6JQ2
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![BU of 6jq2 by Molmil](/molmil-images/mine/6jq2) | Crystal Structure of H2-Kb in complex with a DPAGT1 self-peptide | 分子名称: | Beta-2-microglobulin, DPATG1 antigen SIIVFNLV, H-2 class I histocompatibility antigen, ... | 著者 | Bai, P, Yin, L. | 登録日 | 2019-03-28 | 公開日 | 2020-04-01 | 最終更新日 | 2021-02-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
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4LCW
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![BU of 4lcw by Molmil](/molmil-images/mine/4lcw) | The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH | 分子名称: | 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Patel, O, Rossjohn, J. | 登録日 | 2013-06-24 | 公開日 | 2013-10-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. J.Exp.Med., 210, 2013
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3MRH
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![BU of 3mrh by Molmil](/molmil-images/mine/3mrh) | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide N3S variant | 分子名称: | 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Reiser, J.-B, Chouquet, A, Le Gorrec, M, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans. J.Immunol., 193, 2014
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3L3J
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![BU of 3l3j by Molmil](/molmil-images/mine/3l3j) | Crystal structure of HLA-B*4402 in complex with the F3A/R5A double mutant of a self-peptide derived from DPA*0201 | 分子名称: | ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Theodossis, A, Ely, L.K, Rossjohn, J. | 登録日 | 2009-12-17 | 公開日 | 2010-03-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition Proc.Natl.Acad.Sci.USA, 107, 2010
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5BS0
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![BU of 5bs0 by Molmil](/molmil-images/mine/5bs0) | MAGE-A3 Reactive TCR in complex with Titin Epitope in HLA-A1 | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, Lomax, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K. | 登録日 | 2015-06-01 | 公開日 | 2016-03-02 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy. Sci Rep, 6, 2016
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6BIL
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![BU of 6bil by Molmil](/molmil-images/mine/6bil) | HLA-DRB1 in complex with citrullinated fibrinogen peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta 74cit69-81, HLA class II histocompatibility antigen, ... | 著者 | Ting, Y.T, Scally, S.W, Rossjohn, J. | 登録日 | 2017-11-02 | 公開日 | 2018-01-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis. J. Biol. Chem., 293, 2018
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1I3R
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![BU of 1i3r by Molmil](/molmil-images/mine/1i3r) | CRYSTAL STRUCTURE OF A MUTANT IEK CLASS II MHC MOLECULE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FUSION PROTEIN CONSISTING OF MHC E-BETA-K PRECURSOR, ... | 著者 | Kappler, J.W, Wilson, N. | 登録日 | 2001-02-15 | 公開日 | 2001-06-20 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mutations changing the kinetics of class II MHC peptide exchange. Immunity, 14, 2001
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6CQL
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![BU of 6cql by Molmil](/molmil-images/mine/6cql) | Crystal structure of F24 TCR -DR11-RQ13 peptide complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F24 alpha chain, F24 beta Chain, ... | 著者 | Farenc, C, Gras, S, Rossjohn, J. | 登録日 | 2018-03-15 | 公開日 | 2018-06-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | CD4+T cell-mediated HLA class II cross-restriction in HIV controllers. Sci Immunol, 3, 2018
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8DV4
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![BU of 8dv4 by Molmil](/molmil-images/mine/8dv4) | Crystal structure of the BC8B TCR-CD1b-PI complex | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Farquhar, R, Rossjohn, J, Shahine, A. | 登録日 | 2022-07-28 | 公開日 | 2023-04-19 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | alpha beta T-cell receptor recognition of self-phosphatidylinositol presented by CD1b. J.Biol.Chem., 299, 2023
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4PRI
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![BU of 4pri by Molmil](/molmil-images/mine/4pri) | Crystal structure of TK3 TCR-HLA-B*35:08-HPVG complex | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, Epstein-Barr nuclear antigen 1, ... | 著者 | Yu Chih, L, Rossjohn, J, Gras, S. | 登録日 | 2014-03-05 | 公開日 | 2014-04-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism. J.Biol.Chem., 289, 2014
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1JK8
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![BU of 1jk8 by Molmil](/molmil-images/mine/1jk8) | |
6H6H
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![BU of 6h6h by Molmil](/molmil-images/mine/6h6h) | |
1A4K
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![BU of 1a4k by Molmil](/molmil-images/mine/1a4k) | DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE | 分子名称: | ANTIBODY FAB, CADMIUM ION, [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID | 著者 | Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. | 登録日 | 1998-01-30 | 公開日 | 1998-05-13 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Immunological origins of binding and catalysis in a Diels-Alderase antibody. Science, 279, 1998
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6CPO
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![BU of 6cpo by Molmil](/molmil-images/mine/6cpo) | Crystal structure of DR15 presenting the RQ13 peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | 著者 | Farenc, C, Gras, S, Rossjohn, J. | 登録日 | 2018-03-13 | 公開日 | 2018-06-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | CD4+T cell-mediated HLA class II cross-restriction in HIV controllers. Sci Immunol, 3, 2018
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4K71
