2XFO
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![BU of 2xfo by Molmil](/molmil-images/mine/2xfo) | tranylcypromine-inhibited human monoamine oxidase B Ile199Ala mutant in complex with 2-(2-benzofuranyl)-2-imidazoline | 分子名称: | 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, 3-PHENYLPROPANAL, Amine oxidase [flavin-containing] B, ... | 著者 | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | 登録日 | 2010-05-26 | 公開日 | 2010-10-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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2XFP
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![BU of 2xfp by Molmil](/molmil-images/mine/2xfp) | Isatin-inhibited human monoamine oxidase B in complex with 2-(2- benzofuranyl)-2-imidazoline | 分子名称: | 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | 登録日 | 2010-05-26 | 公開日 | 2010-10-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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7GPB
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![BU of 7gpb by Molmil](/molmil-images/mine/7gpb) | STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Barford, D, Hu, S.-H, Johnson, L.N. | 登録日 | 1990-11-13 | 公開日 | 1992-10-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP. J.Mol.Biol., 218, 1991
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5DO0
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![BU of 5do0 by Molmil](/molmil-images/mine/5do0) | The structure of PKMT1 from Rickettsia prowazekii | 分子名称: | protein lysine methyltransferase 1 | 著者 | Noinaj, N, Abeykoon, A, He, Y, Yang, D.C, Buchanan, S.K. | 登録日 | 2015-09-10 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Insights into Substrate Recognition and Catalysis in Outer Membrane Protein B (OmpB) by Protein-lysine Methyltransferases from Rickettsia. J.Biol.Chem., 291, 2016
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2XCG
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![BU of 2xcg by Molmil](/molmil-images/mine/2xcg) | Tranylcypromine-inhibited human monoamine oxidase B in complex with 2- (2-benzofuranyl)-2-imidazoline | 分子名称: | 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, 3-PHENYLPROPANAL, Amine oxidase [flavin-containing] B, ... | 著者 | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | 登録日 | 2010-04-23 | 公開日 | 2010-10-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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2V60
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![BU of 2v60 by Molmil](/molmil-images/mine/2v60) | Structure of human MAO B in complex with the selective inhibitor 7-(3- chlorobenzyloxy)-4-carboxaldehyde-coumarin | 分子名称: | 7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE, AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Binda, C, Wang, J, Pisani, L, Caccia, C, Carotti, A, Salvati, P, Edmondson, D.E, Mattevi, A. | 登録日 | 2007-07-12 | 公開日 | 2007-10-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs. J.Med.Chem., 50, 2007
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2V61
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![BU of 2v61 by Molmil](/molmil-images/mine/2v61) | Structure of human MAO B in complex with the selective inhibitor 7-(3- chlorobenzyloxy)-4-(methylamino)methyl-coumarin | 分子名称: | 7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE, AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Binda, C, Wang, J, Pisani, L, Caccia, C, Carotti, A, Salvati, P, Edmondson, D.E, Mattevi, A. | 登録日 | 2007-07-13 | 公開日 | 2007-10-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs. J.Med.Chem., 50, 2007
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2XFQ
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![BU of 2xfq by Molmil](/molmil-images/mine/2xfq) | Rasagiline-inhibited human monoamine oxidase B in complex with 2-(2- benzofuranyl)-2-imidazoline | 分子名称: | (1R)-N-(prop-2-en-1-yl)-2,3-dihydro-1H-inden-1-amine, 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, Amine oxidase [flavin-containing] B, ... | 著者 | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | 登録日 | 2010-05-26 | 公開日 | 2010-10-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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4L2M
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![BU of 4l2m by Molmil](/molmil-images/mine/4l2m) | Crystal structure of the 2/2 hemoglobin from Synechococcus sp. PCC 7002 in the cyanomet state and with covalently attached heme | 分子名称: | CYANIDE ION, Cyanoglobin, HEME B/C, ... | 著者 | Wenke, B.B, Schlessman, J.L, Heroux, A, Lecomte, J.T.J. | 登録日 | 2013-06-04 | 公開日 | 2013-06-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | The 2/2 hemoglobin from the cyanobacterium Synechococcus sp. PCC 7002 with covalently attached heme: Comparison of X-ray and NMR structures. Proteins, 82, 2014
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3MUS
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![BU of 3mus by Molmil](/molmil-images/mine/3mus) | 2A Resolution Structure of Rat Type B Cytochrome b5 | 分子名称: | Cytochrome b5 type B, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Terzyan, S, Zhang, X, Benson, D.R. | 登録日 | 2010-05-03 | 公開日 | 2011-04-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Accommodating a Non-Conservative Internal Mutation by Water-Mediated Hydrogen-Bonding Between beta-Sheet Strands: A Comparison of Human and Rat Type B (Mitochondrial) Cytochrome b5 Biochemistry, 50, 2011
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7DSX
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![BU of 7dsx by Molmil](/molmil-images/mine/7dsx) | Structure of a human NHE1-CHP1 complex under pH 7.5, bound by cariporide | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Calcineurin B homologous protein 1, N-[bis(azanyl)methylidene]-3-methylsulfonyl-4-propan-2-yl-benzamide, ... | 著者 | Dong, Y, Gao, Y, Li, B, Zhang, X.C, Zhao, Y. | 登録日 | 2021-01-03 | 公開日 | 2021-06-23 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure and mechanism of the human NHE1-CHP1 complex. Nat Commun, 12, 2021
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5T8P
