHL
著者Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
登録日2008-04-17
公開日2008-06-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
5T5H
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Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit
分子名称: 40S ribosomal protein L14, 5.8S rRNA, 5S rRNA, ...
著者Liu, Z, Gutierrez-Vargas, C, Wei, J, Grassucci, R.A, Ramesh, M, Espina, N, Sun, M, Tutuncuoglu, B, Madison-Antenucci, S, Woolford Jr, J.L, Tong, L, Frank, J.
登録日2016-08-31
公開日2016-10-12
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (2.54 Å)
主引用文献Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.
Proc.Natl.Acad.Sci.USA, 113, 2016
3B9G
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Crystal structure of loop deletion mutant of Trypanosoma vivax nucleoside hydrolase (3GTvNH) in complex with ImmH
分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, CALCIUM ION, IAG-nucleoside hydrolase, ...
著者Vandemeulebroucke, A, De Vos, S, Van Holsbeke, E, Steyaert, J, Versees, W.
登録日2007-11-05
公開日2008-04-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A Flexible Loop as a Functional Element in the Catalytic Mechanism of Nucleoside Hydrolase from Trypanosoma vivax.
J.Biol.Chem., 283, 2008
3G1Q
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Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma brucei in ligand free state
分子名称: PROTOPORPHYRIN IX CONTAINING FE, Sterol 14-alpha-demethylase
著者Lepesheva, G.I, Hargrove, T.Y, Harp, J, Wawrzak, Z, Waterman, M.R, Park, H.
登録日2009-01-30
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections.
J.Biol.Chem., 285, 2010
1TPE
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COMPARISON OF THE STRUCTURES AND THE CRYSTAL CONTACTS OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE IN FOUR DIFFERENT CRYSTAL FORMS
分子名称: TRIOSEPHOSPHATE ISOMERASE
著者Noble, M.E.M, Radha Kishan, K.V, Zeelen, J.Ph, Wierenga, R.K.
登録日1994-02-28
公開日1994-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Comparison of the structures and the crystal contacts of trypanosomal triosephosphate isomerase in four different crystal forms.
Protein Sci., 3, 1994
5TLI
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THERMOLYSIN (60% ISOPROPANOL SOAKED CRYSTALS)
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ...
著者English, A.C, Done, S.H, Groom, C.R, Hubbard, R.E.
登録日1998-10-29
公開日2000-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
3GW9
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Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma brucei bound to an inhibitor N-(1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxaziazol-2-yl)benzamide
分子名称: N-[(1R)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14ALPHA-DEMETHYLASE
著者Lepesheva, G.I, Hargrove, T.Y, Harp, J, Wawrzak, Z, Waterman, M.R.
登録日2009-03-31
公開日2009-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections.
J.Biol.Chem., 285, 2010
1TRD
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THE INFLUENCE OF CRYSTAL PACKING ON CRYSTALLOGRAPHIC BINDING STUDIES: A NEW CRYSTAL FORM OF TRYPANOSOMAL TIM
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Noble, M.E.M, Wierenga, R.K.
登録日1992-10-06
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the "open" and "closed" state of trypanosomal triosephosphate isomerase, as observed in a new crystal form: implications for the reaction mechanism.
Proteins, 16, 1993
3H4C
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Structure of the C-terminal Domain of Transcription Factor IIB from Trypanosoma brucei
分子名称: 1,2-ETHANEDIOL, Transcription factor TFIIB-like
著者Syed Ibrahim, B, Kanneganti, N, Rieckhof, G.E, Das, A, Laurents, D.V, Palenchar, J.B, Bellofatto, V, Wah, D.A.
登録日2009-04-18
公開日2009-08-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the C-terminal domain of transcription factor IIB from Trypanosoma brucei.
Proc.Natl.Acad.Sci.USA, 106, 2009
1TPD
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STRUCTURES OF THE "OPEN" AND "CLOSED" STATE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE, AS OBSERVED IN A NEW CRYSTAL FORM: IMPLICATIONS FOR THE REACTION MECHANISM
分子名称: TRIOSEPHOSPHATE ISOMERASE
著者Noble, M.E.M, Zeelen, J.Ph, Wierenga, R.K.