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![BU of 4k71 by Molmil](/molmil-images/mine/4k71) | Crystal structure of a high affinity Human Serum Albumin variant bound to the Neonatal Fc Receptor | 分子名称: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51, SULFATE ION, ... | 著者 | Schmidt, M.M, Townson, S.A, Andreucci, A, Dombrowski, C, Erbe, D.V, King, B, Kovalchin, J.T, Masci, A, Murillo, A, Schirmer, E.B, Furfine, E.S, Barnes, T.M. | 登録日 | 2013-04-16 | 公開日 | 2013-10-23 | 最終更新日 | 2014-02-05 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of an HSA/FcRn complex reveals recycling by competitive mimicry of HSA ligands at a pH-dependent hydrophobic interface. Structure, 21, 2013
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7UMG
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![BU of 7umg by Molmil](/molmil-images/mine/7umg) | Crystal structure of human CD8aa-MR1-Ac-6-FP complex | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, Major histocompatibility complex class I-related gene protein, ... | 著者 | Awad, W, Rossjohn, J. | 登録日 | 2022-04-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells. J.Exp.Med., 219, 2022
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5HGB
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![BU of 5hgb by Molmil](/molmil-images/mine/5hgb) | HLA*A2402 complexed with HIV nef138 8mer epitope | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | 著者 | Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2016-01-08 | 公開日 | 2016-06-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Effects of a Single Escape Mutation on T Cell and HIV-1 Co-adaptation. Cell Rep, 15, 2016
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1HOC
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![BU of 1hoc by Molmil](/molmil-images/mine/1hoc) | THE THREE-DIMENSIONAL STRUCTURE OF H-2DB AT 2.4 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ANTIGEN-DETERMINANT SELECTION | 分子名称: | 9-RESIDUE PEPTIDE, BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (H2-DB) (ALPHA CHAIN) | 著者 | Young, A.C.M, Zhang, W, Sacchettini, J.C. | 登録日 | 1994-01-02 | 公開日 | 1994-04-30 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The three-dimensional structure of H-2Db at 2.4 A resolution: implications for antigen-determinant selection Cell(Cambridge,Mass.), 76, 1994
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4G8G
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![BU of 4g8g by Molmil](/molmil-images/mine/4g8g) | Crystal Structure of C12C TCR-HA B2705-KK10 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ... | 著者 | Gras, S, Wilmann, P.G, Rossjohn, J. | 登録日 | 2012-07-23 | 公開日 | 2013-03-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells. Immunity, 38, 2013
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1LD9
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![BU of 1ld9 by Molmil](/molmil-images/mine/1ld9) | THE THREE-DIMENSIONAL STRUCTURE OF AN H-2LD PEPTIDE COMPLEX EXPLAINS THE UNIQUE INTERACTION OF LD WITH BETA2M AND PEPTIDE | 分子名称: | BETA-2 MICROGLOBULIN, MHC CLASS I H-2LD HEAVY CHAIN, NANO-PEPTIDE | 著者 | Balendiran, G.K, Solheim, J.C, Young, A.C.M, Hansen, T.H, Nathenson, S.G, Sacchettini, J.C. | 登録日 | 1997-04-24 | 公開日 | 1998-05-06 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The three-dimensional structure of an H-2Ld-peptide complex explains the unique interaction of Ld with beta-2 microglobulin and peptide. Proc.Natl.Acad.Sci.USA, 94, 1997
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6CX5
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![BU of 6cx5 by Molmil](/molmil-images/mine/6cx5) | Structure of alpha-GSA[8,8P] bound by CD1d and in complex with the Va14Vb8.2 TCR | 分子名称: | (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(8-phenyloctyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octanamide (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, J, Zajonc, D. | 登録日 | 2018-04-02 | 公開日 | 2019-04-10 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides. J.Biol.Chem., 294, 2019
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6CHF
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![BU of 6chf by Molmil](/molmil-images/mine/6chf) | Crystal structure of a Fc fragment LALA mutant (L234A, L235A) of human IgG1 (crystal form 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Uncharacterized protein DKFZp686C11235 | 著者 | Gohain, N, Tolbert, W.D, Pazgier, M. | 登録日 | 2018-02-22 | 公開日 | 2019-02-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fc gamma Receptor Binding. Structure, 2020
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6CUG
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![BU of 6cug by Molmil](/molmil-images/mine/6cug) | Crystal structure of BC8B TCR-CD1b-PC complex | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | 著者 | Shahine, A.E, Rossjohn, J. | 登録日 | 2018-03-26 | 公開日 | 2019-01-16 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids. Nat Commun, 10, 2019
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7K80
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![BU of 7k80 by Molmil](/molmil-images/mine/7k80) | KIR3DL1*001 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, ... | 著者 | MacLachlan, B.J, Rossjohn, J, Vivian, J.P. | 登録日 | 2020-09-24 | 公開日 | 2020-12-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1. J Immunol., 206, 2021
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1SYS
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![BU of 1sys by Molmil](/molmil-images/mine/1sys) | Crystal structure of HLA, B*4403, and peptide EEPTVIKKY | 分子名称: | Beta-2-microglobulin, Sorting nexin 5, leukocyte antigen (HLA) class I molecule | 著者 | Zernich, D, Purcell, A.W, Macdonald, W.A, Kjer-Nielsen, L, Ely, L.K, Laham, N, Crockford, T, Mifsud, N.A, Tait, B.D, Holdsworth, R, Brooks, A.G, Bottomley, S.P, Beddoe, T, Peh, C.A, Rossjohn, J, McCluskey, J. | 登録日 | 2004-04-01 | 公開日 | 2004-10-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion J.Exp.Med., 200, 2004
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