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![BU of 5t8p by Molmil](/molmil-images/mine/5t8p) | Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to benzoxepin compound 2 | 分子名称: | 6,7-dihydrothieno[4,5]oxepino[1,2-~{c}]pyridine-2-carboxamide, Mitogen-activated protein kinase kinase kinase 14, SULFATE ION | 著者 | Smith, M.A, McEwan, P.A. | 登録日 | 2016-09-08 | 公開日 | 2017-01-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Structure-Based Design of Tricyclic NF-kappa B Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K). J. Med. Chem., 60, 2017
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6U50
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![BU of 6u50 by Molmil](/molmil-images/mine/6u50) | Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) | 著者 | Taylor, A.B, Sherwood, L.J, Hart, P.J, Hayhurst, A. | 登録日 | 2019-08-26 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins. J.Mol.Biol., 431, 2019
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5TLP
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![BU of 5tlp by Molmil](/molmil-images/mine/5tlp) | Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-BSC Analog, 3-fluorophenyl (1R,2R,4S)-5-(4-hydroxyphenyl)-6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate and 3-methyl-6-phenyl-3H-imidazo[4,5-b]pyridin-2-amine | 分子名称: | 3-fluorophenyl (1S,2R,4S)-5-(4-hydroxyphenyl)-6-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate, 3-methyl-6-phenyl-3H-imidazo[4,5-b]pyridin-2-amine, Estrogen receptor, ... | 著者 | Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Nowak, J, Kojetin, D.J, Elemento, O, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2016-10-11 | 公開日 | 2017-01-18 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies. Cell Chem Biol, 24, 2017
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6A6I
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![BU of 6a6i by Molmil](/molmil-images/mine/6a6i) | Crystal structure of the winged-helix domain of Cockayne syndrome group B protein in complex with ubiquitin | 分子名称: | CHLORIDE ION, Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant, ... | 著者 | Takahashi, T.S, Sato, Y, Fukai, S. | 登録日 | 2018-06-28 | 公開日 | 2019-02-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of ubiquitin recognition by the winged-helix domain of Cockayne syndrome group B protein. Nucleic Acids Res., 47, 2019
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5IFA
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![BU of 5ifa by Molmil](/molmil-images/mine/5ifa) | |
3NBD
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![BU of 3nbd by Molmil](/molmil-images/mine/3nbd) | Clitocybe nebularis ricin B-like lectin (CNL) in complex with lactose, crystallized at pH 7.1 | 分子名称: | Ricin B-like lectin, SULFATE ION, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Renko, M, Pohleven, J, Sabotic, J, Kos, J, Turk, D. | 登録日 | 2010-06-03 | 公開日 | 2011-09-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Bivalent carbohydrate binding is required for biological activity of Clitocybe nebularis lectin (CNL), the N,N'-diacetyllactosediamine (GalNAc beta 1-4GlcNAc, LacdiNAc)-specific lectin from basidiomycete C. nebularis J.Biol.Chem., 287, 2012
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3K36
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6J10
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![BU of 6j10 by Molmil](/molmil-images/mine/6j10) | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly | 分子名称: | 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one, Capsid protein | 著者 | Park, S, Jin, M.S, Cho, Y, Kang, J, Kim, S, Park, M, Park, H, Kim, J, Park, S, Hwang, J, Kim, Y, Kim, Y.J. | 登録日 | 2018-12-27 | 公開日 | 2019-04-17 | 最終更新日 | 2019-05-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly. Nat Commun, 10, 2019
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2WA6
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![BU of 2wa6 by Molmil](/molmil-images/mine/2wa6) | Structure of the W148R mutant of human filamin b actin binding domain at 1.95 Angstrom resolution | 分子名称: | CARBONATE ION, FILAMIN-B | 著者 | Sawyer, G.M, Clark, A.R, Robertson, S.P, Sutherland-Smith, A.J. | 登録日 | 2009-02-03 | 公開日 | 2009-06-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Disease-Associated Substitutions in the Filamin B Actin Binding Domain Confer Enhanced Actin Binding Affinity in the Absence of Major Structural Disturbance: Insights from the Crystal Structures of Filamin B Actin Binding Domains. J.Mol.Biol., 390, 2009
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5UKP
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![BU of 5ukp by Molmil](/molmil-images/mine/5ukp) | |
5UKN
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7WT4
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![BU of 7wt4 by Molmil](/molmil-images/mine/7wt4) | Crystal structure of HLA-A*2402 complexed with 8-mer Influenza PB1 peptide | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | 著者 | Asa, M, Morita, D, Sugita, M. | 登録日 | 2022-02-03 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.89459145 Å) | 主引用文献 | Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding. J.Biol.Chem., 298, 2022
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7WT5
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![BU of 7wt5 by Molmil](/molmil-images/mine/7wt5) | Crystal structure of HLA-A*2450 complexed with 8-mer model peptide | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 8-mer model peptide, ... | 著者 | Asa, M, Morita, D, Sugita, M. | 登録日 | 2022-02-03 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.0950768 Å) | 主引用文献 | Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding. J.Biol.Chem., 298, 2022
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7WT3
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![BU of 7wt3 by Molmil](/molmil-images/mine/7wt3) | Crystal structure of HLA-A*2402 complexed with 4-mer lipopeptide | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-mer lipopeptide, ... | 著者 | Asa, M, Morita, D, Sugita, M. | 登録日 | 2022-02-03 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.887655 Å) | 主引用文献 | Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding. J.Biol.Chem., 298, 2022
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