登録日1994-02-28
公開日1994-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of the "open" and "closed" state of trypanosomal triosephosphate isomerase, as observed in a new crystal form: implications for the reaction mechanism.
Proteins, 16, 1993
3CVN
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Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to T. brucei Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) PTS1 peptide
分子名称: 1,2-ETHANEDIOL, Peroxisome targeting signal 1 receptor, T. brucei GAPDH PTS1 peptide Ac-DRDAAKL
著者Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
登録日2008-04-18
公開日2008-06-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
4TLI
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THERMOLYSIN (25% ISOPROPANOL SOAKED CRYSTALS)
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ...
著者English, A.C, Done, S.H, Groom, C.R, Hubbard, R.E.
登録日1998-10-29
公開日2000-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
1CI1
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CRYSTAL STRUCTURE OF TRIOSEPHOSPHATE ISOMERASE FROM TRYPANOSOMA CRUZI IN HEXANE
分子名称: HEXANE, PROTEIN (TRIOSEPHOSPHATE ISOMERASE)
著者Gao, X.-G, Maldondo, E, Perez-Montfort, R, De Gomez-Puyou, M.T, Gomez-Puyou, A, Rodriguez-Romero, A.
登録日1999-04-06
公開日1999-09-01
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of triosephosphate isomerase from Trypanosoma cruzi in hexane.
Proc.Natl.Acad.Sci.USA, 96, 1999
1TC1
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A 1.4 ANGSTROM CRYSTAL STRUCTURE FOR THE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE OF TRYPANOSOMA CRUZI
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FORMYCIN B, PROTEIN (HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE)
著者Focia, P.J, Craig III, S.P, Nieves-Alicea, R, Fletterick, R.J, Eakin, A.E.
登録日1998-09-30
公開日1999-10-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献A 1.4 A crystal structure for the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi.
Biochemistry, 37, 1998
4TIM
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CRYSTALLOGRAPHIC AND MOLECULAR MODELING STUDIES ON TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE: A CRITICAL ASSESSMENT OF THE PREDICTED AND OBSERVED STRUCTURES OF THE COMPLEX WITH 2-PHOSPHOGLYCERATE
分子名称: 2-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Nobel, M.E.M, Wierenga, R.K, Hol, W.G.J.
登録日1991-04-11
公開日1992-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystallographic and molecular modeling studies on trypanosomal triosephosphate isomerase: a critical assessment of the predicted and observed structures of the complex with 2-phosphoglycerate.
J.Med.Chem., 34, 1991
3BJE
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Crystal structure of Trypanosoma brucei nucleoside phosphorylase shows uridine phosphorylase activity
分子名称: 1-O-phosphono-alpha-D-ribofuranose, CALCIUM ION, Nucleoside phosphorylase, ...
著者Larson, E.T, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2007-12-03
公開日2007-12-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献The Crystal Structure and Activity of a Putative Trypanosomal Nucleoside Phosphorylase Reveal It to be a Homodimeric Uridine Phosphorylase
J.Mol.Biol., 396, 2010
8GYP
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Cryo-EM structure of human Pannexin-3 in closed state.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Pannexin-3
著者Cong, Y, Jin, X, Kong, F, Yan, C.
登録日2022-09-23
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Inner channel lipids regulated gating mechanism of human pannexins.
To Be Published
8GYO
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Inner channel lipids regulated gating mechanism of human pannexins.
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Digitonin, ...
著者Cong, Y, Jin, X, Kong, F, Yan, C.
登録日2022-09-23
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Inner channel lipids regulated gating mechanism of human pannexins.
To Be Published
8GYT
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Cryo-EM structure of human Pannexin-3 R36S/F40R variant in pre-open state.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Pannexin-3
著者Cong, Y, Jin, X, Kong, F, Wu, T, Yan, C.
登録日2022-09-23
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Inner channel lipids regulated gating mechanism of human pannexins.
To Be Published

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